Intranigral Administration of β-Sitosterol-β-D-Glucoside Elicits Neurotoxic A1 Astrocyte Reactivity and Chronic Neuroinflammation in the Rat Substantia Nigra

α-Synucleinopathy associated c-Abl activation causes p53-dependent autophagy impairment

(2020) Md. Razaul Karim et al.   Molecular Neurodegeneration

Inflammation in Traumatic Brain Injury: Roles for Toxic A1 Astrocytes and Microglial–Astrocytic Crosstalk

(2019) David P. Q. Clark et al.   NEUROCHEMICAL RESEARCH

Significant roles of neuroinflammation in Parkinson’s disease: therapeutic targets for PD prevention

(2019) Yujeong Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Selected serum cytokines and nitric oxide as potential multi-marker biosignature panels for Parkinson disease of varying durations: a case-control study

(2019) Dilini Rathnayake et al.   BMC Neurology

Myosin1f-mediated neutrophil migration contributes to acute neuroinflammation and brain injury after stroke in mice

(2019) Yan Wang et al.   Journal of Neuroinflammation

The A1 astrocyte paradigm: New avenues for pharmacological intervention in neurodegeneration

(2019) Jared T. Hinkle et al.   MOVEMENT DISORDERS

Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1−/− mice

(2019) Diana Matheoud et al.   NATURE

Cerebral inducible nitric oxide synthase protein expression in microglia, astrocytes and neurons in Trypanosoma brucei brucei-infected rats

(2019) Raymond Cespuglio et al.   PLoS One

Nigral overexpression of α‐synuclein in a rat Parkinson’s disease model indicates alterations in the enteric nervous system and the gut microbiome

(2019) Sarah M. O’Donovan et al.   NEUROGASTROENTEROLOGY AND MOTILITY

The gut in Parkinson’s disease: Bottom‐up, top‐down, or neither?

(2019) Laurène Leclair‐Visonneau et al.   NEUROGASTROENTEROLOGY AND MOTILITY

The Glymphatic System and Waste Clearance with Brain Aging: A Review

(2018) Helene Benveniste et al.   GERONTOLOGY

Damage to dopaminergic neurons by oxidative stress in Parkinson's disease (Review)

(2018) Ji‑Dong Guo et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Targeted regulation of sympathetic activity in paraventricular nucleus reduces inducible ventricular arrhythmias in rats after myocardial infarction

(2018) Yugen Shi et al.   Journal of Cardiology

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

(2018) Seung Pil Yun et al.   NATURE MEDICINE

Kinetic basis for the activation of human cyclooxygenase-2 rather than cyclooxygenase-1 by nitric oxide

(2018) Jie Qiao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Acute Neuroinflammatory Response in the Substantia Nigra Pars Compacta of Rats after a Local Injection of Lipopolysaccharide

(2018) Yazmin M. Flores-Martinez et al.   Journal of Immunology Research

Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson’s disease

(2018) Gregory P. Williams et al.   Journal of Neuroinflammation

Microglial glutamate release evoked by α-synuclein aggregates is prevented by dopamine

(2018) Mauricio dos-Santos-Pereira et al.   GLIA

Dissecting functional phenotypes of microglia and macrophages in the rat brain after transient cerebral ischemia

(2018) Wenson D. Rajan et al.   GLIA

Evaluation of cerebrospinal fluid proteins as potential biomarkers for early stage Parkinson’s disease diagnosis

(2018) Marcia Cristina T. dos Santos et al.   PLoS One

CD45 is a more sensitive marker than CD3 to diagnose lymphocytic myocarditis in the endomyocardium

(2017) Linde Woudstra et al.   HUMAN PATHOLOGY

Reactive Astrocytes: Production, Function, and Therapeutic Potential

(2017) Shane A. Liddelow et al.   IMMUNITY

Dimethyl Sulfoxide (DMSO) Decreases Cell Proliferation and TNF-α, IFN-γ, and IL-2 Cytokines Production in Cultures of Peripheral Blood Lymphocytes

(2017) Lucas de Abreu Costa et al.   MOLECULES

T cells from patients with Parkinson’s disease recognize α-synuclein peptides

(2017) David Sulzer et al.   NATURE

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

α-Synuclein fibrils recruit peripheral immune cells in the rat brain prior to neurodegeneration

(2017) Ashley S. Harms et al.   Acta Neuropathologica Communications

The BSSG rat model of Parkinson’s disease: progressing towards a valid, predictive model of disease

