Plasticity and Constraints of tRNA Aminoacylation Define Directed Evolution of Aminoacyl-tRNA Synthetases
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Plasticity and Constraints of tRNA Aminoacylation Define Directed Evolution of Aminoacyl-tRNA Synthetases
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 9, Pages 2294
Publisher
MDPI AG
Online
2019-05-09
DOI
10.3390/ijms20092294
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- In Cellulo Synthesis of Proteins Containing a Fluorescent Oxazole Amino Acid
- (2019) Shengxi Chen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Engineered Aminoacyl-tRNA Synthetases with Improved Selectivity toward Noncanonical Amino Acids
- (2019) Hui Si Kwok et al. ACS Chemical Biology
- A Facile Method for Producing Selenocysteine-Containing Proteins
- (2018) Takahito Mukai et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Custom selenoprotein production enabled by laboratory evolution of recoded bacterial strains
- (2018) Ross Thyer et al. NATURE BIOTECHNOLOGY
- Ribosomal incorporation of backbone modified amino acids via an editing-deficient aminoacyl-tRNA synthetase
- (2018) Emil S. Iqbal et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Engineering posttranslational proofreading to discriminate nonstandard amino acids
- (2018) Aditya M. Kunjapur et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ribosomal Incorporation of Consecutive β-Amino Acids
- (2018) Takayuki Katoh et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Designing seryl-tRNA synthetase for improved serylation of selenocysteine tRNAs
- (2018) Xian Fu et al. FEBS LETTERS
- Overcoming the membrane barrier: Recruitment of γ-glutamyl transferase for intracellular release of metabolic cargo from peptide vectors
- (2017) Tilmann Kuenzl et al. METABOLIC ENGINEERING
- Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria
- (2017) Xiaozhou Luo et al. Nature Chemical Biology
- Crystal structures reveal an elusive functional domain of pyrrolysyl-tRNA synthetase
- (2017) Tateki Suzuki et al. Nature Chemical Biology
- Continuous directed evolution of aminoacyl-tRNA synthetases
- (2017) David I Bryson et al. Nature Chemical Biology
- Biosynthesis and genetic encoding of phosphothreonine through parallel selection and deep sequencing
- (2017) Michael Shaofei Zhang et al. NATURE METHODS
- Logical engineering of D-arm and T-stem of tRNA that enhances d-amino acid incorporation
- (2017) Takayuki Katoh et al. NUCLEIC ACIDS RESEARCH
- A Versatile Toolbox for the Control of Protein Levels Using Nε-Acetyl-l-lysine Dependent Amber Suppression
- (2017) Wolfram Volkwein et al. ACS Synthetic Biology
- Improved Incorporation of Noncanonical Amino Acids by an Engineered tRNATyr Suppressor
- (2016) Benjamin J. Rauch et al. BIOCHEMISTRY
- Altering the Enantioselectivity of Tyrosyl-tRNA Synthetase by Insertion of a Stereospecific Editing Domain
- (2016) Charles J. Richardson et al. BIOCHEMISTRY
- In Vivo Biosynthesis of a β-Amino Acid-Containing Protein
- (2016) Clarissa Melo Czekster et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Evolving Orthogonal Suppressor tRNAs To Incorporate Modified Amino Acids
- (2016) Andre C. Maranhao et al. ACS Synthetic Biology
- Discovery and Investigation of Natural Editing Function against Artificial Amino Acids in Protein Translation
- (2016) Jan-Stefan Völler et al. ACS Central Science
- Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis Using ᴅ-Amino Acids
- (2016) Sebastian Reichau et al. PLoS One
- Chemical Evolution of a Bacterial Proteome
- (2015) Michael Georg Hoesl et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Liposome-Based in Vitro Evolution of Aminoacyl-tRNA Synthetase for Enhanced Pyrrolysine Derivative Incorporation
- (2015) Atsuko Uyeda et al. CHEMBIOCHEM
- Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids
- (2015) Miriam Amiram et al. NATURE BIOTECHNOLOGY
- Efficient genetic encoding of phosphoserine and its nonhydrolyzable analog
- (2015) Daniel T Rogerson et al. Nature Chemical Biology
- Chimeric human mitochondrial PheRS exhibits editing activity to discriminate nonprotein amino acids
- (2015) Ekaterine Kartvelishvili et al. PROTEIN SCIENCE
- Designing logical codon reassignment – Expanding the chemistry in biology
- (2015) Anaëlle Dumas et al. Chemical Science
- Development of potent in vivo mutagenesis plasmids with broad mutational spectra
- (2015) Ahmed H. Badran et al. Nature Communications
- Economical analysis of saturation mutagenesis experiments
- (2015) Carlos G. Acevedo-Rocha et al. Scientific Reports
- Expanded Cellular Amino Acid Pools Containing Phosphoserine, Phosphothreonine, and Phosphotyrosine
- (2014) Justin B. Steinfeld et al. ACS Chemical Biology
- Exploring the Substrate Range of Wild-Type Aminoacyl-tRNA Synthetases
- (2014) Chenguang Fan et al. CHEMBIOCHEM
- Expanded Genetic Code Technologies for Incorporating Modified Lysine at Multiple Sites
- (2014) Tatsuo Yanagisawa et al. CHEMBIOCHEM
- Evolving tRNASec for Efficient Canonical Incorporation of Selenocysteine
- (2014) Ross Thyer et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Engineering the elongation factor Tu for efficient selenoprotein synthesis
- (2014) Ken-ichi Haruna et al. NUCLEIC ACIDS RESEARCH
- Polyspecific pyrrolysyl-tRNA synthetases from directed evolution
- (2014) Li-Tao Guo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pyrrolysyl-tRNA synthetase variants reveal ancestral aminoacylation function
- (2013) Jae-hyeong Ko et al. FEBS LETTERS
- The N-degradome ofEscherichia coli
- (2013) Matthew A. Humbard et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rewiring Translation for Elongation Factor Tu-Dependent Selenocysteine Incorporation
- (2012) Caroline Aldag et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Recent advances in genetic code engineering in Escherichia coli
- (2012) Michael Georg Hoesl et al. CURRENT OPINION IN BIOTECHNOLOGY
- N-Acetyl lysyl-tRNA synthetases evolved by a CcdB-based selection possessN-acetyl lysine specificity in vitro and in vivo
- (2012) Takuya Umehara et al. FEBS LETTERS
- Synthetase polyspecificity as a tool to modulate protein function
- (2011) Douglas D. Young et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- A system for the continuous directed evolution of biomolecules
- (2011) Kevin M. Esvelt et al. NATURE
- De Novo Enzyme Design Using Rosetta3
- (2011) Florian Richter et al. PLoS One
- Expanding the Genetic Code of Escherichia coli with Phosphoserine
- (2011) H.-S. Park et al. SCIENCE
- Engineering of an Orthogonal Aminoacyl-tRNA Synthetase for Efficient Incorporation of the Non-natural Amino Acid O-Methyl-L-tyrosine using Fluorescence-based Bacterial Cell Sorting
- (2010) Sebastian M. Kuhn et al. JOURNAL OF MOLECULAR BIOLOGY
- High-resolution mapping of protein sequence-function relationships
- (2010) Douglas M Fowler et al. NATURE METHODS
- The many levels of control on bacterial selenoprotein synthesis
- (2009) Satoko Yoshizawa et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Kinetic and Functional Analysis of l-Threonine Kinase, the PduX Enzyme ofSalmonella enterica
- (2009) Chenguang Fan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An Enhanced System for Unnatural Amino Acid Mutagenesis in E. coli
- (2009) Travis S. Young et al. JOURNAL OF MOLECULAR BIOLOGY
- Enhancing the utility of unnatural amino acid synthetases by manipulating broad substrate specificity
- (2009) Audrey L. Stokes et al. Molecular BioSystems
- Pyrrolysyl-tRNA synthetase–tRNAPyl structure reveals the molecular basis of orthogonality
- (2009) Kayo Nozawa et al. NATURE
- Programming cells by multiplex genome engineering and accelerated evolution
- (2009) Harris H. Wang et al. NATURE
- Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli
- (2009) Bryson D Bennett et al. Nature Chemical Biology
- Exploring protein fitness landscapes by directed evolution
- (2009) Philip A. Romero et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Homotetrameric Phosphoseryl-tRNA Synthetase fromMethanosarcina mazeiExhibits Half-of-the-sites Activity
- (2008) Scott I. Hauenstein et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Recognition of Non-α-amino Substrates by Pyrrolysyl-tRNA Synthetase
- (2008) Takatsugu Kobayashi et al. JOURNAL OF MOLECULAR BIOLOGY
- Transplantation of a tyrosine editing domain into a tyrosyl-tRNA synthetase variant enhances its specificity for a tyrosine analog
- (2008) K. Oki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now