- Home
- Publications
- Publication Search
- Publication Details
Title
Extracellular Citrate Fuels Cancer Cell Metabolism and Growth
Authors
Keywords
-
Journal
Frontiers in Cell and Developmental Biology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-12-04
DOI
10.3389/fcell.2020.602476
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Lactic acid promotes macrophage polarization through MCT-HIF1α signaling in gastric cancer
- (2020) Lan Zhang et al. EXPERIMENTAL CELL RESEARCH
- The lactate receptor GPR81 promotes breast cancer growth via a paracrine mechanism involving antigen-presenting cells in the tumor microenvironment
- (2020) Timothy P. Brown et al. ONCOGENE
- Chronic exposure to excess iron promotes EMT and cancer via p53 loss in pancreatic cancer
- (2020) Yangzom D. Bhutia et al. Asian Journal of Pharmaceutical Sciences
- The Hepatic Plasma Membrane Citrate Transporter NaCT (SLC13A5) as a Molecular Target for Metformin
- (2020) Jonathan Kopel et al. Scientific Reports
- Altered Iron Metabolism and Impact in Cancer Biology, Metastasis, and Immunology
- (2020) Rikki A. M. Brown et al. Frontiers in Oncology
- Enhanced glutamine utilization mediated by SLC1A5 and GPT2 is an essential metabolic feature of colorectal signet ring cell carcinoma with therapeutic potential
- (2020) Renjie Wang et al. Annals of Translational Medicine
- The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP
- (2020) Flora Szeri et al. PLoS Genetics
- Hereditary hemochromatosis promotes colitis and colon cancer and causes bacterial dysbiosis in mice
- (2020) Sathish Sivaprakasam et al. BIOCHEMICAL JOURNAL
- Functional Distinction between Human and Mouse Sodium-Coupled Citrate Transporters and Its Biologic Significance: An Attempt for Structural Basis Using a Homology Modeling Approach
- (2020) Valeria Jaramillo-Martinez et al. CHEMICAL REVIEWS
- Iron as a Central Player and Promising Target in Cancer Progression
- (2019) Michaela Jung et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Breast cancer cells rely on environmental pyruvate to shape the metastatic niche
- (2019) Ilaria Elia et al. NATURE
- Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer
- (2019) Luigi Ippolito et al. ONCOGENE
- Fibroblasts as Modulators of Local and Systemic Cancer Metabolism
- (2019) Hannah Sanford-Crane et al. Cancers
- Metabolic reprogramming of normal oral fibroblasts correlated with increased glycolytic metabolism of oral squamous cell carcinoma and precedes their activation into carcinoma associated fibroblasts
- (2019) Zhuoyuan Zhang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Potential Use of Gluconate in Cancer Therapy
- (2019) Maria E. Mycielska et al. Frontiers in Oncology
- Mitochondrial Carriers for Aspartate, Glutamate and Other Amino Acids: A Review
- (2019) Magnus Monné et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Ferroportin downregulation promotes cell proliferation by modulating the Nrf2–miR-17-5p axis in multiple myeloma
- (2019) Yuanyuan Kong et al. Cell Death & Disease
- Metabolic heterogeneity confers differences in melanoma metastatic potential
- (2019) Alpaslan Tasdogan et al. NATURE
- Lactate/GPR81 signaling and proton motive force in cancer: Role in angiogenesis, immune escape, nutrition, and Warburg phenomenon
- (2019) Timothy P. Brown et al. PHARMACOLOGY & THERAPEUTICS
- Extracellular Citrate Affects Critical Elements of Cancer Cell Metabolism and Supports Cancer DevelopmentIn Vivo
- (2018) Maria E. Mycielska et al. CANCER RESEARCH
- The mitochondrial citrate carrier, SLC25A1, drives stemness and therapy resistance in non-small cell lung cancer
- (2018) Harvey R. Fernandez et al. CELL DEATH AND DIFFERENTIATION
- The longevity gene INDY ( I 'm N ot D ead Y et) in metabolic control: Potential as pharmacological target
- (2018) Diana M. Willmes et al. PHARMACOLOGY & THERAPEUTICS
- The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading
- (2018) Anna Baulies et al. Redox Biology
- The Mitochondrial Citrate Carrier (SLC25A1) Sustains Redox Homeostasis and Mitochondrial Metabolism Supporting Radioresistance of Cancer Cells With Tolerance to Cycling Severe Hypoxia
- (2018) Julian Hlouschek et al. Frontiers in Oncology
- Extracellular Citrate and Cancer Metabolism—Response
- (2018) Maria E. Mycielska et al. CANCER RESEARCH
- Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting
- (2018) H. Furkan Alkan et al. Cell Metabolism
- The induction of the fibroblast extracellular senescence metabolome is a dynamic process
- (2018) Emma N. L. James et al. Scientific Reports
- Epigenetic upregulation and functional role of the mitochondrial aspartate/glutamate carrier isoform 1 in hepatocellular carcinoma
- (2018) Vittoria Infantino et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Pyruvate secreted from patient-derived cancer-associated fibroblasts supports survival of primary lymphoma cells
- (2018) Akihiko Sakamoto et al. CANCER SCIENCE
- Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy
- (2018) Thomas Bertero et al. Cell Metabolism
- Iron Metabolism in Cancer
- (2018) Yafang Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Ovarian Cancer Relies on Glucose Transporter 1 to Fuel Glycolysis and Growth: Anti-Tumor Activity of BAY-876
- (2018) Yibao Ma et al. Cancers
- Clinical penetrance in hereditary hemochromatosis: estimates of the cumulative incidence of severe liver disease among HFE C282Y homozygotes
- (2017) Scott D Grosse et al. GENETICS IN MEDICINE
- Flipping a citrate switch on liver cancer cells
- (2017) Jeffrey M. Peters JOURNAL OF BIOLOGICAL CHEMISTRY
- Silencing of solute carrier family 13 member 5 disrupts energy homeostasis and inhibits proliferation of human hepatocarcinoma cells
- (2017) Zhihui Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Plasma Membrane Na+-Coupled Citrate Transporter (SLC13A5) and Neonatal Epileptic Encephalopathy
- (2017) Yangzom Bhutia et al. MOLECULES
- Diagnosis of prostate cancer by desorption electrospray ionization mass spectrometric imaging of small metabolites and lipids
- (2017) Shibdas Banerjee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transferrin receptor 1 upregulation in primary tumor and downregulation in benign kidney is associated with progression and mortality in renal cell carcinoma patients
- (2017) Christopher J. Greene et al. Oncotarget
- Induction of fibroblast senescence generates a non-fibrogenic myofibroblast phenotype that differentially impacts on cancer prognosis
- (2016) Massimiliano Mellone et al. Aging-US
- Glutamine transporters in mammalian cells and their functions in physiology and cancer
- (2016) Yangzom D. Bhutia et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis
- (2016) Xiang Xue et al. Cell Metabolism
- From Ancient Pathways to Aging Cells—Connecting Metabolism and Cellular Senescence
- (2016) Christopher D. Wiley et al. Cell Metabolism
- Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer
- (2016) Shawn M. Davidson et al. Cell Metabolism
- Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
- (2016) Cristovão M. Sousa et al. NATURE
- Replicatively senescent human fibroblasts reveal a distinct intracellular metabolic profile with alterations in NAD+ and nicotinamide metabolism
- (2016) Emma L. James et al. Scientific Reports
- Amino Acid Transporters in Cancer and Their Relevance to "Glutamine Addiction": Novel Targets for the Design of a New Class of Anticancer Drugs
- (2015) Y. D. Bhutia et al. CANCER RESEARCH
- Extracellular Citrate in Health and Disease
- (2015) M. Mycielska et al. CURRENT MOLECULAR MEDICINE
- The acetyl-CoA carboxylase enzyme: a target for cancer therapy?