(2017) Jackalina M. Van Kampen et al.   EPMA Journal

Microglial activation induced by the alarmin S100B is regulated by poly(ADP-ribose) polymerase-1

(2016) Jianguo Xu et al.   GLIA

Identification of a specific α-synuclein peptide (α-Syn 29-40) capable of eliciting microglial superoxide production to damage dopaminergic neurons

(2016) Shijun Wang et al.   Journal of Neuroinflammation

An Interplay of S-Nitrosylation and Metal Ion Binding for Astrocytic S100B Protein

(2016) Małgorzata Bajor et al.   PLoS One

Alpha-Synuclein Proteins Promote Pro-Inflammatory Cascades in Microglia: Stronger Effects of the A53T Mutant

(2016) Claire Hoenen et al.   PLoS One

Striatal Blood–Brain Barrier Permeability in Parkinson'S Disease

(2015) Madison T Gray et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Brain-gut-microbiota axis in Parkinson's disease

(2015) Agata Mulak   WORLD JOURNAL OF GASTROENTEROLOGY

Implications of glial nitric oxide in neurodegenerative diseases

(2015) Jose Enrique Yuste et al.   Frontiers in Cellular Neuroscience

The Progressive BSSG Rat Model of Parkinson's: Recapitulating Multiple Key Features of the Human Disease

(2015) Jackalina M. Van Kampen et al.   PLoS One

Transient transfection of human CDNF gene reduces the 6-hydroxydopamine-induced neuroinflammation in the rat substantia nigra

(2014) Rasajna Nadella et al.   Journal of Neuroinflammation

Dimethyl Sulfoxide Damages Mitochondrial Integrity and Membrane Potential in Cultured Astrocytes

(2014) Chan Yuan et al.   PLoS One

Panax ginseng is neuroprotective in a novel progressive model of Parkinson's disease

(2013) Jackalina M. Van Kampen et al.   EXPERIMENTAL GERONTOLOGY

Glutathione metabolism and Parkinson's disease

(2013) Michelle Smeyne et al.   FREE RADICAL BIOLOGY AND MEDICINE

Safety of the intravenous administration of neurotensin-polyplex nanoparticles in BALB/c mice

(2013) Maria E. Hernandez et al.   Nanomedicine-Nanotechnology Biology and Medicine

Activation of GSK-3β and Caspase-3 Occurs in Nigral Dopamine Neurons during the Development of Apoptosis Activated by a Striatal Injection of 6-Hydroxydopamine

(2013) Daniel Hernandez-Baltazar et al.   PLoS One

S100B is increased in Parkinson’s disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-α pathway

(2012) Kinnari Sathe et al.   BRAIN

An Automated Method to Quantify Microglia Morphology and Application to Monitor Activation State Longitudinally In Vivo

(2012) Cleopatra Kozlowski et al.   PLoS One

Involvement of the mitochondrial apoptotic pathway and nitric oxide synthase in dopaminergic neuronal death induced by 6-hydroxydopamine and lipopolysaccharide

(2012) Sarika Singh et al.   REDOX REPORT

Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson’s Disease

(2011) Hui-Ming Gao et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

S100B Protein Stimulates Microglia Migration via RAGE-dependent Up-regulation of Chemokine Expression and Release

(2011) Roberta Bianchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of Monoclonal Antibodies against Human Leukocyte Common Antigen (CD45)

(2011) Hyang-Mi Shin et al.   Immune Network

Environmental neurotoxin-induced progressive model of parkinsonism in rats

(2010) Wei-Bin Shen et al.   ANNALS OF NEUROLOGY

Comparison Evans Blue injection routes: Intravenous versus intraperitoneal, for measurement of blood–brain barrier in a mice hemorrhage model

(2010) Anatol Manaenko et al.   JOURNAL OF NEUROSCIENCE METHODS

Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway

(2009) Vanja Vukic et al.   NEUROBIOLOGY OF DISEASE

Impact of dopamine–glutamate interactions on striatal neuronal nitric oxide synthase activity

(2009) Kristina E. Hoque et al.   PSYCHOPHARMACOLOGY

Neuroinflammation and Oxidation/Nitration of  -Synuclein Linked to Dopaminergic Neurodegeneration

(2008) H.-M. Gao et al.   JOURNAL OF NEUROSCIENCE