Energy and Dynamics of Caveolae Trafficking

Keeping in touch with the membrane; protein- and lipid-mediated confinement of caveolae to the cell surface

(2020) Madlen Hubert et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The caveolar-mitochondrial interface: regulation of cellular metabolism in physiology and pathophysiology

(2020) Cerrone R. Foster et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Caveolae and lipid sorting: Shaping the cellular response to stress

(2020) Robert G. Parton et al.   JOURNAL OF CELL BIOLOGY

Caveolae in CNS arterioles mediate neurovascular coupling

(2020) Brian W. Chow et al.   NATURE

Age attenuates the T‐type Ca V 3.2‐RyR axis in vascular smooth muscle

(2020) Gang Fan et al.   AGING CELL

Non-caveolar caveolins – duties outside the caves

(2020) Albert Pol et al.   JOURNAL OF CELL SCIENCE

EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake

(2020) Claudia Matthaeus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular functions and intrinsic attributes of the ATP ‐binding Eps15 homology domain‐containing proteins

(2020) Soumya Bhattacharyya et al.   PROTEIN SCIENCE

Multifaceted Functions of Host Cell Caveolae/Caveolin-1 in Virus Infections

(2020) Yifan Xing et al.   Viruses-Basel

The Na/K-ATPase α1 and c-Src form signaling complex under native condition: A crosslinking approach

(2020) Ying Nie et al.   Scientific Reports

Lipid accumulation controls the balance between surface connection and scission of caveolae

(2020) Madlen Hubert et al.   eLife

Caveolae: Formation, dynamics, and function

(2020) Robert G. Parton et al.   CURRENT OPINION IN CELL BIOLOGY

Coupling of melanocyte signaling and mechanics by caveolae is required for human skin pigmentation

(2020) Lia Domingues et al.   Nature Communications

CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis

(2020) Jian-Wei Hao et al.   Nature Communications

Caveolae: Mechanosensing and mechanotransduction devices linking membrane trafficking to mechanoadaptation

(2020) Miguel A. Del Pozo et al.   CURRENT OPINION IN CELL BIOLOGY

Membrane Curvature and Tension Control the Formation and Collapse of Caveolar Superstructures

(2019) Gonen Golani et al.   DEVELOPMENTAL CELL

EHD2 regulates adipocyte function and is enriched at cell surface-associated lipid droplets in primary human adipocytes

(2019) Björn Morén et al.   MOLECULAR BIOLOGY OF THE CELL

Directed Evolution of Split APEX2 Peroxidase

(2019) Yisu Han et al.   ACS Chemical Biology

Lipid droplet–membrane contact sites – from protein binding to function

(2019) Abdou Rachid Thiam et al.   JOURNAL OF CELL SCIENCE

A primer on resolving the nanoscale structure of the plasma membrane with light and electron microscopy

(2019) Justin W. Taraska   JOURNAL OF GENERAL PHYSIOLOGY

Dystrophy-associated caveolin-3 mutations reveal that caveolae couple IL6/STAT3 signaling with mechanosensing in human muscle cells

(2019) Melissa Dewulf et al.   Nature Communications

Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis

(2019) Kerrie-Ann McMahon et al.   Nature Communications

Secondary structure of caveolins: a mini review

(2019) Kyle T. Root et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Caveolae: The FAQs

(2019) Robert G. Parton et al.   TRAFFIC

eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization

(2019) Claudia Matthaeus et al.   PLoS One

Synaptotagmin‐11 regulates the functions of caveolae and responds to mechanical stimuli in astrocytes

(2019) Shuxin Yan et al.   FASEB JOURNAL

An Abl-FBP17 mechanosensing system couples local plasma membrane curvature and stress fiber remodeling during mechanoadaptation

(2019) Asier Echarri et al.   Nature Communications

Caveolae

(2018) Robert G. Parton et al.   CURRENT BIOLOGY

Caveolin-1, cancer and therapy resistance

(2018) Julia Ketteler et al.   INTERNATIONAL JOURNAL OF CANCER

Effect of hypoxia on caveolae-related protein expression and insulin signaling in adipocytes

(2018) M. Varela-Guruceaga et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Small GTPases and BAR domain proteins regulate branched actin polymerisation for clathrin and dynamin-independent endocytosis

(2018) Mugdha Sathe et al.   Nature Communications

Super Resolution Network Analysis Defines the Molecular Architecture of Caveolae and Caveolin-1 Scaffolds

(2018) Ismail M. Khater et al.   Scientific Reports

Caveolin-1 impairs PKA-DRP1-mediated remodelling of ER–mitochondria communication during the early phase of ER stress

(2018) Roberto Bravo-Sagua et al.   CELL DEATH AND DIFFERENTIATION

Cryo-EM of the dynamin polymer assembled on lipid membrane

(2018) Leopold Kong et al.   NATURE

EHD2 is a mechanotransducer connecting caveolae dynamics with gene transcription

(2018) Stéphanie Torrino et al.   JOURNAL OF CELL BIOLOGY

Dynamics and functions of lipid droplets

(2018) James A. Olzmann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ATP-dependent membrane remodeling links EHD1 functions to endocytic recycling

(2018) Raunaq Deo et al.   Nature Communications

EHD2 restrains dynamics of caveolae by an ATP-dependent, membrane-bound, open conformation

(2017) Maria Hoernke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insights into the activation mechanism of dynamin-like EHD ATPases

(2017) Arthur Alves Melo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deciphering caveolar functions by syndapin III KO-mediated impairment of caveolar invagination

(2017) Eric Seemann et al.   eLife

Measurement of caveolin-1 densities in the cell membrane for quantification of caveolar deformation after exposure to hypotonic membrane tension

(2017) Masashi Tachikawa et al.   Scientific Reports

Invited review: Mechanisms of GTP hydrolysis and conformational transitions in the dynamin superfamily

(2016) Oliver Daumke et al.   BIOPOLYMERS

Membrane fission by dynamin: what we know and what we need to know

(2016) Bruno Antonny et al.   EMBO JOURNAL

Do Src Kinase and Caveolin Interact Directly with Na,K-ATPase?

(2016) Eliyahu Yosef et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Architecture of the caveolar coat complex

(2016) Alexander Ludwig et al.   JOURNAL OF CELL SCIENCE

Model for the architecture of caveolae based on a flexible, net-like assembly of Cavin1 and Caveolin discs

(2016) Miriam Stoeber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of a caveolin-1 mutation associated with both pulmonary arterial hypertension and congenital generalized lipodystrophy

(2016) Bing Han et al.   TRAFFIC

Caveolae: One Function or Many?

(2016) Jade P.X. Cheng et al.   TRENDS IN CELL BIOLOGY

Targeting Fat: Mechanisms of Protein Localization to Lipid Droplets

(2016) Nora Kory et al.   TRENDS IN CELL BIOLOGY

Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells

(2016) E. Bourseau-Guilmain et al.   Nature Communications

PTRF/Cavin-1 promotes efficient ribosomal RNA transcription in response to metabolic challenges

(2016) Libin Liu et al.   eLife

A novel Rab10-EHBP1-EHD2 complex essential for the autophagic engulfment of lipid droplets

(2016) Z. Li et al.   Science Advances

Internalization of the TGF-β type I receptor into caveolin-1 and EEA1 double-positive early endosomes

(2015) Kangmin He et al.   CELL RESEARCH

Hypoxia Inhibits Cavin-1 and Cavin-2 Expression and Down-Regulates Caveolae in Adipocytes

(2015) Claire Regazzetti et al.   ENDOCRINOLOGY

Molecular Characterization of Caveolin-induced Membrane Curvature

(2015) Nicholas Ariotti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caveolae protect endothelial cells from membrane rupture during increased cardiac output

