Matrix stiffness epigenetically regulates the oncogenic activation of the Yes-associated protein in gastric cancer

Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility

(2019) Ryan S. Stowers et al.   Nature Biomedical Engineering

Matrix stiffness determines the phenotype of vascular smooth muscle cell in vitro and in vivo : Role of DNA methyltransferase 1

(2018) Si-An Xie et al.   BIOMATERIALS

YAP/TAZ initiates gastric tumorigenesis via upregulation of MYC

(2018) Wonyoung Choi et al.   CANCER RESEARCH

Fibrin Stiffness Mediates Dormancy of Tumor-Repopulating Cells via a Cdc42-Driven Tet2 Epigenetic Program

(2018) Yuying Liu et al.   CANCER RESEARCH

Mechanisms and impact of altered tumour mechanics

(2018) Hamid Mohammadi et al.   NATURE CELL BIOLOGY

YAP/TAZ upstream signals and downstream responses

(2018) Antonio Totaro et al.   NATURE CELL BIOLOGY

Tet2 Rescues Age-Related Regenerative Decline and Enhances Cognitive Function in the Adult Mouse Brain

(2018) Geraldine Gontier et al.   Cell Reports

Increased extracellular matrix density disrupts E-cadherin/β-catenin complex in gastric cancer cells

(2018) Minjeong Jang et al.   Biomaterials Science

Biomaterials and engineered microenvironments to control YAP/TAZ-dependent cell behaviour

(2018) Giovanna Brusatin et al.   NATURE MATERIALS

GENCODE reference annotation for the human and mouse genomes

(2018) Adam Frankish et al.   NUCLEIC ACIDS RESEARCH

TET2 coactivates gene expression through demethylation of enhancers

(2018) Lu Wang et al.   Science Advances

Mechanobiology of YAP and TAZ in physiology and disease

(2017) Tito Panciera et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanical forces direct stem cell behaviour in development and regeneration

(2017) Kyle H. Vining et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

YAP regulates cell mechanics by controlling focal adhesion assembly

(2017) Giorgia Nardone et al.   Nature Communications

Verteporfin inhibits gastric cancer cell growth by suppressing adhesion molecule FAT1

(2017) Myoung-Hee Kang et al.   Oncotarget

Epigenetic regulation of NOTCH1 and NOTCH3 by KMT2A inhibits glioma proliferation

(2017) Yin-Cheng Huang et al.   Oncotarget

Reorganized Collagen in the Tumor Microenvironment of Gastric Cancer and Its Association with Prognosis

(2017) Zhi-Hua Zhou et al.   Journal of Cancer

YAP/TAZ at the Roots of Cancer

(2016) Francesca Zanconato et al.   CANCER CELL

Material Cues as Potent Regulators of Epigenetics and Stem Cell Function

(2016) Spencer W. Crowder et al.   Cell Stem Cell

Integrin-mediated mechanotransduction

(2016) Zhiqi Sun et al.   JOURNAL OF CELL BIOLOGY

Quantitative methylation analysis reveals distinct association between PAX6 methylation and clinical characteristics with different viral infections in hepatocellular carcinoma

(2016) Yu-Lueng Shih et al.   Clinical Epigenetics

Actin remodeling confers BRAF inhibitor resistance to melanoma cells through YAP/TAZ activation

(2015) M. H. Kim et al.   EMBO JOURNAL

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

Biomechanical and biochemical remodeling of stromal extracellular matrix in cancer

(2015) Ruchi Malik et al.   TRENDS IN BIOTECHNOLOGY

YAP and TAZ: a nexus for Hippo signaling and beyond

(2015) Carsten Gram Hansen et al.   TRENDS IN CELL BIOLOGY

Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts

(2015) Jean Albrengues et al.   Nature Communications

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Matrix elasticity, replicative senescence and DNA methylation patterns of mesenchymal stem cells

(2014) Anne Schellenberg et al.   BIOMATERIALS

Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium

(2014) Ovijit Chaudhuri et al.   NATURE MATERIALS

Mechanical memory and dosing influence stem cell fate

(2014) Chun Yang et al.   NATURE MATERIALS

Mechanotransduction and extracellular matrix homeostasis

(2014) Jay D. Humphrey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

Integrative genomics analysis reveals the multilevel dysregulation and oncogenic characteristics of TEAD4 in gastric cancer

(2013) Byungho Lim et al.   CARCINOGENESIS

Dual Roles of the Transcription Factor Grainyhead-like 2 (GRHL2) in Breast Cancer

(2013) Stefan Werner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Yes-Associated Protein 1 Exhibits Oncogenic Property in Gastric Cancer and Its Nuclear Accumulation Associates with Poor Prognosis

(2011) W. Kang et al.   CLINICAL CANCER RESEARCH

DBCAT: Database of CpG Islands and Analytical Tools for Identifying Comprehensive Methylation Profiles in Cancer Cells

(2011) Hsien-Chi Kuo et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Grainyhead-like 2 Enhances the Human Telomerase Reverse Transcriptase Gene Expression by Inhibiting DNA Methylation at the 5′-CpG Island in Normal Human Keratinocytes

(2010) Wei Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting DNA methylation for epigenetic therapy

(2010) Xiaojing Yang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Structure of the MLL CXXC domain–DNA complex and its functional role in MLL-AF9 leukemia

(2009) Tomasz Cierpicki et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA hypomethylation in cancer cells

(2009) Melanie Ehrlich   Epigenomics