Vesicular stomatitis virus as a flexible platform for oncolytic virotherapy against cancer

The eIF2α kinases inhibit vesicular stomatitis virus replication independently of eIF2 phosphorylation.

(2014) Jothi Krishnamoorthy et al.   CELL CYCLE

Semireplication-competent vesicular stomatitis virus as a novel platform for oncolytic virotherapy

(2012) Alexander Muik et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Vesicular Stomatitis Virus as an Oncolytic Agent against Pancreatic Ductal Adenocarcinoma

(2012) A. M. Murphy et al.   JOURNAL OF VIROLOGY

Curative one-shot systemic virotherapy in murine myeloma

(2012) S Naik et al.   LEUKEMIA

Using virally expressed melanoma cDNA libraries to identify tumor-associated antigens that cure melanoma

(2012) Jose Pulido et al.   NATURE BIOTECHNOLOGY

Targeting pediatric cancer stem cells with oncolytic virotherapy

(2012) Gregory K. Friedman et al.   PEDIATRIC RESEARCH

Electrochemical Sensing of Aptamer-Facilitated Virus Immunoshielding

(2011) Mahmoud Labib et al.   ANALYTICAL CHEMISTRY

Enhancing VSV oncolytic activity with an improved cytosine deaminase suicide gene strategy

(2011) S Leveille et al.   CANCER GENE THERAPY

Expressing human interleukin-15 from oncolytic vesicular stomatitis virus improves survival in a murine metastatic colon adenocarcinoma model through the enhancement of anti-tumor immunity

(2011) K B Stephenson et al.   CANCER GENE THERAPY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Interferon-Induced Tetherin Restricts Vesicular Stomatitis Virus Release in Neurons

(2011) Sreeja Sarojini et al.   DNA AND CELL BIOLOGY

Activating Systemic T-Cell Immunity Against Self Tumor Antigens to Support Oncolytic Virotherapy with Vesicular Stomatitis Virus

(2011) Phonphimon Wongthida et al.   HUMAN GENE THERAPY

Retargeting Vesicular Stomatitis Virus Using Measles Virus Envelope Glycoproteins

(2011) Camilo Ayala-Breton et al.   HUMAN GENE THERAPY

Sensitivity of cervical carcinoma cells to vesicular stomatitis virus-induced oncolysis: Potential role of human papilloma virus infection

(2011) Fabrice Le Boeuf et al.   INTERNATIONAL JOURNAL OF CANCER

Interferon: Current Status and Future Prospects in Cancer Therapy

(2011) Ben X. Wang et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Detecting protein–protein interactions in vesicular stomatitis virus using a cytoplasmic yeast two hybrid system

(2011) Megan Moerdyk-Schauwecker et al.   JOURNAL OF VIROLOGICAL METHODS

Vesicular Stomatitis Virus Expressing Tumor Suppressor p53 Is a Highly Attenuated, Potent Oncolytic Agent

(2011) J. F. Heiber et al.   JOURNAL OF VIROLOGY

Oncolytic Vesicular Stomatitis Virus Induces Apoptosis in U87 Glioblastoma Cells by a Type II Death Receptor Mechanism and Induces Cell Death and Tumor Clearance In Vivo

(2011) Z. D. Cary et al.   JOURNAL OF VIROLOGY

Vesicular Stomatitis Virus Oncolytic Treatment Interferes with Tumor-Associated Dendritic Cell Functions and Abrogates Tumor Antigen Presentation

(2011) S. Leveille et al.   JOURNAL OF VIROLOGY

Antagonistic Effects of Cellular Poly(C) Binding Proteins on Vesicular Stomatitis Virus Gene Expression

(2011) P. X. Dinh et al.   JOURNAL OF VIROLOGY

Pseudotyping Vesicular Stomatitis Virus with Lymphocytic Choriomeningitis Virus Glycoproteins Enhances Infectivity for Glioma Cells and Minimizes Neurotropism

(2011) A. Muik et al.   JOURNAL OF VIROLOGY

Mutations in the Glycoprotein of Vesicular Stomatitis Virus Affect Cytopathogenicity: Potential for Oncolytic Virotherapy

(2011) V. Janelle et al.   JOURNAL OF VIROLOGY

A Recombinant Vesicular Stomatitis Virus Bearing a Lethal Mutation in the Glycoprotein Gene Uncovers a Second Site Suppressor That Restores Fusion

(2011) M. L. Stanifer et al.   JOURNAL OF VIROLOGY

Targeting Tumor Vasculature With an Oncolytic Virus

(2011) Caroline J Breitbach et al.   MOLECULAR THERAPY

Thunder and Lightning: Immunotherapy and Oncolytic Viruses Collide

(2011) Alan Melcher et al.   MOLECULAR THERAPY

Vesicular Stomatitis Virus Infection Promotes Immune Evasion by Preventing NKG2D-Ligand Surface Expression

