Glial cells in the driver seat of leukodystrophy pathogenesis

Antisense Oligonucleotide Reverses Leukodystrophy in Canavan Disease Mice

(2020) Vanessa Hull et al.   ANNALS OF NEUROLOGY

Astrocytic IGFBP2 and CHI3L1 in cerebrospinal fluid drive cortical metastasis of HER2+breast cancer

(2020) Khairul I. Ansari et al.   CLINICAL & EXPERIMENTAL METASTASIS

Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction

(2020) Nadav I. Weinstock et al.   NEURON

TUBB4A mutations result in both glial and neuronal degeneration in an H-ABC leukodystrophy mouse model

(2020) Sunetra Sase et al.   eLife

The Chitinases as Biomarkers for Amyotrophic Lateral Sclerosis: Signals From the CNS and Beyond

(2020) Nayana Gaur et al.   Frontiers in Neurology

Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease

(2020) Matthew S. Elitt et al.   NATURE

CSF1R Stimulation Promotes Increased Neuroprotection by CD11c+ Microglia in EAE

(2019) Agnieszka Wlodarczyk et al.   Frontiers in Cellular Neuroscience

Efficacy of baricitinib in the treatment of chilblains associated with the type I interferonopathy Aicardi-Goutières syndrome

(2019) Kornvalee Meesilpavikkai et al.   Arthritis & Rheumatology

cGAS activation causes lupus-like autoimmune disorders in a TREX1 mutant mouse model

(2019) Nanyang Xiao et al.   JOURNAL OF AUTOIMMUNITY

Microglia damage precedes major myelin breakdown in X-linked adrenoleukodystrophy and metachromatic leukodystrophy

(2019) Caroline G. Bergner et al.   GLIA

Modeling vanishing white matter disease with patient‐derived induced pluripotent stem cells reveals astrocytic dysfunction

(2019) Ling Zhou et al.   CNS Neuroscience & Therapeutics

Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity

(2019) Jiang Dai et al.   CELL

Opening New Horizons in the Treatment of Childhood Onset Leukodystrophies

(2019) Stina Schiller et al.   NEUROPEDIATRICS

Treatments in Aicardi–Goutières syndrome

(2019) Yanick J Crow et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Diagnosis, prognosis, and treatment of leukodystrophies

(2019) Marjo S van der Knaap et al.   LANCET NEUROLOGY

Megalencephalic Leukoencephalopathy with Subcortical Cysts Protein-1 (MLC1) Counteracts Astrocyte Activation in Response to Inflammatory Signals

(2019) Maria Stefania Brignone et al.   MOLECULAR NEUROBIOLOGY

Myelin in the Central Nervous System: Structure, Function, and Pathology

(2019) Christine Stadelmann et al.   PHYSIOLOGICAL REVIEWS

Phenotypic Expansion in Nasu-Hakola Disease: Immunological Findings in Three Patients and Proposal of a Unifying Pathogenic Hypothesis

(2019) Edoardo Errichiello et al.   Frontiers in Immunology

Vanishing white matter: deregulated integrated stress response as therapy target

(2019) Truus E. M. Abbink et al.   Annals of Clinical and Translational Neurology

Generation of three iPSC lines from fibroblasts of a patient with Aicardi Goutières Syndrome mutated in TREX1

(2019) R.M. Ferraro et al.   Stem Cell Research

Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation

(2019) Hiroko Nobuta et al.   Cell Stem Cell

The role of nucleic acid sensors and type I IFNs in patient populations and animal models of autoinflammation

(2019) Kerstin Nündel et al.   CURRENT OPINION IN IMMUNOLOGY

Refining the concept of GFAP toxicity in Alexander disease

(2019) Albee Messing   Journal of Neurodevelopmental Disorders

Establishment of three iPSC lines from fibroblasts of a patient with Aicardi Goutières syndrome mutated in RNaseH2B

(2019) Rosalba Monica Ferraro et al.   Stem Cell Research

Generation of three isogenic induced Pluripotent Stem Cell lines (iPSCs) from fibroblasts of a patient with Aicardi Goutières Syndrome carrying a c.2471G>A dominant mutation in IFIH1 gene

(2019) Stefania Masneri et al.   Stem Cell Research

Antisense suppression of glial fibrillary acidic protein as a treatment for Alexander disease

(2018) Tracy L. Hagemann et al.   ANNALS OF NEUROLOGY

Dynamism of an Astrocyte In Vivo: Perspectives on Identity and Function

(2018) Kira E. Poskanzer et al.   Annual Review of Physiology

Long-Term Functional Outcomes after Hematopoietic Stem Cell Transplant for Early Infantile Krabbe Disease

(2018) Heather Allewelt et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Astrocytes, an active player in Aicardi-Goutières syndrome

(2018) Sunetra Sase et al.   BRAIN PATHOLOGY

AAVrh10 Gene Therapy Ameliorates Central and Peripheral Nervous System Disease in Canine Globoid Cell Leukodystrophy (Krabbe Disease)

(2018) Allison M. Bradbury et al.   HUMAN GENE THERAPY

Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP): Integrating the literature on hereditary diffuse leukoencephalopathy with spheroids (HDLS) and pigmentary orthochromatic leukodystrophy (POLD)

(2018) Scott J. Adams et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Adulthood leukodystrophies

(2018) Wolfgang Köhler et al.   Nature Reviews Neurology

Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength

(2018) Kevin W. Kelley et al.   NEURON

A Combination of Ontogeny and CNS Environment Establishes Microglial Identity

(2018) F. Chris Bennett et al.   NEURON

Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development

(2018) Ilia D. Vainchtein et al.   SCIENCE

Adult mouse eIF2Bε Arg191His astrocytes display a normal integrated stress response in vitro

(2018) Lisanne E. Wisse et al.   Scientific Reports

Morpholino Antisense Oligomers as a Potential Therapeutic Option for the Correction of Alternative Splicing in PMD, SPG2, and HEMS

(2018) Stephanie Tantzer et al.   Molecular Therapy-Nucleic Acids

Brain microglia activation induced by intracranial administration of oligonucleotides and its pharmacological modulation

(2018) Sebastiano La Maestra et al.   Drug Delivery and Translational Research

RNase H2 Loss in Murine Astrocytes Results in Cellular Defects Reminiscent of Nucleic Acid-Mediated Autoinflammation

(2018) Kareen Bartsch et al.   Frontiers in Immunology

GFAP Mutations in Astrocytes Impair Oligodendrocyte Progenitor Proliferation and Myelination in an hiPSC Model of Alexander Disease

(2018) Li Li et al.   Cell Stem Cell

Motor protein binding and mitochondrial transport are altered by pathogenic TUBB4A variants

(2018) Franca Vulinovic et al.   HUMAN MUTATION

A prospective natural history study of Krabbe disease in a patient cohort with onset between 6 months and 3 years of life

(2018) Nicholas Bascou et al.   Orphanet Journal of Rare Diseases

Colony-Stimulating Factor 1 Receptor (CSF1R) Regulates Microglia Density and Distribution, but Not Microglia Differentiation In Vivo

(2018) Nynke Oosterhof et al.   Cell Reports

Drug Screening Identifies Sigma-1-Receptor as a Target for the Therapy of VWM Leukodystrophy

(2018) Andrea Atzmon et al.   Frontiers in Molecular Neuroscience

Chemical Screening Identifies Enhancers of Mutant Oligodendrocyte Survival and Unmasks a Distinct Pathological Phase in Pelizaeus-Merzbacher Disease

(2018) Matthew S. Elitt et al.   Stem Cell Reports

Globoid cell leukodystrophy (Krabbe disease) in a Merino sheep

(2018) Effie Lee et al.   JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION

CSF1R-related leukoencephalopathy

(2018) Takuya Konno et al.   NEUROLOGY

Reverse-Transcriptase Inhibitors in the Aicardi–Goutières Syndrome

(2018) Gillian I. Rice et al.   NEW ENGLAND JOURNAL OF MEDICINE

Affected astrocytes in the spinal cord of the leukodystrophy vanishing white matter

(2017) Prisca S. Leferink et al.   GLIA

TUBB4A mutations result in specific neuronal and oligodendrocytic defects that closely match clinically distinct phenotypes

(2017) Julian Curiel et al.   HUMAN MOLECULAR GENETICS

Lack of Trex1 Causes Systemic Autoimmunity despite the Presence of Antiretroviral Drugs

(2017) Martin Achleitner et al.   JOURNAL OF IMMUNOLOGY

Mutant eIF2B leads to impaired mitochondrial oxidative phosphorylation in vanishing white matter disease

(2017) Gali Raini et al.   JOURNAL OF NEUROCHEMISTRY

Revised consensus statement on the preventive and symptomatic care of patients with leukodystrophies

(2017) Laura A. Adang et al.   MOLECULAR GENETICS AND METABOLISM

Antisense Oligonucleotide-Based Therapy for Neuromuscular Disease

(2017) Valentina Sardone et al.   MOLECULES

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Antisense Oligonucleotides: Translation from Mouse Models to Human Neurodegenerative Diseases

(2017) Kathleen M. Schoch et al.   NEURON

Bergmann glia translocation: a new disease marker for vanishing white matter identifies therapeutic effects of Guanabenz treatment

(2017) S. Dooves et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

RNA Editing, ADAR1, and the Innate Immune Response

(2017) Qingde Wang et al.   Genes

Megalencephalic leukoencephalopathy with cysts: the Glialcam -null mouse model

(2017) Marianna Bugiani et al.   Annals of Clinical and Translational Neurology

Phospholipase A2 is involved in galactosylsphingosine-induced astrocyte toxicity, neuronal damage and demyelination

(2017) Cedric Misslin et al.   PLoS One

The magnetic resonance imaging spectrum of Pelizaeus–Merzbacher disease: A multicenter study of 19 patients

(2016) Kaoru Sumida et al.   BRAIN & DEVELOPMENT

Endoplasmic reticulum stress and the unfolded protein response in disorders of myelinating glia

(2016) Benjamin L.L. Clayton et al.   BRAIN RESEARCH

Hypomyelinating leukodystrophies - a molecular insight into the white matter pathology

(2016) A. Charzewska et al.   CLINICAL GENETICS

Identification of a conserved and acute neurodegeneration-specific microglial transcriptome in the zebrafish

(2016) Nynke Oosterhof et al.   GLIA

Astrocytes are central in the pathomechanisms of vanishing white matter

(2016) Stephanie Dooves et al.   JOURNAL OF CLINICAL INVESTIGATION

Myelin repair by transplantation of myelin-forming cells in globoid cell leukodystrophy

(2016) Yoichi Kondo et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Treatment for Krabbe's disease: Finding the combination

(2016) Christina R. Mikulka et al.   JOURNAL OF NEUROSCIENCE RESEARCH

A microglial hypothesis of globoid cell leukodystrophy pathology

(2016) Alexandra M. Nicaise et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Functional diversity of astrocytes in neural circuit regulation

(2016) Lucile Ben Haim et al.   NATURE REVIEWS NEUROSCIENCE

Microglia and brain macrophages: An update

(2016) Atsushi Sasaki   NEUROPATHOLOGY

Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling

(2016) W. T. Farmer et al.   SCIENCE

Concise Review: Stem Cell-Based Treatment of Pelizaeus-Merzbacher Disease

(2016) M. Joana Osorio et al.   STEM CELLS

Astrocyte pathology in Alexander disease causes a marked inflammatory environment

(2015) Markel Olabarria et al.   ACTA NEUROPATHOLOGICA

Metachromatic leukodystrophy: Disease spectrum and approaches for treatment

(2015) Diane F. van Rappard et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes

(2015) Ester Cantó et al.   BRAIN

Glial fibrillary acidic protein (GFAP) and the astrocyte intermediate filament system in diseases of the central nervous system

(2015) Elly M Hol et al.   CURRENT OPINION IN CELL BIOLOGY

Enzyme replacement therapy of a novel humanized mouse model of globoid cell leukodystrophy

(2015) Frank Matthes et al.   EXPERIMENTAL NEUROLOGY

History, genetic, and recent advances on Krabbe disease

(2015) Adriana Carol Eleonora Graziano et al.   GENE

Messenger RNA processing is altered in autosomal dominant leukodystrophy

(2015) A. Bartoletti-Stella et al.   HUMAN MOLECULAR GENETICS

Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development

(2015) Kathleen Pestal et al.   IMMUNITY

Galactosylsphingosine (psychosine)-induced demyelination is attenuated by sphingosine 1-phosphate signalling

(2015) C. O'Sullivan et al.   JOURNAL OF CELL SCIENCE

Defects of Lipid Synthesis Are Linked to the Age-Dependent Demyelination Caused by Lamin B1 Overexpression

(2015) H. Rolyan et al.   JOURNAL OF NEUROSCIENCE

Disease specific therapies in leukodystrophies and leukoencephalopathies

(2015) Guy Helman et al.   MOLECULAR GENETICS AND METABOLISM

Case definition and classification of leukodystrophies and leukoencephalopathies

(2015) Adeline Vanderver et al.   MOLECULAR GENETICS AND METABOLISM

Phenotypic characterization of a Csf1r haploinsufficient mouse model of adult-onset leukodystrophy with axonal spheroids and pigmented glia (ALSP)

(2015) Violeta Chitu et al.   NEUROBIOLOGY OF DISEASE

Long-term outcomes after allogeneic hematopoietic stem cell transplantation for metachromatic leukodystrophy: the largest single-institution cohort report

(2015) Alexander A. Boucher et al.   Orphanet Journal of Rare Diseases

Emerging Treatments for Pediatric Leukodystrophies

(2015) Guy Helman et al.   PEDIATRIC CLINICS OF NORTH AMERICA

Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases

(2015) Daxing Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of the Innate Immune Response by Human Neural Precursors Prevails over Oligodendrocyte Progenitor Remyelination to Rescue a Severe Model of Pelizaeus-Merzbacher Disease

(2015) Antoine Marteyn et al.   STEM CELLS

Intracerebral Gene Therapy Using AAVrh.10-hARSA Recombinant Vector to Treat Patients with Early-Onset Forms of Metachromatic Leukodystrophy: Preclinical Feasibility and Safety Assessments in Nonhuman Primates

(2015) Michel Zerah et al.   Human Gene Therapy Clinical Development

Mice with megalencephalic leukoencephalopathy with cysts: A developmental angle

(2014) Mohit Dubey et al.   ANNALS OF NEUROLOGY

X-Linked Adrenoleukodystrophy: Pathogenesis and Treatment

(2014) Marc Engelen et al.   Current Neurology and Neuroscience Reports

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

Adenosine Deaminase Acting on RNA 1 Limits RIG-I RNA Detection and Suppresses IFN Production Responding to Viral and Endogenous RNAs

(2014) Shengyong Yang et al.   JOURNAL OF IMMUNOLOGY

A new mutation in GJC2 associated with subclinical leukodystrophy

(2014) Charles K. Abrams et al.   JOURNAL OF NEUROLOGY

The dual role of astrocyte activation and reactive gliosis

(2014) Milos Pekny et al.   NEUROSCIENCE LETTERS

Umbilical Cord Blood Transplantation to Treat Pelizaeus-Merzbacher Disease in 2 Young Boys

(2014) J. Wishnew et al.   PEDIATRICS

CSF-1 Receptor Signaling in Myeloid Cells

(2014) E. R. Stanley et al.   Cold Spring Harbor Perspectives in Biology

Involvement of ER Stress in Dysmyelination of Pelizaeus-Merzbacher Disease with PLP1 Missense Mutations Shown by iPSC-Derived Oligodendrocytes

(2014) Yuko Numasawa-Kuroiwa et al.   Stem Cell Reports

A De Novo Mutation in the β-Tubulin Gene TUBB4A Results in the Leukoencephalopathy Hypomyelination with Atrophy of the Basal Ganglia and Cerebellum

(2013) Cas Simons et al.   AMERICAN JOURNAL OF HUMAN GENETICS

GFAP Expression as an Indicator of Disease Severity in Mouse Models of Alexander Disease

(2013) Paige L. Jany et al.   ASN Neuro

Hyaluronan accumulation and arrested oligodendrocyte progenitor maturation in vanishing white matter disease

(2013) Marianna Bugiani et al.   BRAIN

Human iPSC-Derived Oligodendrocyte Progenitor Cells Can Myelinate and Rescue a Mouse Model of Congenital Hypomyelination

(2013) Su Wang et al.   Cell Stem Cell

The SAMHD1 knockout mouse model: in vivo veritas?

(2013) Ferdinand Roesch et al.   EMBO JOURNAL

Region- and Age-Dependent Alterations of Glial-Neuronal Metabolic Interactions Correlate with CNS Pathology in a Mouse Model of Globoid Cell Leukodystrophy

(2013) Tore Wergeland Meisingset et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Lamin B1 mediates cell-autonomous neuropathology in a leukodystrophy mouse model

(2013) Mary Y. Heng et al.   JOURNAL OF CLINICAL INVESTIGATION

Aicardi–Goutières syndrome: clues from the RNase H2 knock-out mouse

(2013) Björn Rabe   JOURNAL OF MOLECULAR MEDICINE-JMM

Clinically relevant intronic splicing enhancer mutation in myelin proteolipid protein leads to progressive microglia and astrocyte activation in white and gray matter regions of the brain

(2013) Adam D Bachstetter et al.   Journal of Neuroinflammation

Phenotypic Conversions of "Protoplasmic" to "Reactive" Astrocytes in Alexander Disease

(2013) A. A. Sosunov et al.   JOURNAL OF NEUROSCIENCE

GJC2 promoter mutations causing Pelizaeus–Merzbacher-like disease

(2013) Leo Gotoh et al.   MOLECULAR GENETICS AND METABOLISM

Samhd1 knockout mice: modeling retrovirus restriction in vivo

(2013) Li Wu   Retrovirology

Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy

(2013) A. Biffi et al.   SCIENCE

Oligodendroglia: metabolic supporters of axons

(2013) Brett M. Morrison et al.   TRENDS IN CELL BIOLOGY

A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model

(2013) Isaac M. Chiu et al.   Cell Reports

Astrocytes: Emerging stars in leukodystrophy pathogenesis

(2013) Angela Lanciotti et al.   Translational Neuroscience

Mutations in the autoregulatory domain of β-tubulin 4a cause hereditary dystonia

(2012) Joshua Hersheson et al.   ANNALS OF NEUROLOGY

Aicardi–Goutieres syndrome, a rare neurological disease in children: A new autoimmune disorder?

(2012) Elisa Fazzi et al.   AUTOIMMUNITY REVIEWS

Oct-1 recruitment to the nuclear envelope in adult-onset autosomal dominant leukodystrophy

(2012) Marta Columbaro et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation

(2012) Sayan Nandi et al.   DEVELOPMENTAL BIOLOGY

Correction of Brain Oligodendrocytes by AAVrh.10 Intracerebral Gene Therapy in Metachromatic Leukodystrophy Mice

(2012) Françoise Piguet et al.   HUMAN GENE THERAPY

Zebrafish as a Model for Monocarboxyl Transporter 8-Deficiency

(2012) Gad David Vatine et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bone marrow transplantation increases efficacy of central nervous system-directed enzyme replacement therapy in the murine model of globoid cell leukodystrophy

(2012) Elizabeth Y. Qin et al.   MOLECULAR GENETICS AND METABOLISM

Effect of curcumin in a mouse model of Pelizaeus–Merzbacher disease

(2012) Li-Hua Yu et al.   MOLECULAR GENETICS AND METABOLISM

The effect of bone marrow transplantation on oxidative stress in X-linked adrenoleukodystrophy

(2012) Francieli J. Rockenbach et al.   MOLECULAR GENETICS AND METABOLISM

Therapy of Pelizaeus-Merzbacher disease in mice by feeding a cholesterol-enriched diet

(2012) Gesine Saher et al.   NATURE MEDICINE

GlialCAM, a Protein Defective in a Leukodystrophy, Serves as a ClC-2 Cl− Channel Auxiliary Subunit

(2012) Elena Jeworutzki et al.   NEURON

Human Neural Stem Cells Induce Functional Myelination in Mice with Severe Dysmyelination

(2012) N. Uchida et al.   Science Translational Medicine

Neural Stem Cell Engraftment and Myelination in the Human Brain

(2012) N. Gupta et al.   Science Translational Medicine

Glia: an emerging target for neurological disease therapy

(2012) Akshata A Almad et al.   Stem Cell Research & Therapy

Mutant GlialCAM Causes Megalencephalic Leukoencephalopathy with Subcortical Cysts, Benign Familial Macrocephaly, and Macrocephaly with Retardation and Autism

(2011) Tania López-Hernández et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Gap junctions in inherited human disorders of the central nervous system

(2011) Charles K. Abrams et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Megalencephalic leucoencephalopathy with cysts: defect in chloride currents and cell volume regulation

(2011) Margreet C. Ridder et al.   BRAIN

Childhood leukodystrophies: a clinical perspective

(2011) Alfried Kohlschütter et al.   Expert Review of Neurotherapeutics

Adult-Onset Autosomal Dominant Leukodystrophy: Linking Nuclear Envelope to Myelin

