Dynamic switch of the signal recognition particle from scanning to targeting

Lipids Trigger a Conformational Switch That Regulates Signal Recognition Particle (SRP)-mediated Protein Targeting

(2011) Goran Stjepanovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Site-Specific Fluorescent Labeling of Nascent Proteins on the Translating Ribosome

(2011) Ishu Saraogi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Signal sequence–independent SRP-SR complex formation at the membrane suggests an alternative targeting pathway within the SRP cycle

(2011) David Braig et al.   MOLECULAR BIOLOGY OF THE CELL

Structural basis of signal-sequence recognition by the signal recognition particle

(2011) Tobias Hainzl et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Synergistic actions between the SRP RNA and translating ribosome allow efficient delivery of the correct cargos during cotranslational protein targeting

(2011) K. Shen et al.   RNA

SecM-Stalled Ribosomes Adopt an Altered Geometry at the Peptidyl Transferase Center

(2011) Shashi Bhushan et al.   PLOS BIOLOGY

Early targeting events during membrane protein biogenesis in Escherichia coli

(2010) Eitan Bibi   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Recognition of a signal peptide by the signal recognition particle

(2010) Claudia Y. Janda et al.   NATURE

Cryo-EM structure of the E. coli translating ribosome in complex with SRP and its receptor

(2010) Leandro F Estrozi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Sequential Checkpoints Govern Substrate Selection During Cotranslational Protein Targeting

(2010) X. Zhang et al.   SCIENCE

Protein targeting by the signal recognition particle

(2009) Przemyslaw Grudnik et al.   BIOLOGICAL CHEMISTRY

Predominant membrane localization is an essential feature of the bacterial signal recognition particle receptor

(2009) Miryana Mircheva et al.   BMC BIOLOGY

Multiple conformational switches in a GTPase complex control co-translational protein targeting

(2009) Xin Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signal Sequences Activate the Catalytic Switch of SRP RNA

(2009) N. Bradshaw et al.   SCIENCE

Demonstration of a Multistep Mechanism for Assembly of the SRP·SRP Receptor Complex: Implications for the Catalytic Role of SRP RNA

(2008) Xin Zhang et al.   JOURNAL OF MOLECULAR BIOLOGY

Signal sequence–independent membrane targeting of ribosomes containing short nascent peptides within the exit tunnel

(2008) Thomas Bornemann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Conformation of the signal recognition particle in ribosomal targeting complexes

(2008) I. A. Buskiewicz et al.   RNA