(2011) Helle Jensen et al.   PLoS One

Epigenetic Silencing of IRF7 and/or IRF5 in Lung Cancer Cells Leads to Increased Sensitivity to Oncolytic Viruses

(2011) Qunfang Li et al.   PLoS One

The protease-sensitive loop of the vesicular stomatitis virus matrix protein is involved in virus assembly and protein translation

(2011) Chad E. Mire et al.   VIROLOGY

Type III IFN Interleukin-28 Mediates the Antitumor Efficacy of Oncolytic Virus VSV in Immune-Competent Mouse Models of Cancer

(2010) Phonphimon Wongthida et al.   CANCER RESEARCH

Oncolysis of Prostate Cancers Induced by Vesicular Stomatitis Virus in PTEN Knockout Mice

(2010) M. Moussavi et al.   CANCER RESEARCH

Directing systemic oncolytic viral delivery to tumors via carrier cells☆

(2010) Hiroshi Nakashima et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Phosphorylation of the NFAR proteins by the dsRNA-dependent protein kinase PKR constitutes a novel mechanism of translational regulation and cellular defense

(2010) A. Harashima et al.   GENES & DEVELOPMENT

Current Good Manufacturing Practice Production of an Oncolytic Recombinant Vesicular Stomatitis Viral Vector for Cancer Treatment

(2010) L.J. Ausubel et al.   HUMAN GENE THERAPY

A Novel Toll-like Receptor That Recognizes Vesicular Stomatitis Virus

(2010) Zhongcheng Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antiangiogenic cancer therapy combined with oncolytic virotherapy leads to regression of established tumors in mice

(2010) Timothy Kottke et al.   JOURNAL OF CLINICAL INVESTIGATION

Fusion-active glycoprotein G mediates the cytotoxicity of vesicular stomatitis virus M mutants lacking host shut-off activity

(2010) M. Hoffmann et al.   JOURNAL OF GENERAL VIROLOGY

Enhanced Oncolytic Activity of Vesicular Stomatitis Virus Encoding SV5-F Protein Against Prostate Cancer

(2010) Guimin Chang et al.   JOURNAL OF UROLOGY

Interferon-Induced Cell Membrane Proteins, IFITM3 and Tetherin, Inhibit Vesicular Stomatitis Virus Infection via Distinct Mechanisms

(2010) J. M. Weidner et al.   JOURNAL OF VIROLOGY

Potentiating Cancer Immunotherapy Using an Oncolytic Virus

(2010) Byram W Bridle et al.   MOLECULAR THERAPY

Synergistic Interaction Between Oncolytic Viruses Augments Tumor Killing

(2010) Fabrice Le Boeuf et al.   MOLECULAR THERAPY

VSV Oncolysis in Combination With the BCL-2 Inhibitor Obatoclax Overcomes Apoptosis Resistance in Chronic Lymphocytic Leukemia

(2010) Sara Samuel et al.   MOLECULAR THERAPY

VSV Oncolytic Virotherapy in the B16 Model Depends Upon Intact MyD88 Signaling

(2010) Phonphimon Wongthida et al.   MOLECULAR THERAPY

Vesicular Stomatitis Virus-induced Immune Suppressor Cells Generate Antagonism Between Intratumoral Oncolytic Virus and Cyclophosphamide

(2010) Candice Willmon et al.   MOLECULAR THERAPY

Oncolytic virotherapy reaches adolescence

(2010) Adrienne M. Hammill et al.   PEDIATRIC BLOOD & CANCER

Cell Cycle Progression or Translation Control Is Not Essential for Vesicular Stomatitis Virus Oncolysis of Hepatocellular Carcinoma

(2010) Sabrina Marozin et al.   PLoS One

Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type I IFN production

(2010) T. Alain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-EM Model of the Bullet-Shaped Vesicular Stomatitis Virus

(2010) P. Ge et al.   SCIENCE

Vesicular stomatitis virus infects resident cells of the central nervous system and induces replication-dependent inflammatory responses

(2010) Vinita S. Chauhan et al.   VIROLOGY

Protein Expression Redirects Vesicular Stomatitis Virus RNA Synthesis to Cytoplasmic Inclusions

(2010) Bianca S. Heinrich et al.   PLoS Pathogens

The Length of Vesicular Stomatitis Virus Particles Dictates a Need for Actin Assembly during Clathrin-Dependent Endocytosis

(2010) David K. Cureton et al.   PLoS Pathogens

Infection of Melanoplus sanguinipes Grasshoppers following Ingestion of Rangeland Plant Species Harboring Vesicular Stomatitis Virus

(2009) B. S. Drolet et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Vesicular stomatitis virus inhibits mitotic progression and triggers cell death

(2009) Papia Chakraborty et al.   EMBO REPORTS

Engineering oncolytic viruses to exploit tumor specific defects in innate immune signaling pathways

(2009) Shruthi Naik et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

VSV virotherapy improves chemotherapy by triggering apoptosis due to proteasomal degradation of Mcl-1

(2009) P Schache et al.   GENE THERAPY

Evaluation of an Attenuated Vesicular Stomatitis Virus Vector Expressing Interferon-β for Use in Malignant Pleural Mesothelioma: Heterogeneity in Interferon Responsiveness Defines Potential Efficacy

(2009) Vassiliki Saloura et al.   HUMAN GENE THERAPY

Safety Studies on Intrahepatic or Intratumoral Injection of Oncolytic Vesicular Stomatitis Virus Expressing Interferon-β in Rodents and Nonhuman Primates

(2009) Nathan Jenks et al.   HUMAN GENE THERAPY

Interference of CD40L-Mediated Tumor Immunotherapy by Oncolytic Vesicular Stomatitis Virus

(2009) Feorillo Galivo et al.   HUMAN GENE THERAPY

Rhabdovirus Evasion of the Interferon System

(2009) Martina Rieder et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Peripheral Immunization Blocks Lethal Actions of Vesicular Stomatitis Virus within the Brain

(2009) K. Ozduman et al.   JOURNAL OF VIROLOGY

Some Attenuated Variants of Vesicular Stomatitis Virus Show Enhanced Oncolytic Activity against Human Glioblastoma Cells relative to Normal Brain Cells

(2009) G. Wollmann et al.   JOURNAL OF VIROLOGY

Attenuation of Vesicular Stomatitis Virus Encephalitis through MicroRNA Targeting

(2009) E. J. Kelly et al.   JOURNAL OF VIROLOGY

Targeting Cancer-initiating Cells With Oncolytic Viruses

(2009) Timothy P Cripe et al.   MOLECULAR THERAPY

Recombinant Vesicular Stomatitis Virus Transduction of Dendritic Cells Enhances Their Ability to Prime Innate and Adaptive Antitumor Immunity

(2009) Jeanette E Boudreau et al.   MOLECULAR THERAPY

Cyclophosphamide Facilitates Antitumor Efficacy against Subcutaneous Tumors following Intravenous Delivery of Reovirus

(2008) J. Qiao et al.   CLINICAL CANCER RESEARCH

Taming the Trojan horse: optimizing dynamic carrier cell/oncolytic virus systems for cancer biotherapy

(2008) A T Power et al.   GENE THERAPY

Loading of oncolytic vesicular stomatitis virus onto antigen-specific T cells enhances the efficacy of adoptive T-cell therapy of tumors

(2008) J Qiao et al.   GENE THERAPY

Synergistic antitumor effects of transarterial viroembolization for multifocal hepatocellular carcinoma in rats

(2008) Jennifer Altomonte et al.   HEPATOLOGY

rVSV(MΔ51)-M3 Is an Effective and Safe Oncolytic Virus for Cancer Therapy

(2008) Lan Wu et al.   HUMAN GENE THERAPY

Characterization of retinoic acid–inducible gene-I expression in primary murine glia following exposure to vesicular stomatitis virus

(2008) Samantha R Furr et al.   JOURNAL OF NEUROVIROLOGY

Targeting the Apoptotic Pathway with BCL-2 Inhibitors Sensitizes Primary Chronic Lymphocytic Leukemia Cells to Vesicular Stomatitis Virus-Induced Oncolysis

(2008) V. F. Tumilasci et al.   JOURNAL OF VIROLOGY

The p14 FAST Protein of Reptilian Reovirus Increases Vesicular Stomatitis Virus Neuropathogenesis

(2008) C. W. Brown et al.   JOURNAL OF VIROLOGY

Vesicular Stomatitis Virus Oncolysis of T Lymphocytes Requires Cell Cycle Entry and Translation Initiation

(2008) S. Oliere et al.   JOURNAL OF VIROLOGY

Apoptotic pathways in pancreatic ductal adenocarcinoma

(2008) Rainer Hamacher et al.   Molecular Cancer

Treg Depletion–enhanced IL-2 Treatment Facilitates Therapy of Established Tumors Using Systemically Delivered Oncolytic Virus

(2008) Timothy Kottke et al.   MOLECULAR THERAPY

Use of Biological Therapy to Enhance Both Virotherapy and Adoptive T-Cell Therapy for Cancer

(2008) Timothy Kottke et al.   MOLECULAR THERAPY

Inhibition of the IFN-β Response in Hepatocellular Carcinoma by Alternative Spliced Isoform of IFN Regulatory Factor-3

(2008) Sabrina Marozin et al.   MOLECULAR THERAPY

A let-7 MicroRNA-sensitive Vesicular Stomatitis Virus Demonstrates Tumor-specific Replication

(2008) Robert E Edge et al.   MOLECULAR THERAPY

Chemical targeting of the innate antiviral response by histone deacetylase inhibitors renders refractory cancers sensitive to viral oncolysis

(2008) T. L.-A. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exponential Enhancement of Oncolytic Vesicular Stomatitis Virus Potency by Vector-mediated Suppression of Inflammatory Responses In Vivo

(2007) Jennifer Altomonte et al.   MOLECULAR THERAPY