Interferon-Mediated Tumor Resistance to Oncolytic Virotherapy

STAT1 and NF- B Inhibitors Diminish Basal Interferon-Stimulated Gene Expression and Improve the Productive Infection of Oncolytic HSV in MPNST Cells

(2016) J. D. Jackson et al.   MOLECULAR CANCER RESEARCH

Application of interferon modulators to overcome partial resistance of human ovarian cancers to VSV-GP oncolytic viral therapy

(2016) Catherine Dold et al.   Molecular Therapy-Oncolytics

Breaking resistance of pancreatic cancer cells to an attenuated vesicular stomatitis virus through a novel activity of IKK inhibitor TPCA-1

(2015) Marcela Cataldi et al.   VIROLOGY

The unique regulation and functions of type III interferons in antiviral immunity

(2015) Charlotte Odendall et al.   Current Opinion in Virology

Combination of the oral histone deacetylase inhibitor resminostat with oncolytic measles vaccine virus as a new option for epi-virotherapeutic treatment of hepatocellular carcinoma

(2015) Benjamin Ruf et al.   Molecular Therapy-Oncolytics

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

ISG15 Functions as an Interferon-Mediated Antiviral Effector Early in the Murine Norovirus Life Cycle

(2014) M. R. Rodriguez et al.   JOURNAL OF VIROLOGY

Interferon-Induced Ifit Proteins: Their Role in Viral Pathogenesis

(2014) Volker Fensterl et al.   JOURNAL OF VIROLOGY

Success of measles virotherapy in ATL depends on type I interferon secretion and responsiveness

(2014) M. Cecilia M. Parrula et al.   VIRUS RESEARCH

Overcoming cancer cell resistance to VSV oncolysis with JAK1/2 inhibitors

(2013) D Escobar-Zarate et al.   CANCER GENE THERAPY

The Antiviral Effector IFITM3 Disrupts Intracellular Cholesterol Homeostasis to Block Viral Entry

(2013) Samad Amini-Bavil-Olyaee et al.   Cell Host & Microbe

Innate Immune Defense Defines Susceptibility of Sarcoma Cells to Measles Vaccine Virus-Based Oncolysis

(2013) S. Berchtold et al.   JOURNAL OF VIROLOGY

Triptolide-Mediated Inhibition of Interferon Signaling Enhances Vesicular Stomatitis Virus-Based Oncolysis

(2013) Fethia Ben Yebdri et al.   MOLECULAR THERAPY

Induction of antiviral genes by the tumor microenvironment confers resistance to virotherapy

(2013) Yu-Ping Liu et al.   Scientific Reports

Vesicular Stomatitis Virus as an Oncolytic Agent against Pancreatic Ductal Adenocarcinoma

(2012) A. M. Murphy et al.   JOURNAL OF VIROLOGY

The Histone Deacetylase Inhibitor Valproic Acid Lessens NK Cell Action against Oncolytic Virus-Infected Glioblastoma Cells by Inhibition of STAT5/T-BET Signaling and Generation of Gamma Interferon

(2012) Christopher A. Alvarez-Breckenridge et al.   JOURNAL OF VIROLOGY

Interferon-β Sensitivity of Tumor Cells Correlates With Poor Response to VA7 Virotherapy in Mouse Glioma Models

(2012) Janne Ruotsalainen et al.   MOLECULAR THERAPY

Resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus: Role of type I interferon signaling

(2012) Megan Moerdyk-Schauwecker et al.   VIROLOGY

Sensitivity of cervical carcinoma cells to vesicular stomatitis virus-induced oncolysis: Potential role of human papilloma virus infection

(2011) Fabrice Le Boeuf et al.   INTERNATIONAL JOURNAL OF CANCER

Role of Promyelocytic Leukemia Protein in Host Antiviral Defense

(2011) Marie-Claude Geoffroy et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Vesicular Stomatitis Virus Has Extensive Oncolytic Activity against Human Sarcomas: Rare Resistance Is Overcome by Blocking Interferon Pathways

(2011) J. C. Paglino et al.   JOURNAL OF VIROLOGY

Induction of Interferon Pathways Mediates In Vivo Resistance to Oncolytic Adenovirus

(2011) Ilkka Liikanen et al.   MOLECULAR THERAPY

Oncolytic Sindbis Virus Targets Tumors Defective in the Interferon Response and Induces Significant Bystander Antitumor Immunity In Vivo

(2011) Pong-Yu Huang et al.   MOLECULAR THERAPY

Epigenetic Silencing of IRF7 and/or IRF5 in Lung Cancer Cells Leads to Increased Sensitivity to Oncolytic Viruses

(2011) Qunfang Li et al.   PLoS One

Human MxA Protein: An Interferon-Induced Dynamin-Like GTPase with Broad Antiviral Activity

(2010) Otto Haller et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type I IFN production

(2010) T. Alain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone Deacetylase Inhibitors Augment Antitumor Efficacy of Herpes-based Oncolytic Viruses

(2008) Akihiro Otsuki et al.   MOLECULAR THERAPY

Inhibition of the IFN-β Response in Hepatocellular Carcinoma by Alternative Spliced Isoform of IFN Regulatory Factor-3

(2008) Sabrina Marozin et al.   MOLECULAR THERAPY

RAPping production of type I interferon in pDCs through mTOR

(2008) Mauro Costa-Mattioli et al.   NATURE IMMUNOLOGY

Chemical targeting of the innate antiviral response by histone deacetylase inhibitors renders refractory cancers sensitive to viral oncolysis

(2008) T. L.-A. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA