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Title
Role of TSC1 in physiology and diseases
Authors
Keywords
-
Journal
MOLECULAR AND CELLULAR BIOCHEMISTRY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-02-12
DOI
10.1007/s11010-021-04088-3
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Note: Only part of the references are listed.- MicroRNA‐92b‐3p is a prognostic oncomiR that targets TSC1 in clear cell renal cell carcinoma
- (2020) Cong Wang et al. CANCER SCIENCE
- miR-20b and miR-451a Are Involved in Gastric Carcinogenesis through the PI3K/AKT/mTOR Signaling Pathway: Data from Gastric Cancer Patients, Cell Lines and Ins-Gas Mouse Model
- (2020) Greta Streleckiene et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Long non-coding RNA OIP5-AS1 suppresses multiple myeloma progression by sponging miR-27a-3p to activate TSC1 expression
- (2020) Yong Wang et al. Cancer Cell International
- Gut epithelial TSC1/mTOR controls RIPK3-dependent necroptosis in intestinal inflammation and cancer
- (2020) Yadong Xie et al. JOURNAL OF CLINICAL INVESTIGATION
- miR-301a suppression within fibroblasts limits the progression of fibrosis through the TSC1/mTOR pathway
- (2020) Jiexuan Wang et al. Molecular Therapy-Nucleic Acids
- miR‐196b‐5p controls adipocyte differentiation and lipogenesis through regulating mTORC1 and TGF‐β signaling
- (2020) Yaru Shi et al. FASEB JOURNAL
- Tsc1 Regulates the Proliferation Capacity of Bone-Marrow Derived Mesenchymal Stem Cells
- (2020) Maria V. Guijarro et al. Cells
- The Mitotic Cancer Target Polo-Like Kinase 1: Oncogene or Tumor Suppressor?
- (2019) Guillermo de Cárcer Genes
- microRNA 92b-3p regulates primordial follicle assembly by targeting TSC1 in neonatal mouse ovaries
- (2019) Tingting Li et al. CELL CYCLE
- AKT as a Therapeutic Target for Cancer
- (2019) Mengqiu Song et al. CANCER RESEARCH
- Loss of FOXP3 and TSC1 Accelerates Prostate Cancer Progression through Synergistic Transcriptional and Posttranslational Regulation of c-MYC
- (2019) Lianpin Wu et al. CANCER RESEARCH
- Osteocyte TSC1 promotes sclerostin secretion to restrain osteogenesis in mice
- (2019) Wen Liu et al. Open Biology
- Inactivation of TSC1 promotes epithelial-mesenchymal transition of renal tubular epithelial cells in mouse diabetic nephropathy
- (2019) Qian Lu et al. ACTA PHARMACOLOGICA SINICA
- In vitro Cell Migration, Invasion, and Adhesion Assays: From Cell Imaging to Data Analysis
- (2019) Jordi Pijuan et al. Frontiers in Cell and Developmental Biology
- TSC1/mTOR-controlled metabolic–epigenetic cross talk underpins DC control of CD8+ T-cell homeostasis
- (2019) Lei Shi et al. PLOS BIOLOGY
- 5-Aza-2′-deoxycytidine increases hypoxia tolerance-dependent autophagy in mouse neuronal cells by initiating the TSC1/mTOR pathway
- (2019) Ruifang Qi et al. BIOMEDICINE & PHARMACOTHERAPY
- Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity
- (2019) Mark R. Woodford et al. Oncotarget
- FTO is involved in Alzheimer's disease by targeting TSC1-mTOR-Tau signaling
- (2018) Huajie Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Plk1-Mediated Phosphorylation of TSC1 Enhances the Efficacy of Rapamycin
- (2018) Zhiguo Li et al. CANCER RESEARCH
- TSC1 regulates osteoclast podosome organization and bone resorption through mTORC1 and Rac1/Cdc42
- (2018) Song Xu et al. CELL DEATH AND DIFFERENTIATION
- TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms
- (2018) Thomas Rosengren et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Tsc1-dependent transcriptional programming of dendritic cell homeostasis and function
- (2018) Yuechen Luo et al. EXPERIMENTAL CELL RESEARCH
- Tsc1 Regulates the Balance Between Osteoblast and Adipocyte Differentiation Through Autophagy/Notch1/β-Catenin Cascade
- (2018) Han Kyoung Choi et al. JOURNAL OF BONE AND MINERAL RESEARCH
- A novel SOCS5/miR-18/miR-25 axis promotes tumorigenesis in liver cancer
- (2018) A Sanchez-Mejias et al. INTERNATIONAL JOURNAL OF CANCER
- IKBKE inhibits TSC1 to activate the mTOR/S6K pathway for oncogenic transformation
- (2018) Serkan İsmail GÖKTUNA TURKISH JOURNAL OF BIOLOGY
- miR-92b-3p-TSC1 axis is critical for mTOR signaling-mediated vascular smooth muscle cell proliferation induced by hypoxia
- (2018) Jihui Lee et al. CELL DEATH AND DIFFERENTIATION
- MiR-126-3p promotes the cell proliferation and inhibits the cell apoptosis by targeting TSC1 in the porcine granulosa cells
- (2018) Xiaolong Yuan et al. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
- MicroRNA-92a Drives Th1 Responses in the Experimental Autoimmune Encephalomyelitis
- (2018) Nahid Rezaei et al. INFLAMMATION
- Analysis of TSC1 mutation spectrum in mucosal melanoma
- (2017) Meng Ma et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Tsc1 expression by dendritic cells is required to preserve T-cell homeostasis and response
- (2017) Yuechen Luo et al. Cell Death & Disease
- microRNA-19a protects osteoblasts from dexamethasone via targeting TSC1
- (2017) Gang Liu et al. Oncotarget
- Downregulation of MicroRNA-193b-3p Promotes Autophagy and Cell Survival by Targeting TSC1/mTOR Signaling in NSC-34 Cells
- (2017) ChunYu Li et al. Frontiers in Molecular Neuroscience
- Moderate lifelong overexpression of tuberous sclerosis complex 1 (TSC1) improves health and survival in mice
- (2017) Hong-Mei Zhang et al. Scientific Reports
- Focal Adhesion–Independent Cell Migration
- (2016) Ewa K. Paluch et al. Annual Review of Cell and Developmental Biology
- Constitutive adipocyte mTORC1 activation enhances mitochondrial activity and reduces visceral adiposity in mice
- (2016) Juliana Magdalon et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Mutations in TSC1, TSC2, and MTOR Are Associated with Response to Rapalogs in Patients with Metastatic Renal Cell Carcinoma
- (2016) D. J. Kwiatkowski et al. CLINICAL CANCER RESEARCH
- TSC1/2 mutations define a molecular subset of HCC with aggressive behaviour and treatment implication
- (2016) Daniel W H Ho et al. GUT
- TSC1-mTOR signaling determines the differentiation of islet cells
- (2016) Li Ding et al. JOURNAL OF ENDOCRINOLOGY
- NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation
- (2016) Meixiang Yang et al. Nature Communications
- Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα and cell-cycle-driving proteins
- (2016) Zhenqi Qin et al. Scientific Reports
- Constitutive Activation of mTORC1 in Endothelial Cells Leads to the Development and Progression of Lymphangiosarcoma through VEGF Autocrine Signaling
- (2015) Shaogang Sun et al. CANCER CELL
- Targeted deletion of Tsc1 causes fatal cardiomyocyte hyperplasia independently of afterload
- (2015) Usamah S. Kayyali et al. CARDIOVASCULAR PATHOLOGY
- Tsc1 is a Critical Regulator of Macrophage Survival and Function
- (2015) Chunmin Fang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- TSC1 Activates TGF-β-Smad2/3 Signaling in Growth Arrest and Epithelial-to-Mesenchymal Transition
- (2015) Antje Thien et al. DEVELOPMENTAL CELL
- TSC1 Promotes B Cell Maturation but Is Dispensable for Germinal Center Formation
- (2015) Xinxin Ci et al. PLoS One
- miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway
- (2015) Ismael Riquelme et al. CELLULAR ONCOLOGY
- MicroRNA-451 regulates stemness of side population cells via PI3K/Akt/mTOR signaling pathway in multiple myeloma
- (2015) Juan Du et al. Oncotarget
- AKT3 promotes prostate cancer proliferation cells through regulation of Akt, B-Raf & TSC1/TSC2
- (2015) Hui-Ping Lin et al. Oncotarget
- Genetic Variations in STK11, PRKAA1, and TSC1 Associated with Prognosis for Patients with Colorectal Cancer
- (2014) Soo Jung Lee et al. ANNALS OF SURGICAL ONCOLOGY
- Cortical Tubers: Windows into Dysregulation of Epilepsy Risk and Synaptic Signaling Genes by MicroRNAs
- (2014) Alan A. Dombkowski et al. CEREBRAL CORTEX
- Tuberous Sclerosis Complex 1–Mechanistic Target of Rapamycin Complex 1 Signaling Determines Brown-to-White Adipocyte Phenotypic Switch
- (2014) Xinxin Xiang et al. DIABETES
- Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1
- (2014) Alessia Di Nardo et al. HUMAN MOLECULAR GENETICS
- Role of Tumor Suppressor TSC1 in Regulating Antigen-Specific Primary and Memory CD8 T Cell Responses to Bacterial Infection
- (2014) Sruti Krishna et al. INFECTION AND IMMUNITY
- MiR-451 is decreased in hypertrophic cardiomyopathy and regulates autophagy by targeting TSC1
- (2014) Lei Song et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions
- (2014) Jinhong Wu et al. JOURNAL OF CLINICAL INVESTIGATION
- Tuberous Sclerosis 1 Promotes Invariant NKT Cell Anergy and Inhibits Invariant NKT Cell-Mediated Antitumor Immunity
- (2014) J. Wu et al. JOURNAL OF IMMUNOLOGY
- Prognostic implication of TSC1 and mTOR expression in gastric carcinoma
- (2014) Sun-ju Byeon et al. JOURNAL OF SURGICAL ONCOLOGY
- Evidence that TSC2 acts as a transcription factor and binds to and represses the promoter of Epiregulin
- (2014) Shalmali Avinash Pradhan et al. NUCLEIC ACIDS RESEARCH
- Identification of Regions Critical for the Integrity of the TSC1-TSC2-TBC1D7 Complex
- (2014) Arthur Jorge Santiago Lima et al. PLoS One
- Mechanistic target of rapamycin complex 1 is critical for invariant natural killer T-cell development and effector function
- (2014) J. Shin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs
- (2014) S. Shrestha et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TSC1 controls macrophage polarization to prevent inflammatory disease
- (2014) Linnan Zhu et al. Nature Communications
- Neurogenin 3–Directed Cre Deletion of Tsc1 Gene Causes Pancreatic Acinar Carcinoma
- (2014) Li Ding et al. NEOPLASIA
- MTORC1 determines autophagy through ULK1 regulation in skeletal muscle
- (2013) Perrine Castets et al. Autophagy
- Hyperactivation of Mammalian Target of Rapamycin Complex 1 (mTORC1) Promotes Breast Cancer Progression through Enhancing Glucose Starvation-induced Autophagy and Akt Signaling
- (2013) Yongqiang Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TSC1 regulates the balance between effector and regulatory T cells
- (2013) Yoon Park et al. JOURNAL OF CLINICAL INVESTIGATION
- Acquired Cardiomyopathy Caused by Cardiac Tsc1 Deficiency
- (2013) Yi Chen et al. Journal of Genetics and Genomics
- Critical Role of the Tumor Suppressor Tuberous Sclerosis Complex 1 in Dendritic Cell Activation of CD4 T Cells by Promoting MHC Class II Expression via IRF4 and CIITA
- (2013) H. Pan et al. JOURNAL OF IMMUNOLOGY
- TSC1involvement in bladder cancer: diverse effects and therapeutic implications
- (2013) Yanan Guo et al. JOURNAL OF PATHOLOGY
- Platelet-Derived Growth Factor/Vascular Endothelial Growth Factor Receptor Inactivation by Sunitinib Results in Tsc1/Tsc2-Dependent Inhibition of TORC1
- (2013) T. A. Tran et al. MOLECULAR AND CELLULAR BIOLOGY
- Conditional deletion of Tsc1 in the female reproductive tract impedes normal oviductal and uterine function by enhancing mTORC1 signaling in mice
- (2013) T. Daikoku et al. MOLECULAR HUMAN REPRODUCTION
- Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy
- (2013) Michalis Papadakis et al. NATURE MEDICINE
- Specific Disruption of Tsc1 in Ovarian Granulosa Cells Promotes Ovulation and Causes Progressive Accumulation of Corpora Lutea
- (2013) Lin Huang et al. PLoS One
- TSC1 Controls Distribution of Actin Fibers through Its Effect on Function of Rho Family of Small GTPases and Regulates Cell Migration and Polarity
- (2013) Maki Ohsawa et al. PLoS One
- Tuberous sclerosis 1 (Tsc1)-dependent metabolic checkpoint controls development of dendritic cells
- (2013) Y. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of mast cell survival and function by tuberous sclerosis complex 1
- (2012) J. Shin et al. BLOOD
- The Role of Tuberous Sclerosis Complex 1 in Regulating Innate Immunity
- (2012) H. Pan et al. JOURNAL OF IMMUNOLOGY
- TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1
- (2012) Christian C. Dibble et al. MOLECULAR CELL
- TSC1/2 Signaling Complex Is Essential for Peripheral Naïve CD8+ T Cell Survival and Homeostasis in Mice
- (2012) Lianjun Zhang et al. PLoS One
- Hepatitis B Virus X Protein Upregulates mTOR Signaling through IKKβ to Increase Cell Proliferation and VEGF Production in Hepatocellular Carcinoma
- (2012) Chia-Jui Yen et al. PLoS One
- Tumor suppressor TSC1 is critical for T-cell anergy
- (2012) D.-L. Xie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme
- (2012) S.-S. Suh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chronic Activation of mTOR Complex 1 Is Sufficient to Cause Hepatocellular Carcinoma in Mice
- (2012) S. Menon et al. Science Signaling
- Deletion of Tuberous Sclerosis 1 in Somatic Cells of the Murine Reproductive Tract Causes Female Infertility
- (2011) Yoshihiro Tanaka et al. ENDOCRINOLOGY
- Regulation of T-cell survival and mitochondrial homeostasis by TSC1
- (2011) Thomas F. O'Brien et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Direct activation of mTOR in B lymphocytes confers impairment in B-cell maturation andloss of marginal zone B cells
- (2011) Sandrine Benhamron et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle
- (2011) J. Zhou et al. GENES & DEVELOPMENT
- Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin
- (2011) A. J. Malhowski et al. HUMAN MOLECULAR GENETICS
- The Tumor Suppressor Hamartin Enhances Dbl Protein Transforming Activity through Interaction with Ezrin
- (2011) Marzia Ognibene et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Tuberous Sclerosis Complex-Mammalian Target of Rapamycin Pathway Maintains the Quiescence and Survival of Naive T Cells
- (2011) Q. Wu et al. JOURNAL OF IMMUNOLOGY
- The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function
- (2011) Kai Yang et al. NATURE IMMUNOLOGY
- Polymorphic variants in TSC1 and TSC2 and their association with breast cancer phenotypes
- (2010) Madhura S. Mehta et al. BREAST CANCER RESEARCH AND TREATMENT
- Tuberous Sclerosis Complex 1: An Epithelial Tumor Suppressor Essential to Prevent Spontaneous Prostate Cancer in Aged Mice
- (2010) R. D. Kladney et al. CANCER RESEARCH
- The axis of mTOR-mitochondria-ROS and stemness of the hematopoietic stem cells
- (2010) Chong Chen et al. CELL CYCLE
- The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis
- (2010) Y J Kang et al. CELL DEATH AND DIFFERENTIATION
- FOXO3a Regulates Glycolysis via Transcriptional Control of Tumor Suppressor TSC1
- (2010) Shikha Khatri et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Critical roles for the TSC-mTOR pathway in β-cell function
- (2009) Hiroyuki Mori et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles
- (2009) D. Adhikari et al. HUMAN MOLECULAR GENETICS
- TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity
- (2009) M-C Liang et al. ONCOGENE
- The TSC1–TSC2 complex: a molecular switchboard controlling cell growth
- (2008) Jingxiang Huang et al. BIOCHEMICAL JOURNAL
- Involvement of TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinoma
- (2008) Sanjukta Chakraborty et al. BMC CANCER
- Genetics and Molecular Biology of Tuberous Sclerosis Complex
- (2008) Valerio Napolioni et al. CURRENT GENOMICS
- Zebrafish Tsc1 reveals functional interactions between the cilium and the TOR pathway
- (2008) Linda M. DiBella et al. HUMAN MOLECULAR GENETICS
- Bladder tumour-derived somatic TSC1 missense mutations cause loss of function via distinct mechanisms
- (2008) Louis S. Pymar et al. HUMAN MOLECULAR GENETICS
- The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway
- (2008) Tiffiney R. Hartman et al. HUMAN MOLECULAR GENETICS
- Loss of the Tuberous Sclerosis Complex Tumor Suppressors Triggers the Unfolded Protein Response to Regulate Insulin Signaling and Apoptosis
- (2008) Umut Ozcan et al. MOLECULAR CELL
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