Metabolic Profiling of Human Plasma and Urine, Targeting Tryptophan, Tyrosine and Branched Chain Amino Acid Pathways

The neuroactive potential of the human gut microbiota in quality of life and depression

(2019) Mireia Valles-Colomer et al.   Nature Microbiology

Psychobiotics in mental health, neurodegenerative and neurodevelopmental disorders

(2019) Li-Hao Cheng et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Quantification of Tryptophan Metabolites and Markers of Gut Health in Serum and Plasma—Application to Clinical and Epidemiology Cohorts

(2019) Luke Whiley et al.   ANALYTICAL CHEMISTRY

Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease

(2018) Allison Agus et al.   Cell Host & Microbe

Branched Chain Amino Acids: Beyond Nutrition Metabolism

(2018) Cunxi Nie et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Associations of branched-chain amino acids with parameters of energy balance and survival in colorectal cancer patients: results from the ColoCare study

(2018) Mahmoud Delphan et al.   Metabolomics

Nutrimetabolomics: An Integrative Action for Metabolomic Analyses in Human Nutritional Studies

(2018) Marynka M. Ulaszewska et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A gut-brain neural circuit for nutrient sensory transduction

(2018) Melanie Maya Kaelberer et al.   SCIENCE

Determination of kynurnine and tryptophan, biomarkers of indoleamine 2,3-dioxygenase by LC–MS/MS in plasma and tumor

(2018) Wenyan Wang et al.   Bioanalysis

A validated surrogate analyte LC–MS/MS assay for quantitation of endogenous kynurenine and tryptophan in human plasma

(2018) Dennis Miller et al.   Bioanalysis

Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases

(2017) Susanna Nikolaus et al.   GASTROENTEROLOGY

The Microbiome-Gut-Brain Axis in Health and Disease

(2017) Timothy G. Dinan et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Tryptophan metabolism along the kynurenine and serotonin pathways reveals substantial differences in colon and rectal cancer

(2017) S. Crotti et al.   Metabolomics

Metabolome analysis reveals the association between the kynurenine pathway and human herpesvirus 6 encephalopathy in immunocompetent children

(2017) Yuka Torii et al.   Metabolomics

A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites

(2017) Dylan Dodd et al.   NATURE

Brain–gut–microbiota axis — mood, metabolism and behaviour

(2017) Timothy G. Dinan et al.   Nature Reviews Gastroenterology & Hepatology

Kynurenine pathway metabolism and the microbiota-gut-brain axis

(2017) P.J. Kennedy et al.   NEUROPHARMACOLOGY

Associations Between Dietary Patterns and Longitudinal Quality of Life Changes in Colorectal Cancer Patients: The ColoCare Study

(2017) Biljana Gigic et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

The interface of depression and obesity

(2017) Nattinee Jantaratnotai et al.   Obesity Research & Clinical Practice

Pre-analytical phase management: a review of the procedures from patient preparation to laboratory analysis

(2017) Gabriel Lima-Oliveira et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Kynurenines: Tryptophan’s metabolites in exercise, inflammation, and mental health

(2017) Igor Cervenka et al.   SCIENCE

Microbiota-related Changes in Bile Acid & Tryptophan Metabolism are Associated with Gastrointestinal Dysfunction in a Mouse Model of Autism

(2017) Anna V. Golubeva et al.   EBioMedicine

Target-based metabolomics for the quantitative measurement of 37 pathway metabolites in rat brain and serum using hydrophilic interaction ultra-high-performance liquid chromatography–tandem mass spectrometry

(2016) Jiahui Chen et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Symptoms and patient factors associated with longer time to diagnosis for colorectal cancer: results from a prospective cohort study

(2016) Fiona M Walter et al.   BRITISH JOURNAL OF CANCER

A Simple HPLC–MS/MS Method for Determination of Tryptophan, Kynurenine and Kynurenic Acid in Human Serum and its Potential for Monitoring Antidepressant Therapy

(2016) Li-Jun Hu et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Targeting tryptophan and tyrosine metabolism by liquid chromatography tandem mass spectrometry