(2011) S.-T. Lin et al.   JOURNAL OF NEUROSCIENCE

Elevated circulating levels of the serum acute-phase protein YKL-40 (chitinase 3-like protein 1) are a marker of obesity and insulin resistance in prepubertal children

(2011) Ioannis Kyrgios et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Knockdown of MLC1 in primary astrocytes causes cell vacuolation: A MLC disease cell model

(2011) Anna Duarri et al.   NEUROBIOLOGY OF DISEASE

GFAP mutations, age at onset, and clinical subtypes in Alexander disease

(2011) M. Prust et al.   NEUROLOGY

Absence of Colony Stimulation Factor-1 Receptor Results in Loss of Microglia, Disrupted Brain Development and Olfactory Deficits

(2011) Bryna Erblich et al.   PLoS One

An autoimmune disease prevented by anti-retroviral drugs

(2011) Gabriele B Beck-Engeser et al.   Retrovirology

Selective Inhibition of a Regulatory Subunit of Protein Phosphatase 1 Restores Proteostasis

(2011) P. Tsaytler et al.   SCIENCE

Pathologic and Phenotypic Alterations in a Mouse Expressing a Connexin47 Missense Mutation That Causes Pelizaeus-Merzbacher–Like Disease in Humans

(2011) Oliver Tress et al.   PLoS Genetics

RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

(2010) C. Frank Bennett et al.   Annual Review of Pharmacology and Toxicology

In vivo CHI3L1 (YKL-40) expression in astrocytes in acute and chronic neurological diseases

(2010) Dafna Bonneh-Barkay et al.   Journal of Neuroinflammation

Defective Glial Maturation in Vanishing White Matter Disease

(2010) Marianna Bugiani et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The burden of inherited leukodystrophies in children

(2010) J. L. Bonkowsky et al.   NEUROLOGY

Oligodendrocytes: biology and pathology

(2009) Monika Bradl et al.   ACTA NEUROPATHOLOGICA

Pelizaeus-Merzbacher-Like disease presentation of MCT8 mutated male subjects

(2009) Catherine Vaurs-Barrière et al.   ANNALS OF NEUROLOGY

Aicardi-Goutières syndrome: description of a late onset case

(2009) Stefano D’Arrigo et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Lamin B1 controls oxidative stress responses via Oct-1

(2009) Ashraf N. Malhas et al.   JOURNAL OF CELL BIOLOGY

Neuronal 3',3,5-Triiodothyronine (T3) Uptake and Behavioral Phenotype of Mice Deficient in Mct8, the Neuronal T3 Transporter Mutated in Allan-Herndon-Dudley Syndrome

(2009) E. K. Wirth et al.   JOURNAL OF NEUROSCIENCE

Myelin under stress

(2009) Maurizio D'Antonio et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy

(2009) N. Cartier et al.   SCIENCE

MR Imaging Characteristics and Neuropathology of the Spinal Cord in Adult-Onset Autosomal Dominant Leukodystrophy with Autonomic Symptoms

(2008) J. Sundblom et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Is microglial apoptosis an early pathogenic change in cerebral X-linked adrenoleukodystrophy?

(2008) Florian S. Eichler et al.   ANNALS OF NEUROLOGY

Hereditary spastic paraplegia is a novel phenotype for GJA12/GJC2 mutations

(2008) Jennifer L. Orthmann-Murphy et al.   BRAIN

Aicardi–Goutières syndrome presenting atypically as a sub-acute leukoencephalopathy

(2008) S. Orcesi et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

The molecular and cellular defects underlying Pelizaeus–Merzbacher disease

(2008) Karen J. Woodward   EXPERT REVIEWS IN MOLECULAR MEDICINE

Astrocytes produce interferon-alpha and CXCL10, but not IL-6 or CXCL8, in aicardi-Goutières syndrome

(2008) Jane T. Van Heteren et al.   GLIA

GlialCAM, an immunoglobulin-like cell adhesion molecule is expressed in glial cells of the central nervous system

(2008) Linda Favre-Kontula et al.   GLIA

Gap Junctions Couple Astrocytes and Oligodendrocytes

(2008) Jennifer L. Orthmann-Murphy et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease

(2008) Ben A. Barres   NEURON

Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells

(2008) Lee E. Finlan et al.   PLoS Genetics