Cellular and molecular mechanisms regulating neuronal growth by brain-derived neurotrophic factor

Slitrk5 Mediates BDNF-Dependent TrkB Receptor Trafficking and Signaling

(2015) Minseok Song et al.   DEVELOPMENTAL CELL

Nerve growth factor promotes reorganization of the axonal microtubule array at sites of axon collateral branching

(2015) Andrea Ketschek et al.   Developmental Neurobiology

Glutamate Stimulates Local Protein Synthesis in the Axons of Rat Cortical Neurons by Activating α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors and Metabotropic Glutamate Receptors

(2015) Wei-Lun Hsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activity-Dependent Rapid Local RhoA Synthesis Is Required for Hippocampal Synaptic Plasticity

(2015) V. Briz et al.   JOURNAL OF NEUROSCIENCE

Exchange Protein Directly Activated by cAMP (EPAC) Regulates Neuronal Polarization through Rap1B

(2015) P. Munoz-Llancao et al.   JOURNAL OF NEUROSCIENCE

Localized regulation of the axon shaft during the emergence of collateral branches

(2015) Gianluca Gallo   Neural Regeneration Research

SNAREs Controlling Vesicular Release of BDNF and Development of Callosal Axons

(2015) Masafumi Shimojo et al.   Cell Reports

RAB-10-Dependent Membrane Transport Is Required for Dendrite Arborization

(2015) Wei Zou et al.   PLoS Genetics

The MAP1B case: An old MAP that is new again

(2014) David Villarroel-Campos et al.   Developmental Neurobiology

The p75 neurotrophin receptor evades the endolysosomal route in neuronal cells, favouring multivesicular bodies specialised for exosomal release

(2014) C. A. Escudero et al.   JOURNAL OF CELL SCIENCE

Rab-mediated trafficking role in neurite formation

(2014) David Villarroel-Campos et al.   JOURNAL OF NEUROCHEMISTRY

BDNF Promotes Axon Branching of Retinal Ganglion Cells via miRNA-132 and p250GAP

(2014) Katharine J. Marler et al.   JOURNAL OF NEUROSCIENCE

The Neurology of mTOR

(2014) Jonathan O. Lipton et al.   NEURON

CRMP2

(2014) Jacque P.K. Ip et al.   NEUROSCIENTIST

Rab5 Isoforms Orchestrate a “Division of Labor” in the Endocytic Network; Rab5C Modulates Rac-Mediated Cell Motility

(2014) Pin-I Chen et al.   PLoS One

Neuronal Signaling through Endocytosis

(2014) K. E. Cosker et al.   Cold Spring Harbor Perspectives in Biology

proBDNF Negatively Regulates Neuronal Remodeling, Synaptic Transmission, and Synaptic Plasticity in Hippocampus

(2014) Jianmin Yang et al.   Cell Reports

Polarized Expression of p75NTR Specifies Axons during Development and Adult Neurogenesis

(2014) Emanuela Zuccaro et al.   Cell Reports

CaMKIIβ-mediated LIM-kinase activation plays a crucial role in BDNF-induced neuritogenesis

(2013) Akihiko Saito et al.   GENES TO CELLS

Rabex-5 Protein Regulates Dendritic Localization of Small GTPase Rab17 and Neurite Morphogenesis in Hippocampal Neurons

(2013) Yasunori Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BDNF-Dependent Recycling Facilitates TrkB Translocation to Postsynaptic Density during LTP via a Rab11-Dependent Pathway

(2013) S.-H. Huang et al.   JOURNAL OF NEUROSCIENCE

BDNF Regulates Rab11-Mediated Recycling Endosome Dynamics to Induce Dendritic Branching

(2013) O. M. Lazo et al.   JOURNAL OF NEUROSCIENCE

Mutant Huntingtin Alters Retrograde Transport of TrkB Receptors in Striatal Dendrites

(2013) G. Liot et al.   JOURNAL OF NEUROSCIENCE

Long-distance retrograde neurotrophic factor signalling in neurons

(2013) Anthony W. Harrington et al.   NATURE REVIEWS NEUROSCIENCE

Branch management: mechanisms of axon branching in the developing vertebrate CNS

(2013) Katherine Kalil et al.   NATURE REVIEWS NEUROSCIENCE

Christianson Syndrome Protein NHE6 Modulates TrkB Endosomal Signaling Required for Neuronal Circuit Development

(2013) Qing Ouyang et al.   NEURON

Pre- and postsynaptic twists in BDNF secretion and action in synaptic plasticity

(2013) Elke Edelmann et al.   NEUROPHARMACOLOGY

Transcript specificity in BDNF-regulated protein synthesis

(2013) Claudia R. Ruiz et al.   NEUROPHARMACOLOGY

Shaping neurons: Long and short range effects of mature and proBDNF signalling upon neuronal structure

(2013) Katrin Deinhardt et al.   NEUROPHARMACOLOGY

Signalling endosomes in axonal transport: Travel updates on the molecular highway

(2013) Nathalie Schmieg et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Regulation of thalamocortical axon branching by BDNF and synaptic vesicle cycling

(2013) Björn Granseth et al.   Frontiers in Neural Circuits

A role for the tyrosine kinase ACK1 in neurotrophin signaling and neuronal extension and branching

(2013) A La Torre et al.   Cell Death & Disease

Val66Met polymorphism of BDNF alters prodomain structure to induce neuronal growth cone retraction

(2013) Agustin Anastasia et al.   Nature Communications

The role of small GTPases in neuronal morphogenesis and polarity

(2012) Christian Gonzalez-Billault et al.   Cytoskeleton

LIM Kinase 1 (LIMK1) Interacts with Tropomyosin-related Kinase B (TrkB) and Mediates Brain-derived Neurotrophic Factor (BDNF)-induced Axonal Elongation

(2012) Qing Dong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small GTPase Rab17 Regulates Dendritic Morphogenesis and Postsynaptic Development of Hippocampal Neurons

(2012) Yasunori Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of Evenness Interrupted (Evi)-Exosome Release at Synaptic Boutons

(2012) Kate Koles et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Focal adhesion kinase modulates Cdc42 activity downstream of positive and negative axon guidance cues

(2012) Jonathan P. Myers et al.   JOURNAL OF CELL SCIENCE

Dock3 Stimulates Axonal Outgrowth via GSK-3 -Mediated Microtubule Assembly

(2012) K. Namekata et al.   JOURNAL OF NEUROSCIENCE

Distinct Subsets of Syt-IV/BDNF Vesicles Are Sorted to Axons versus Dendrites and Recruited to Synapses by Activity

(2012) C. Dean et al.   JOURNAL OF NEUROSCIENCE

Ankyrin Repeat-Rich Membrane Spanning Protein (Kidins220) Is Required for Neurotrophin and Ephrin Receptor-Dependent Dendrite Development

(2012) Y. Chen et al.   JOURNAL OF NEUROSCIENCE

Phosphorylation of CRMP2 (Collapsin Response Mediator Protein 2) Is Involved in Proper Dendritic Field Organization

(2012) N. Yamashita et al.   JOURNAL OF NEUROSCIENCE

Trk Activation of the ERK1/2 Kinase Pathway Stimulates Intermediate Chain Phosphorylation and Recruits Cytoplasmic Dynein to Signaling Endosomes for Retrograde Axonal Transport

(2012) D. J. Mitchell et al.   JOURNAL OF NEUROSCIENCE

LMTK1/AATYK1 Is a Novel Regulator of Axonal Outgrowth That Acts via Rab11 in a Cdk5-Dependent Manner

(2012) T. Takano et al.   JOURNAL OF NEUROSCIENCE

The dendritic tree and brain disorders

(2012) Vaishali A. Kulkarni et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Cholinergic Abnormalities, Endosomal Alterations and Up-Regulation of Nerve Growth Factor Signaling in Niemann-Pick Type C Disease

(2012) Carolina Cabeza et al.   Molecular Neurodegeneration

microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons

(2012) Federico Dajas-Bailador et al.   NATURE NEUROSCIENCE

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Tau protein is involved in morphological plasticity in hippocampal neurons in response to BDNF

(2012) Qian Chen et al.   NEUROCHEMISTRY INTERNATIONAL

ProBDNF Collapses Neurite Outgrowth of Primary Neurons by Activating RhoA

(2012) Ying Sun et al.   PLoS One

Endocytic trafficking of neurotrophins in neural development

(2012) Maria Ascano et al.   TRENDS IN CELL BIOLOGY

Snapin Recruits Dynein to BDNF-TrkB Signaling Endosomes for Retrograde Axonal Transport and Is Essential for Dendrite Growth of Cortical Neurons

(2012) Bing Zhou et al.   Cell Reports

Serum inducible kinase is a positive regulator of cortical dendrite development and is required for BDNF-promoted dendritic arborization

(2011) Shun-Ling Guo et al.   CELL RESEARCH

Cellular mechanisms underlying the regulation of dendritic development by hepatocyte growth factor

(2011) Charles Finsterwald et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

BDNF-Promoted Increases in Proximal Dendrites Occur via CREB-Dependent Transcriptional Regulation of Cypin

(2011) M. Kwon et al.   JOURNAL OF NEUROSCIENCE

Retrolinkin cooperates with endophilin A1 to mediate BDNF–TrkB early endocytic trafficking and signaling from early endosomes

(2011) Xiuping Fu et al.   MOLECULAR BIOLOGY OF THE CELL

Local, persistent activation of Rho GTPases during plasticity of single dendritic spines

(2011) Hideji Murakoshi et al.   NATURE

Neurotrophin-mediated dendrite-to-nucleus signaling revealed by microfluidic compartmentalization of dendrites

(2011) M. S. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-amplifying autocrine actions of BDNF in axon development

