Dimethylfumarate alleviates early brain injury and secondary cognitive deficits after experimental subarachnoid hemorrhage via activation of Keap1-Nrf2-ARE system
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Title
Dimethylfumarate alleviates early brain injury and secondary cognitive deficits after experimental subarachnoid hemorrhage via activation of Keap1-Nrf2-ARE system
Authors
Keywords
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Journal
JOURNAL OF NEUROSURGERY
Volume 123, Issue 4, Pages 915-923
Publisher
Journal of Neurosurgery Publishing Group (JNSPG)
Online
2015-01-23
DOI
10.3171/2014.11.jns132348
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- Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway
- (2011) Ralf A. Linker et al. BRAIN
- Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling
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- Fumaric acid and its esters: An emerging treatment for multiple sclerosis with antioxidative mechanism of action
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- Dissociation of Vasospasm and Secondary Effects of Experimental Subarachnoid Hemorrhage by Clazosentan
- (2011) Mohammed Sabri et al. STROKE
- Recombinant human erythropoietin (rhEPO) alleviates early brain injury following subarachnoid hemorrhage in rats: Possible involvement of Nrf2–ARE pathway
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- Dimethylfumarate inhibits microglial and astrocytic inflammation by suppressing the synthesis of nitric oxide, IL-1β, TNF-α and IL-6 in an in-vitro model of brain inflammation
- (2010) Henrik Wilms et al. Journal of Neuroinflammation
- Learning deficits after experimental subarachnoid hemorrhage in rats
- (2010) H. Jeon et al. NEUROSCIENCE
- N-acetylcysteine suppresses oxidative stress in experimental rats with subarachnoid hemorrhage
- (2009) Hua Lu et al. JOURNAL OF CLINICAL NEUROSCIENCE
- Disruption of Nrf2 Enhances Upregulation of Nuclear Factor-κB Activity, Proinflammatory Cytokines, and Intercellular Adhesion Molecule-1 in the Brain after Traumatic Brain Injury
- (2009) Wei Jin et al. MEDIATORS OF INFLAMMATION
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- (2008) Martin Rostami Yazdi et al. CLINICS IN DERMATOLOGY
- Antioxidants and Free Radical Scavengers for the Treatment Of Stroke, Traumatic Brain Injury and Aging
- (2008) J. Weber et al. CURRENT MEDICINAL CHEMISTRY
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