Temporal dynamics of the host molecular responses underlying severe COVID-19 progression and disease resolution

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

A genome-wide transcriptomic analysis of protein-coding genes in human blood cells

(2020) Mathias Uhlen et al.   SCIENCE

Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients

(2020) Zhuo Zhou et al.   Cell Host & Microbe

Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure

(2020) Evangelos J. Giamarellos-Bourboulis et al.   Cell Host & Microbe

A Dynamic Immune Response Shapes COVID-19 Progression

(2020) Eugenia Ziying Ong et al.   Cell Host & Microbe

Targeting potential drivers of COVID-19: Neutrophil extracellular traps

(2020) Betsy J. Barnes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Trials of anti-tumour necrosis factor therapy for COVID-19 are urgently needed

(2020) Marc Feldmann et al.   LANCET

Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations

(2020) Jason Phua et al.   Lancet Respiratory Medicine

Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients

(2020) Jing Liu et al.   EBioMedicine

Gender Differences in Patients With COVID-19: Focus on Severity and Mortality

(2020) Jian-Min Jin et al.   Frontiers in Public Health

Interleukin-6 blockade with sarilumab in severe COVID-19 pneumonia with systemic hyperinflammation: an open-label cohort study

(2020) Emanuel Della-Torre et al.   ANNALS OF THE RHEUMATIC DISEASES

Elevated calprotectin and abnormal myeloid cell subsets discriminate severe from mild COVID-19

(2020) Aymeric Silvin et al.   CELL

The Global Phosphorylation Landscape of SARS-CoV-2 Infection

(2020) Mehdi Bouhaddou et al.   CELL

Retrospective Multicenter Cohort Study Shows Early Interferon Therapy Is Associated with Favorable Clinical Responses in COVID-19 Patients

(2020) Nan Wang et al.   Cell Host & Microbe

Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2

(2020) Markus Hoffmann et al.   NATURE

Longitudinal analyses reveal immunological misfiring in severe COVID-19

(2020) Carolina Lucas et al.   NATURE

Early IL-1 receptor blockade in severe inflammatory respiratory failure complicating COVID-19

(2020) Raphaël Cauchois et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

(2020) Divij Mathew et al.   SCIENCE

Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia

(2020) Sara De Biasi et al.   Nature Communications

Transcriptome-based drug repositioning for coronavirus disease 2019 (COVID-19)

(2020) Zhilong Jia et al.   Pathogens and Disease

Immune and Metabolic Signatures of COVID-19 Revealed by Transcriptomics Data Reuse

(2020) Luiz G. Gardinassi et al.   Frontiers in Immunology

Aspirin Use is Associated with Decreased Mechanical Ventilation, ICU Admission, and In-Hospital Mortality in Hospitalized Patients with COVID-19

(2020) Jonathan H. Chow et al.   ANESTHESIA AND ANALGESIA

Lactate dehydrogenase and C-reactive protein as predictors of respiratory failure in CoVID-19 patients

(2020) Erika Poggiali et al.   CLINICA CHIMICA ACTA

Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19

(2020) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Azithromycin in addition to standard of care versus standard of care alone in the treatment of patients admitted to the hospital with severe COVID-19 in Brazil (COALITION II): a randomised clinical trial

(2020) Remo H M Furtado et al.   LANCET

Sex differences in immune responses that underlie COVID-19 disease outcomes

(2020) Takehiro Takahashi et al.   NATURE

Transcriptional and proteomic insights into the host response in fatal COVID-19 cases

(2020) Meng Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans

(2020) Prabhu S. Arunachalam et al.   SCIENCE

Excessive Neutrophils and Neutrophil Extracellular Traps in COVID-19

(2020) Jun Wang et al.   Frontiers in Immunology

Author Correction: A dynamic COVID-19 immune signature includes associations with poor prognosis

(2020) Adam G. Laing et al.   NATURE MEDICINE

The transcriptomic profiling of SARS-CoV-2 compared to SARS, MERS, EBOV, and H1N1

(2020) Alsamman M. Alsamman et al.   PLoS One

Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission

(2020) Hannah Peckham et al.   Nature Communications

Determining cell type abundance and expression from bulk tissues with digital cytometry

(2019) Aaron M. Newman et al.   NATURE BIOTECHNOLOGY

Genomic signature of early T-cell response is associated with lower antibody titer threshold for sterilizing immunity

(2019) Eugenia Z. Ong et al.   ANTIVIRAL RESEARCH

Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection

(2019) Benjamin M. Tang et al.   Nature Communications

S100A8/A9 in Inflammation

(2018) Siwen Wang et al.   Frontiers in Immunology

DGIdb 3.0: a redesign and expansion of the drug–gene interaction database

(2017) Kelsy C Cotto et al.   NUCLEIC ACIDS RESEARCH

A Role for Neutrophils in Viral Respiratory Disease

(2017) Jeremy V. Camp et al.   Frontiers in Immunology

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

The Influenza Virus Protein PB1-F2 Increases Viral Pathogenesis through Neutrophil Recruitment and NK Cells Inhibition

(2016) Aurore Vidy et al.   PLoS One

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms

(2011) Fran Supek et al.   PLoS One

Interferon-stimulated genes and their antiviral effector functions

(2011) John W Schoggins et al.   Current Opinion in Virology

RegPhos: a system to explore the protein kinase–substrate phosphorylation network in humans

(2010) Tzong-Yi Lee et al.   NUCLEIC ACIDS RESEARCH