Searching for Peripheral Biomarkers in Neurodegenerative Diseases: The Tryptophan-Kynurenine Metabolic Pathway
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Searching for Peripheral Biomarkers in Neurodegenerative Diseases: The Tryptophan-Kynurenine Metabolic Pathway
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 24, Pages 9338
Publisher
MDPI AG
Online
2020-12-08
DOI
10.3390/ijms21249338
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Are Kynurenines Accomplices or Principal Villains in Dementia? Maintenance of Kynurenine Metabolism
- (2020) Tanaka et al. MOLECULES
- Monoaminergic and Kynurenergic Characterization of Frontotemporal Dementia and Amyotrophic Lateral Sclerosis in Cerebrospinal Fluid and Serum
- (2020) Jana Janssens et al. NEUROCHEMICAL RESEARCH
- The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration
- (2020) Anne-Laure Mahul-Mellier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Aryl Hydrocarbon Receptor Is Expressed in Thyroid Carcinoma and Appears to Mediate Epithelial-Mesenchymal-Transition
- (2020) Sonia Moretti et al. Cancers
- Expression of Tryptophan 2,3-Dioxygenase in Metastatic Uveal Melanoma
- (2020) Terai et al. Cancers
- NAD+ Metabolism and Regulation: Lessons From Yeast
- (2020) Trevor Croft et al. Biomolecules
- Exploring the Etiological Links behind Neurodegenerative Diseases: Inflammatory Cytokines and Bioactive Kynurenines
- (2020) Masaru Tanaka et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- GM1 Oligosaccharide Crosses the Human Blood–Brain Barrier In Vitro by a Paracellular Route
- (2020) Erika Di Biase et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Antidepressant-like effects of kynurenic acid in a modified forced swim test
- (2020) Masaru Tanaka et al. Pharmacological Reports
- Kynurenic Acid Levels are Increased in the CSF of Alzheimer’s Disease Patients
- (2020) Marta González-Sánchez et al. Biomolecules
- Plasma metabolites associated with biomarker evidence of neurodegeneration in cognitively normal older adults
- (2020) Pratishtha Chatterjee et al. JOURNAL OF NEUROCHEMISTRY
- Tryptophan Metabolites Are Associated With Symptoms and Nigral Pathology in Parkinson's Disease
- (2020) Patrick L. Heilman et al. MOVEMENT DISORDERS
- Urinary kynurenine as a biomarker for Parkinson’s disease
- (2020) Jia-he Bai et al. NEUROLOGICAL SCIENCES
- Therapeutic Update on Huntington’s Disease: Symptomatic Treatments and Emerging Disease-Modifying Therapies
- (2020) Deepa Dash et al. Neurotherapeutics
- The Trace Kynurenine, Cinnabarinic Acid, Displays Potent Antipsychotic-Like Activity in Mice and Its Levels Are Reduced in the Prefrontal Cortex of Individuals Affected by Schizophrenia
- (2020) Martina Ulivieri et al. SCHIZOPHRENIA BULLETIN
- Randomized Double-Blind Controlled Trial on the Effect of Proteins with Different Tryptophan/Large Neutral Amino Acid Ratios on Sleep in Adolescents: The PROTMORPHEUS Study
- (2020) Oussama Saidi et al. Nutrients
- Orphan G Protein Coupled Receptors in Affective Disorders
- (2020) Lyndsay R. Watkins et al. Genes
- Animal-Assisted and Pet-Robot Interventions for Ameliorating Behavioral and Psychological Symptoms of Dementia: A Systematic Review and Meta-Analysis
- (2020) Sangki Park et al. Biomedicines
- The Role of GPR120 Receptor in Essential Fatty Acids Metabolism in Schizophrenia
- (2020) Joanna Rog et al. Biomedicines
- Alpha7 nicotinic‐N‐methyl‐D‐aspartate hypothesis in the treatment of schizophrenia and beyond
- (2020) Maju Mathew Koola HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
- An Increased Burden of Highly Active Retrotransposition Competent L1s Is Associated with Parkinson’s Disease Risk and Progression in the PPMI Cohort
