Ruthenium-catalyzed C–H bond functionalization in cascade and one-pot transformations

Ruthenium‐Catalyzed Double C(sp2)‐H Functionalizations of Fumaramides with Alkynes for Divergent Synthesis of Pyridones and Naphthyridinediones

(2020) Zhi-Jian Han et al.   ChemCatChem

Ruthenium(II)-Catalyzed Double Annulation of Quinones: Step-Economical Access to Valuable Bioactive Compounds

(2020) Eufrânio N. da Silva Júnior et al.   CHEMISTRY-A EUROPEAN JOURNAL

Steering Site-Selectivity in Transition Metal-Catalyzed C-H Bond Functionalization: the Challenge of Benzanilides

(2020) Rafael Gramage-Doria   CHEMISTRY-A EUROPEAN JOURNAL

Achieving Site-Selectivity for C–H Activation Processes Based on Distance and Geometry: A Carpenter’s Approach

(2020) Guangrong Meng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt(III)-Catalyzed Redox-Neutral Coupling of Acrylamides with Activated Alkenes via C–H Bond Activation

(2020) Masilamani Jeganmohan et al.   SYNTHESIS-STUTTGART

Divergent Syntheses of Spiroindanones and 2-Substituted 1-Indanones by Ruthenium-Catalyzed Tandem Coupling and Cyclization of Aromatic Acids with α,ß-Unsaturated Ketones

(2019) Jia-Ni Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Recent Advances in C–H Bond Functionalization with Ruthenium-Based Catalysts

(2019) Keisham S. Singh   Catalysts

Biomass-Derived Solvents for Sustainable Transition Metal-Catalyzed C‒H Activation

(2019) Gandeepan Parthasarathy et al.   ACS Sustainable Chemistry & Engineering

Isomerizing Olefin Metathesis

(2019) Jacqueline Pollini et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent Advancements in Transition‐Metal‐Catalyzed One‐Pot Twofold Unsymmetrical Difunctionalization of Arenes

(2019) Anup Mandal et al.   Chemistry-An Asian Journal

Electrochemically Enabled Double C–H Activation of Amides: Chemoselective Synthesis of Polycyclic Isoquinolinones

(2019) Zi-Qiang Wang et al.   ORGANIC LETTERS

Ring-Opening Olefin Metathesis of Twisted Amides: Activation of Amide Bonds by C═C Cleavage

(2019) Qun Zhao et al.   ACS Catalysis

Advances in One-Pot Synthesis through Borrowing Hydrogen Catalysis

(2018) Avelino Corma et al.   CHEMICAL REVIEWS

Pd Metal Catalysts for Cross-Couplings and Related Reactions in the 21st Century: A Critical Review

(2018) Andrea Biffis et al.   CHEMICAL REVIEWS

Green and Sustainable Solvents in Chemical Processes

(2018) Coby J. Clarke et al.   CHEMICAL REVIEWS

Regioselective C−H Alkylation via Carboxylate-Directed Hydroarylation in Water

(2018) Guodong Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ruthenium-Mediated Distal C−H Activation

(2018) Farheen Fatima Khan et al.   Chemistry-An Asian Journal

Ruthenium(II)-Catalyzed C–H (Hetero)Arylation of Alkenylic 1,n-Diazines (n = 2, 3, and 4): Scope, Mechanism, and Application in Tandem Hydrogenations

(2018) Rafael Gramage-Doria et al.   JOURNAL OF ORGANIC CHEMISTRY

Ruthenium-Catalyzed Regioselective Alkenylation/Tandem Hydroamidative Cyclization of Unmasked Quinazolinones Using Terminal Alkynes

(2018) Amol B. Viveki et al.   JOURNAL OF ORGANIC CHEMISTRY

Ru(II)-Catalyzed Oxidative Heck-Type Olefination of Aromatic Carboxylic Acids with Styrenes through Carboxylate-Assisted C–H Bond Activation

(2018) Suman Dana et al.   ORGANIC LETTERS

An Orchestrated Unsymmetrical Annulation Episode of C(sp2)–H Bonds with Alkynes and Quinones: Access to Spiro-isoquinolones

(2018) Kallol Mukherjee et al.   ORGANIC LETTERS

Recent advances in C(sp 3 ) H bond carbonylation by first row transition metals

(2018) Nimmakuri Rajesh et al.   TETRAHEDRON LETTERS

Sequential meta-/ortho-C–H Functionalizations by One-Pot Ruthenium(II/III) Catalysis

(2018) Korkit Korvorapun et al.   ACS Catalysis

A comprehensive overview of directing groups applied in metal-catalysed C–H functionalisation chemistry

(2018) Carlo Sambiagio et al.   CHEMICAL SOCIETY REVIEWS

Mechanistic view of Ru-catalyzed C–H bond activation and functionalization: computational advances

(2018) Chunhui Shan et al.   CHEMICAL SOCIETY REVIEWS

Ruthenium(IV) Intermediates in C−H Activation/Annulation by Weak O-Coordination

(2018) Yu-Feng Liang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Sulfoximine-Assisted One-Pot Unsymmetrical Multiple Annulation of Arenes: A Combined Experimental and Computational Study

(2018) Koushik Ghosh et al.   JOURNAL OF ORGANIC CHEMISTRY

Recent advances in homogeneous borrowing hydrogen catalysis using earth-abundant first row transition metals

(2018) Benjamin G. Reed-Berendt et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

One-Pot Unsymmetrical {[4 + 2] and [4 + 2]} Double Annulations of o/o′-C–H Bonds of Arenes: Access to Unusual Pyranoisoquinolines

(2018) Majji Shankar et al.   ORGANIC LETTERS

Oxazolinyl-Assisted Ru(II)-Catalyzed C−H Functionalization Based on Carbene Migratory Insertion: A One-Pot Three-Component Cascade Cyclization

(2018) Gangam Srikanth Kumar et al.   ADVANCED SYNTHESIS & CATALYSIS

Game of Directors: Accessing Remote Meta- and Para-C--H Bonds With Covalently Attached Directing Groups

(2018) Aniruddha Dey et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

3d Transition Metals for C–H Activation

(2018) Parthasarathy Gandeepan et al.   CHEMICAL REVIEWS

Exceedingly Fast, Direct Access to Dihydroisoquinolino[1,2-b]quinazolinones through a Ruthenium(II)-Catalyzed Redox-Neutral C–H Allylation/Hydroamination Cascade

(2018) Gurupada Bairy et al.   ORGANIC LETTERS

Building molecular complexity through transition-metal-catalyzed oxidative annulations/cyclizations: Harnessing the utility of phenols, naphthols and 1,3-dicarbonyl compounds

(2018) Imtiaz Khan et al.   COORDINATION CHEMISTRY REVIEWS

Quinazoline-Directed C-H Bond Functionalization Catalyzed by Ruthenium(II) Carboxylate - Construction of Polyconjugated Aryl-Heteroaryl Systems

(2017) Bogdan Štefane et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Ruthenium-Catalyzed Oxidative Annulation and Hydroarylation of Chromene-3-carboxamides with Alkynes via Double C–H Functionalization

(2017) R. N. Prasad Tulichala et al.   JOURNAL OF ORGANIC CHEMISTRY

Ru-Catalysed synthesis of fused heterocycle-pyridinones and -pyrones

(2017) S. Ruiz et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Ruthenium(II)-Catalyzed Indolo[2,1-a]isoquinolines Synthesis by Tandem C–H Allylation and Oxidative Cyclization of 2-Phenylindoles with Allyl Carbonates

(2017) Ying-Qi Xia et al.   ORGANIC LETTERS

Ruthenium-Catalyzed meta-Carboxylation

(2017) Helen L. Barlow et al.   ORGANIC LETTERS

Traceless Directing-Group Strategy in the Ru-Catalyzed, Formal [3 + 3] Annulation of Anilines with Allyl Alcohols: A One-Pot, Domino Approach for the Synthesis of Quinolines

(2017) Gangam Srikanth Kumar et al.   ORGANIC LETTERS

Transformable Sulfoximine Assisted One-Pot Double Annulation of Vinylic C–H Bonds with Unactivated Alkynes

(2017) Majji Shankar et al.   ORGANIC LETTERS

Tandem Hydrosilylation/o-C–H Silylation of Arylalkynes Catalyzed by Ruthenium Bis(silyl) Aminophosphine Complexes

(2017) Takeo Kitano et al.   ORGANOMETALLICS

Highly chemoselective ruthenium(ii)-catalyzed direct arylation of cyclic and N,N-dialkyl benzamides with aryl silanes

(2017) Pradeep Nareddy et al.   Chemical Science

Ruthenium(II)-catalysed remote C–H alkylations as a versatile platform to meta-decorated arenes

(2017) Jie Li et al.   Nature Communications

Recent Developments in Ruthenium-Catalyzed C–H Arylation: Array of Mechanistic Manifolds

(2017) Pradeep Nareddy et al.   ACS Catalysis

One-Pot Directing Group Formation/C−H Bond FunctionalizationviaCopper(I) and Ruthenium(II) Catalysis

(2016) Christian Bruneau et al.   ADVANCED SYNTHESIS & CATALYSIS

Metal-Catalyzed Annulations through Activation and Cleavage of C−H Bonds

(2016) Moisés Gulías et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regioselective C−H Hydroarylation of Internal Alkynes with Arenecarboxylates: Carboxylates as Deciduous Directing Groups