- (2015) Chao Wang et al. Expert Review of Anticancer Therapy
- Cytosolic aconitase activity sustains adipogenic capacity of adipose tissue connecting iron metabolism and adipogenesis
- (2015) María Moreno et al. FASEB JOURNAL
- Senescent Human Fibroblasts Show Increased Glycolysis and Redox Homeostasis with Extracellular Metabolomes That Overlap with Those of Irreparable DNA Damage, Aging, and Disease
- (2015) Emma L. James et al. JOURNAL OF PROTEOME RESEARCH
- PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth
- (2015) Emily D. Montal et al. MOLECULAR CELL
- Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth
- (2015) Emma E. Vincent et al. MOLECULAR CELL
- The mitochondrial citrate transporter, CIC, is essential for mitochondrial homeostasis.
- (2015) Olga Catalina-Rodriguez et al. Oncotarget
- SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker.
- (2015) Vamsi K. Kolukula et al. Oncotarget
- Metabolic Reprogramming of Stromal Fibroblasts through p62-mTORC1 Signaling Promotes Inflammation and Tumorigenesis
- (2014) Tania Valencia et al. CANCER CELL
- Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth
- (2014) Ubaldo E. Martinez-Outschoorn et al. SEMINARS IN CANCER BIOLOGY
- The pentose phosphate pathway and cancer
- (2014) Krushna C. Patra et al. TRENDS IN BIOCHEMICAL SCIENCES
- Oxidation of Alpha-Ketoglutarate Is Required for Reductive Carboxylation in Cancer Cells with Mitochondrial Defects
- (2014) Andrew R. Mullen et al. Cell Reports
- Physiological and pathological roles of mitochondrial SLC25 carriers: Figure 1
- (2013) Manuel Gutiérrez-Aguilar et al. BIOCHEMICAL JOURNAL
- Identification of Two Distinct Carcinoma-Associated Fibroblast Subtypes with Differential Tumor-Promoting Abilities in Oral Squamous Cell Carcinoma
- (2013) Daniela Elena Costea et al. CANCER RESEARCH
- Progression of genotype-specific oral cancer leads to senescence of cancer-associated fibroblasts and is mediated by oxidative stress and TGF-β
- (2013) Yazan Hassona et al. CARCINOGENESIS
- Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth
- (2012) Taro Hitosugi et al. CANCER CELL
- Analysis of Tumor Metabolism Reveals Mitochondrial Glucose Oxidation in Genetically Diverse Human Glioblastomas in the Mouse Brain In Vivo
- (2012) Isaac Marin-Valencia et al. Cell Metabolism
- Deletion of the Mammalian INDY Homolog Mimics Aspects of Dietary Restriction and Protects against Adiposity and Insulin Resistance in Mice
- (2011) Andreas L. Birkenfeld et al. Cell Metabolism
- Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
- (2011) Richard Possemato et al. NATURE
- Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
- (2011) Christian M. Metallo et al. NATURE
- Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
- (2011) Jason W Locasale et al. NATURE GENETICS
- Fructose Induces Transketolase Flux to Promote Pancreatic Cancer Growth
- (2010) H. Liu et al. CANCER RESEARCH
- Molecular origin of plasma membrane citrate transporter in human prostate epithelial cells
- (2010) Maciej P Mazurek et al. EMBO REPORTS
- Fibroblast gene expression profile reflects the stage of tumour progression in oral squamous cell carcinoma
- (2010) Kue Peng Lim et al. JOURNAL OF PATHOLOGY
- Senescent mesenchymal cells accumulate in human fibrosis by a telomere-independent mechanism and ameliorate fibrosis through matrix metalloproteinases
- (2010) Gayani Nadika Pitiyage et al. JOURNAL OF PATHOLOGY
- Citrate transport and metabolism in mammalian cells
- (2009) Maria E. Mycielska et al. BIOESSAYS
- ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
- (2009) K. E. Wellen et al. SCIENCE
- Insights on Regulation and Function of the Iron Regulatory Protein 1 (IRP1)
- (2008) Jian Wang et al. HEMOGLOBIN
- Nutrient transporters in cancer: Relevance to Warburg hypothesis and beyond
- (2008) Vadivel Ganapathy et al. PHARMACOLOGY & THERAPEUTICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started