- (2020) Abigail L. Pfaff et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Role of Leptin in Inflammation and Vice Versa
- (2020) Antonio Pérez-Pérez et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Role of the Kynurenine Signaling Pathway in Different Chronic Pain Conditions and Potential Use of Therapeutic Agents
- (2020) Filip Jovanovic et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- MicroRNAs Dysregulation and Mitochondrial Dysfunction in Neurodegenerative Diseases
- (2020) Mariano Catanesi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Advances in D-Amino Acids in Neurological Research
- (2020) James M. Seckler et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Calmodulin Binding Proteins and Alzheimer’s Disease: Biomarkers, Regulatory Enzymes and Receptors That Are Regulated by Calmodulin
- (2020) Danton H. O’Day INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Kynurenic acid is a potential overlapped biomarker between diagnosis and treatment response for depression from metabolome analysis
- (2020) Hisayuki Erabi et al. Scientific Reports
- Amyotrophic Lateral Sclerosis: A Neurodegenerative Motor Neuron Disease With Ocular Involvement
- (2020) Pilar Rojas et al. Frontiers in Neuroscience
- Targeting Myeloid-Derived Suppressor Cells in Cancer Immunotherapy
- (2020) Yufei Wang et al. Cancers
- Amino Acid Metabolism in Rheumatoid Arthritis: Friend or Foe?
- (2020) Eleonora Panfili et al. Biomolecules
- Monitoring the Redox Status in Multiple Sclerosis
- (2020) Masaru Tanaka et al. Biomedicines
- Psilocybin as a New Approach to Treat Depression and Anxiety in the Context of Life-Threatening Diseases—A Systematic Review and Meta-Analysis of Clinical Trials
- (2020) Ana Sofia Vargas et al. Biomedicines
- The Biomedical Uses of Inositols: A Nutraceutical Approach to Metabolic Dysfunction in Aging and Neurodegenerative Diseases
- (2020) Antonio J. López-Gambero et al. Biomedicines
- Differential Expression and miRNA–Gene Interactions in Early and Late Mild Cognitive Impairment
- (2020) Leonardo Miranda Brito et al. Biology-Basel
- Early Depression Independently of Other Neuropsychiatric Conditions, Influences Disability and Mortality after Stroke (Research Study—Part of PROPOLIS Study)
- (2020) Katarzyna Kowalska et al. Biomedicines
- Earliest Mechanisms of Dopaminergic Neurons Sufferance in a Novel Slow Progressing Ex Vivo Model of Parkinson Disease in Rat Organotypic Cultures of Substantia Nigra
- (2019) Matteo Dal Ben et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Distribution of Tryptophan-Dependent Indole-3-Acetic Acid Synthesis Pathways in Bacteria Unraveled by Large-Scale Genomic Analysis
- (2019) Pengfan Zhang et al. MOLECULES
- Functional Motor Symptoms in Parkinson’s Disease and Functional Parkinsonism: A Systematic Review
- (2019) Marine Ambar Akkaoui et al. JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES
- The neuropathological diagnosis of Alzheimer’s disease
- (2019) Michael A. DeTure et al. Molecular Neurodegeneration
- Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-β and tau
- (2019) Kelly R. Jacobs et al. NEUROBIOLOGY OF AGING
- Does kynurenic acid act on nicotinic receptors? An assessment of the evidence
- (2019) Trevor W. Stone JOURNAL OF NEUROCHEMISTRY
- Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer’s disease
- (2019) Pratishtha Chatterjee et al. Journal of Neuroinflammation
- Systemic and central nervous system metabolic alterations in Alzheimer’s disease
- (2019) Vera van der Velpen et al. Alzheimers Research & Therapy
- Metabolic Profiling of Human Plasma and Urine, Targeting Tryptophan, Tyrosine and Branched Chain Amino Acid Pathways
- (2019) Andrea Anesi et al. Metabolites
- Chronic dietary supplementation with kynurenic acid, a neuroactive metabolite of tryptophan, decreased body weight without negative influence on densitometry and mandibular bone biomechanical endurance in young rats
- (2019) Ewa Tomaszewska et al. PLoS One
- Microbiome-Gut-Brain Axis and Toll-Like Receptors in Parkinson’s Disease
- (2018) Valentina Caputi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Alternations of Metabolic Profile and Kynurenine Metabolism in the Plasma of Parkinson’s Disease
- (2018) Kuo-Hsuan Chang et al. MOLECULAR NEUROBIOLOGY
- Relevance of Alternative Routes of Kynurenic Acid Production in the Brain
- (2018) L. A. Ramos-Chávez et al. Oxidative Medicine and Cellular Longevity
- Alterations in serum kynurenine pathway metabolites in individuals with high neocortical amyloid-β load: A pilot study
- (2018) Pratishtha Chatterjee et al. Scientific Reports
- The IDO Inhibitor Coptisine Ameliorates Cognitive Impairment in a Mouse Model of Alzheimer's Disease
- (2018) Dan Yu et al. JOURNAL OF ALZHEIMERS DISEASE
- Kynurenine Pathway Metabolites in Alzheimer’s Disease
- (2017) Lasse Melvaer Giil et al. JOURNAL OF ALZHEIMERS DISEASE
- Genetic epidemiology of amyotrophic lateral sclerosis: a systematic review and meta-analysis
- (2017) Zhang-Yu Zou et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Prevalence of depression and anxiety in Multiple Sclerosis: A systematic review and meta-analysis
- (2017) Rosa E. Boeschoten et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Genetic analysis of the SOD1 and C9ORF72 genes in Hungarian patients with amyotrophic lateral sclerosis
- (2017) Kornélia Tripolszki et al. NEUROBIOLOGY OF AGING
- Cognitive and behavioral disorders in Parkinson’s disease: an update. I: cognitive impairments
- (2017) Costanza Papagno et al. NEUROLOGICAL SCIENCES
- Kynurenine pathway metabolism and the microbiota-gut-brain axis
- (2017) P.J. Kennedy et al. NEUROPHARMACOLOGY
- Kynurenines: Tryptophan’s metabolites in exercise, inflammation, and mental health
- (2017) Igor Cervenka et al. SCIENCE
- Pathology of Neurodegenerative Diseases
- (2017) Brittany N. Dugger et al. Cold Spring Harbor Perspectives in Biology
- Multiple sclerosis: Pathology, diagnosis and treatments
- (2017) Wen-Juan Huang et al. Experimental and Therapeutic Medicine
- Embryonic and Postnatal Expression of Aryl Hydrocarbon Receptor mRNA in Mouse Brain
- (2017) Eiki Kimura et al. Frontiers in Neuroanatomy
- Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression
- (2017) Chai K. Lim et al. Scientific Reports
- High-throughput sequencing revealed a novel SETX mutation in a Hungarian patient with amyotrophic lateral sclerosis
- (2017) Kornélia Tripolszki et al. Brain and Behavior
- Urinary Metabolomics Reveals Alterations of Aromatic Amino Acid Metabolism of Alzheimer's Disease in the Transgenic CRND8 Mice
- (2016) Zhi Tang et al. Current Alzheimer Research
- The Kynurenine Pathway in the Acute and Chronic Phases of Cerebral Ischemia
- (2016) María Isabel Cuartero et al. CURRENT PHARMACEUTICAL DESIGN
- Investigational α-synuclein aggregation inhibitors: hope for Parkinson’s disease
- (2016) Nóra Török et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- The prevalence of neuropsychiatric symptoms in Alzheimer's disease: Systematic review and meta-analysis
- (2016) Qing-Fei Zhao et al. JOURNAL OF AFFECTIVE DISORDERS
- Prevalence of anxiety in Parkinson's disease: A systematic review and meta-analysis
- (2016) Martijn P. G. Broen et al. MOVEMENT DISORDERS
- Huntingtons Disease Mice Infected with Toxoplasma gondii Demonstrate Early Kynurenine Pathway Activation, Altered CD8+ T-Cell Responses, and Premature Mortality
- (2016) David W. Donley et al. PLoS One
- Investigation of vitamin D receptor polymorphisms in amyotrophic lateral sclerosis
- (2015) N. Török et al. ACTA NEUROLOGICA SCANDINAVICA
- The inimitable kynurenic acid: The roles of different ionotropic receptors in the action of kynurenic acid at a spinal level
- (2015) Gabor Tuboly et al. BRAIN RESEARCH BULLETIN
- Autonomic system and amyotrophic lateral sclerosis
- (2015) Ezequiel A. Piccione et al. MUSCLE & NERVE
- The Genetic Link between Parkinson’s Disease and the Kynurenine Pathway Is Still Missing
- (2015) Nóra Török et al. Parkinsons Disease
- Indoleamine 2,3 Dioxygenase (IDO) Expression and Activity in Relapsing- Remitting Multiple Sclerosis
- (2015) Roberta Mancuso et al. PLoS One
- Unlearning: NMDA Receptor-Mediated Metaplasticity in the Anterior Piriform Cortex Following Early Odor Preference Training in Rats
- (2014) B. Mukherjee et al. JOURNAL OF NEUROSCIENCE
- Neurotransmissions of antidepressant-like effects of neuromedin U-23 in mice
- (2013) Masaru Tanaka et al. BEHAVIOURAL BRAIN RESEARCH
- The kynurenine pathway as a therapeutic target in cognitive and neurodegenerative disorders
- (2013) Trevor W Stone et al. BRITISH JOURNAL OF PHARMACOLOGY
- 3-hydroxykynurenine and other Parkinson's disease biomarkers discovered by metabolomic analysis
- (2013) Peter A. LeWitt et al. MOVEMENT DISORDERS
- NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease
- (2013) Pierre Paoletti et al. NATURE REVIEWS NEUROSCIENCE
- Expression of Tryptophan 2,3-Dioxygenase and Production of Kynurenine Pathway Metabolites in Triple Transgenic Mice and Human Alzheimer's Disease Brain
- (2013) Wei Wu et al. PLoS One
- Increased 3-Hydroxykynurenine serum concentrations differentiate Alzheimer’s disease patients from controls
- (2012) Markus J. Schwarz et al. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
- Kynurenines in the CNS: recent advances and new questions
- (2012) László Vécsei et al. NATURE REVIEWS DRUG DISCOVERY
- NMDA receptors and metaplasticity: Mechanisms and possible roles in neuropsychiatric disorders
- (2012) Charles F. Zorumski et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Lack of Modulation of Nicotinic Acetylcholine Alpha-7 Receptor Currents by Kynurenic Acid in Adult Hippocampal Interneurons
- (2012) Peter Dobelis et al. PLoS One
- Neurotransmission of the antidepressant-like effects of the growth hormone-releasing hormone antagonist MZ-4-71
- (2011) M. Tanaka et al. BEHAVIOURAL BRAIN RESEARCH
- Antidepressant-like effects of urocortin 3 fragments
- (2011) M. Tanaka et al. BRAIN RESEARCH BULLETIN
- Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration
- (2011) Daniel Zwilling et al. CELL
- The kynurenine system and immunoregulation
- (2011) Yvette Mándi et al. JOURNAL OF NEURAL TRANSMISSION
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- Kynurenine and its metabolites in Alzheimer's disease patients
- (2010) E Gulaj et al. Advances in Medical Sciences
- Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease
- (2010) David J. Bonda et al. REDOX REPORT
- Blood levels of kynurenines, interleukin-23 and soluble human leucocyte antigen-G at different stages of Huntington’s disease
- (2009) Caroline M. Forrest et al. JOURNAL OF NEUROCHEMISTRY
- Effects of the LHRH antagonist Cetrorelix on the brain function in mice
- (2009) Gyula Telegdy et al. NEUROPEPTIDES
- The Kynurenine Pathway and Inflammation in Amyotrophic Lateral Sclerosis
- (2009) Yiquan Chen et al. NEUROTOXICITY RESEARCH
- The Excitotoxin Quinolinic Acid Induces Tau Phosphorylation in Human Neurons
- (2009) Abdur Rahman et al. PLoS One
- The Janus-face kynurenic acid
- (2008) Éva Rózsa et al. JOURNAL OF NEURAL TRANSMISSION
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started