C–H bond activation enables the rapid construction and late-stage diversification of functional molecules

Access to Sultams by Rhodium(III)-Catalyzed Directed CH Activation

(2012) Manh V. Pham et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals

(2012) Junichiro Yamaguchi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization

(2012) Percia Beatrice Arockiam et al.   CHEMICAL REVIEWS

From C(sp2)–H to C(sp3)–H: systematic studies on transition metal-catalyzed oxidative C–C formation

(2012) Bi-Jie Li et al.   CHEMICAL SOCIETY REVIEWS

CH Activation: A Complementary Tool in the Total Synthesis of Complex Natural Products

(2012) David Y.-K. Chen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ortho-Functionalized Perylenediimides for Highly Fluorescent Water-Soluble Dyes

(2012) Glauco Battagliarin et al.   CHEMPHYSCHEM

Late-Stage C-H Bond Arylation of Spirocyclic σ1Ligands for Analysis of Complementary σ1Receptor Surface

(2012) Christina Meyer et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Asymmetric Synthesis of Silicon-Stereogenic Dibenzosiloles via Enantioselective C–H Bond Functionalization

(2012) Ryo Shintani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed C–H Activation Taken to the Limit. Flattening an Aromatic Bowl by Total Arylation

(2012) Qianyan Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silicon-Bridged Biaryls: Molecular Design, New Synthesis, and Luminescence Control

(2012) Masaki Shimizu et al.   SYNLETT

Borylation and Silylation of C–H Bonds: A Platform for Diverse C–H Bond Functionalizations

(2011) John F. Hartwig   ACCOUNTS OF CHEMICAL RESEARCH

Palladium-catalysed direct arylation of a tris-cyclometallated Ir(iii) complex bearing 2,2′-thienylpyridine ligands: a powerful tool for the tuning of luminescence properties

(2011) Kassem Beydoun et al.   CHEMICAL COMMUNICATIONS

Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds

(2011) Charles S. Yeung et al.   CHEMICAL REVIEWS

Postsynthetic Methods for the Functionalization of Metal–Organic Frameworks

(2011) Seth M. Cohen   CHEMICAL REVIEWS

Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope

(2011) Lutz Ackermann   CHEMICAL REVIEWS

Towards mild metal-catalyzed C–H bond activation

(2011) Joanna Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

Recent developments in natural product synthesis using metal-catalysed C–H bond functionalisation

(2011) Lindsay McMurray et al.   CHEMICAL SOCIETY REVIEWS

Direct Arylation as a Synthetic Tool for the Synthesis of Thiophene-Based Organic Electronic Materials

(2011) Derek J. Schipper et al.   CHEMISTRY OF MATERIALS

Palladium-Catalyzed CH Bond Functionalization of a Metal-Organic Framework (MOF): Mild, Selective, and Efficient

(2011) Thomas Dröge et al.   CHEMISTRY-A EUROPEAN JOURNAL

Direct Arylation of Polycyclic Aromatic Hydrocarbons through Palladium Catalysis

(2011) Kenji Mochida et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Divergent C–H Functionalizations Directed by Sulfonamide Pharmacophores: Late-Stage Diversification as a Tool for Drug Discovery

(2011) Hui-Xiong Dai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

End-Functionalized Polymerization of 2-Vinylpyridine through Initial C–H Bond Activation ofN-Heteroaromatics and Internal Alkynes by Yttrium Ene–Diamido Complexes

(2011) Hiroshi Kaneko et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploitation of an additional hydrophobic pocket of σ1 receptors: Late-stage diverse modifications of spirocyclic thiophenes by C–H bond functionalization

(2011) Christina Meyer et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Pd(OAc)2/o-Chloranil/M(OTf)n: A Catalyst for the Direct C–H Arylation of Polycyclic Aromatic Hydrocarbons with Boryl-, Silyl-, and Unfunctionalized Arenes

(2011) Katsuaki Kawasumi et al.   ORGANIC LETTERS

Iridium-Catalyzed Direct Tetraborylation of Perylene Bisimides

(2011) Takuro Teraoka et al.   ORGANIC LETTERS

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Pd-Catalyzed Oxidative Cross-Coupling of Perfluoroarenes with Aromatic Heterocycles

(2010) Chun-Yang He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Dehydrohalogenative Polycondensation of 2-Bromo-3-hexylthiophene: An Efficient Approach to Head-to-Tail Poly(3-hexylthiophene)

(2010) Qifeng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Palladium-Catalyzed Oxidative Cycloaromatization of Biaryls with Alkynes Using Molecular Oxygen as the Oxidant

(2009) Zhuangzhi Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed CH Activation/CC Cross-Coupling Reactions: Versatility and Practicality

(2009) Xiao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed C3 or C4 Direct Arylation of Heteroaromatic Compounds with Aryl Halides by CH Bond Activation

(2009) Julien Roger et al.   ChemCatChem

Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation

(2009) Denise A. Colby et al.   CHEMICAL REVIEWS

Regioselective Ru-Catalyzed Direct 2,5,8,11-Alkylation of Perylene Bisimides

(2009) Satomi Nakazono et al.   CHEMISTRY-A EUROPEAN JOURNAL

Fluorescent Diarylindoles by Palladium-Catalyzed Direct and Decarboxylative Arylations of Carboxyindoles

(2009) Mitsuru Miyasaka et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-Catalyzed Intramolecular Coupling of 2-[(2-Pyrrolyl)silyl]aryl Triflates through 1,2-Silicon Migration

(2009) Kenji Mochida et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Efficient Incorporation of Functional Groups into Aromatic Main-Chain Polymer Using Iridium-Catalyzed C−H Activation and Suzuki−Miyaura Reaction

(2009) Tae Soo Jo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Arylated Perylene Bisimides through C−H Bond Cleavage under Ruthenium Catalysis

(2009) Satomi Nakazono et al.   ORGANIC LETTERS

Large polycyclic aromatic hydrocarbons: Synthesis and discotic organization

(2009) Xinliang Feng et al.   PURE AND APPLIED CHEMISTRY

Palladium-Catalyzed Annulation ofvic-Bis(pinacolatoboryl)alkenes and -phenanthrenes with 2,2′-Dibromobiaryls: Facile Synthesis of Functionalized Phenanthrenes and Dibenzo[g,p]chrysenes

(2008) Masaki Shimizu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modular Approach to Silicon-Bridged Biaryls: Palladium-Catalyzed Intramolecular Coupling of 2-(Arylsilyl)aryl Triflates

(2008) Masaki Shimizu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorescent Naphthyl- and Anthrylazoles from the Catalytic Coupling of Phenylazoles with Internal Alkynes through the Cleavage of Multiple CH Bonds

(2008) Nobuyoshi Umeda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Formation of Highly Substituted Naphthalenes from Arene and Alkyne Hydrocarbons

(2008) Yao-Ting Wu et al.   CHEMISTRY-A EUROPEAN JOURNAL