(2016) Liangbin Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium-Catalyzed Hydroarylation and One-Pot Twofold Unsymmetrical C−H Functionalization of Arenes

(2016) Koushik Ghosh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium(II)-Catalyzed Decarboxylative C−H Activation: Versatile Routes tometa-Alkenylated Arenes

(2016) N. Y. Phani Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reaching the south: metal-catalyzed transformation of the aromatic para-position

(2016) Aniruddha Dey et al.   CHEMICAL COMMUNICATIONS

The medicinal chemist's toolbox for late stage functionalization of drug-like molecules

(2016) Tim Cernak et al.   CHEMICAL SOCIETY REVIEWS

Recent Advances in C–H Functionalization

(2016) Huw M. L. Davies et al.   JOURNAL OF ORGANIC CHEMISTRY

A decarboxylative approach for regioselective hydroarylation of alkynes

(2016) Jing Zhang et al.   Nature Chemistry

Palladium catalysed meta-C–H functionalization reactions

(2016) Aniruddha Dey et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Combining Ru-Catalyzed C–H Functionalization with Pd-Catalyzed Asymmetric Allylic Alkylation: Synthesis of 3-Allyl-3-aryl Oxindole Derivatives from Aryl α-Diazoamides

(2016) Kosuke Yamamoto et al.   ORGANIC LETTERS

Ruthenium(0)-Catalyzed C–H Arylation of Aromatic Imines under Neutral Conditions: Access to Biaryl Aldehydes

(2016) Feng Hu et al.   ORGANIC LETTERS

Ru-Catalyzed One-Pot Diannulation of Heteroaryls: Direct Access to π-Conjugated Polycyclic Amides

(2016) Majji Shankar et al.   ORGANIC LETTERS

Ruthenium-Catalyzed Oxidative Coupling of Primary Amines with Internal Alkynes through CH Bond Activation: Scope and Mechanistic Studies

(2015) Sara Ruiz et al.   CHEMISTRY-A EUROPEAN JOURNAL

Unprecedented Transformation of a Directing Group Generated In Situ and Its Application in the One-Pot Synthesis of 2-Alkenyl Benzonitriles

(2015) Ravi Kumar et al.   CHEMISTRY-A EUROPEAN JOURNAL

Acylation of (Hetero)Arenes through CH Activation with Aroyl Surrogates

(2015) Xiao-Feng Wu   CHEMISTRY-A EUROPEAN JOURNAL

Evolution of C–H Bond Functionalization from Methane to Methodology

(2015) John F. Hartwig   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent advances in the ruthenium-catalyzed hydroarylation of alkynes with aromatics: synthesis of trisubstituted alkenes

(2015) Rajendran Manikandan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Development of a One-Pot Tandem Reaction Combining Ruthenium-Catalyzed Alkene Metathesis and Enantioselective Enzymatic Oxidation To Produce Aryl Epoxides

(2015) Carl A. Denard et al.   ACS Catalysis

Transition metal-catalyzed C–H bond functionalizations by the use of diverse directing groups

(2015) Zhengkai Chen et al.   Organic Chemistry Frontiers

Weakly Coordinating Directing Groups for Ruthenium(II)- Catalyzed CH Activation

(2014) Suman De Sarkar et al.   ADVANCED SYNTHESIS & CATALYSIS

Ruthenium-Catalyzed Cascade CH Functionalization of Phenylacetophenones

(2014) Vaibhav P. Mehta et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

sp3C–H bond alkylation of ketones with alkenes via ruthenium(ii) catalysed dehydrogenation of alcohols

(2014) Bin Li et al.   CHEMICAL COMMUNICATIONS

Ruthenium-Catalyzed Cyclization of Aromatic Nitriles with Alkenes: Stereoselective Synthesis of (Z)-3-Methyleneisoindolin-1-ones

(2014) Mallu Chenna Reddy et al.   ORGANIC LETTERS

Pyrene-Based Mono- and Di-N-Heterocyclic Carbene Ligand Complexes of Ruthenium for the Preparation of Mixed Arylated/Alkylated Arylpyridines

(2014) Sergio Gonell et al.   ACS Catalysis

Ruthenium(ii)-catalyzed C–H activation/C–N bond formation via in situ generated iminophosphorane as the directing group: construction of annulated pyridin-2(1H)-ones

(2014) Rajesh K. Arigela et al.   RSC Advances

Carboxylate-Assisted Ruthenium-Catalyzed Alkyne Annulations by C–H/Het–H Bond Functionalizations

(2013) Lutz Ackermann   ACCOUNTS OF CHEMICAL RESEARCH

Ruthenium-Catalyzed Carbonylative CC Coupling in Water by Directed CH Bond Activation

(2013) Anis Tlili et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rh(iii)-catalyzed dehydrogenative alkylation of (hetero)arenes with allylic alcohols, allowing aldol condensation to indenes

(2013) Zhuangzhi Shi et al.   CHEMICAL COMMUNICATIONS

Ruthenium-catalyzed aerobic oxidative cyclization of aromatic and heteroaromatic nitriles with alkynes: a new route to isoquinolones

(2013) Mallu Chenna Reddy et al.   CHEMICAL COMMUNICATIONS

Primary Amines as Directing Groups in the Ru-Catalyzed Synthesis of Isoquinolines, Benzoisoquinolines, and Thienopyridines

(2013) Pedro Villuendas et al.   JOURNAL OF ORGANIC CHEMISTRY

C–H bond activation enables the rapid construction and late-stage diversification of functional molecules

(2013) Joanna Wencel-Delord et al.   Nature Chemistry

Palladium-Catalyzed Cross-Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize

(2012) Carin C. C. Johansson Seechurn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization

(2012) Percia Beatrice Arockiam et al.   CHEMICAL REVIEWS

Sequential Protocol for C(sp3)–H Carboxylation with CO2: Transition-Metal-Catalyzed Benzylic C–H Silylation and Fluoride-Mediated Carboxylation

(2012) Tsuyoshi Mita et al.   ORGANIC LETTERS

Short Synthesis of Alkyl-Substituted Acenes Using Carbonyl-Directed C–H and C–O Functionalization

(2012) Daiki Matsumura et al.   ORGANIC LETTERS

Ru(II)-Catalyzed C–H Bond Activation for the Synthesis of Substituted Isoquinolinium Salts from Benzaldehydes, Amines, and Alkynes

(2012) Kanniyappan Parthasarathy et al.   ORGANIC LETTERS

Ruthenium-Catalyzed Pyrrole Synthesis via Oxidative Annulation of Enamides and Alkynes

(2012) Bin Li et al.   ORGANIC LETTERS

Catalytic C–H bond arylation of aryl imines and oxazolines in water with ruthenium(II)-acetate catalyst

(2012) Bin Li et al.   TETRAHEDRON

Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions

(2011) Keary M. Engle et al.   ACCOUNTS OF CHEMICAL RESEARCH

Tandem Catalysis: Alcohol Oxidation and CC Bond Formation via CH Bond Activation

(2011) Marc-Olivier Simon et al.   ADVANCED SYNTHESIS & CATALYSIS

Magical Power of Transition Metals: Past, Present, and Future (Nobel Lecture)

(2011) Ei-ichi Negishi   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Oxidative Carbonylation Reactions: Organometallic Compounds (RM) or Hydrocarbons (RH) as Nucleophiles

(2011) Qiang Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cross-Coupling Reactions Of Organoboranes: An Easy Way To Construct CC Bonds (Nobel Lecture)

(2011) Akira Suzuki   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent developments in natural product synthesis using metal-catalysed C–H bond functionalisation

(2011) Lindsay McMurray et al.   CHEMICAL SOCIETY REVIEWS

Ruthenium-Catalyzed Regioselective Cyclization of Aromatic Ketones with Alkynes: An Efficient Route to Indenols and Benzofulvenes

(2011) Ravi Kiran Chinnagolla et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Carboxylate-Assisted Ruthenium-Catalyzed Direct Alkylations of Ketimines

(2011) Lutz Ackermann et al.   ORGANIC LETTERS

Sequential Catalysis for the Production of Sterically Hindered Amines: Ru(II)-Catalyzed C–H Bond Activation and Hydrosilylation of Imines

(2011) Bin Li et al.   ACS Catalysis

Metal-catalyzed direct alkylations of (hetero)arenes via C–H bond cleavages with unactivated alkyl halides

(2010) Lutz Ackermann   CHEMICAL COMMUNICATIONS

Ruthenium-Catalyzed Aromatic C−H Activation of Benzylic Alcohols via Remote Electronic Activation

(2010) Andrew J. A. Watson et al.   ORGANIC LETTERS

Ruthenium-Catalyzed Regioselective Direct Alkylation of Arenes with Unactivated Alkyl Halides through CH Bond Cleavage

(2009) Lutz Ackermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hydrogen Autotransfer in theN-Alkylation of Amines and Related Compounds using Alcohols and Amines as Electrophiles

(2009) Gabriela Guillena et al.   CHEMICAL REVIEWS

Dehydrogenation as a Substrate-Activating Strategy in Homogeneous Transition-Metal Catalysis

(2009) Graham E. Dobereiner et al.   CHEMICAL REVIEWS

Building Molecular ComplexityviaTandem Ru-catalyzed Isomerization/C−H Activation

(2009) Agnieszka Bartoszewicz et al.   ORGANIC LETTERS

Catalytic Carbonyl Addition through Transfer Hydrogenation: A Departure from Preformed Organometallic Reagents

(2008) John F. Bower et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION