Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2 and antibacterial peptides

Human TLRs and IL-1Rs in Host Defense: Natural Insights from Evolutionary, Epidemiological, and Clinical Genetics

(2011) Jean-Laurent Casanova et al.   Annual Review of Immunology

Toll-Like Receptor–Gut Microbiota Interactions: Perturb at Your Own Risk!

(2011) Frederic A. Carvalho et al.   Annual Review of Physiology

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

Roadblocks in the gut: barriers to enteric infection

(2011) Navkiran Gill et al.   CELLULAR MICROBIOLOGY

Immunoglobulin A

(2011) Andrew J. Macpherson et al.   CURRENT OPINION IN GASTROENTEROLOGY

The Commensal Microbiota and Enteropathogens in the Pathogenesis of Inflammatory Bowel Diseases

(2011) Benoit Chassaing et al.   GASTROENTEROLOGY

Regulation of the polymeric immunoglobulin receptor by the classical and alternative NF-κB pathways in intestinal epithelial cells

(2011) M E C Bruno et al.   Mucosal Immunology

Regulation of the polymeric immunoglobulin receptor and IgA transport: new advances in environmental factors that stimulate pIgR expression and its role in mucosal immunity

(2011) F-E Johansen et al.   Mucosal Immunology

Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut

(2011) N J Mantis et al.   Mucosal Immunology

Intestinal homeostasis and its breakdown in inflammatory bowel disease

(2011) Kevin J. Maloy et al.   NATURE

Genetics and pathogenesis of inflammatory bowel disease

(2011) Bernard Khor et al.   NATURE

   intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surface

(2011) A. S. Ismail et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Antibacterial Lectin RegIII  Promotes the Spatial Segregation of Microbiota and Host in the Intestine

(2011) S. Vaishnava et al.   SCIENCE

Keeping Bacteria at a Distance

(2011) M. E. V. Johansson et al.   SCIENCE

Enterobacteriaceae Act in Concert with the Gut Microbiota to Induce Spontaneous and Maternally Transmitted Colitis

(2010) Wendy S. Garrett et al.   Cell Host & Microbe

Epithelial-specific blockade of MyD88-dependent pathway causes spontaneous small intestinal inflammation

(2010) Jianfeng Gong et al.   CLINICAL IMMUNOLOGY

Heads up! How the intestinal epithelium safeguards mucosal barrier immunity through the inflammasome and beyond

(2010) Elke Cario   CURRENT OPINION IN GASTROENTEROLOGY

Genes and Environment: How Will Our Concepts on the Pathophysiology of IBD Develop in the Future?

(2010) Arthur Kaser et al.   DIGESTIVE DISEASES

MyD88 Signaling in the Intestine: Dr Jekyll and Mr Hyde?

(2010) Christian Jobin   GASTROENTEROLOGY

Pathogenic and Protective Roles of MyD88 in Leukocytes and Epithelial Cells in Mouse Models of Inflammatory Bowel Disease

(2010) Mark J. Asquith et al.   GASTROENTEROLOGY

Secretory IgA: Arresting Microbial Pathogens at Epithelial Borders

(2010) Nicholas J. Mantis et al.   IMMUNOLOGICAL INVESTIGATIONS

Regulation of the Polymeric Immunoglobulin Receptor in Intestinal Epithelial Cells byEnterobacteriaceae: Implications for Mucosal Homeostasis

(2010) Maria E. C. Bruno et al.   IMMUNOLOGICAL INVESTIGATIONS

Toll-like receptors in inflammatory bowel diseases: A decade later

(2010) Elke Cario   INFLAMMATORY BOWEL DISEASES

UniFrac: an effective distance metric for microbial community comparison

(2010) Catherine Lozupone et al.   ISME Journal

Epithelial Myosin Light Chain Kinase Activation Induces Mucosal Interleukin-13 Expression to Alter Tight Junction Ion Selectivity

(2010) Christopher R. Weber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands

(2010) K. Brandl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Commensal bacteria, traditional and opportunistic pathogens, dysbiosis and bacterial killing in inflammatory bowel diseases

(2009) Christopher D Packey et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Joint Extraintestinal Manifestations in Ulcerative Colitis

(2009) A.E. Dorofeyev et al.   DIGESTIVE DISEASES

Both TRIF- and MyD88-Dependent Signaling Contribute to Host Defense against Pulmonary Klebsiella Infection

(2009) S. Cai et al.   JOURNAL OF IMMUNOLOGY

Comparisons of Subgingival Microbial Profiles of Refractory Periodontitis, Severe Periodontitis, and Periodontal Health Using the Human Oral Microbe Identification Microarray

(2009) Ana Paula V. Colombo et al.   JOURNAL OF PERIODONTOLOGY

Is there a role for defensins in IBD?

(2008) Jan Wehkamp et al.   INFLAMMATORY BOWEL DISEASES

Clinical use of E. coli Nissle 1917 in inflammatory bowel disease

(2008) Michael Schultz   INFLAMMATORY BOWEL DISEASES

Suppression of experimental colitis in mice by CD11c+ dendritic cells

(2008) Joseph E. Qualls et al.   INFLAMMATORY BOWEL DISEASES

Intestinal TM7 bacterial phylogenies in active inflammatory bowel disease

(2008) T. Kuehbacher et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Host and microbiota factors that control Klebsiella pneumoniae mucosal colonization in mice

(2008) Helen Y. Lau et al.   MICROBES AND INFECTION

Signature biomarkers in Crohn's disease: toward a molecular classification

(2008) R Arsenescu et al.   Mucosal Immunology

Mucins in the mucosal barrier to infection

(2008) S K Linden et al.   Mucosal Immunology

Direct multiplexed measurement of gene expression with color-coded probe pairs

(2008) Gary K Geiss et al.   NATURE BIOTECHNOLOGY

Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

(2008) H. von Bernuth et al.   SCIENCE