The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies

The human milk oligosaccharides 2’-fucosyllactose and 6’-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 signaling

(2020) Chhinder P. Sodhi et al.   PEDIATRIC RESEARCH

Nutrition and the Immune System: A Complicated Tango

(2020) Carina Venter et al.   Nutrients

TLR2 and Dectin-1 Signaling in Mouse Hematopoietic Stem and Progenitor Cells Impacts the Ability of the Antigen Presenting Cells They Produce to Activate CD4 T Cells

(2020) Alba Martínez et al.   Cells

How the AHR Became Important in Intestinal Homeostasis—A Diurnal FICZ/AHR/CYP1A1 Feedback Controls Both Immunity and Immunopathology

(2020) Agneta Rannug   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dectin-1 Stimulation of Hematopoietic Stem and Progenitor Cells Occurs In Vivo and Promotes Differentiation Toward Trained Macrophages via an Indirect Cell-Autonomous Mechanism

(2020) Cristina Bono et al.   mBio

Anti-Pathogenic Functions of Non-Digestible Oligosaccharides In Vitro

(2020) Mostafa Asadpoor et al.   Nutrients

Colonization by Enterobacteriaceae is crucial for acute inflammatory responses in murine small intestine via regulation of corticosterone production

(2020) Zélia Menezes-Garcia et al.   Gut Microbes

What is new in the exposome?

(2020) Paolo Vineis et al.   ENVIRONMENT INTERNATIONAL

Trained immunity, tolerance, priming and differentiation: distinct immunological processes

(2020) Maziar Divangahi et al.   NATURE IMMUNOLOGY

LncRNA lncLy6C induced by microbiota metabolite butyrate promotes differentiation of Ly6Chigh to Ly6Cint/neg macrophages through lncLy6C/C/EBPβ/Nr4A1 axis

(2020) Yunhuan Gao et al.   Cell Discovery

Intestinal Microbiota as a Host Defense Mechanism to Infectious Threats

(2019) Simona Iacob et al.   Frontiers in Microbiology

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

(2019) Maik Luu et al.   Nature Communications

Microbiome control of innate reactivity

(2019) Feidi Chen et al.   CURRENT OPINION IN IMMUNOLOGY

Microbes, metabolites, and the gut–lung axis

(2019) Anh Thu Dang et al.   Mucosal Immunology

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

(2019) Jason Lloyd-Price et al.   NATURE

The Innate Part of the Adaptive Immune System

(2019) Sophie Hillion et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

AhR Activation Leads to Massive Mobilization of Myeloid-Derived Suppressor Cells with Immunosuppressive Activity through Regulation of CXCR2 and MicroRNA miR-150-5p and miR-543-3p That Target Anti-Inflammatory Genes

(2019) Wurood Hantoosh Neamah et al.   JOURNAL OF IMMUNOLOGY

Diet-Microbe-Host Interactions That Affect Gut Mucosal Integrity and Infection Resistance

(2019) Andrew J. Forgie et al.   Frontiers in Immunology

Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity

(2019) Eunyoung Chun et al.   IMMUNITY

Understanding immune–microbiota interactions in the intestine

(2019) Philip P. Ahern et al.   IMMUNOLOGY

Potential Role of Gut Microbiota in Induction and Regulation of Innate Immune Memory

(2019) Shikha Negi et al.   Frontiers in Immunology

The importance of the microbiome in pediatrics and pediatric infectious diseases

(2018) Thaidra Gaufin et al.   CURRENT OPINION IN PEDIATRICS

Dietary Fiber Confers Protection against Flu by Shaping Ly6c − Patrolling Monocyte Hematopoiesis and CD8 + T Cell Metabolism

(2018) Aurélien Trompette et al.   IMMUNITY

The neonatal window of opportunity—early priming for life

(2018) Harald Renz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Intestinal microbiota in infants at high risk for allergy: Effects of prebiotics and role in eczema development

(2018) Harm Wopereis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Epigenetics of T cell aging

(2018) Jörg J. Goronzy et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Dietary Fiber Pectin Directly Blocks Toll-Like Receptor 2–1 and Prevents Doxorubicin-Induced Ileitis

(2018) Neha M. Sahasrabudhe et al.   Frontiers in Immunology

Modulation of the gut microbiota to improve innate resistance

(2018) Pamela Schnupf et al.   CURRENT OPINION IN IMMUNOLOGY

Inflammaging: a new immune–metabolic viewpoint for age-related diseases

(2018) Claudio Franceschi et al.   Nature Reviews Endocrinology

Aspects of Gut Microbiota and Immune System Interactions in Infectious Diseases, Immunopathology, and Cancer

(2018) Veronica Lazar et al.   Frontiers in Immunology

Antibodies: The major participants in maternal-fetal interaction

(2018) Xin Yang et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

The role of the microbiota in infectious diseases

(2018) Josie Libertucci et al.   Nature Microbiology

Fight them or feed them: how the intestinal mucus layer manages the gut microbiota

(2018) Bjoern O Schroeder   Gastroenterology Report

Guide for Current Nutrigenetic, Nutrigenomic, and Nutriepigenetic Approaches for Precision Nutrition Involving the Prevention and Management of Chronic Diseases Associated with Obesity

(2017) Omar Ramos-Lopez et al.   Journal of Nutrigenetics and Nutrigenomics

Estimates of global, regional, and national morbidity, mortality, and aetiologies of diarrhoeal diseases: a systematic analysis for the Global Burden of Disease Study 2015

(2017) Christopher Troeger et al.   LANCET INFECTIOUS DISEASES

A randomized synbiotic trial to prevent sepsis among infants in rural India

(2017) Pinaki Panigrahi et al.   NATURE

Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

(2017) Glenn R. Gibson et al.   Nature Reviews Gastroenterology & Hepatology

Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women

(2017) Nichole R. Klatt et al.   SCIENCE

Role of bioactive lipofishins in prevention of inflammation and colon cancer

(2017) Valter R.M. Lombardi et al.   SEMINARS IN CANCER BIOLOGY

Effect of Probiotics and Prebiotics on Immune Response to Influenza Vaccination in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

(2017) Wei-Te Lei et al.   Nutrients

Toward a Personalized Approach in Prebiotics Research

(2017) Moul Dey   Nutrients

Protective Microbiota: From Localized to Long-Reaching Co-Immunity

(2017) Lynn Chiu et al.   Frontiers in Immunology

The Intestinal Microbiome in Infectious Diseases: The Clinical Relevance of a Rapidly Emerging Field

(2017) Vanessa C Harris et al.   Open Forum Infectious Diseases

Defensins, lectins, mucins, and secretory immunoglobulin A: microbe-binding biomolecules that contribute to mucosal immunity in the human gut

(2016) Phoom Chairatana et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Gut–lung axis: The microbial contributions and clinical implications

(2016) Yang He et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Significant Correlation Between the Infant Gut Microbiome and Rotavirus Vaccine Response in Rural Ghana

(2016) Vanessa C. Harris et al.   JOURNAL OF INFECTIOUS DISEASES

Microbiota—myeloid cell crosstalk beyond the gut

(2016) Sayeh Gorjifard et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The microbiota in adaptive immune homeostasis and disease

(2016) Kenya Honda et al.   NATURE

The microbiome and innate immunity

(2016) Christoph A. Thaiss et al.   NATURE

Emerging pathogenic links between microbiota and the gut–lung axis

(2016) Kurtis F. Budden et al.   NATURE REVIEWS MICROBIOLOGY

Aging, inflammation, immunity and periodontal disease

(2016) Jeffrey L. Ebersole et al.   PERIODONTOLOGY 2000

Ageing alters the impact of nutrition on immune function

(2016) Parveen Yaqoob   PROCEEDINGS OF THE NUTRITION SOCIETY

Intestinal microbiome is related to lifetime antibiotic use in Finnish pre-school children

(2016) Katri Korpela et al.   Nature Communications

Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors

(2015) Talibah U. Metcalf et al.   AGING CELL

Effect of Lactobacillus paracasei subsp. paracasei, L. casei 431 on immune response to influenza vaccination and upper respiratory tract infections in healthy adult volunteers: a randomized, double-blind, placebo-controlled, parallel-group study

(2015) Lillian Jespersen et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Personalized Nutrition by Prediction of Glycemic Responses

(2015) David Zeevi et al.   CELL

MyD88 Signaling in T Cells Directs IgA-Mediated Control of the Microbiota to Promote Health

(2015) Jason L. Kubinak et al.   Cell Host & Microbe

Normalization of Host Intestinal Mucus Layers Requires Long-Term Microbial Colonization

(2015) Malin E.V. Johansson et al.   Cell Host & Microbe

The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia

(2015) Tim J Schuijt et al.   GUT

Th17 Cells as Potential Probiotic Therapeutic Targets in Inflammatory Bowel Diseases

(2015) Eddy Owaga et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Paradoxical changes in innate immunity in aging: recent progress and new directions

(2015) Ruth R. Montgomery et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Arabinoxylan activates Dectin-1 and modulates particulate β-glucan-induced Dectin-1 activation

(2015) Neha M. Sahasrabudhe et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Resistant starches differentially stimulate Toll-like receptors and attenuate proinflammatory cytokines in dendritic cells by modulation of intestinal epithelial cells

(2015) Miriam Bermudez-Brito et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Direct Regulation of TLR5 Expression by Caveolin-1

