Anti-inflammatory IL-10 administration rescues depression-associated learning and memory deficits in mice

The antidepressant impact of minocycline in rodents: A systematic review and meta-analysis

(2019) Daniel J. Reis et al.   Scientific Reports

Relationships among stress, emotional intelligence, cognitive intelligence, and cytokines

(2019) Ye-Ha Jung et al.   MEDICINE

Silencing miR-21 induces polarization of astrocytes to the A2 phenotype and improves the formation of synapses by targeting glypican 6 via the signal transducer and activator of transcription-3 pathway after acute ischemic spinal cord injury

(2019) Yanlin Su et al.   FASEB JOURNAL

Stress-Induced Neuronal Colony Stimulating Factor 1 Provokes Microglia-Mediated Neuronal Remodeling and Depressive-like Behavior

(2018) Eric S. Wohleb et al.   BIOLOGICAL PSYCHIATRY

Distinct characteristics of hippocampal pathogenic T H 17 cells in a mouse model of depression

(2018) Eléonore Beurel et al.   BRAIN BEHAVIOR AND IMMUNITY

Defective Inflammatory Pathways in Never-Treated Depressed Patients Are Associated with Poor Treatment Response

(2018) Shariful A. Syed et al.   NEURON

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes

(2018) Timothy R. Hammond et al.   IMMUNITY

Recognition and Treatment of Cognitive Dysfunction in Major Depressive Disorder

(2018) Hannah Zuckerman et al.   Frontiers in Psychiatry

Cognitive control dysfunction in emotion dysregulation and psychopathology of major depression (MD): Evidence from transcranial brain stimulation of the dorsolateral prefrontal cortex (DLPFC)

(2017) Mohammad Ali Salehinejad et al.   JOURNAL OF AFFECTIVE DISORDERS

The Evolutionary Theory of Depression

(2017) Piotr Gałecki et al.   MEDICAL SCIENCE MONITOR

Balancing the immune response in the brain: IL-10 and its regulation

(2016) Diogo Lobo-Silva et al.   Journal of Neuroinflammation

Elimination of microglia improves cognitive function following cranial irradiation

(2016) Munjal M. Acharya et al.   Scientific Reports

Neuron–Microglia Interactions in Mental Health Disorders: “For Better, and For Worse”

(2016) Eric S. Wohleb   Frontiers in Immunology

The current state of the neurogenic theory of depression and anxiety

(2015) Bradley R Miller et al.   CURRENT OPINION IN NEUROBIOLOGY

Impairments in cognition and neural precursor cell proliferation in mice expressing constitutively active glycogen synthase kinase-3

(2015) Marta Pardo et al.   Frontiers in Behavioral Neuroscience

Monocyte trafficking to the brain with stress and inflammation: a novel axis of immune-to-brain communication that influences mood and behavior

(2015) Eric S. Wohleb et al.   Frontiers in Neuroscience

Microglial phagocytosis of live neurons

(2014) Guy C. Brown et al.   NATURE REVIEWS NEUROSCIENCE

Glycogen Synthase Kinase-3 Inhibitors Reverse Deficits in Long-term Potentiation and Cognition in Fragile X Mice

(2013) Aimee V. Franklin et al.   BIOLOGICAL PSYCHIATRY

Learning and memory ... and the immune system

(2013) I. Marin et al.   LEARNING & MEMORY

Dynamic microglial alterations underlie stress-induced depressive-like behavior and suppressed neurogenesis

(2013) T Kreisel et al.   MOLECULAR PSYCHIATRY

Microglia: Multiple roles in surveillance, circuit shaping, and response to injury

(2013) E. E. Benarroch   NEUROLOGY

The JAK/STAT Pathway Is Involved in Synaptic Plasticity

(2012) Céline S. Nicolas et al.   NEURON

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Intracerebral microinjection of interleukin-4/interleukin-13 reduces β-amyloid accumulation in the ipsilateral side and improves cognitive deficits in young amyloid precursor protein 23 mice

(2012) K. Kawahara et al.   NEUROSCIENCE

Depression and Inflammation: An Intricate Relationship

(2011) Robert Dantzer   BIOLOGICAL PSYCHIATRY

AAV serotype 2/1-mediated gene delivery of anti-inflammatory interleukin-10 enhances neurogenesis and cognitive function in APP+PS1 mice

(2011) T Kiyota et al.   GENE THERAPY

Neural mechanisms of the cognitive model of depression

(2011) Seth G. Disner et al.   NATURE REVIEWS NEUROSCIENCE

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Immune modulation of learning, memory, neural plasticity and neurogenesis

(2010) Raz Yirmiya et al.   BRAIN BEHAVIOR AND IMMUNITY

Immune suppression and immune activation in depression

(2010) Joshua Blume et al.   BRAIN BEHAVIOR AND IMMUNITY

Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis

(2010) Amanda Sierra et al.   Cell Stem Cell

CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer’s disease-like pathogenesis in APP+PS1 bigenic mice

(2010) Tomomi Kiyota et al.   FASEB JOURNAL

Cognitive deficits in interleukin-10-deficient mice after peripheral injection of lipopolysaccharide

(2009) Amy F. Richwine et al.   BRAIN BEHAVIOR AND IMMUNITY

Interleukin-10 provides direct trophic support to neurons

(2009) Zhigang Zhou et al.   JOURNAL OF NEUROCHEMISTRY

Resting Microglia Directly Monitor the Functional State of Synapses In Vivo and Determine the Fate of Ischemic Terminals

(2009) H. Wake et al.   JOURNAL OF NEUROSCIENCE

Low serum IL-10 concentrations and loss of regulatory association between IL-6 and IL-10 in adults with major depression

(2009) Firdaus S. Dhabhar et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Adaptive immunity affects learning behavior in mice

(2008) Anna Brynskikh et al.   BRAIN BEHAVIOR AND IMMUNITY

IL-10 modulates depressive-like behavior

(2008) Ana Raquel Mesquita et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Evidence for a cytokine model of cognitive function

(2008) J. McAfoose et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE