Efficacy of broccoli and glucoraphanin in COVID-19: From hypothesis to proof-of-concept with three experimental clinical cases

Three Novel Prevention, Diagnostic and Treatment Options for COVID-19 Urgently Necessitating Controlled Randomized Trials

(2020) Richard I. Horowitz et al.   MEDICAL HYPOTHESES

Brassica vegetable metabolism by gut microbiota

(2020) Jordan Hindson   Nature Reviews Gastroenterology & Hepatology

Sulforaphane improves syncytiotrophoblast mitochondrial function after in vitro hypoxic and superoxide injury

(2020) A. Langston-Cox et al.   PLACENTA

Is diet partly responsible for differences in COVID-19 death rates between and within countries?

(2020) Jean Bousquet et al.   Clinical and Translational Allergy

Cabbage and fermented vegetables: from death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID‐19

(2020) Jean Bousquet et al.   ALLERGY

Efficacy of a Test-Retest Strategy in Residents and Health Care Personnel of a Nursing Home Facing a COVID-19 Outbreak

(2020) Hubert Blain et al.   Journal of the American Medical Directors Association

The risk of COVID-19 transmission in favelas and slums in Brazil

(2020) R.J. Pereira et al.   PUBLIC HEALTH

Can Activation of NRF2 Be a Strategy against COVID-19?

(2020) Antonio Cuadrado et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma

(2019) J. Bousquet et al.   Clinical and Translational Allergy

Broccoli sprout beverage is safe for thyroid hormonal and autoimmune status: Results of a 12-week randomized trial

(2019) Dionysios V. Chartoumpekis et al.   FOOD AND CHEMICAL TOXICOLOGY

Bioavailability of Sulforaphane Following Ingestion of Glucoraphanin-Rich Broccoli Sprout and Seed Extracts with Active Myrosinase: A Pilot Study of the Effects of Proton Pump Inhibitor Administration

(2019) Jed W. Fahey et al.   Nutrients

Therapeutic and biological activities of berberine: The involvement of Nrf2 signaling pathway

(2019) Milad Ashrafizadeh et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Broccoli or Sulforaphane: Is It the Source or Dose That Matters?

(2019) Yoko Yagishita et al.   MOLECULES

Sulforaphane: Its “Coming of Age” as a Clinically Relevant Nutraceutical in the Prevention and Treatment of Chronic Disease

(2019) Christine A. Houghton   Oxidative Medicine and Cellular Longevity

Types and applications of cough-related questionnaires

(2019) Zhijing Wang et al.   Journal of Thoracic Disease

The antipyretic effect of paracetamol occurs independent of transient receptor potential ankyrin 1–mediated hypothermia and is associated with prostaglandin inhibition in the brain

(2018) Elahe Mirrasekhian et al.   FASEB JOURNAL

Mechanistic link between diesel exhaust particles and respiratory reflexes

(2018) Ryan K. Robinson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3ß/Fyn pathway

(2018) Ying Xin et al.   Redox Biology

Nrf2 expression and function, but not MT expression, is indispensable for sulforaphane-mediated protection against intermittent hypoxia-induced cardiomyopathy in mice

(2018) Shanshan Zhou et al.   Redox Biology

Glucoraphanin: A broccoli sprout extract that ameliorates obesity-induced inflammation and insulin resistance

(2018) Liang Xu et al.   Adipocyte

The orofacial antinociceptive effect of Kaempferol-3-O-rutinoside, isolated from the plant Ouratea fieldingiana, on adult zebrafish (Danio rerio)

(2018) José Eranildo Teles do Nascimento et al.   BIOMEDICINE & PHARMACOTHERAPY

An insight into paracetamol and its metabolites using molecular docking and molecular dynamics simulation

(2018) Yuanqiang Wang et al.   JOURNAL OF MOLECULAR MODELING

A Guide to the Variability of Flavonoids in Brassica oleracea

(2017) Vera Mageney et al.   MOLECULES

Mediterranean diet and inflammaging within the hormesis paradigm

(2017) Morena Martucci et al.   NUTRITION REVIEWS

Cough and airway disease: The role of ion channels

(2017) Sara J. Bonvini et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Antioxidants for Healthy Skin: The Emerging Role of Aryl Hydrocarbon Receptors and Nuclear Factor-Erythroid 2-Related Factor-2