(2016) Josep Marcos et al.   JOURNAL OF CHROMATOGRAPHY A

Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat

(2016) John R. Kelly et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Branched-Chain Amino Acids as New Biomarkers of Major Depression - A Novel Neurobiology of Mood Disorder

(2016) Andreas Baranyi et al.   PLoS One

Psychobiotics and the Manipulation of Bacteria–Gut–Brain Signals

(2016) Amar Sarkar et al.   TRENDS IN NEUROSCIENCES

LC–MS/MS-based quantification of kynurenine metabolites, tryptophan, monoamines and neopterin in plasma, cerebrospinal fluid and brain

(2016) René Fuertig et al.   Bioanalysis

Microbial metabolism of dietary components to bioactive metabolites: opportunities for new therapeutic interventions

(2016) Linda S. Zhang et al.   Genome Medicine

Serotonin, tryptophan metabolism and the brain-gut-microbiome axis

(2015) S.M. O’Mahony et al.   BEHAVIOURAL BRAIN RESEARCH

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

(2015) Jessica M. Yano et al.   CELL

Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome

(2015) Saeed Shoaie et al.   Cell Metabolism

Nutrients, Foods, and Colorectal Cancer Prevention

(2015) Mingyang Song et al.   GASTROENTEROLOGY

The gut microbiota and host health: a new clinical frontier

(2015) Julian R Marchesi et al.   GUT

Mental health outcomes during colorectal cancer survivorship: a review of the literature

(2015) Catherine E. Mosher et al.   PSYCHO-ONCOLOGY

The Effect of Emotional Stress and Depression on the Prevalence of Digestive Diseases

(2015) Sang Pyo Lee et al.   Journal of Neurogastroenterology and Motility

Prevalence of comorbid depression and obesity in general practice: a cross-sectional survey

(2014) Mariko Carey et al.   BRITISH JOURNAL OF GENERAL PRACTICE

Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4

(2014) Madhukumar Venkatesh et al.   IMMUNITY

Psychobiotics: A Novel Class of Psychotropic

(2013) Timothy G. Dinan et al.   BIOLOGICAL PSYCHIATRY

Preanalytical Aspects and Sample Quality Assessment in Metabolomics Studies of Human Blood

(2013) P. Yin et al.   CLINICAL CHEMISTRY

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

Commensal Bacteria-Dependent Indole Production Enhances Epithelial Barrier Function in the Colon

(2013) Yosuke Shimada et al.   PLoS One

A simple LC–MS/MS method for determination of kynurenine and tryptophan concentrations in human plasma from HIV-infected patients

(2013) Yong Huang et al.   Bioanalysis

Die DONALD Kohorte

(2012) A.E. Buyken et al.   Bundesgesundheitsblatt-Gesundheitsforschung-Gesundheitsschutz

Quantitative profiling of polar primary metabolites using hydrophilic interaction ultrahigh performance liquid chromatography–tandem mass spectrometry

(2012) Helen G. Gika et al.   JOURNAL OF CHROMATOGRAPHY A

Quantitative profiling of tryptophan metabolites in serum, urine, and cell culture supernatants by liquid chromatography–tandem mass spectrometry

(2011) Wentao Zhu et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

p-cresylsulfate and indoxyl sulfate level at different stages of chronic kidney disease

(2011) Cheng-Jui Lin et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

UPLC–MS-based Urine Metabolomics Reveals Indole-3-lactic Acid and Phenyllactic Acid as Conserved Biomarkers for Alcohol-induced Liver Disease in thePpara-null Mouse Model

(2011) Soumen K. Manna et al.   JOURNAL OF PROTEOME RESEARCH

Recent and potential developments of biofluid analyses in metabolomics

(2011) Aihua Zhang et al.   Journal of Proteomics

The bacterial signal indole increases epithelial-cell tight-junction resistance and attenuates indicators of inflammation

(2009) T. Bansal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early Life Stress Alters Behavior, Immunity, and Microbiota in Rats: Implications for Irritable Bowel Syndrome and Psychiatric Illnesses

(2008) Siobhain M. O'Mahony et al.   BIOLOGICAL PSYCHIATRY