Development of Spike Receptor-Binding Domain Nanoparticles as a Vaccine Candidate against SARS-CoV-2 Infection in Ferrets

Dose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity

(2021) Kathryn A. Ryan et al.   Nature Communications

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China

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A new coronavirus associated with human respiratory disease in China

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A Novel Coronavirus from Patients with Pneumonia in China, 2019

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Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan

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Potential association between COVID-19 mortality and health-care resource availability

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The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

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Infection and Rapid Transmission of SARS-CoV-2 in Ferrets

(2020) Young-Il Kim et al.   Cell Host & Microbe

Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2

(2020) Jianzhong Shi et al.   SCIENCE

Antiviral Efficacies of FDA-Approved Drugs against SARS-CoV-2 Infection in Ferrets

(2020) Su-Jin Park et al.   mBio

Recent Progress on the Versatility of Virus-Like Particles

(2020) Ciying Qian et al.   Vaccines

Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike

(2020) Lihong Liu et al.   NATURE

Distinct conformational states of SARS-CoV-2 spike protein

(2020) Yongfei Cai et al.   SCIENCE

Self-assembling influenza nanoparticle vaccines drive extended germinal center activity and memory B cell maturation

(2020) Hannah G. Kelly et al.   JCI Insight

Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology

(2020) Luca Piccoli et al.   CELL

Recovered COVID-19 patients with recurrent viral RNA exhibit lower levels of anti-RBD antibodies

(2020) Bingfeng Liu et al.   Cellular & Molecular Immunology

Asymptomatic Reinfection in 2 Healthcare Workers From India With Genetically Distinct Severe Acute Respiratory Syndrome Coronavirus 2

(2020) Vivek Gupta et al.   CLINICAL INFECTIOUS DISEASES

Coronavirus Disease 2019 (COVID-19) Re-infection by a Phylogenetically Distinct Severe Acute Respiratory Syndrome Coronavirus 2 Strain Confirmed by Whole Genome Sequencing

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Long-term Health Consequences of COVID-19

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Safety and Immunogenicity of the Ad26.RSV.preF Investigational Vaccine Coadministered With an Influenza Vaccine in Older Adults

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Genomic evidence for reinfection with SARS-CoV-2: a case study

(2020) Richard L Tillett et al.   LANCET INFECTIOUS DISEASES

Long-term consequences of COVID-19: research needs

(2020) Dana Yelin et al.   LANCET INFECTIOUS DISEASES

Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates

(2020) Edward E. Walsh et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase 1–2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine

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An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain

(2020) Nicholas C. Wu et al.   Cell Reports

Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity

(2020) Erik Volz et al.   CELL

Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine

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Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus

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Superior immune responses induced by intranasal immunization with recombinant adenovirus-based vaccine expressing full-length Spike protein of Middle East respiratory syndrome coronavirus

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Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses

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Investigating Viral Interference Between Influenza A Virus and Human Respiratory Syncytial Virus in a Ferret Model of Infection

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Chaperna-Mediated Assembly of Ferritin-Based Middle East Respiratory Syndrome-Coronavirus Nanoparticles

(2018) Young-Seok Kim et al.   Frontiers in Immunology

Virus-like particle vaccines: immunology and formulation for clinical translation

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Pathogenesis, humoral immune responses and transmission between co-housed animals in a ferret model of human RSV infection.

(2017) Kok Fei Chan et al.   JOURNAL OF VIROLOGY

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen

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Immune Response of A Novel ATR-AP205-001 Conjugate Anti-hypertensive Vaccine

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Immunogenicity and HPV infection after one, two, and three doses of quadrivalent HPV vaccine in girls in India: a multicentre prospective cohort study

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High-Density Array of Well-Ordered HIV-1 Spikes on Synthetic Liposomal Nanoparticles Efficiently Activate B Cells

(2016) Jidnyasa Ingale et al.   Cell Reports

Rational Design of an Epstein-Barr Virus Vaccine Targeting the Receptor-Binding Site

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Ferritin family proteins and their use in bionanotechnology

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Ferret models of viral pathogenesis

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Evaluation of oseltamivir prophylaxis regimens for reducing influenza virus infection, transmission and disease severity in a ferret model of household contact

(2014) Ding Yuan Oh et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The C-Terminal Regions Have an Important Role in the Activity of the Ferroxidase Center and the Stability of Chlorobium tepidum Ferritin

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Intranasal vaccination with recombinant receptor-binding domain of MERS-CoV spike protein induces much stronger local mucosal immune responses than subcutaneous immunization: Implication for designing novel mucosal MERS vaccines

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Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies

(2013) Masaru Kanekiyo et al.   NATURE

Protective immune responses in mice induced by intramuscular and intranasal immunization with a Mycoplasma pneumoniae P1C DNA vaccine

(2012) Cuiming Zhu et al.   CANADIAN JOURNAL OF MICROBIOLOGY

Innate Immunity Mediates Follicular Transport of Particulate but Not Soluble Protein Antigen

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Nanoparticle-based adjuvant for enhanced protective efficacy of DNA vaccine Ag85A-ESAT-6-IL-21 against Mycobacterium tuberculosis infection

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Lack of Innate Interferon Responses during SARS Coronavirus Infection in a Vaccination and Reinfection Ferret Model

(2012) Mark J. Cameron et al.   PLoS One

Receptor-binding domains of spike proteins of emerging or re-emerging viruses as targets for development of antiviral vaccines

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Effects of Different Adjuvants in the Context of Intramuscular and Intranasal Routes on Humoral and Cellular Immune Responses Induced by Detergent-Split A/H3N2 Influenza Vaccines in Mice

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Virus-like particles in vaccine development

(2010) António Roldão et al.   Expert Review of Vaccines

The Crystal Structure of Ferritin from Helicobacter pylori Reveals Unusual Conformational Changes for Iron Uptake

(2009) Ki Joon Cho et al.   JOURNAL OF MOLECULAR BIOLOGY

The SARS-CoV ferret model in an infection–challenge study

(2008) Yong-Kyu Chu et al.   VIROLOGY