(2017) Masutaka Furue et al.   Nutrients

Sulforaphane for the chemoprevention of bladder cancer: molecular mechanism targeted approach

(2017) Andrew Leone et al.   Oncotarget

Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress

(2017) Eri Kubo et al.   Scientific Reports

Rhizoma Coptidis and Berberine as a Natural Drug to Combat Aging and Aging-Related Diseases via Anti-Oxidation and AMPK Activation

(2017) Zhifang Xu et al.   Aging and Disease

Reactive metabolites of acetaminophen activate and sensitize the capsaicin receptor TRPV1

(2017) Mirjam J. Eberhardt et al.   Scientific Reports

Activation of transient receptor potential ankyrin 1 by quercetin and its analogs

(2016) Toshiyuki Nakamura et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Role of reactive oxygen species and TRP channels in the cough reflex

(2016) Thomas E. Taylor-Clark   CELL CALCIUM

Significance of TRP channels in oxidative stress

(2016) Shinichiro Yamamoto et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Frugal chemoprevention: targeting Nrf2 with foods rich in sulforaphane

(2016) Li Yang et al.   SEMINARS IN ONCOLOGY

Resveratrol and Cardiovascular Diseases

(2016) Dominique Bonnefont-Rousselot   Nutrients

Systemic desensitization through TRPA1 channels by capsazepine and mustard oil - a novel strategy against inflammation and pain

(2016) Katrin Kistner et al.   Scientific Reports

A Randomized Controlled Trial of the Effect of Broccoli Sprouts on Antioxidant Gene Expression and Airway Inflammation in Asthmatics

(2016) Kuladeep Sudini et al.   Journal of Allergy and Clinical Immunology-In Practice

Lack of Effect of Oral Sulforaphane Administration on Nrf2 Expression in COPD: A Randomized, Double-Blind, Placebo Controlled Trial

(2016) Robert A. Wise et al.   PLoS One

Naturally-Occurring Glucosinolates, Glucoraphanin and Glucoerucin, are Antagonists to Aryl Hydrocarbon Receptor as Their Chemopreventive Potency

(2015) Ahmad Faizal Abdull Razis et al.   Asian Pacific Journal of Cancer Prevention

Sulforaphane is anticonvulsant and improves mitochondrial function

(2015) Catalina Carrasco-Pozo et al.   JOURNAL OF NEUROCHEMISTRY

Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation

(2015) Yang Bai et al.   Oxidative Medicine and Cellular Longevity

Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase

(2015) Jed W. Fahey et al.   PLoS One

A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer

(2014) Joshi J. Alumkal et al.   INVESTIGATIONAL NEW DRUGS

Naringenin stimulates cholecystokinin secretion in STC-1 cells

(2014) Min Park et al.   Nutrition Research and Practice

Adamantyl Analogues of Paracetamol as Potent Analgesic Drugs via Inhibition of TRPA1

(2014) Nieves Fresno et al.   PLoS One

Modulation of mitochondrial functions by the indirect antioxidant sulforaphane: A seemingly contradictory dual role and an integrative hypothesis

(2013) Mario Negrette-Guzmán et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles

(2013) David Heber et al.   Food & Function

Mitochondrial respiratory chain complexes: apoptosis sensors mutated in cancer?

(2011) A Lemarie et al.   ONCOGENE

The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system

(2008) Ian M. Copple et al.   HEPATOLOGY

TRPA1 is a major oxidant sensor in murine airway sensory neurons

(2008) Bret F. Bessac et al.   JOURNAL OF CLINICAL INVESTIGATION

Transient Receptor Potential A1 Is a Sensory Receptor for Multiple Products of Oxidative Stress

(2008) D. A. Andersson et al.   JOURNAL OF NEUROSCIENCE