EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake

EHD2 regulates adipocyte function and is enriched at cell surface-associated lipid droplets in primary human adipocytes

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Animal models of obesity and diabetes mellitus

(2018) Maximilian Kleinert et al.   Nature Reviews Endocrinology

EHD2 is a mechanotransducer connecting caveolae dynamics with gene transcription

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EHD2 restrains dynamics of caveolae by an ATP-dependent, membrane-bound, open conformation

(2017) Maria Hoernke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insights into the activation mechanism of dynamin-like EHD ATPases

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Deciphering caveolar functions by syndapin III KO-mediated impairment of caveolar invagination

(2017) Eric Seemann et al.   eLife

Obesity is associated with depot-specific alterations in adipocyte DNA methylation and gene expression

(2017) Si Brask Sonne et al.   Adipocyte

Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk

(2016) Jennifer H. Stern et al.   Cell Metabolism

Architecture of the caveolar coat complex

(2016) Alexander Ludwig et al.   JOURNAL OF CELL SCIENCE

Bone morphogenetic protein 2 (BMP2 ) may contribute to partition of energy storage into visceral and subcutaneous fat depots

(2016) Esther Guiu-Jurado et al.   Obesity

Model for the architecture of caveolae based on a flexible, net-like assembly of Cavin1 and Caveolin discs

(2016) Miriam Stoeber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caveolae: One Function or Many?

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A novel Rab10-EHBP1-EHD2 complex essential for the autophagic engulfment of lipid droplets

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Downregulation of de Novo Fatty Acid Synthesis in Subcutaneous Adipose Tissue of Moderately Obese Women

(2015) Esther Guiu-Jurado et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The cell biology of fat expansion

(2015) Joseph M. Rutkowski et al.   JOURNAL OF CELL BIOLOGY

Cavin3 interacts with cavin1 and caveolin1 to increase surface dynamics of caveolae

(2015) J. Mohan et al.   JOURNAL OF CELL SCIENCE

Cavin family proteins and the assembly of caveolae

(2015) O. Kovtun et al.   JOURNAL OF CELL SCIENCE

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Dynamic caveolae exclude bulk membrane proteins and are required for sorting of excess glycosphingolipids

(2015) Elena Shvets et al.   Nature Communications

De novo lipogenesis in metabolic homeostasis: More friend than foe?

(2015) Giovanni Solinas et al.   Molecular Metabolism

Caveolin-1 Expression and Cavin Stability Regulate Caveolae Dynamics in Adipocyte Lipid Store Fluctuation

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Pleiotropic Effects of Cavin-1 Deficiency on Lipid Metabolism

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Structural Insights into Membrane Interaction and Caveolar Targeting of Dynamin-like EHD2

(2014) Claudio Shah et al.   STRUCTURE

PPARγ and the global map of adipogenesis and beyond

(2014) Martina I. Lefterova et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Triacylglycerol Synthesis Enzymes Mediate Lipid Droplet Growth by Relocalizing from the ER to Lipid Droplets

(2013) Florian Wilfling et al.   DEVELOPMENTAL CELL

De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health

(2013) Leah Eissing et al.   Nature Communications

Molecular Composition and Ultrastructure of the Caveolar Coat Complex

(2013) Alexander Ludwig et al.   PLOS BIOLOGY

Oligomers of the ATPase EHD2 confine caveolae to the plasma membrane through association with actin

(2012) Miriam Stoeber et al.   EMBO JOURNAL

EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization

(2012) Björn Morén et al.   MOLECULAR BIOLOGY OF THE CELL

Caveolin-1 Deficiency Leads to Increased Susceptibility to Cell Death and Fibrosis in White Adipose Tissue: Characterization of a Lipodystrophic Model

(2012) Sally Martin et al.   PLoS One

PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation

(2011) Tamas Varga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cells Respond to Mechanical Stress by Rapid Disassembly of Caveolae

(2011) Bidisha Sinha et al.   CELL

Caveolae and lipid trafficking in adipocytes

(2011) Paul F Pilch et al.   Clinical Lipidology

Pacsin 2 is recruited to caveolae and functions in caveolar biogenesis

(2011) C. G. Hansen et al.   JOURNAL OF CELL SCIENCE

Essential role of PACSIN2/syndapin-II in caveolae membrane sculpting

(2011) Y. Senju et al.   JOURNAL OF CELL SCIENCE

Transcriptional factors that promote formation of white adipose tissue

(2009) Ursula A. White et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

PTRF-Cavin, a Conserved Cytoplasmic Protein Required for Caveola Formation and Function

(2008) Michelle M. Hill et al.   CELL

Deletion of Cavin/PTRF Causes Global Loss of Caveolae, Dyslipidemia, and Glucose Intolerance

(2008) Libin Liu et al.   Cell Metabolism