TET2 coactivates gene expression through demethylation of enhancers
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
TET2 coactivates gene expression through demethylation of enhancers
Authors
Keywords
-
Journal
Science Advances
Volume 4, Issue 11, Pages eaau6986
Publisher
American Association for the Advancement of Science (AAAS)
Online
2018-11-08
DOI
10.1126/sciadv.aau6986
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- DNA methylation regulates the neonatal CD4+ T-cell response to pneumonia in mice
- (2018) Sharon McGrath-Morrow et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy
- (2018) Lu Wang et al. NATURE MEDICINE
- KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function
- (2018) Kinisha Gala et al. ONCOGENE
- A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism
- (2017) Lu Wang et al. GENES & DEVELOPMENT
- Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation
- (2017) Kristel M. Dorighi et al. MOLECULAR CELL
- Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability
- (2017) Ryan Rickels et al. NATURE GENETICS
- DNA methylation at enhancers identifies distinct breast cancer lineages
- (2017) Thomas Fleischer et al. Nature Communications
- TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities
- (2017) Sara Montagner et al. Cell Reports
- Aging and DNA methylation
- (2015) Marc Jung et al. BMC BIOLOGY
- Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding
- (2015) Shashank Tripathi et al. Cell Host & Microbe
- Loss ofTET2in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis
- (2015) Kasper D. Rasmussen et al. GENES & DEVELOPMENT
- Chromatin signatures of cancer
- (2015) Marc A. Morgan et al. GENES & DEVELOPMENT
- WT1 Recruits TET2 to Regulate Its Target Gene Expression and Suppress Leukemia Cell Proliferation
- (2015) Yiping Wang et al. MOLECULAR CELL
- TET1 is a tumor suppressor of hematopoietic malignancy
- (2015) Luisa Cimmino et al. NATURE IMMUNOLOGY
- DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer
- (2015) Andrew Stone et al. Nature Communications
- TET2 repression by androgen hormone regulates global hydroxymethylation status and prostate cancer progression
- (2015) Ken-ichi Takayama et al. Nature Communications
- HTSeq--a Python framework to work with high-throughput sequencing data
- (2014) S. Anders et al. BIOINFORMATICS
- ngs.plot: Quick mining and visualization of next-generation sequencing data by integrating genomic databases
- (2014) Li Shen et al. BMC GENOMICS
- MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia
- (2014) Chong Chen et al. CANCER CELL
- Effect of estrogen receptor α binding on functional DNA methylation in breast cancer
- (2014) Matthew Ung et al. Epigenetics
- Role of Tet proteins in enhancer activity and telomere elongation
- (2014) Falong Lu et al. GENES & DEVELOPMENT
- 5mC Oxidation by Tet2 Modulates Enhancer Activity and Timing of Transcriptome Reprogramming during Differentiation
- (2014) Gary C. Hon et al. MOLECULAR CELL
- A Bayesian hierarchical model to detect differentially methylated loci from single nucleotide resolution sequencing data
- (2014) Hao Feng et al. NUCLEIC ACIDS RESEARCH
- Genome-wide Analysis Reveals TET- and TDG-Dependent 5-Methylcytosine Oxidation Dynamics
- (2013) Li Shen et al. CELL
- The MLL3/MLL4 Branches of the COMPASS Family Function as Major Histone H3K4 Monomethylases at Enhancers
- (2013) D. Hu et al. MOLECULAR AND CELLULAR BIOLOGY
- Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX
- (2013) Myunggon Ko et al. NATURE
- Mutational landscape and significance across 12 major cancer types
- (2013) Cyriac Kandoth et al. NATURE
- Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4
- (2012) H.-M. Herz et al. GENES & DEVELOPMENT
- Whole-genome analysis informs breast cancer response to aromatase inhibition
- (2012) Matthew J. Ellis et al. NATURE
- TET2 promotes histone O-GlcNAcylation during gene transcription
- (2012) Qiang Chen et al. NATURE
- Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators
- (2012) Akihiro Fujimoto et al. NATURE GENETICS
- Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation
- (2012) H Yang et al. ONCOGENE
- Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
- (2011) M. Ko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
- (2010) Shinsuke Ito et al. NATURE
- GREAT improves functional interpretation of cis-regulatory regions
- (2010) Cory Y McLean et al. NATURE BIOTECHNOLOGY
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients
- (2009) Balazs Györffy et al. BREAST CANCER RESEARCH AND TREATMENT
- Epigenetics in cancer
- (2009) S. Sharma et al. CARCINOGENESIS
- ChIP-Seq of ERα and RNA polymerase II defines genes differentially responding to ligands
- (2009) Willem-Jan Welboren et al. EMBO JOURNAL
- Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
- (2009) M. Tahiliani et al. SCIENCE
- Epigenetics in Cancer
- (2008) Manel Esteller NEW ENGLAND JOURNAL OF MEDICINE
- Model-based Analysis of ChIP-Seq (MACS)
- (2008) Yong Zhang et al. GENOME BIOLOGY
- Cancer Epigenetics: Modifications, Screening, and Therapy
- (2007) Gal-Yam Einav Nili et al. Annual Review of Medicine
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started