(2015) Jade P.X. Cheng et al.   JOURNAL OF CELL BIOLOGY

Phosphorylation of PACSIN2 by protein kinase C triggers the removal of caveolae from the plasma membrane

(2015) Y. Senju et al.   JOURNAL OF CELL SCIENCE

Caveolae - mechanosensitive membrane invaginations linked to actin filaments

(2015) A. Echarri et al.   JOURNAL OF CELL SCIENCE

Cavin family proteins and the assembly of caveolae

(2015) O. Kovtun et al.   JOURNAL OF CELL SCIENCE

Single-molecule microscopy of molecules tagged with GFP or RFP derivatives in mammalian cells using nanobody binders

(2015) Evgenia Platonova et al.   METHODS

Identification of Caveolar Resident Proteins in Ventricular Myocytes Using a Quantitative Proteomic Approach: Dynamic Changes in Caveolar Composition Following Adrenoceptor Activation

(2015) Krzysztof J. Wypijewski et al.   MOLECULAR & CELLULAR PROTEOMICS

A Frame-Shift Mutation in CAV1 Is Associated with a Severe Neonatal Progeroid and Lipodystrophy Syndrome

(2015) Isabelle Schrauwen et al.   PLoS One

Dynamic caveolae exclude bulk membrane proteins and are required for sorting of excess glycosphingolipids

(2015) Elena Shvets et al.   Nature Communications

Direct interaction of actin filaments with F-BAR protein pacsin2

(2014) J. Kostan et al.   EMBO REPORTS

Actin and dynamin2 dynamics and interplay during clathrin-mediated endocytosis

(2014) Alexandre Grassart et al.   JOURNAL OF CELL BIOLOGY

Hypoxia-Inducible Factor/MAZ-Dependent Induction of Caveolin-1 Regulates Colon Permeability through Suppression of Occludin, Leading to Hypoxia-Induced Inflammation

(2014) Liwei Xie et al.   MOLECULAR AND CELLULAR BIOLOGY

Structural Insights into Membrane Interaction and Caveolar Targeting of Dynamin-like EHD2

(2014) Claudio Shah et al.   STRUCTURE

Clathrin-Independent Pathways of Endocytosis

(2014) S. Mayor et al.   Cold Spring Harbor Perspectives in Biology

Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae

(2014) Yann Gambin et al.   eLife

Potential of caveolae in the therapy of cardiovascular and neurological diseases

(2014) Gemma Navarro et al.   Frontiers in Physiology

Viral Membrane Scission

(2013) Jeremy S. Rossman et al.   Annual Review of Cell and Developmental Biology

Caveolae as plasma membrane sensors, protectors and organizers

(2013) Robert G. Parton et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Deletion of cavin genes reveals tissue-specific mechanisms for morphogenesis of endothelial caveolae

(2013) Carsten Gram Hansen et al.   Nature Communications

Molecular Composition and Ultrastructure of the Caveolar Coat Complex

(2013) Alexander Ludwig et al.   PLOS BIOLOGY

EHD2 shuttles to the nucleus and represses transcription

(2012) Olga Pekar et al.   BIOCHEMICAL JOURNAL

Membrane Shape at the Edge of the Dynamin Helix Sets Location and Duration of the Fission Reaction

(2012) Sandrine Morlot et al.   CELL

Oligomers of the ATPase EHD2 confine caveolae to the plasma membrane through association with actin

(2012) Miriam Stoeber et al.   EMBO JOURNAL

Mitochondria-localized caveolin in adaptation to cellular stress and injury

(2012) Heidi N. Fridolfsson et al.   FASEB JOURNAL

Endothelin Induces Rapid, Dynamin-mediated Budding of Endothelial Caveolae Rich in ET-B

(2012) Phil Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caveolar domain organization and trafficking is regulated by Abl kinases and mDia1

(2012) A. Echarri et al.   JOURNAL OF CELL SCIENCE

EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization

(2012) Björn Morén et al.   MOLECULAR BIOLOGY OF THE CELL

Dynamin, a membrane-remodelling GTPase

(2012) Shawn M. Ferguson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1

(2012) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The phospholipid monolayer associated with perilipin-enriched lipid droplets is a highly organized rigid membrane structure

(2011) Stephen M. Storey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cells Respond to Mechanical Stress by Rapid Disassembly of Caveolae

(2011) Bidisha Sinha et al.   CELL

Caveolae and lipid trafficking in adipocytes

(2011) Paul F Pilch et al.   Clinical Lipidology

Nitric oxide synthases: regulation and function

(2011) U. Forstermann et al.   EUROPEAN HEART JOURNAL

Coordinated regulation of caveolin-1 and Rab11a in apical recycling compartments of polarized epithelial cells

(2011) Lynne A. Lapierre et al.   EXPERIMENTAL CELL RESEARCH

Pacsin 2 is recruited to caveolae and functions in caveolar biogenesis

(2011) C. G. Hansen et al.   JOURNAL OF CELL SCIENCE

Essential role of PACSIN2/syndapin-II in caveolae membrane sculpting

(2011) Y. Senju et al.   JOURNAL OF CELL SCIENCE

Redistribution of caveolae during mitosis

(2011) E. Boucrot et al.   JOURNAL OF CELL SCIENCE

Regulation of Synaptic Vesicle Budding and Dynamin Function by an EHD ATPase

(2011) J. Jakobsson et al.   JOURNAL OF NEUROSCIENCE

Crystal structure of nucleotide-free dynamin

(2011) Katja Faelber et al.   NATURE

Fat caves: caveolae, lipid trafficking and lipid metabolism in adipocytes

(2011) Paul F. Pilch et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Revisiting caveolin trafficking: the end of the caveosome: Figure 1.

(2010) Robert G. Parton et al.   JOURNAL OF CELL BIOLOGY

Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation

(2010) Arnold Hayer et al.   JOURNAL OF CELL BIOLOGY

EHD proteins: key conductors of endocytic transport

(2010) Naava Naslavsky et al.   TRENDS IN CELL BIOLOGY

Caveolinopathies: from the biology of caveolin-3 to human diseases

(2009) Elisabetta Gazzerro et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Endocytosisviacaveolae: alternative pathway with distinct cellular compartments to avoid lysosomal degradation?

(2009) Anna L. Kiss et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects

(2009) Cédric M. Blouin et al.   JOURNAL OF LIPID RESEARCH

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rapid Insulin-Dependent Endocytosis of the Insulin Receptor by Caveolae in Primary Adipocytes

(2009) Siri Fagerholm et al.   PLoS One

Biogenesis of Caveolae: Stepwise Assembly of Large Caveolin and Cavin Complexes

(2009) Arnold Hayer et al.   TRAFFIC

The life of lipid droplets

(2008) Tobias C. Walther et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Caveolae and transcytosis in endothelial cells: role in atherosclerosis

(2008) Philippe G. Frank et al.   CELL AND TISSUE RESEARCH

Regulation of caveolin-1 membrane trafficking by the Na/K-ATPase

(2008) Ting Cai et al.   JOURNAL OF CELL BIOLOGY

Plasma membrane deformation by circular arrays of ESCRT-III protein filaments

(2008) Phyllis I. Hanson et al.   JOURNAL OF CELL BIOLOGY

Caveolin-1 is transported to multi-vesicular bodies after albumin-induced endocytosis of caveolae in HepG2 cells

(2008) E. Botos et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Association of a Homozygous Nonsense Caveolin-1 Mutation with Berardinelli-Seip Congenital Lipodystrophy

(2008) C. A. Kim et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

High-Resolution 3D Quantitative Analysis of Caveolar Ultrastructure and Caveola–Cytoskeleton Interactions

(2008) Tobias Richter et al.   TRAFFIC