The emerging role of the BDNF-TrkB signaling pathway in the modulation of pain perception
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The emerging role of the BDNF-TrkB signaling pathway in the modulation of pain perception
Authors
Keywords
Brain derived neurotrophic factor, Microglia, Inflammatory pain, Neuropathic pain, Molecular biomarkers
Journal
JOURNAL OF NEUROIMMUNOLOGY
Volume 349, Issue -, Pages 577406
Publisher
Elsevier BV
Online
2020-09-25
DOI
10.1016/j.jneuroim.2020.577406
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- BDNF as a Promising Therapeutic Agent in Parkinson’s Disease
- (2020) Ewelina Palasz et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- BDNF promotes activation of astrocytes and microglia contributing to neuroinflammation and mechanical allodynia in cyclophosphamide-induced cystitis
- (2020) Honglu Ding et al. Journal of Neuroinflammation
- Brain‐derived neurotrophic factor fused with a collagen‐binding domain inhibits neuroinflammation and promotes neurological recovery of traumatic brain injury mice via TrkB signalling
- (2020) Rui Yin et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Function and Mechanisms of Truncated BDNF Receptor TrkB.T1 in Neuropathic Pain
- (2020) Tuoxin Cao et al. Cells
- Targeting neurotrophic factors: Novel approaches to musculoskeletal pain
- (2020) Anne-Marie Malfait et al. PHARMACOLOGY & THERAPEUTICS
- DNA methylation and BDNF expression account for symptoms and widespread hyperalgesia in patients with Chronic Fatigue Syndrome and Fibromyalgia
- (2020) Andrea Polli et al. Arthritis & Rheumatology
- The Role of BDNF in Peripheral Nerve Regeneration: Activity-Dependent Treatments and Val66Met
- (2019) Claire Emma McGregor et al. Frontiers in Cellular Neuroscience
- Microglial BDNF, PI3K, and p-ERK in the Spinal Cord Are Suppressed by Pulsed Radiofrequency on Dorsal Root Ganglion to Ease SNI-Induced Neuropathic Pain in Rats
- (2019) Xueru Xu et al. Pain Research & Management
- Oligodendrocytes regulate presynaptic properties and neurotransmission through BDNF signaling in the mouse brainstem
- (2019) Miae Jang et al. eLife
- Effects of Neurotrophic Factors in Glial Cells in the Central Nervous System: Expression and Properties in Neurodegeneration and Injury
- (2019) Suvi Pöyhönen et al. Frontiers in Physiology
- Partners in crime: NGF and BDNF in visceral dysfunction
- (2019) Ana Coelho et al. Current Neuropharmacology
- Brain-Derived Neurotrophic Factor: A Key Molecule for Memory in the Healthy and the Pathological Brain
- (2019) Magdalena Miranda et al. Frontiers in Cellular Neuroscience
- Epigenetic regulation of microglial phosphatidylinositol 3‐kinase pathway involved in long‐term potentiation and synaptic plasticity in rats
- (2019) Genevieve Saw et al. GLIA
- Brain-derived neurotrophic factor and schizophrenia
- (2019) Pasquale Di Carlo et al. PSYCHIATRIC GENETICS
- No pain, no gain? The effects of pain-promoting neuropeptides and neurotrophins on fracture healing
- (2019) Seungyup Sun et al. BONE
- Targeted Genotyping Identifies Susceptibility Locus in Brain-derived Neurotrophic Factor Gene for Chronic Postsurgical Pain
- (2018) Yuanyuan Tian et al. ANESTHESIOLOGY
- Painful neurotrophins and their role in visceral pain
- (2018) Ana E. López-Pérez et al. BEHAVIOURAL PHARMACOLOGY
- Role of the Prefrontal Cortex in Pain Processing
- (2018) Wei-Yi Ong et al. MOLECULAR NEUROBIOLOGY
- BDNF Activates mTOR to Upregulate NR2B Expression in the Rostral Anterior Cingulate Cortex Required for Inflammatory Pain-Related Aversion in Rats
- (2018) Yuangui Zhang et al. NEUROCHEMICAL RESEARCH
- The histology, physiology, neurochemistry and circuitry of the substantia gelatinosa Rolandi (lamina II) in mammalian spinal cord
- (2018) Adalberto Merighi PROGRESS IN NEUROBIOLOGY
- Sensory neuronal P2RX4 receptors controls BDNF signaling in inflammatory pain
- (2018) Sarah Lalisse et al. Scientific Reports
- BDNF Polymorphism: A Review of Its Diagnostic and Clinical Relevance in Neurodegenerative Disorders
- (2018) Ting Shen et al. Aging and Disease
- The human microglial HMC3 cell line: where do we stand? A systematic literature review
- (2018) Cinzia Dello Russo et al. Journal of Neuroinflammation
- BDNF rs6265 polymorphism methylation in Multiple Sclerosis: A possible marker of disease progression
- (2018) Viviana Nociti et al. PLoS One
- Actions of Brain-Derived Neurotrophin Factor in the Neurogenesis and Neuronal Function, and Its Involvement in the Pathophysiology of Brain Diseases
- (2018) Tadahiro Numakawa et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- More Insight into BDNF against Neurodegeneration: Anti-Apoptosis, Anti-Oxidation, and Suppression of Autophagy
- (2017) Shang-Der Chen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- When Pain Hurts: Nociceptive Stimulation Induces a State of Maladaptive Plasticity and Impairs Recovery after Spinal Cord Injury
- (2017) James W. Grau et al. JOURNAL OF NEUROTRAUMA
- The Val66Met brain-derived neurotrophic factor gene variant interacts with early pain exposure to predict cortisol dysregulation in 7-year-old children born very preterm: Implications for cognition
- (2017) C.M.Y. Chau et al. NEUROSCIENCE
- Brain-derived neurotrophic factor in the infralimbic cortex alleviates inflammatory pain
- (2017) Lupeng Yue et al. NEUROSCIENCE LETTERS
- Neurobiology of local and intercellular BDNF signaling
- (2017) Manju Sasi et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- BDNF and GDNF expression in discrete populations of nociceptors
- (2016) Chiara Salio et al. ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER
- Cellular and molecular mechanisms regulating neuronal growth by brain-derived neurotrophic factor
- (2016) Andres Gonzalez et al. Cytoskeleton
- The Indispensable Roles of Microglia and Astrocytes during Brain Development
- (2016) Kitty Reemst et al. Frontiers in Human Neuroscience
- The brain-derived neurotrophic factor pathway, life stress, and chronic multi-site musculoskeletal pain
- (2016) Ellen Generaal et al. Molecular Pain
- Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse
- (2016) Ye Zhang et al. NEURON
- Regulation of Neurogenesis by Neurotrophins during Adulthood: Expected and Unexpected Roles
- (2016) Marçal Vilar et al. Frontiers in Neuroscience
- Myosin Va mediates BDNF-induced postendocytic recycling of full-length TrkB and its translocation into dendritic spines
- (2015) W.-H. Sui et al. JOURNAL OF CELL SCIENCE
- Astrocytes Promote Oligodendrogenesis after White Matter Damage via Brain-Derived Neurotrophic Factor
- (2015) N. Miyamoto et al. JOURNAL OF NEUROSCIENCE
- Autocrine Action of BDNF on Dendrite Development of Adult-Born Hippocampal Neurons
- (2015) L. Wang et al. JOURNAL OF NEUROSCIENCE
- Neurotrophins and Neuropathic Pain: Role in Pathobiology
- (2015) Nemat Khan et al. MOLECULES
- BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminals
- (2014) Wenling Chen et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Brain-derived neurotrophic factor as a driving force behind neuroplasticity in neuropathic and central sensitization pain: a new therapeutic target?
- (2014) Jo Nijs et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- BDNF-trkB-KCC2-GABA pathway may be related to chronic stress-induced hyperalgesia at both the spinal and supraspinal level
- (2014) Shuhong Dai et al. MEDICAL HYPOTHESES
- BDNF: No gain without pain?
- (2014) Peter A. Smith NEUROSCIENCE
- The BDNF/TrkB Signaling Pathway Is Involved in Heat Hyperalgesia Mediated by Cdk5 in Rats
- (2014) Hong-Hai Zhang et al. PLoS One
- BDNF signaling and survival of striatal neurons
- (2014) Maryna Baydyuk et al. Frontiers in Cellular Neuroscience
- Unlearning chronic pain: A randomized controlled trial to investigate changes in intrinsic brain connectivity following Cognitive Behavioral Therapy
- (2014) Marina Shpaner et al. NeuroImage-Clinical
- Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
- (2013) Christopher N. Parkhurst et al. CELL
- Association of brain-derived neurotrophic factor (BDNF) haploinsufficiency with lower adaptive behaviour and reduced cognitive functioning in WAGR/11p13 deletion syndrome
- (2013) Joan C. Han et al. CORTEX
- BDNF parabrachio-amygdaloid pathway in morphine-induced analgesia
- (2013) Maysa Sarhan et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- BDNF Regulates Atypical PKC at Spinal Synapses to Initiate and Maintain a Centralized Chronic Pain State
- (2013) Ohannes K Melemedjian et al. Molecular Pain
- P2X4 receptors and neuropathic pain
- (2013) Makoto Tsuda et al. Frontiers in Cellular Neuroscience
- Microglia Control Neuronal Network Excitability via BDNF Signalling
- (2013) Francesco Ferrini et al. NEURAL PLASTICITY
- Brain regions associated with psychological pain: implications for a neural network and its relationship to physical pain
- (2012) Esther L. Meerwijk et al. Brain Imaging and Behavior
- The modifier effect of the BDNF gene in the phenotype of the WAGRO syndrome
- (2012) Raquel Rodríguez-López et al. GENE
- Altered Balance of Proteolytic Isoforms of Pro-Brain-Derived Neurotrophic Factor in Autism
- (2012) Kristine L.P. Garcia et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Variant Brain-Derived Neurotrophic Factor Val66Met Polymorphism Alters Vulnerability to Stress and Response to Antidepressants
- (2012) H. Yu et al. JOURNAL OF NEUROSCIENCE
- Neurotrophin regulation of neural circuit development and function
- (2012) Hyungju Park et al. NATURE REVIEWS NEUROSCIENCE
- Brain-derived neurotrophic factor from microglia: a molecular substrate for neuropathic pain
- (2012) Tuan Trang et al. Neuron Glia Biology
- Activity-dependent BDNF release and TRPC signaling is impaired in hippocampal neurons of Mecp2 mutant mice
- (2012) W. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Involvement of spinal cord BDNF in the generation and maintenance of chronic neuropathic pain in rats
- (2011) Luis Constandil et al. BRAIN RESEARCH BULLETIN
- ξUp-regulation of dorsal root ganglia BDNF and trkB receptor in inflammatory pain: an in vivo and in vitro study
- (2011) Ya-Tin Lin et al. Journal of Neuroinflammation
- JIP3 Mediates TrkB Axonal Anterograde Transport and Enhances BDNF Signaling by Directly Bridging TrkB with Kinesin-1
- (2011) S.-H. Huang et al. JOURNAL OF NEUROSCIENCE
- Microglia: A Promising Target for Treating Neuropathic and Postoperative Pain, and Morphine Tolerance
- (2011) Yeong-Ray Wen et al. JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
- Modification of Mecp2 dosage alters axonal transport through the Huntingtin/Hap1 pathway
- (2011) Jean-Christophe Roux et al. NEUROBIOLOGY OF DISEASE
- Self-amplifying autocrine actions of BDNF in axon development
- (2011) P.-L. Cheng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Long-term changes in the ipsilateral substantia nigra after transient focal cerebral ischaemia in rats
- (2010) Hiroto Uchida et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
- Presynaptic BDNF Promotes Postsynaptic Long-Term Potentiation in the Dorsal Striatum
- (2010) Y. Jia et al. JOURNAL OF NEUROSCIENCE
- Time-dependent contribution of non neuronal cells to BDNF production after ischemic stroke in rats
- (2010) Yannick Béjot et al. NEUROCHEMISTRY INTERNATIONAL
- The Genetic Influence on the Cortical Processing of Experimental Pain and the Moderating Effect of Pain Status
- (2010) Helen Vossen et al. PLoS One
- Anterograde Transport of TrkB in Axons Is Mediated by Direct Interaction with Slp1 and Rab27
- (2009) Nariko Arimura et al. DEVELOPMENTAL CELL
- Mechanism underlying activity-dependent insertion of TrkB into the neuronal surface
- (2009) L. Zhao et al. JOURNAL OF CELL SCIENCE
- Variant BDNF Val66Met Polymorphism Affects Extinction of Conditioned Aversive Memory
- (2009) H. Yu et al. JOURNAL OF NEUROSCIENCE
- The common BDNF polymorphism may be a modifier of disease severity in Rett syndrome
- (2009) B. B. Zeev et al. NEUROLOGY
- White matter activated glial cells produce BDNF in a stroke model of monkeys
- (2009) Yuki Sato et al. NEUROSCIENCE RESEARCH
- Microglial Involvement in Neuroplastic Changes Following Focal Brain Ischemia in Rats
- (2009) Alexandre Madinier et al. PLoS One
- Huntingtin as an essential integrator of intracellular vesicular trafficking
- (2009) Juliane P. Caviston et al. TRENDS IN CELL BIOLOGY
- Up-Regulation of P2X4 Receptors in Spinal Microglia after Peripheral Nerve Injury Mediates BDNF Release and Neuropathic Pain
- (2008) L. Ulmann et al. JOURNAL OF NEUROSCIENCE
- The p.Val66Met polymorphism in the BDNF gene protects against early seizures in Rett syndrome
- (2008) J. Nectoux et al. NEUROLOGY
- TrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive Treatment
- (2008) Yun Li et al. NEURON
- Reduced potassium-chloride co-transporter expression in spinal cord dorsal horn neurons contributes to inflammatory pain hypersensitivity in rats
- (2008) W. Zhang et al. NEUROSCIENCE
- Genetic contributions to pain: a review of findings in humans
- (2008) RB Fillingim et al. ORAL DISEASES
- BDNF as a pain modulator
- (2008) A MERIGHI et al. PROGRESS IN NEUROBIOLOGY
- BDNF A196G and C270T gene polymorphisms and susceptibility to multiple sclerosis in the polish population. Gender differences
- (2007) Dagmara Mirowska-Guzel et al. JOURNAL OF NEUROIMMUNOLOGY
- BDNF: A key regulator for protein synthesis-dependent LTP and long-term memory?
- (2007) Yuan Lu et al. NEUROBIOLOGY OF LEARNING AND MEMORY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now