Dimethyl fumarate attenuates 2-VO-induced vascular dementia via activating the Nrf2 signaling pathway in rats

Enhanced cognitive performance in experimental autoimmune encephalomyelitis mice treated with dimethyl fumarate after the appearance of disease symptoms

(2020) Sofia P. das Neves et al.   JOURNAL OF NEUROIMMUNOLOGY

IL-1β induces rod degeneration through the disruption of retinal glutamate homeostasis

(2020) Hugo Charles-Messance et al.   Journal of Neuroinflammation

Anti-inflammatory IL-10 administration rescues depression-associated learning and memory deficits in mice

(2020) Ryan J. Worthen et al.   Journal of Neuroinflammation

Activation of Nrf2/Keap1 pathway by oral Dimethylfumarate administration alleviates oxidative stress and age-associated infertility might be delayed in the mouse ovary

(2019) Nana Akino et al.   Reproductive Biology and Endocrinology

Nigella sativa and thymoquinone attenuate oxidative stress and cognitive impairment following cerebral hypoperfusion in rats

(2019) Sahar Fanoudi et al.   METABOLIC BRAIN DISEASE

Prostaglandin E1 Alleviates Cognitive Dysfunction in Chronic Cerebral Hypoperfusion Rats by Improving Hemodynamics

(2019) Xiaomei Xie et al.   Frontiers in Neuroscience

Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development

(2019) Natalia Robledinos-Antón et al.   Oxidative Medicine and Cellular Longevity

Nrf2 Suppression Delays Diabetic Wound Healing Through Sustained Oxidative Stress and Inflammation

(2019) Min Li et al.   Frontiers in Pharmacology

Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrial alterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol

(2019) Randa Sghaier et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Combined Treatment with Three Natural Antioxidants Enhances Neuroprotection in a SH-SY5Y 3D Culture Model

(2019) Marrazzo et al.   Antioxidants

Neuroprotective effect of Nrf2 activator dimethyl fumarate, on the hippocampal neurons in chemical kindling model in rat

(2018) Neha Singh et al.   EPILEPSY RESEARCH

A review of the mechanisms of action of dimethylfumarate in the treatment of psoriasis

(2018) Jürgen Brück et al.   EXPERIMENTAL DERMATOLOGY

Dimethyl fumarate attenuates reactive microglia and long-term memory deficits following systemic immune challenge

(2018) Hallel C. Paraiso et al.   Journal of Neuroinflammation

Resveratrol loaded solid lipid nanoparticles attenuate mitochondrial oxidative stress in vascular dementia by activating Nrf2/HO-1 pathway

(2018) Aarti Yadav et al.   NEUROCHEMISTRY INTERNATIONAL

DL-3-n-butylphthalide alleviates vascular cognitive impairment induced by chronic cerebral hypoperfusion by activating the Akt/Nrf2 signaling pathway in the hippocampus of rats

(2018) Qianqian Qi et al.   NEUROSCIENCE LETTERS

Dimethyl Fumarate Limits Neuroinflammation and Oxidative Stress and Improves Cognitive Impairment After Polymicrobial Sepsis

(2018) Graciela Freitas Zarbato et al.   NEUROTOXICITY RESEARCH

Astaxanthin Promotes Nrf2/ARE Signaling to Alleviate Renal Fibronectin and Collagen IV Accumulation in Diabetic Rats

(2018) Xiaoyu Zhu et al.   Journal of Diabetes Research

The Protective Effect of Astaxanthin on Cognitive Function via Inhibition of Oxidative Stress and Inflammation in the Brains of Chronic T2DM Rats

(2018) Yonghao Feng et al.   Frontiers in Pharmacology

Heme Oxygenase 1 in the Nervous System: Does It Favor Neuronal Cell Survival or Induce Neurodegeneration?

(2018) Mariapaola Nitti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CZ-7, a new derivative of Claulansine F, ameliorates 2VO-induced vascular dementia in rats through a Nrf2-mediated antioxidant responses

(2018) Dan-dan Liu et al.   ACTA PHARMACOLOGICA SINICA

Chotosan ameliorates cognitive impairment and hippocampus neuronal loss in experimental vascular dementia via activating the Nrf2-mediated antioxidant pathway

(2018) Pan Jiang et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Icariside II Ameliorates Cognitive Impairments Induced by Chronic Cerebral Hypoperfusion by Inhibiting the Amyloidogenic Pathway: Involvement of BDNF/TrkB/CREB Signaling and Up-Regulation of PPARα and PPARγ in Rats

(2018) Caixia Yin et al.   Frontiers in Pharmacology

NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: Molecular mechanisms and possible therapeutic approaches

(2018) Farzane Sivandzade et al.   Redox Biology

Inhibiting inflammation and modulating oxidative stress in oxalate-induced nephrolithiasis with the Nrf2 activator dimethyl fumarate

(2018) Jianning Zhu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Edaravone attenuates oxidative stress induced by chronic cerebral hypoperfusion injury: role of ERK/Nrf2/HO-1 signaling pathway

(2017) Dandan Zhang et al.   NEUROLOGICAL RESEARCH

Hydrogen sulfide ameliorates cognitive dysfunction in streptozotocin-induced diabetic rats: involving suppression in hippocampal endoplasmic reticulum stress

(2017) Wei Zou et al.   Oncotarget

Functions of NQO1 in Cellular Protection and CoQ10 Metabolism and its Potential Role as a Redox Sensitive Molecular Switch

(2017) David Ross et al.   Frontiers in Physiology

Dimethyl fumarate attenuates intracerebroventricular streptozotocin-induced spatial memory impairment and hippocampal neurodegeneration in rats

(2016) Irena Majkutewicz et al.   BEHAVIOURAL BRAIN RESEARCH

Balancing the immune response in the brain: IL-10 and its regulation

(2016) Diogo Lobo-Silva et al.   Journal of Neuroinflammation

Naturally Occurring Nrf2 Activators: Potential in Treatment of Liver Injury

(2016) Ravirajsinh N. Jadeja et al.   Oxidative Medicine and Cellular Longevity

Dimethyl fumarate treatment induces adaptive and innate immune modulation independent of Nrf2

(2016) Ulf Schulze-Topphoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dimethyl Fumarate and Monomethyl Fumarate Promote Post-Ischemic Recovery in Mice

(2016) Yang Yao et al.   Translational Stroke Research

Astroglial NF-kB contributes to white matter damage and cognitive impairment in a mouse model of vascular dementia

(2016) Raman Saggu et al.   Acta Neuropathologica Communications

Deletion of Nrf2 Exacerbates Oxidative Stress After Traumatic Brain Injury in Mice

(2015) Xin-Yu Lu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

DMF, but not other fumarates, inhibits NF-κB activity in vitro in an Nrf2-independent manner

(2015) Geoffrey O. Gillard et al.   JOURNAL OF NEUROIMMUNOLOGY

Dimethylfumarate alleviates early brain injury and secondary cognitive deficits after experimental subarachnoid hemorrhage via activation of Keap1-Nrf2-ARE system

(2015) Yizhi Liu et al.   JOURNAL OF NEUROSURGERY

Lycopene abrogates Aβ(1–42)-mediated neuroinflammatory cascade in an experimental model of Alzheimer’s disease

(2015) Anand Kamal Sachdeva et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Effects of alpha-lipoic acid on spatial learning and memory, oxidative stress, and central cholinergic system in a rat model of vascular dementia

(2015) Ran-ran Zhao et al.   NEUROSCIENCE LETTERS

Dimethyl Fumarate Protects Brain From Damage Produced by Intracerebral Hemorrhage by Mechanism Involving Nrf2

(2015) Xiurong Zhao et al.   STROKE

Effects of donepezil, an acetylcholinesterase inhibitor, on neurogenesis in a rat model of vascular dementia

(2014) Kyoung Ja Kwon et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

AAV serotype 2/1-mediated gene delivery of anti-inflammatory interleukin-10 enhances neurogenesis and cognitive function in APP+PS1 mice

(2011) T Kiyota et al.   GENE THERAPY

Minocycline reduces astrocytic reactivation and neuroinflammation in the hippocampus of a vascular cognitive impairment rat model

(2010) Zhi-You Cai et al.   Neuroscience Bulletin

Cholinergic deficiency involved in vascular dementia: possible mechanism and strategy of treatment

(2009) Juan Wang et al.   ACTA PHARMACOLOGICA SINICA