Increased extracellular matrix density disrupts E-cadherin/β-catenin complex in gastric cancer cells

FAK controls the mechanical activation of YAP, a transcriptional regulator required for durotaxis

(2018) Dariusz Lachowski et al.   FASEB JOURNAL

Biomechanical and biomolecular characterization of extracellular matrix structures in human colon carcinomas

(2018) Eva Brauchle et al.   MATRIX BIOLOGY

Biomimetic tumor microenvironments based on collagen matrices

(2018) Jiranuwat Sapudom et al.   Biomaterials Science

Sensing the mechano-chemical properties of the extracellular matrix

(2017) Pia Ringer et al.   MATRIX BIOLOGY

Multicellular tumor invasion and plasticity in biomimetic materials

(2017) Susan E. Leggett et al.   Biomaterials Science

Reorganized Collagen in the Tumor Microenvironment of Gastric Cancer and Its Association with Prognosis

(2017) Zhi-Hua Zhou et al.   Journal of Cancer

Matrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells

(2017) A J Rice et al.   Oncogenesis

In vitro cancer cell–ECM interactions inform in vivo cancer treatment

(2016) Andrew W. Holle et al.   ADVANCED DRUG DELIVERY REVIEWS

CD44 alternative splicing in gastric cancer cells is regulated by culture dimensionality and matrix stiffness

(2016) Cristiana Branco da Cunha et al.   BIOMATERIALS

Efficacy of focal adhesion kinase inhibition in non-small cell lung cancer with oncogenically activated MAPK pathways

(2016) Hao Zhang et al.   BRITISH JOURNAL OF CANCER

An integrin beta4-EGFR unit promotes hepatocellular carcinoma lung metastases by enhancing anchorage independence through activation of FAK–AKT pathway

(2016) Chao Leng et al.   CANCER LETTERS

The epithelial–mesenchymal transition (EMT) is regulated by oncoviruses in cancer

(2016) Xue Chen et al.   FASEB JOURNAL

The mechanical regulation of integrin–cadherin crosstalk organizes cells, signaling and forces

(2016) Keeley L. Mui et al.   JOURNAL OF CELL SCIENCE

A polyethylene glycol-based hydrogel as macroporous scaffold for tumorsphere formation of glioblastoma multiforme

(2016) Yoonjee Oh et al.   JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY

Cancer-associated fibroblasts: A multifaceted driver of breast cancer progression

(2015) Haojun Luo et al.   CANCER LETTERS

Lysyl oxidase is associated with the epithelial–mesenchymal transition of gastric cancer cells in hypoxia

(2015) Hiroaki Kasashima et al.   Gastric Cancer

Tunable Collagen I Hydrogels for Engineered Physiological Tissue Micro-Environments

(2015) Elizabeth E. Antoine et al.   PLoS One

The extracellular matrix modulates the hallmarks of cancer

(2014) M. W. Pickup et al.   EMBO REPORTS

Extracellular matrix density promotes EMT by weakening cell–cell adhesions

(2014) Sandeep Kumar et al.   Molecular BioSystems

Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium

(2014) Ovijit Chaudhuri et al.   NATURE MATERIALS

ECM stiffness paves the way for tumor cells

(2014) Victoria Seewaldt   NATURE MEDICINE

At the leading edge of three-dimensional cell migration

(2013) R. J. Petrie et al.   JOURNAL OF CELL SCIENCE

E-cadherin-integrin crosstalk in cancer invasion and metastasis

(2013) M. Canel et al.   JOURNAL OF CELL SCIENCE

Signalling pathways linking integrins with cell cycle progression

(2013) Paulina Moreno-Layseca et al.   MATRIX BIOLOGY

Gastric cancer: adding glycosylation to the equation

(2013) Salomé S. Pinho et al.   TRENDS IN MOLECULAR MEDICINE

Integrins and metastasis

(2013) Kirat Kumar Ganguly et al.   Cell Adhesion & Migration

Microenvironmental Control of the Breast Cancer Cell Cycle

(2012) Xun Guo et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Spatial segregation between cell–cell and cell–matrix adhesions

(2012) Mithila Burute et al.   CURRENT OPINION IN CELL BIOLOGY

Negative Feedback from Integrins to Cadherins: A Micromechanical Study

(2011) Alia Al-Kilani et al.   BIOPHYSICAL JOURNAL

Focal adhesion kinase: A prominent determinant in breast cancer initiation, progression and metastasis

(2009) Ming Luo et al.   CANCER LETTERS

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage

(2009) P P Provenzano et al.   ONCOGENE

Integrin  1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs

(2009) T. Shibue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular biology of cancer-associated fibroblasts: Can these cells be targeted in anti-cancer therapy?

(2009) Tamas A. Gonda et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Collagen density promotes mammary tumor initiation and progression

(2008) Paolo P Provenzano et al.   BMC Medicine

Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

(2007) Melissa R. Junttila et al.   FASEB JOURNAL