More Insight into BDNF against Neurodegeneration: Anti-Apoptosis, Anti-Oxidation, and Suppression of Autophagy

Roles of p62 in BDNF-dependent autophagy suppression and neuroprotection against mitochondrial dysfunction in rat cortical neurons

(2017) Chia-Lin Wu et al.   JOURNAL OF NEUROCHEMISTRY

Differential caspase activity in the cortex and striatum with chronic infusion of 3-nitropropionic acid

(2015) Kyoung Joo Cho et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oncostatin M-dependent Mcl-1 induction mediated by JAK1/2-STAT1/3 and CREB contributes to bioenergetic improvements and protective effects against mitochondrial dysfunction in cortical neurons

(2015) Shih-Hsin Chang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Role of sestrin2 in the regulation of proinflammatory signaling in macrophages

(2015) Ji Hye Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Roles of Sestrin2 and Ribosomal Protein S6 in Transient Global Ischemia-Induced Hippocampal Neuronal Injury

(2015) Yao-Chung Chuang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nuclear Factor-kappaB-Dependent Sestrin2 Induction Mediates the Antioxidant Effects of BDNF Against Mitochondrial Inhibition in Rat Cortical Neurons

(2015) Chia-Lin Wu et al.   MOLECULAR NEUROBIOLOGY

Oxidative Stress in Neurodegenerative Diseases

(2015) Ewa Niedzielska et al.   MOLECULAR NEUROBIOLOGY

Brain-derived neurotrophic factor: Regulation, effects, and potential clinical relevance

(2015) E. E. Benarroch   NEUROLOGY

Memantine exerts functional recovery by improving BDNF and GDNF expression in 3-nitropropionic acid intoxicated mice

(2015) Vijayan Ranju et al.   NEUROSCIENCE LETTERS

Neuroprotective Properties of Cannabigerol in Huntington’s Disease: Studies in R6/2 Mice and 3-Nitropropionate-lesioned Mice

(2014) Sara Valdeolivas et al.   Neurotherapeutics

Antioxidant Activity of Sestrin 2 Controls Neuropathic Pain After Peripheral Nerve Injury

(2013) Wiebke Kallenborn-Gerhardt et al.   ANTIOXIDANTS & REDOX SIGNALING

mTOR, AMBRA1, and autophagy: An intricate relationship

(2013) Francesca Nazio et al.   CELL CYCLE

Induction of sestrin2 as an endogenous protective mechanism against amyloid beta-peptide neurotoxicity in primary cortical culture

(2013) Yueh-Sheng Chen et al.   EXPERIMENTAL NEUROLOGY

Upregulation of Sestrin-2 Expression via P53 Protects Against 1-Methyl-4-Phenylpyridinium (MPP+) Neurotoxicity

(2013) Zhou Daixing et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases

(2013) Bai Lu et al.   NATURE REVIEWS NEUROSCIENCE

BDNF mediates adaptive brain and body responses to energetic challenges

(2013) Krisztina Marosi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

3-Nitropropionic acid induces autophagy by forming mitochondrial permeability transition pores rather than activatiing the mitochondrial fission pathway

(2012) Maria E Solesio et al.   BRITISH JOURNAL OF PHARMACOLOGY

Autophagy in regulation of Toll-like receptor signaling

(2012) Takeshi Into et al.   CELLULAR SIGNALLING

Nrf2-ARE pathway regulates induction of Sestrin-2 expression

(2012) Bo Yeon Shin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Synaptic Plasticity in Neurodegenerative Diseases Evaluated and Modulated by In Vivo Neurophysiological Techniques

(2012) F. Pilato et al.   MOLECULAR NEUROBIOLOGY

c-Jun-dependent sulfiredoxin induction mediates BDNF protection against mitochondrial inhibition in rat cortical neurons

(2012) Chia-Lin Wu et al.   NEUROBIOLOGY OF DISEASE

Brain-Derived Neurotrophic Factor Ameliorates Brain Stem Cardiovascular Dysregulation during Experimental Temporal Lobe Status Epilepticus

(2012) Ching-Yi Tsai et al.   PLoS One

Neuroprotective mechanisms of brain-derived neurotrophic factor against 3-nitropropionic acid toxicity: therapeutic implications for Huntington's disease

(2010) Chia-Lin Wu et al.   Annals of the New York Academy of Sciences

Stress-Responsive Sestrins Link p53 with Redox Regulation and Mammalian Target of Rapamycin Signaling

(2010) Andrei V. Budanov   ANTIOXIDANTS & REDOX SIGNALING

Calcium Dysregulation and Homeostasis of Neural Calcium in the Molecular Mechanisms of Neurodegenerative Diseases Provide Multiple Targets for Neuroprotection

(2010) Gregor Zündorf et al.   ANTIOXIDANTS & REDOX SIGNALING

Mesenchymal stem cell transplantation and DMEM administration in a 3NP rat model of Huntington's disease: Morphological and behavioral outcomes

(2010) Julien Rossignol et al.   BEHAVIOURAL BRAIN RESEARCH

Transcriptional Upregulation of Brain-Derived Neurotrophic Factor in Rostral Ventrolateral Medulla by Angiotensin II

(2010) Samuel H.H. Chan et al.   CIRCULATION RESEARCH

Physiological significance of selective degradation of p62 by autophagy

(2010) Masaaki Komatsu et al.   FEBS LETTERS

Redox Regulation of Lipopolysaccharide-mediated Sulfiredoxin Induction, Which Depends on Both AP-1 and Nrf2

(2010) Hojin Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective autophagy: ubiquitin-mediated recognition and beyond

(2010) Claudine Kraft et al.   NATURE CELL BIOLOGY

Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF

(2010) Elena Puerta et al.   NEUROBIOLOGY OF DISEASE

Erythropoietin and sonic hedgehog mediate the neuroprotective effects of brain-derived neurotrophic factor against mitochondrial inhibition

(2010) Chia-Lin Wu et al.   NEUROBIOLOGY OF DISEASE

Sonic hedgehog mediates BDNF-induced neuroprotection against mitochondrial inhibitor 3-nitropropionic acid

(2009) Chia-Lin Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Role of sestrin2 in peroxide signaling in macrophages

(2009) Silke Essler et al.   FEBS LETTERS

New Insights in the Biology of BDNF Synthesis and Release: Implications in CNS Function

(2009) M. E. Greenberg et al.   JOURNAL OF NEUROSCIENCE

Down-regulation of Bcl-2 enhances autophagy activation and cell death induced by mitochondrial dysfunction in rat striatum

(2009) Xing-Ding Zhang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

The nuts and bolts of AGC protein kinases

(2009) Laura R. Pearce et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Brain-derived neurotrophic factor in neurodegenerative diseases

(2009) Chiara Zuccato et al.   Nature Reviews Neurology

BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neurons

(2009) Sandra Almeida et al.   NEUROBIOLOGY OF DISEASE

Dysregulation of CREB Activation and Histone Acetylation in 3-Nitropropionic Acid-Treated Cortical Neurons: Prevention by BDNF and NGF

(2009) Sandra Almeida et al.   NEUROTOXICITY RESEARCH

Protective effects of brain-derived neurotrophic factor against neurotoxicity of 3-nitropropionic acid in rat cortical neurons

(2009) Chia-Lin Wu et al.   NEUROTOXICOLOGY

p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling

(2008) Andrei V. Budanov et al.   CELL

Autophagy and pattern recognition receptors in innate immunity

(2008) Monica Delgado et al.   IMMUNOLOGICAL REVIEWS

The CREB/CRE transcriptional pathway: protection against oxidative stress-mediated neuronal cell death

(2008) Boyoung Lee et al.   JOURNAL OF NEUROCHEMISTRY