Crosstalk between oncolytic viruses and autophagy in cancer therapy

Autophagy as a Cellular Stress Response Mechanism in the Nervous System

(2020) Nesibe Peker et al.   JOURNAL OF MOLECULAR BIOLOGY

Enhancing therapeutic efficacy of oncolytic vaccinia virus armed with Beclin-1, an autophagic Gene in leukemia and myeloma

(2020) Wen Lei et al.   BIOMEDICINE & PHARMACOTHERAPY

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I

(2020) Keisuke Yamamoto et al.   NATURE

Autophagy Inhibits TLR4-mediated Invasiveness of Oral cancer Cells Via the NF-κB Pathway

(2020) Qianying Kong et al.   ORAL DISEASES

The Role of Mitochondrial Dynamics and Mitophagy in Carcinogenesis, Metastasis and Therapy

(2020) Yigang Wang et al.   Frontiers in Cell and Developmental Biology

The relationship between autophagy and the immune system and its applications for tumor immunotherapy

(2019) Guan-Min Jiang et al.   Molecular Cancer

STAT3 Contributes To Oncolytic Newcastle Disease Virus-Induced Immunogenic Cell Death in Melanoma Cells

(2019) Xiaoyan Shao et al.   Frontiers in Oncology

DNX-2401: an investigational drug for the treatment of recurrent glioblastoma

(2019) Brandon Philbrick et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

A Phase I clinical trial of EUS-guided intratumoral injection of the oncolytic virus, HF10 for unresectable locally advanced pancreatic cancer

(2018) Yoshiki Hirooka et al.   BMC CANCER

Targeting autophagy in cancer

(2018) Angelique V. Onorati et al.   CANCER

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Oncorine, the World First Oncolytic Virus Medicine and its Update in China

(2018) Min Liang   CURRENT CANCER DRUG TARGETS

Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells

(2018) Qing Fan et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Mechanism and medical implications of mammalian autophagy

(2018) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence

(2018) Laura Vera-Ramirez et al.   Nature Communications

Talimogene laherparepvec: First in class oncolytic virotherapy

(2018) Robert M. Conry et al.   Human Vaccines & Immunotherapeutics

Oncolytic adenovirus: A tool for cancer therapy in combination with other therapeutic approaches

(2018) Nasser Hashemi Goradel et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Role of autophagy in tumorigenesis, metastasis, targeted therapy and drug resistance of hepatocellular carcinoma

(2018) Fang Huang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Combination of immunogenic oncolytic adenovirus ONCOS-102 with anti-PD-1 pembrolizumab exhibits synergistic antitumor effect in humanized A2058 melanoma huNOG mouse model

(2018) Lukasz Kuryk et al.   OncoImmunology

Targeting Autophagy in Cancer: Update on Clinical Trials and Novel Inhibitors

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Interferon-Mediated Tumor Resistance to Oncolytic Virotherapy

(2017) Safieh Ebrahimi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Recent advances in vesicular stomatitis virus-based oncolytic virotherapy: a 5-year update

(2017) Sébastien A. Felt et al.   JOURNAL OF GENERAL VIROLOGY

Autophagy promotes apoptosis induction through repressed nitric oxide generation in the treatment of human breast cancer MCF-7 cells with L-A03, a dihydroartemisinin derivative

(2017) Guodong Yao et al.   MEDICINAL CHEMISTRY RESEARCH

Activation of Nrf2 Signaling Augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity

(2017) David Olagnier et al.   MOLECULAR THERAPY

Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M

(2017) Marianne D. Hansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic Signature of the Natural Oncolytic Herpes Simplex Virus HF10 and Its Therapeutic Role in Preclinical and Clinical Trials

(2017) Ibrahim Ragab Eissa et al.   Frontiers in Oncology

Genetically Engineered Vaccinia Viruses As Agents for Cancer Treatment, Imaging, and Transgene Delivery

(2017) Dana Haddad   Frontiers in Oncology

Measles to the Rescue: A Review of Oncolytic Measles Virus

(2016) Sarah Aref et al.   Viruses-Basel

Moving oncolytic viruses into the clinic: clinical-grade production, purification, and characterization of diverse oncolytic viruses

(2016) Guy Ungerechts et al.   Molecular Therapy-Methods & Clinical Development

The intersection between viral oncolysis, drug resistance, and autophagy

(2015) Vladimir Beljanski et al.   BIOLOGICAL CHEMISTRY

Molecular Pathways: Mechanism of Action for Talimogene Laherparepvec, a New Oncolytic Virus Immunotherapy

(2015) F. J. Kohlhapp et al.   CLINICAL CANCER RESEARCH

Autophagy in malignant transformation and cancer progression

(2015) L. Galluzzi et al.   EMBO JOURNAL

Vaccinia virus, a promising new therapeutic agent for pancreatic cancer

(2015) Chadwan Al Yaghchi et al.   Immunotherapy

Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells

(2015) Wenjie Qin et al.   Oncotarget

The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation

(2015) Yongjie Wei et al.   eLife

Potent antitumor activity of oncolytic adenovirus expressing Beclin-1 via induction of autophagic cell death in leukemia

(2015) Yin Tong et al.   Oncotarget

Newcastle disease virotherapy induces long-term survival and tumor-specific immune memory in orthotopic glioma through the induction of immunogenic cell death

(2014) Carolien A. Koks et al.   INTERNATIONAL JOURNAL OF CANCER

Mitophagy Enhances Oncolytic Measles Virus Replication by Mitigating DDX58/RIG-I-Like Receptor Signaling

(2014) M. Xia et al.   JOURNAL OF VIROLOGY

Autophagy promotes paclitaxel resistance of cervical cancer cells: involvement of Warburg effect activated hypoxia-induced factor 1-α-mediated signaling

(2014) X Peng et al.   Cell Death & Disease

An Overview of Autophagy: Morphology, Mechanism, and Regulation

(2013) Katherine R. Parzych et al.   ANTIOXIDANTS & REDOX SIGNALING

Enhanced autophagy blocks angiogenesis via degradation of gastrin-releasing peptide in neuroblastoma cells

(2013) Kwang Woon Kim et al.   Autophagy

Autophagy promotes hepatocellular carcinoma cell invasion through activation of epithelial–mesenchymal transition

(2013) Jun Li et al.   CARCINOGENESIS

Multimodal immunogenic cancer cell death as a consequence of anticancer cytotoxic treatments

(2013) H Inoue et al.   CELL DEATH AND DIFFERENTIATION

Autophagy regulation by nutrient signaling

(2013) Ryan C Russell et al.   CELL RESEARCH

The effectiveness of the oncolytic activity induced by Ad5/F35 adenoviral vector is dependent on the cumulative cellular conditions of survival and autophagy

(2013) SO Y. KIM et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Autophagy and Viruses: Adversaries or Allies?

(2013) Xiaonan Dong et al.   Journal of Innate Immunity

Histone Deacetylase Inhibitors Potentiate Vesicular Stomatitis Virus Oncolysis in Prostate Cancer Cells by Modulating NF- B-Dependent Autophagy

(2013) L. Shulak et al.   JOURNAL OF VIROLOGY

Oncolytic Adenovirus With Temozolomide Induces Autophagy and Antitumor Immune Responses in Cancer Patients

(2013) Ilkka Liikanen et al.   MOLECULAR THERAPY

Combination of autophagy inducer rapamycin and oncolytic adenovirus improves antitumor effect in cancer cells

(2013) Pei-Hsin Cheng et al.   Virology Journal

Strange attractors: DAMPs and autophagy link tumor cell death and immunity

(2013) W Hou et al.   Cell Death & Disease

Sustained Autophagy Contributes to Measles Virus Infectivity

(2013) Clémence Richetta et al.   PLoS Pathogens

IRGM in autophagy and viral infections

(2013) Denitsa S. Petkova et al.   Frontiers in Immunology

Autophagy and the Immune System

(2012) Petric Kuballa et al.   Annual Review of Immunology

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Newcastle disease virus triggers autophagy in U251 glioma cells to enhance virus replication

(2012) Chunchun Meng et al.   ARCHIVES OF VIROLOGY

Preclinical efficacy of the oncolytic measles virus expressing the sodium iodide symporter in iodine non-avid anaplastic thyroid cancer: a novel therapeutic agent allowing noninvasive imaging and radioiodine therapy

