Regioselective C−H Alkylation via Carboxylate-Directed Hydroarylation in Water

Amides as Weak Coordinating Groups in Proximal C-H Bond Activation

(2017) Riki Das et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Route to Substituted Furan-2(5H)-ones from cyclo-Alkenecarboxylic Acids and Acrylates via C–H Activation

(2017) You-Quan Zhu et al.   JOURNAL OF ORGANIC CHEMISTRY

Branched-Selective Intermolecular Ketone α-Alkylation with Unactivated Alkenes via an Enamide Directing Strategy

(2017) Dong Xing et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-Catalyzed Regioselective Anti-Markovnikov Addition of C–H Bonds in Aromatic Ketones to Alkenes

(2017) Naoki Kimura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanisms and Origins of Chemo- and Regioselectivities of Ru(II)-Catalyzed Decarboxylative C–H Alkenylation of Aryl Carboxylic Acids with Alkynes: A Computational Study

(2017) Jing-Lu Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ru(II)-Catalyzed C–H Functionalization on Maleimides with Electrophiles: A Demonstration of Umpolung Strategy

(2017) Suman Dana et al.   ORGANIC LETTERS

Doubly Regioselective C–H Hydroarylation of Unsymmetrical Alkynes Using Carboxylates as Deciduous Directing Groups

(2017) Agostino Biafora et al.   ORGANIC LETTERS

Iridium-Catalyzed, Weakly Coordination-Assisted Ortho-Alkynylation of (Hetero)aromatic Carboxylic Acids without Cyclization

(2017) Changpeng Chen et al.   ORGANIC LETTERS

Ruthenium(II)-Catalyzed C–H Alkynylation of Weakly Coordinating Benzoic Acids

(2017) Ruhuai Mei et al.   ORGANIC LETTERS

Ruthenium(II)-Catalyzed Hydroarylation of Maleimides Using Carboxylic Acids as a Traceless Directing Group

(2017) Anup Mandal et al.   ORGANIC LETTERS

Development of a Kilogram-Scale Process for the Enantioselective Synthesis of 3-Isopropenyl-cyclohexan-1-one via Rh/DTBM-SEGPHOS-Catalyzed Asymmetric Hayashi Addition Enabled by 1,3-Diol Additives

(2017) Eric M. Simmons et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Rh(III)-catalyzed C−H alkylation of indolines with enones through conjugate addition and protonation pathway

(2017) Hyunjung Oh et al.   TETRAHEDRON

Regioselective C−H Hydroarylation of Internal Alkynes with Arenecarboxylates: Carboxylates as Deciduous Directing Groups

(2016) Liangbin Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium-Catalyzed Hydroarylation and One-Pot Twofold Unsymmetrical C−H Functionalization of Arenes

(2016) Koushik Ghosh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium(II)-Catalyzed Decarboxylative C−H Activation: Versatile Routes tometa-Alkenylated Arenes

(2016) N. Y. Phani Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed Tandem Synthesis of Acenes Using Carboxylic Acids as Traceless Directing Groups

(2016) Kiho Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carboxylic Acids as Directing Groups for C−H Bond Functionalization

(2016) Martin Pichette Drapeau et al.   CHEMISTRY-A EUROPEAN JOURNAL

Mechanism of iridium-catalysed branched-selective hydroarylation of vinyl ethers: a computational study

(2016) Mei Zhang et al.   DALTON TRANSACTIONS

Iron-Catalyzed Ortho C–H Methylation of Aromatics Bearing a Simple Carbonyl Group with Methylaluminum and Tridentate Phosphine Ligand

(2016) Rui Shang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Alkylation of N-Sulfonylbenzamides with Vinyl Ethers via C–H Bond Activation Catalyzed by Hydroxoiridium/Chiral Diene Complexes

(2016) Miyuki Hatano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh-catalyzed asymmetric 1,4-addition reactions to α,β-unsaturated carbonyl and related compounds: an update

(2016) Majid M. Heravi et al.   TETRAHEDRON-ASYMMETRY

Mechanism and Origins of Ligand-Controlled Linear Versus Branched Selectivity of Iridium-Catalyzed Hydroarylation of Alkenes

(2016) Genping Huang et al.   ACS Catalysis

Cationic Iridium/S-Me-BIPAM-Catalyzed Direct Asymmetric Intermolecular Hydroarylation of Bicycloalkenes

(2015) Tomohiko Shirai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carboxylic Acids as Traceless Directing Groups for the Rhodium(III)-Catalyzed Decarboxylative CH Arylation of Thiophenes

(2015) Yuanfei Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium Oxidase Catalysis for Site-Selective C-H Alkenylations with Ambient O2 as the Sole Oxidant

(2015) Alexander Bechtoldt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(I)-Catalyzed Regiospecific Dimerization of Aromatic Acids: Two Direct CH Bond Activations in Water

(2015) Hang Gong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iridium-Catalyzedortho-Arylation of Benzoic Acids with Arenediazonium Salts

(2015) Liangbin Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)-CatalyzedorthoCH Heteroarylation of (Hetero)aromatic Carboxylic Acids: A Rapid and Concise Access to π-Conjugated Poly-heterocycles

(2015) Xurong Qin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Methodologies Limiting or Avoiding Contamination by Organotin Residues in Organic Synthesis

(2015) Erwan Le Grognec et al.   CHEMICAL REVIEWS

Transition-Metal-Catalyzed Direct Addition of Unactivated C–H Bonds to Polar Unsaturated Bonds

(2015) Lei Yang et al.   CHEMICAL REVIEWS

Transition metal-catalyzed ketone-directed or mediated C–H functionalization

(2015) Zhongxing Huang et al.   CHEMICAL SOCIETY REVIEWS

Practical Pd(II)-Catalyzed C–H Alkylation with Epoxides: One-Step Syntheses of 3,4-Dihydroisocoumarins

(2015) Guolin Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Complete Switch of Selectivity in the C–H Alkenylation and Hydroarylation Catalyzed by Iridium: The Role of Directing Groups

(2015) Jiyu Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iridium-Catalyzed Branch-Selective Hydroarylation of Vinyl Ethers via C–H Bond Activation

(2015) Yusuke Ebe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site-Selective Addition of Maleimide to Indole at the C-2 Position: Ru(II)-Catalyzed C–H Activation

(2015) Veeranjaneyulu Lanke et al.   ORGANIC LETTERS

Rh(III)-Catalyzed Decarboxylative ortho-Heteroarylation of Aromatic Carboxylic Acids by Using the Carboxylic Acid as a Traceless Directing Group

(2015) Xurong Qin et al.   ORGANIC LETTERS

Rhodium-Catalyzed Alkylation of C–H Bonds in Aromatic Amides with Styrenes via Bidentate–Chelation Assistance

(2015) Kaname Shibata et al.   ORGANIC LETTERS

Ruthenium(ii)-catalyzed switchable C3-alkylation versus alkenylation with acrylates of 2-pyridylbenzofurans via C–H bond activation

(2015) Yadagiri Kommagalla et al.   Catalysis Science & Technology

Transition metal-catalyzed C–H bond functionalizations by the use of diverse directing groups

(2015) Zhengkai Chen et al.   Organic Chemistry Frontiers

Carboxylate-Directed CH Functionalization

(2014) Guangfa Shi et al.   ADVANCED SYNTHESIS & CATALYSIS

Highly Linear Selective Cobalt-Catalyzed Addition of Aryl Imines to Styrenes: Reversing Intrinsic Regioselectivity by Ligand Elaboration

(2014) Wengang Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iridium-Catalyzed Enantioselective CH Alkylation of Ferrocenes with Alkenes Using Chiral Diene Ligands

(2014) Takanori Shibata et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Extended π-Systems through C-H Activation

(2014) Yasutomo Segawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Overriding Ortho–Para Selectivity via a Traceless Directing Group Relay Strategy: The Meta-Selective Arylation of Phenols

(2014) Junfei Luo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzedortho Acylation of Aromatic Carboxylic Acids

(2013) Patrizia Mamone et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carboxylate-Assisted Ruthenium(II)-Catalyzed Hydroarylations of Unactivated Alkenes through C-H Cleavage

(2013) Marvin Schinkel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Aryl Ethers from Benzoates through Carboxylate-Directed CH-Activating Alkoxylation with Concomitant Protodecarboxylation

(2013) Sukalyan Bhadra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)-Catalyzed Intramolecular Hydroarylation, Amidoarylation, and Heck-type Reaction: Three Distinct Pathways Determined by an Amide Directing Group

(2013) Tyler A. Davis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mild Rhodium(III)-Catalyzed Cyclization of Amides with α,β-Unsaturated Aldehydes and Ketones to Azepinones: Application to the Synthesis of the Homoprotoberberine Framework

(2013) Zhuangzhi Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ligand-Accelerated ortho-C–H Alkylation of Arylcarboxylic Acids using Alkyl Boron Reagents

(2013) Peter S. Thuy-Boun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Indene Frameworks via Rhodium-Catalyzed Cascade Cyclization of Aromatic Ketone and Unsaturated Carbonyl Compounds

(2013) Xian-Ying Shi et al.   ORGANIC LETTERS

Ruthenium-catalyzed ortho-C–H bond alkylation of aromatic amides with α,β-unsaturated ketones via bidentate-chelation assistance

(2013) Guy Rouquet et al.   Chemical Science

CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals

(2012) Junichiro Yamaguchi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Brønsted Acid Enhanced Rhodium-Catalyzed Conjugate Addition of Aryl CH Bonds to α,β-Unsaturated Ketones under Mild Conditions

(2012) Lei Yang et al.   CHEMISTRY-A EUROPEAN JOURNAL

CH Activation: A Complementary Tool in the Total Synthesis of Complex Natural Products

(2012) David Y.-K. Chen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rh(III)-Catalyzed Regioselective Synthesis of Pyridines from Alkenes and α,β-Unsaturated Oxime Esters

(2012) Jamie M. Neely et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ruthenium-Catalyzed Oxidative C–H Alkenylations of Anilides and Benzamides in Water

(2012) Lutz Ackermann et al.   ORGANIC LETTERS

[Ir(cod)2]BARF-Catalyzed C–H Bond Alkenylation and Alkylation of Ferrocenes

(2012) Satoshi Takebayashi et al.   ORGANOMETALLICS

Carboxylic Acids as Traceless Directing Groups for Formal meta-Selective Direct Arylation

(2011) Josep Cornella et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Cross-Coupling Reaction of Organoboron Compounds with Primary Alkyl Halides and Pseudohalides

(2011) Chu-Ting Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent developments in natural product synthesis using metal-catalysed C–H bond functionalisation

(2011) Lindsay McMurray et al.   CHEMICAL SOCIETY REVIEWS

Cobalt-Catalyzed Chemoselective Insertion of Alkene into the Ortho C−H Bond of Benzamide

(2011) Laurean Ilies et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-catalyzed C–H activation and conjugate addition under mild conditions

(2011) Luo Yang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Ruthenium-Catalyzed Oxidative C–H Bond Alkenylations in Water: Expedient Synthesis of Annulated Lactones

(2011) Lutz Ackermann et al.   ORGANIC LETTERS

Ruthenium-Catalyzed Oxidative Vinylation of Heteroarene Carboxylic Acids with Alkenes via Regioselective C−H Bond Cleavage

(2011) Takumi Ueyama et al.   ORGANIC LETTERS

Ruthenium-Catalyzed C–H/N–O Bond Functionalization: Green Isoquinolone Syntheses in Water

(2011) Lutz Ackermann et al.   ORGANIC LETTERS

CH Bond Functionalization in Water Catalyzed by Carboxylato Ruthenium(II) Systems

(2010) Percia B. Arockiam et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Addition of Metal Enolate Derivatives to Unactivated Carbon−Carbon Multiple Bonds

(2010) Fabrice Dénès et al.   CHEMICAL REVIEWS

Organic Reactions Catalyzed by Rhenium Carbonyl Complexes

(2010) Yoichiro Kuninobu et al.   CHEMICAL REVIEWS

Decarboxylative Coupling Reactions

(2010) Lukas J. Goossen et al.   ISRAEL JOURNAL OF CHEMISTRY

A Graphical Journey of Innovative Organic Architectures That Have Improved Our Lives

(2010) Nicholas A. McGrath et al.   JOURNAL OF CHEMICAL EDUCATION

Palladium(II)-CatalyzedorthoAlkylation of Benzoic Acids with Alkyl Halides

(2009) Yang-Hui Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Impact of Natural Products on Developing New Anti-Cancer Agents†

(2009) Gordon M. Cragg et al.   CHEMICAL REVIEWS

Building Molecular ComplexityviaTandem Ru-catalyzed Isomerization/C−H Activation

(2009) Agnieszka Bartoszewicz et al.   ORGANIC LETTERS

Catalytic Asymmetric Friedel−Crafts Alkylation ReactionsCopper Showed the Way

(2008) Thomas B. Poulsen et al.   CHEMICAL REVIEWS