The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP

High-fructose corn syrup enhances intestinal tumor growth in mice

(2019) Marcus D. Goncalves et al.   SCIENCE

Urine citrate excretion as a marker of acid retention in patients with chronic kidney disease without overt metabolic acidosis

(2019) Nimrit Goraya et al.   KIDNEY INTERNATIONAL

Extracellular Citrate Affects Critical Elements of Cancer Cell Metabolism and Supports Cancer DevelopmentIn Vivo

(2018) Maria E. Mycielska et al.   CANCER RESEARCH

The effect of thiazide and potassium citrate use on the health-related quality of life of patients with urolithiasis

(2018) Eric P. Raffin et al.   JOURNAL OF UROLOGY

Citrate-based materials fuel human stem cells by metabonegenic regulation

(2018) Chuying Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PXE, a Mysterious Inborn Error Clarified

(2018) Piet Borst et al.   TRENDS IN BIOCHEMICAL SCIENCES

Insights into Pathomechanisms and Treatment Development in Heritable Ectopic Mineralization Disorders: Summary of the PXE International Biennial Research Symposium—2016

(2017) Jouni Uitto et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Inherited Arterial Calcification Syndromes: Etiologies and Treatment Concepts

(2017) Yvonne Nitschke et al.   Current Osteoporosis Reports

Pyrophosphate: a key inhibitor of mineralisation

(2016) Isabel R Orriss et al.   CURRENT OPINION IN PHARMACOLOGY

The Role of ANK in Calcium Pyrophosphate Deposition Disease

(2016) Elizabeth Mitton-Fitzgerald et al.   Current Rheumatology Reports

Extracellular Citrate in Health and Disease

(2015) M. Mycielska et al.   CURRENT MOLECULAR MEDICINE

Effects of etidronate on the Enpp1−/− mouse model of generalized arterial calcification of infancy

(2015) CARMEN HUESA et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

ENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancy

(2015) Ronald A. Albright et al.   Nature Communications

ABCC6–Mediated ATP Secretion by the Liver Is the Main Source of the Mineralization Inhibitor Inorganic Pyrophosphate in the Systemic Circulation—Brief Report

(2014) Robert S. Jansen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Citrate – new functions for an old metabolite

(2014) Vito Iacobazzi et al.   BIOLOGICAL CHEMISTRY

An atlas of genetic influences on human blood metabolites

(2014) So-Youn Shin et al.   NATURE GENETICS

Mutant Enpp1asj mice as a model for generalized arterial calcification of infancy

(2013) Q. Li et al.   Disease Models & Mechanisms

Correlations between Milk and Plasma Levels of Amino and Carboxylic Acids in Dairy Cows

(2013) Matthias S. Klein et al.   JOURNAL OF PROTEOME RESEARCH

Sodium-coupled dicarboxylate and citrate transporters from the SLC13 family

(2013) Ana M. Pajor   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release

(2013) R. S. Jansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The progressive ankylosis gene product ANK regulates extracellular ATP levels in primary articular chondrocytes

(2013) Ann K Rosenthal et al.   ARTHRITIS RESEARCH & THERAPY

Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling

(2012) K. Kato et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletion of the Mammalian INDY Homolog Mimics Aspects of Dietary Restriction and Protects against Adiposity and Insulin Resistance in Mice

(2011) Andreas L. Birkenfeld et al.   Cell Metabolism

Parallel regulation of extracellular ATP and inorganic pyrophosphate: Roles of growth factors, transduction modulators, and ANK

(2010) Jill C. Costello et al.   CONNECTIVE TISSUE RESEARCH

Molecular origin of plasma membrane citrate transporter in human prostate epithelial cells

(2010) Maciej P Mazurek et al.   EMBO REPORTS

Progressive ankylosis protein (ANK) in osteoblasts and osteoclasts controls bone formation and bone remodeling

(2010) Hyon Jong Kim et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

(2010) Mary L Bouxsein et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Autosomal Recessive Mental Retardation, Deafness, Ankylosis, and Mild Hypophosphatemia Associated with a NovelANKHMutation in a Consanguineous Family

(2010) Eva Morava et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Pathophysiology of articular chondrocalcinosis—role of ANKH

(2010) Abhishek Abhishek et al.   Nature Reviews Rheumatology

Strongly bound citrate stabilizes the apatite nanocrystals in bone

(2010) Y.- Y. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomineralization in Humans: Making the Hard Choices in Life

(2009) Kazuhiko Kawasaki et al.   Annual Review of Genetics

Guanidinoacetate methyltransferase (GAMT) deficiency diagnosed by proton NMR spectroscopy of body fluids

(2009) Udo F. H. Engelke et al.   NMR IN BIOMEDICINE