Plasma Membrane Na+-Coupled Citrate Transporter (SLC13A5) and Neonatal Epileptic Encephalopathy

The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism

(2017) Christian von Loeffelholz et al.   HEPATOLOGY

Synaptic Zn2+and febrile seizure susceptibility

(2016) Christopher A Reid et al.   BRITISH JOURNAL OF PHARMACOLOGY

Optimization of a Dicarboxylic Series for in Vivo Inhibition of Citrate Transport by the Solute Carrier 13 (SLC13) Family

(2016) Kim Huard et al.   JOURNAL OF MEDICINAL CHEMISTRY

Aerobic glycolysis during brain activation: adrenergic regulation and influence of norepinephrine on astrocytic metabolism

(2016) Gerald A. Dienel et al.   JOURNAL OF NEUROCHEMISTRY

Mutations in the Na+/Citrate Cotransporter NaCT (SLC13A5) in Pediatric Patients with Epilepsy and Developmental Delay

(2016) Jenna Klotz et al.   MOLECULAR MEDICINE

The interneuron energy hypothesis: Implications for brain disease

(2016) Oliver Kann   NEUROBIOLOGY OF DISEASE

Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain

(2016) Annabel Romero-Hernandez et al.   NEURON

Altered zinc sensitivity of NMDA receptors harboring clinically-relevant mutations

(2016) Benjamin Serraz et al.   NEUROPHARMACOLOGY

Prevention of diet-induced hepatic steatosis and hepatic insulin resistance by second generation antisense oligonucleotides targeted to the longevity gene mIndy (Slc13a5)

(2015) Dominik H. Pesta et al.   Aging-US

Dietary restriction, mitochondrial function and aging: from yeast to humans

(2015) Andrea Ruetenik et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Recessive mutations inSLC13A5result in a loss of citrate transport and cause neonatal epilepsy, developmental delay and teeth hypoplasia

(2015) Katia Hardies et al.   BRAIN

Extracellular Citrate in Health and Disease

(2015) M. Mycielska et al.   CURRENT MOLECULAR MEDICINE

Mitochondrial dysfunction and seizures: the neuronal energy crisis

(2015) Gábor Zsurka et al.   LANCET NEUROLOGY

Arylhydrocarbon receptor-dependent mIndy (Slc13a5) induction as possible contributor to benzo[a]pyrene-induced lipid accumulation in hepatocytes

(2015) Frank Neuschäfer-Rube et al.   TOXICOLOGY

Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5)

(2015) Kim Huard et al.   Scientific Reports

The role of INDY in metabolism, health and longevity

(2015) Ryan P. Rogers et al.   Frontiers in Genetics

Mutations in SLC13A5 Cause Autosomal-Recessive Epileptic Encephalopathy with Seizure Onset in the First Days of Life

(2014) Julien Thevenon et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Citrate – new functions for an old metabolite

(2014) Vito Iacobazzi et al.   BIOLOGICAL CHEMISTRY

Caloric restriction and the aging process: a critique

(2014) Rajindar S. Sohal et al.   FREE RADICAL BIOLOGY AND MEDICINE

A nonequilibrium binary elements-based kinetic model for benzodiazepine regulation of GABAAreceptors

(2014) Marcel P. Goldschen-Ohm et al.   JOURNAL OF GENERAL PHYSIOLOGY

Combined D2-/L2-hydroxyglutaric aciduria (SLC25A1 deficiency): clinical course and effects of citrate treatment

(2014) Chris Mühlhausen et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Focal epilepsy in Glucose transporter type 1 (Glut1) defects: case reports and a review of literature

(2014) Stefan Wolking et al.   JOURNAL OF NEUROLOGY

Zinc Dynamics and Action at Excitatory Synapses

(2014) Angela Maria Vergnano et al.   NEURON

Monocarboxylate transporters in temporal lobe epilepsy: roles of lactate and ketogenic diet

(2013) Fredrik Lauritzen et al.   Brain Structure & Function

The Mammalian INDY Homolog Is Induced by CREB in a Rat Model of Type 2 Diabetes

(2013) F. Neuschafer-Rube et al.   DIABETES

SLC13 family of Na+-coupled di- and tri-carboxylate/sulfate transporters

(2013) M.J. Bergeron et al.   MOLECULAR ASPECTS OF MEDICINE

The SLC16 gene family – Structure, role and regulation in health and disease

(2013) Andrew P. Halestrap   MOLECULAR ASPECTS OF MEDICINE

Glucose transport families SLC5 and SLC50

(2013) Ernest M. Wright   MOLECULAR ASPECTS OF MEDICINE

Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth

(2013) Ruiting Lin et al.   MOLECULAR CELL

THE ROLE OF INDY IN METABOLIC REGULATION

(2013) Diana M Willmes et al.   Computational and Structural Biotechnology Journal

Ketone bodies in epilepsy

(2012) Melanie A. McNally et al.   JOURNAL OF NEUROCHEMISTRY

Energy depletion in seizures: Anaplerosis as a strategy for future therapies

(2012) Stjepana Kovac et al.   NEUROPHARMACOLOGY

Zinc in Neurotransmission

(2011) Katalin Tóth   Annual Review of Nutrition

Zinc Effects on NMDA Receptor Gating Kinetics

(2011) Stacy A. Amico-Ruvio et al.   BIOPHYSICAL JOURNAL

Deletion of the Mammalian INDY Homolog Mimics Aspects of Dietary Restriction and Protects against Adiposity and Insulin Resistance in Mice

(2011) Andreas L. Birkenfeld et al.   Cell Metabolism

Plasma Citrate Levels as a Potential Biomarker for Glaucoma

(2011) Stephan A. Fraenkl et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Sodium-coupled Monocarboxylate Transporters in Normal Tissues and in Cancer

(2008) Vadivel Ganapathy et al.   AAPS Journal

Brain energetics (thought needs food)

(2008) Luc Pellerin   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE