MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis

MicroRNA-29a Alleviates Bile Duct Ligation Exacerbation of Hepatic Fibrosis in Mice through Epigenetic Control of Methyltransferases

(2017) Ya-Ling Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

SOX17 regulates cholangiocyte differentiation and acts as a tumor suppressor in cholangiocarcinoma

(2017) Maite Merino-Azpitarte et al.   JOURNAL OF HEPATOLOGY

A Proof-of-Concept for Epigenetic Therapy of Tissue Fibrosis: Inhibition of Liver Fibrosis Progression by 3-Deazaneplanocin A

(2017) Müjdat Zeybel et al.   MOLECULAR THERAPY

A morphological method for ammonia detection in liver

(2017) Virginia Gutiérrez-de-Juan et al.   PLoS One

A targeted analysis reveals relevant shifts in the methylation and transcription of genes responsible for bile acid homeostasis and drug metabolism in non-alcoholic fatty liver disease

(2016) Helgi B. Schiöth et al.   BMC GENOMICS

Epigenetics in liver disease: from biology to therapeutics

(2016) Timothy Hardy et al.   GUT

Deregulated neddylation in liver fibrosis

(2016) Imanol Zubiete-Franco et al.   HEPATOLOGY

The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17

(2016) Orith Waisbourd-Zinman et al.   HEPATOLOGY

Hepatic stellate cell transdifferentiation involves genome-wide remodeling of the DNA methylation landscape

(2016) Agata Page et al.   JOURNAL OF HEPATOLOGY

Epigenetics in liver disease

(2014) Derek A. Mann   HEPATOLOGY

TRAIL-producing NK cells contribute to liver injury and related fibrogenesis in the context of GNMT deficiency

(2014) Sara Fernández-Álvarez et al.   LABORATORY INVESTIGATION

Relationship Between Methylome and Transcriptome in Patients With Nonalcoholic Fatty Liver Disease

(2013) Susan K. Murphy et al.   GASTROENTEROLOGY

Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease

(2013) Cynthia A. Moylan et al.   HEPATOLOGY

A DNA methylation signature associated with the epigenetic repression of glycine N-methyltransferase in human hepatocellular carcinoma

(2013) Covadonga Huidobro et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

NAFLD, NASH and liver cancer

(2013) Gregory A. Michelotti et al.   Nature Reviews Gastroenterology & Hepatology

Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

(2013) Ingmar Mederacke et al.   Nature Communications

Hepatoma Cells From Mice Deficient in Glycine N -Methyltransferase Have Increased RAS Signaling and Activation of Liver Kinase B1

(2012) Nuria Martínez–López et al.   GASTROENTEROLOGY

Inhibition of natural killer cells protects the liver against acute injury in the absence of glycine N-methyltransferase

(2012) Laura Gomez-Santos et al.   HEPATOLOGY

Histone methyltransferase ASH1 orchestrates fibrogenic gene transcription during myofibroblast transdifferentiation

(2012) Maria Jesus Perugorria et al.   HEPATOLOGY

DNMT1-mediated PTEN hypermethylation confers hepatic stellate cell activation and liver fibrogenesis in rats

(2012) Er-Bao Bian et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A sensitive mass spectrometry method for simultaneous quantification of DNA methylation and hydroxymethylation levels in biological samples

(2011) Thuc Le et al.   ANALYTICAL BIOCHEMISTRY

Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation

(2011) Nieves Embade et al.   HEPATOLOGY

Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation

(2010) A. Baghdasaryan et al.   GUT

MeCP2 Controls an Epigenetic Pathway That Promotes Myofibroblast Transdifferentiation and Fibrosis

(2009) Jelena Mann et al.   GASTROENTEROLOGY

Apoptotic body engulfment by hepatic stellate cells promotes their survival by the JAK/STAT and Akt/NF-κB-dependent pathways

(2009) Joy X. Jiang et al.   JOURNAL OF HEPATOLOGY

TRAIL mediates liver injury by the innate immune system in the bile duct-ligated mouse

(2008) Alisan Kahraman et al.   HEPATOLOGY

GlycineN-methyltransferase is a favorable prognostic marker for human cholangiocarcinoma

(2008) Yu-Chuen Huang et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Oncogenes and Cancer

(2008) Carlo M. Croce   NEW ENGLAND JOURNAL OF MEDICINE