(2015)   MOLECULES AND CELLS

Early infancy microbial and metabolic alterations affect risk of childhood asthma

(2015) Marie-Claire Arrieta et al.   Science Translational Medicine

Effectiveness of probiotics on the duration of illness in healthy children and adults who develop common acute respiratory infectious conditions: a systematic review and meta-analysis

(2014) Sarah King et al.   BRITISH JOURNAL OF NUTRITION

Gut Microbiota Promote Hematopoiesis to Control Bacterial Infection

(2014) Arya Khosravi et al.   Cell Host & Microbe

Lack of microbiota reduces innate responses and enhances adaptive immunity againstListeria monocytogenesinfection

(2014) Hans-Willi Mittrücker et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Role of the Intestinal Microbiota in Resistance to Colonization by Clostridium difficile

(2014) Robert A. Britton et al.   GASTROENTEROLOGY

Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases

(2014) C. Franceschi et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Rice Bran Feruloylated Oligosaccharides Activate Dendritic Cells via Toll-Like Receptor 2 and 4 Signaling

(2014) Chi Lin et al.   MOLECULES

Commensal Gram-positive bacteria initiates colitis by inducing monocyte/macrophage mobilization

(2014) Y Nakanishi et al.   Mucosal Immunology

The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic

(2014) Colin Hill et al.   Nature Reviews Gastroenterology & Hepatology

The first thousand days - intestinal microbiology of early life: establishing a symbiosis

(2014) Harm Wopereis et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Correction: Through Ageing, and Beyond: Gut Microbiota and Inflammatory Status in Seniors and Centenarians

(2014) Elena Biagi et al.   PLoS One

Bacterial Bile Metabolising Gene Abundance in Crohn's, Ulcerative Colitis and Type 2 Diabetes Metagenomes

(2014) Alain Labbé et al.   PLoS One

Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection

(2013) Josué Pérez-Santiago et al.   AIDS

Probiotic supplementation for respiratory and gastrointestinal illness symptoms in healthy physically active individuals

(2013) Nicholas P. West et al.   CLINICAL NUTRITION

TLRs control hematopoiesis during infection

(2013) Alberto Yáñez et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Th17/Treg balance is disturbed during aging

(2013) Vanessa Schmitt et al.   EXPERIMENTAL GERONTOLOGY

The role of pattern recognition receptors in intestinal inflammation

(2013) M Fukata et al.   Mucosal Immunology

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

A comprehensive summary of LL-37, the factotum human cathelicidin peptide

(2012) Dieter Vandamme et al.   CELLULAR IMMUNOLOGY

Normal ageing is associated with an increase in Th2 cells, MCP-1 (CCL1) and RANTES (CCL5), with differences in sCD40L and PDGF-AA between sexes

(2012) A. S. Mansfield et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma

(2012) Shannon L Russell et al.   EMBO REPORTS

Intestinal colonization resistance

(2012) Trevor D. Lawley et al.   IMMUNOLOGY

Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2 and antibacterial peptides

(2012) A L Frantz et al.   Mucosal Immunology

The Role of Prebiotics and Probiotics in Prevention and Treatment of Childhood Infectious Diseases

(2012) Stefan Weichert et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Ageing and gut microbes: Perspectives for health maintenance and longevity

(2012) Elena Biagi et al.   PHARMACOLOGICAL RESEARCH

Impact of immune-metabolic interactions on age-related thymic demise and T cell senescence

(2012) Vishwa Deep Dixit   SEMINARS IN IMMUNOLOGY

Ageing of the human metaorganism: the microbial counterpart

(2011) Elena Biagi et al.   AGE

Age-associated elevation in TLR5 leads to increased inflammatory responses in the elderly

(2011) Feng Qian et al.   AGING CELL

Transient TLR Activation Restores Inflammatory Response and Ability To Control Pulmonary Bacterial Infection in Germfree Mice

(2011) C. T. Fagundes et al.   JOURNAL OF IMMUNOLOGY

Microbiota regulates immune defense against respiratory tract influenza A virus infection

(2011) T. Ichinohe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Commensal Microflora Contribute to Host Defense Against Escherichia Coli Pneumonia Through Toll-Like Receptors

(2011) Lee-Wei Chen et al.   SHOCK

Adaptive immunity

(2010) Francisco A. Bonilla et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Age-Associated Decrease in TLR Function in Primary Human Dendritic Cells Predicts Influenza Vaccine Response

(2010) Alexander Panda et al.   JOURNAL OF IMMUNOLOGY

Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism

(2009) E. Slack et al.   SCIENCE

Specific probiotics in reducing the risk of acute infections in infancy – a randomised, double-blind, placebo-controlled study

(2008) Samuli Rautava et al.   BRITISH JOURNAL OF NUTRITION