Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast

The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb

(2020) Ying Zhang et al.   Nature Communications

Early Scanning of Nascent Polypeptides inside the Ribosomal Tunnel by NAC

(2019) Martin Gamerdinger et al.   MOLECULAR CELL

The Ways of Tails: the GET Pathway and more

(2019) Nica Borgese et al.   PROTEIN JOURNAL

Sequential activation of human signal recognition particle by the ribosome and signal sequence drives efficient protein targeting

(2018) Jae Ho Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A structural perspective on tail-anchored protein biogenesis by the GET pathway

(2018) Agnieszka Mateja et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

RNA helicases mediate structural transitions and compositional changes in pre-ribosomal complexes

(2018) Lukas Brüning et al.   Nature Communications

Targeting and translocation of proteins to the endoplasmic reticulum at a glance

(2017) Naama Aviram et al.   JOURNAL OF CELL SCIENCE

Signal recognition particle binds to translating ribosomes before emergence of a signal anchor sequence

(2017) Evan Mercier et al.   NUCLEIC ACIDS RESEARCH

Mechanistic basis for a molecular triage reaction

(2017) Sichen Shao et al.   SCIENCE

On the road to nowhere: cross-talk between post-translational protein targeting and cytosolic quality control

(2016) J. Casson et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Cotranslational Intersection between the SRP and GET Targeting Pathways to the Endoplasmic Reticulum of Saccharomyces cerevisiae

(2016) Ying Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain

(2016) Andrea Gumiero et al.   Nature Communications

Analysis of the interplay of protein biogenesis factors at the ribosome exit site reveals new role for NAC

(2015) Yvonne Nyathi et al.   JOURNAL OF CELL BIOLOGY

Structures of the scanning and engaged states of the mammalian SRP-ribosome complex

(2015) Rebecca M Voorhees et al.   eLife

Structure of the Mammalian Ribosome-Sec61 Complex to 3.4 Å Resolution

(2014) Rebecca M. Voorhees et al.   CELL

A new system for naming ribosomal proteins

(2014) Nenad Ban et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Transcriptome Maps of mRNP Biogenesis Factors Define Pre-mRNA Recognition

(2014) Carlo Baejen et al.   MOLECULAR CELL

Cytosolic Quality Control of Mislocalized Proteins Requires RNF126 Recruitment to Bag6

(2014) Monica C. Rodrigo-Brenni et al.   MOLECULAR CELL

Secondary Structures of rRNAs from All Three Domains of Life

(2014) Anton S. Petrov et al.   PLoS One

Bag6 complex contains a minimal tail-anchor–targeting module and a mock BAG domain

(2014) Jee-Young Mock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A pre-ribosomal RNA interaction network involving snoRNAs and the Rok1 helicase

(2014) Roman Martin et al.   RNA

Co-translational targeting and translocation of proteins to the endoplasmic reticulum

(2013) Yvonne Nyathi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Interaction of Nascent Chains with the Ribosomal Tunnel Proteins Rpl4, Rpl17, and Rpl39 ofSaccharomyces cerevisiae

(2013) Ying Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Get5 Carboxyl-terminal Domain Is a Novel Dimerization Motif That Tethers an Extended Get4/Get5 Complex

(2012) Justin W. Chartron et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ribosome-Associated Complex and Ssb Are Required for Translational Repression Induced by Polylysine Segments within Nascent Chains

(2012) M. Chiabudini et al.   MOLECULAR AND CELLULAR BIOLOGY

NAC functions as a modulator of SRP during the early steps of protein targeting to the endoplasmic reticulum

(2012) Ying Zhang et al.   MOLECULAR BIOLOGY OF THE CELL

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Dynamic switch of the signal recognition particle from scanning to targeting

(2012) Wolf Holtkamp et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface

(2012) Justin W. Chartron et al.   Cell Reports

Membrane Protein Insertion at the Endoplasmic Reticulum

(2011) Sichen Shao et al.   Annual Review of Cell and Developmental Biology

Cooperative and independent activities of Sgt2 and Get5 in the targeting of tail-anchored proteins

(2011) Christian Kohl et al.   BIOLOGICAL CHEMISTRY

A Structural Model of the Sgt2 Protein and Its Interactions with Chaperones and the Get4/Get5 Complex

(2011) Justin W. Chartron et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Ubiquitin Ligase-Associated Chaperone Holdase Maintains Polypeptides in Soluble States for Proteasome Degradation

(2011) Qiuyan Wang et al.   MOLECULAR CELL

Tail-anchored membrane protein insertion into the endoplasmic reticulum

(2011) Ramanujan S. Hegde et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Saccharomyces Genome Database: the genomics resource of budding yeast

(2011) J. M. Cherry et al.   NUCLEIC ACIDS RESEARCH

The Structure of the Eukaryotic Ribosome at 3.0 A Resolution

(2011) A. Ben-Shem et al.   SCIENCE

Optimization of parameters for coverage of low molecular weight proteins

(2010) Stephan A. Müller et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Evolutionary Gain of Function for the ER Membrane Protein Sec62 from Yeast to Humans

(2010) Linda Müller et al.   MOLECULAR BIOLOGY OF THE CELL

A Chaperone Cascade Sorts Proteins for Posttranslational Membrane Insertion into the Endoplasmic Reticulum

(2010) Fei Wang et al.   MOLECULAR CELL

A ribosome-associating factor chaperones tail-anchored membrane proteins

(2010) Malaiyalam Mariappan et al.   NATURE

Structural characterization of the Get4/Get5 complex and its interaction with Get3

(2010) J. W. Chartron et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A signal-anchor sequence stimulates signal recognition particle binding to ribosomes from inside the exit tunnel

(2009) U. Berndt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome

(2009) T. Becker et al.   SCIENCE

Comprehensive Characterization of Genes Required for Protein Folding in the Endoplasmic Reticulum

(2009) M. C. Jonikas et al.   SCIENCE

The GET Complex Mediates Insertion of Tail-Anchored Proteins into the ER Membrane

(2008) Maya Schuldiner et al.   CELL

Precise measurement of diffusion by multi-color dual-focus fluorescence correlation spectroscopy

(2008) C. B. Müller et al.   EPL

Distinct targeting pathways for the membrane insertion of tail-anchored (TA) proteins

(2008) V. Favaloro et al.   JOURNAL OF CELL SCIENCE