(2012) H V Reddi et al.   CANCER GENE THERAPY

Oncolytic HSV-1 Virotherapy: Clinical Experience and Opportunities for Progress

(2012) Balveen Kaur et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Inhibition of Autophagy Enhances the Effects of E1A-Defective Oncolytic Adenovirus dl922–947 Against Glioma Cells In Vitro and In Vivo

(2012) Ginevra Botta et al.   HUMAN GENE THERAPY

Genetically engineered oncolytic adenovirus induces autophagic cell death through an E2F1-microRNA-7-epidermal growth factor receptor axis

(2012) Hiroshi Tazawa et al.   INTERNATIONAL JOURNAL OF CANCER

Autophagy and cancer - issues we need to digest

(2012) E. Y. Liu et al.   JOURNAL OF CELL SCIENCE

Vesicular stomatitis virus as a flexible platform for oncolytic virotherapy against cancer

(2012) E. Hastie et al.   JOURNAL OF GENERAL VIROLOGY

Host Cell Autophagy Modulates Early Stages of Adenovirus Infections in Airway Epithelial Cells

(2012) X. Zeng et al.   JOURNAL OF VIROLOGY

Autophagy in the regulation of pathogen replication and adaptive immunity

(2012) Felix Randow et al.   TRENDS IN IMMUNOLOGY

Immunogenic Cell Death: Can It Be Exploited in PhotoDynamic Therapy for Cancer?

(2012) Elisa Panzarini et al.   Biomed Research International

Selective autophagy and viruses

(2011) Rhea Sumpter et al.   Autophagy

Autophagy and cytokines

(2011) James Harris   CYTOKINE

Human Adenovirus Type 5 Induces Cell Lysis through Autophagy and Autophagy-Triggered Caspase Activity

(2011) H. Jiang et al.   JOURNAL OF VIROLOGY

Adenoviruses induce autophagy to promote virus replication and oncolysis

(2011) Humberto Rodriguez-Rocha et al.   VIROLOGY

CD91-dependent programming of T-helper cell responses following heat shock protein immunization

(2011) Sudesh Pawaria et al.   Nature Communications

Regulation of Autophagy by Kinases

(2011) Savitha Sridharan et al.   Cancers

Pathogen recognition by the cell surface receptor CD46 induces autophagy

(2010) Grégory Meiffren et al.   Autophagy

Oncolytic vaccinia virus: a silver bullet?

(2010) Monika Lusky et al.   Expert Review of Vaccines

Identification of Genetically Modified Maraba Virus as an Oncolytic Rhabdovirus

(2010) Jan Brun et al.   MOLECULAR THERAPY

A single intravenous injection of oncolytic picornavirus SVV-001 eliminates medulloblastomas in primary tumor-based orthotopic xenograft mouse models

(2010) L. Yu et al.   NEURO-ONCOLOGY

Immunogenic cell death, DAMPs and anticancer therapeutics: An emerging amalgamation

(2009) Abhishek D. Garg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Eating Twice for the Sake of Immunity: A Phagocytic Receptor that Activates Autophagy

(2009) Shahab Shahnazari et al.   Cell Host & Microbe

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

(2009) Michael R. Elliott et al.   NATURE

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

Viruses and autophagy

(2009) Sagar B. Kudchodkar et al.   REVIEWS IN MEDICAL VIROLOGY

The effects of trichostatin A on the oncolytic ability of herpes simplex virus for oral squamous cell carcinoma cells

(2008) T Katsura et al.   CANCER GENE THERAPY

Autophagy regulates selective HMGB1 release in tumor cells that are destined to die

(2008) J Thorburn et al.   CELL DEATH AND DIFFERENTIATION

Autophagy-inducing agents augment the antitumor effect of telerase-selve oncolytic adenovirus OBP-405 on glioblastoma cells

(2008) T Yokoyama et al.   GENE THERAPY

Chemical targeting of the innate antiviral response by histone deacetylase inhibitors renders refractory cancers sensitive to viral oncolysis

(2008) T. L.-A. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA