New codons for efficient production of unnatural proteins in a semisynthetic organism

Mutually orthogonal nonsense-suppression systems and conjugation chemistries for precise protein labeling at up to three distinct sites

(2019) James S Italia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total synthesis of Escherichia coli with a recoded genome

(2019) Julius Fredens et al.   NATURE

Optimization of Replication, Transcription, and Translation in a Semi-Synthetic Organism

(2019) Aaron W. Feldman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reprograming the Replisome of a Semisynthetic Organism for the Expansion of the Genetic Alphabet

(2018) Michael P. Ledbetter et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Creation of unnatural base pairs for genetic alphabet expansion toward synthetic xenobiology

(2018) Kiyofumi Hamashima et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Progress Toward a Semi-Synthetic Organism with an Unrestricted Expanded Genetic Alphabet

(2018) Vivian T. Dien et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Translation of non-standard codon nucleotides reveals minimal requirements for codon-anticodon interactions

(2018) Thomas Philipp Hoernes et al.   Nature Communications

Dissecting the Contribution of Release Factor Interactions to Amber Stop Codon Reassignment Efficiencies of the Methanocaldococcus jannaschii Orthogonal Pair

(2018) David Schwark et al.   Genes

In Vivo Structure–Activity Relationships and Optimization of an Unnatural Base Pair for Replication in a Semi-Synthetic Organism

(2017) Aaron W. Feldman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A semi-synthetic organism that stores and retrieves increased genetic information

(2017) Yorke Zhang et al.   NATURE

Continuous directed evolution of aminoacyl-tRNA synthetases

(2017) David I Bryson et al.   Nature Chemical Biology

A semisynthetic organism engineered for the stable expansion of the genetic alphabet

(2017) Yorke Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic Biology Parts for the Storage of Increased Genetic Information in Cells

(2017) Sydney E. Morris et al.   ACS Synthetic Biology

Design, synthesis, and testing toward a 57-codon genome

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A semi-synthetic organism with an expanded genetic alphabet

(2014) Denis A. Malyshev et al.   NATURE

Revealing the amino acid composition of proteins within an expanded genetic code

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A Versatile Platform for Single- and Multiple-Unnatural Amino Acid Mutagenesis in Escherichia coli

(2013) Abhishek Chatterjee et al.   BIOCHEMISTRY

Natural-like Replication of an Unnatural Base Pair for the Expansion of the Genetic Alphabet and Biotechnology Applications

(2013) Lingjun Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Insights into DNA Replication without Hydrogen Bonds

(2013) Karin Betz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Upgrading protein synthesis for synthetic biology

(2013) Patrick O'Donoghue et al.   Nature Chemical Biology

Genomically Recoded Organisms Expand Biological Functions

(2013) M. J. Lajoie et al.   SCIENCE

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

(2012) Karin Betz et al.   Nature Chemical Biology

Adding New Chemistries to the Genetic Code

(2010) Chang C. Liu et al.   Annual Review of Biochemistry

Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome

(2010) Heinz Neumann et al.   NATURE

Genetic Encoding and Labeling of Aliphatic Azides and Alkynes in Recombinant Proteinsviaa Pyrrolysyl-tRNA Synthetase/tRNACUAPair and Click Chemistry

(2009) Duy P. Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Optimization of an Unnatural Base Pair toward Natural-Like Replication

(2009) Young Jun Seo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diatom plastids depend on nucleotide import from the cytosol

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Protein therapeutics: a summary and pharmacological classification

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