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Title
Reprogramming the genetic code
Authors
Keywords
-
Journal
NATURE REVIEWS GENETICS
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-12-15
DOI
10.1038/s41576-020-00307-7
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- (2020) Daniel L. Dunkelmann et al. Nature Chemistry
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- (2020) Nikolay A. Aleksashin et al. Nature Communications
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- (2020) Claudio Zambaldo et al. BIOORGANIC & MEDICINAL CHEMISTRY
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- (2020) Matthias Tinzl et al. CHEMBIOCHEM
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- (2019) Shuichi Hoshika et al. SCIENCE
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- (2019) Christopher D. Reinkemeier et al. SCIENCE
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- (2019) Maximilian Fottner et al. Nature Chemical Biology
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- (2019) James S Italia et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Plasticity and Constraints of tRNA Aminoacylation Define Directed Evolution of Aminoacyl-tRNA Synthetases
- (2019) Ana Crnković et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Total synthesis of Escherichia coli with a recoded genome
- (2019) Julius Fredens et al. NATURE
- Chemical synthesis rewriting of a bacterial genome to achieve design flexibility and biological functionality
- (2019) Jonathan E. Venetz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Programmed chromosome fission and fusion enable precise large-scale genome rearrangement and assembly
- (2019) Kaihang Wang et al. SCIENCE
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- (2019) Zhenrun J. Zhang et al. Nature Chemical Biology
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- (2019) Erik D. Carlson et al. Nature Communications
- Expanding the limits of the second genetic code with ribozymes
- (2019) Joongoo Lee et al. Nature Communications
- Initiation of Protein Synthesis with Non-Canonical Amino Acids In Vivo
- (2019) Jeffery M. Tharp et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Ribosomal Formation of Thioamide Bonds in Polypeptide Synthesis
- (2019) Rumit Maini et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Playing with the Molecules of Life
- (2018) Douglas D. Young et al. ACS Chemical Biology
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- (2018) Benjamí Oller-Salvia et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Accessibility of the Shine-Dalgarno Sequence Dictates N-Terminal Codon Bias in E. coli
- (2018) Sanchari Bhattacharyya et al. MOLECULAR CELL
- Mutually orthogonal pyrrolysyl-tRNA synthetase/tRNA pairs
- (2018) Julian C. W. Willis et al. Nature Chemistry
- Adaptive evolution of genomically recodedEscherichia coli
- (2018) Timothy M. Wannier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetically Incorporating Two Distinct Post-translational Modifications into One Protein Simultaneously
- (2018) Sumana Venkat et al. ACS Synthetic Biology
- Mutually Orthogonal DNA Replication Systems In Vivo
- (2018) Garri A. Arzumanyan et al. ACS Synthetic Biology
- Expanding the genetic code to study protein-protein interactions
- (2018) Kathrin Lang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Context effects of genetic code expansion by stop codon suppression
- (2018) Yonatan Chemla et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Recent advances in the optical control of protein function through genetic code expansion
- (2018) Taylor Courtney et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Evaluation of 244,000 synthetic sequences reveals design principles to optimize translation in Escherichia coli
- (2018) Guillaume Cambray et al. NATURE BIOTECHNOLOGY
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- (2018) Pragya Mittal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2018) Nicolas Huguenin-Dezot et al. NATURE
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- (2018) Wolfgang H. Schmied et al. NATURE
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- (2018) Jennifer S. Spence et al. Nature Chemical Biology
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- (2018) Elizabeth S. Maywood et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2017) Jason W. Chin NATURE
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- (2017) Yorke Zhang et al. NATURE
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- (2017) Toke P Krogager et al. NATURE BIOTECHNOLOGY
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- (2017) Xiaozhou Luo et al. Nature Chemical Biology
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- (2017) Christian Hoppmann et al. Nature Chemical Biology
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- (2015) Anaëlle Dumas et al. Chemical Science
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- (2015) Takahito Mukai et al. Scientific Reports
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- (2015) Nan Shao et al. Scientific Reports
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- (2014) Moritz Pott et al. ACS Chemical Biology
- Bioorthogonal Reactions for Labeling Proteins
- (2014) Kathrin Lang et al. ACS Chemical Biology
- Expanding and Reprogramming the Genetic Code of Cells and Animals
- (2014) Jason W. Chin Annual Review of Biochemistry
- Comparative genomics highlights the unique biology of Methanomassiliicoccales, a Thermoplasmatales-related seventh order of methanogenic archaea that encodes pyrrolysine
- (2014) Guillaume Borrel et al. BMC GENOMICS
- Cellular Incorporation of Unnatural Amino Acids and Bioorthogonal Labeling of Proteins
- (2014) Kathrin Lang et al. CHEMICAL REVIEWS
- Concerted, Rapid, Quantitative, and Site-Specific Dual Labeling of Proteins
- (2014) Amit Sachdeva et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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- (2014) Wolfgang H. Schmied et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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- (2014) Thomas S Elliott et al. NATURE BIOTECHNOLOGY
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- (2014) Arjun Ravikumar et al. Nature Chemical Biology
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- (2014) Kaihang Wang et al. Nature Chemistry
- Simultaneous non-contiguous deletions using large synthetic DNA and site-specific recombinases
- (2014) Radha Krishnakumar et al. NUCLEIC ACIDS RESEARCH
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- (2014) Tamir Tuller et al. NUCLEIC ACIDS RESEARCH
- Polyspecific pyrrolysyl-tRNA synthetases from directed evolution
- (2014) Li-Tao Guo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Unique Characteristics of the Pyrrolysine System in the 7th Order of Methanogens: Implications for the Evolution of a Genetic Code Expansion Cassette
- (2014) Guillaume Borrel et al. ARCHAEA-AN INTERNATIONAL MICROBIOLOGICAL JOURNAL
- An Expanded Genetic Code in Mammalian Cells with a Functional Quadruplet Codon
- (2013) Wei Niu et al. ACS Chemical Biology
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- (2013) Fahui Li et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A Tryptophanyl-tRNA Synthetase/tRNA Pair for Unnatural Amino Acid Mutagenesis inE. coli
- (2013) Abhishek Chatterjee et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Multiple Site-Selective Insertions of Noncanonical Amino Acids into Sequence-Repetitive Polypeptides
- (2013) I-Lin Wu et al. CHEMBIOCHEM
- Reevaluation of the d-Amino Acid Compatibility with the Elongation Event in Translation
- (2013) Tomoshige Fujino et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Efficient translation initiation dictates codon usage at gene start
- (2013) K. Bentele et al. Molecular Systems Biology
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- (2013) M. J. Lajoie et al. SCIENCE
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- (2013) D. B. Goodman et al. SCIENCE
- Implementation of stable and complex biological systems through recombinase-assisted genome engineering
- (2013) Christine Nicole S. Santos et al. Nature Communications
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- (2012) Carolin A. Aldinger et al. FEBS Journal
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- (2012) Ruisheng Jiang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Site-Specific Incorporation of Functional Components into RNA by an Unnatural Base Pair Transcription System
- (2012) Nobuyuki Morohashi et al. MOLECULES
- The anti-Shine–Dalgarno sequence drives translational pausing and codon choice in bacteria
- (2012) Gene-Wei Li et al. NATURE
- Designer proteins: applications of genetic code expansion in cell biology
- (2012) Lloyd Davis et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Unnatural base pair systems toward the expansion of the genetic alphabet in the central dogma
- (2012) Ichiro HIRAO et al. PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- Evolution of multiple, mutually orthogonal prolyl-tRNA synthetase/tRNA pairs for unnatural amino acid mutagenesis in Escherichia coli
- (2012) A. Chatterjee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- EF-P Is Essential for Rapid Synthesis of Proteins Containing Consecutive Proline Residues
- (2012) L. K. Doerfel et al. SCIENCE
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- (2012) S. Ude et al. SCIENCE
- An Evolved Aminoacyl-tRNA Synthetase with Atypical Polysubstrate Specificity,
- (2011) Douglas D. Young et al. BIOCHEMISTRY
- Synthetase polyspecificity as a tool to modulate protein function
- (2011) Douglas D. Young et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Traceless and Site-Specific Ubiquitination of Recombinant Proteins
- (2011) Satpal Virdee et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Amplification, Mutation, and Sequencing of a Six-Letter Synthetic Genetic System
- (2011) Zunyi Yang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Site-Specific Labeling of DNA and RNA Using an Efficiently Replicated and Transcribed Class of Unnatural Base Pairs
- (2011) Young Jun Seo et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- RF1 knockout allows ribosomal incorporation of unnatural amino acids at multiple sites
- (2011) David B F Johnson et al. Nature Chemical Biology
- Highly specific unnatural base pair systems as a third base pair for PCR amplification
- (2011) Rie Yamashige et al. NUCLEIC ACIDS RESEARCH
- Expanding the Genetic Code of Escherichia coli with Phosphoserine
- (2011) H.-S. Park et al. SCIENCE
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- (2011) Farren J. Isaacs et al. SCIENCE
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- (2010) Chang C. Liu et al. Annual Review of Biochemistry
- Generating Permissive Site-Specific Unnatural Aminoacyl-tRNA Synthetases
- (2010) Shigeki J. Miyake-Stoner et al. BIOCHEMISTRY
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- (2010) Arnaud Gautier et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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- (2010) Heinz Neumann et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome
- (2010) Heinz Neumann et al. NATURE
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- (2010) Satpal Virdee et al. Nature Chemical Biology
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- (2010) T. Mukai et al. NUCLEIC ACIDS RESEARCH
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- (2010) Randall A. Hughes et al. NUCLEIC ACIDS RESEARCH
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- (2010) Fumie Iraha et al. NUCLEIC ACIDS RESEARCH
- Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome
- (2010) D. G. Gibson et al. SCIENCE
- An Enhanced System for Unnatural Amino Acid Mutagenesis in E. coli
- (2009) Travis S. Young et al. JOURNAL OF MOLECULAR BIOLOGY
- Transcription of an Expanded Genetic Alphabet
- (2009) Young Jun Seo et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Optimization of an Unnatural Base Pair toward Natural-Like Replication
- (2009) Young Jun Seo et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Enhancing the utility of unnatural amino acid synthetases by manipulating broad substrate specificity
- (2009) Audrey L. Stokes et al. Molecular BioSystems
- Programming cells by multiplex genome engineering and accelerated evolution
- (2009) Harris H. Wang et al. NATURE
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- (2009) Gong Zhang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Coding-Sequence Determinants of Gene Expression in Escherichia coli
- (2009) G. Kudla et al. SCIENCE
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- (2008) Eric Brustad et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Modulation of the Rate of Peptidyl Transfer on the Ribosome by the Nature of Substrates
- (2008) Ingo Wohlgemuth et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2008) Takatsugu Kobayashi et al. JOURNAL OF MOLECULAR BIOLOGY
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- (2008) Heinz Neumann et al. Nature Chemical Biology
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- (2008) M. Y. Pavlov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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