(2011) P.-L. Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization

(2011) J. T. Roland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal Growth Cone Retraction Relies on Proneurotrophin Receptor Signaling Through Rac

(2011) K. Deinhardt et al.   Science Signaling

Changes in dendritic complexity and spine morphology in transgenic mice expressing human wild-type tau

(2010) Dara L. Dickstein et al.   Brain Structure & Function

Characterisation of a new regulator of BDNF signalling, Sprouty3, involved in axonal morphogenesis in vivo

(2010) N. Panagiotaki et al.   DEVELOPMENT

Early life stress followed by subsequent adult chronic stress potentiates anxiety and blunts hippocampal structural remodeling

(2010) Lisa Eiland et al.   HIPPOCAMPUS

Regulation of Dendritic Development by BDNF Requires Activation of CRTC1 by Glutamate

(2010) Charles Finsterwald et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Local and Remote Growth Factor Effects after Primate Spinal Cord Injury

(2010) J. H. Brock et al.   JOURNAL OF NEUROSCIENCE

Global Deprivation of Brain-Derived Neurotrophic Factor in the CNS Reveals an Area-Specific Requirement for Dendritic Growth

(2010) S. Rauskolb et al.   JOURNAL OF NEUROSCIENCE

The Late Endosome is Essential for mTORC1 Signaling

(2010) Rory J. Flinn et al.   MOLECULAR BIOLOGY OF THE CELL

Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in neurons

(2010) Yuanyuan Ji et al.   NATURE NEUROSCIENCE

The MAP kinase phosphatase MKP-1 regulates BDNF-induced axon branching

(2010) Freddy Jeanneteau et al.   NATURE NEUROSCIENCE

Branching out: mechanisms of dendritic arborization

(2010) Yuh-Nung Jan et al.   NATURE REVIEWS NEUROSCIENCE

E3 Ligase Nedd4 Promotes Axon Branching by Downregulating PTEN

(2010) Jovana Drinjakovic et al.   NEURON

Rab GTPases-Dependent Endocytic Pathways Regulate Neuronal Migration and Maturation through N-Cadherin Trafficking

(2010) Takeshi Kawauchi et al.   NEURON

Trk retrograde signaling requires persistent, Pincher-directed endosomes

(2010) P. Philippidou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migration

(2010) G. Assaker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathophysiology of Huntingtonʼs disease: from huntingtin functions to potential treatments

(2009) Emmanuel Roze et al.   CURRENT OPINION IN NEUROLOGY

Ankyrin Repeat-rich Membrane Spanning/Kidins220 protein regulates dendritic branching and spine stabilityin vivo

(2009) Synphen H. Wu et al.   Developmental Neurobiology

Essential Role of Hrs in Endocytic Recycling of Full-length TrkB Receptor but Not Its Isoform TrkB.T1

(2009) Shu-Hong Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kidins220/ARMS Modulates the Activity of Microtubule-regulating Proteins and Controls Neuronal Polarity and Development

(2009) Alonso M. Higuero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab11-FIP3 links the Rab11 GTPase and cytoplasmic dynein to mediate transport to the endosomal-recycling compartment

(2009) C. P. Horgan et al.   JOURNAL OF CELL SCIENCE

Axonal Targeting of Trk Receptors via Transcytosis Regulates Sensitivity to Neurotrophin Responses

(2009) M. Ascano et al.   JOURNAL OF NEUROSCIENCE

Endogenous Truncated TrkB.T1 Receptor Regulates Neuronal Complexity and TrkB Kinase Receptor Function In Vivo

(2009) L. Carim-Todd et al.   JOURNAL OF NEUROSCIENCE

Local translation of dendritic RhoA revealed by an improved synaptoneurosome preparation

(2009) José A. Troca-Marín et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TrkB signalling pathways in LTP and learning

(2009) Liliana Minichiello   NATURE REVIEWS NEUROSCIENCE

High-Resolution Fractionation of Signaling Endosomes Containing Different Receptors

(2009) Gretchen McCaffrey et al.   TRAFFIC

Signaling Mechanisms Linking Neuronal Activity to Gene Expression and Plasticity of the Nervous System

(2008) Steven W. Flavell et al.   Annual Review of Neuroscience

Clathrin-dependent Endocytosis Is Required for TrkB-dependent Akt-mediated Neuronal Protection and Dendritic Growth

(2008) Jing Zheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neurotrophin-Dependent Dendritic Filopodial Motility: A Convergence on PI3K Signaling

(2008) B. W. Luikart et al.   JOURNAL OF NEUROSCIENCE

Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes

(2008) Daisuke Satoh et al.   NATURE CELL BIOLOGY

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE

Nedd4 Controls Animal Growth by Regulating IGF-1 Signaling

(2008) X. R. Cao et al.   Science Signaling

The role of cyclic AMP signaling in promoting axonal regeneration after spinal cord injury

(2007) Sari S. Hannila et al.   EXPERIMENTAL NEUROLOGY