Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression

Cerebrospinal fluid kynurenines in multiple sclerosis; relation to disease course and neurocognitive symptoms

(2016) Shahin Aeinehband et al.   BRAIN BEHAVIOR AND IMMUNITY

Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses

(2015) Mauricio F. Farez et al.   CELL

Body fluid biomarkers for multiple sclerosis—the long road to clinical application

(2015) Charlotte E. Teunissen et al.   Nature Reviews Neurology

Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease

(2015) Simon P. Jones et al.   PLoS One

Indoleamine 2,3 Dioxygenase (IDO) Expression and Activity in Relapsing- Remitting Multiple Sclerosis

(2015) Roberta Mancuso et al.   PLoS One

Quinolinic acid toxicity on oligodendroglial cells: relevance for multiple sclerosis and therapeutic strategies

(2014) Gayathri Sundaram et al.   Journal of Neuroinflammation

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

(2014) Alban Bessede et al.   NATURE

Serum nicotinamide adenine dinucleotide levels through disease course in multiple sclerosis

(2013) Nady Braidy et al.   BRAIN RESEARCH

Quinolinic acid, the inescapable neurotoxin

(2012) Gilles J. Guillemin   FEBS Journal

Detection and quantitation of forty eight cytokines, chemokines, growth factors and nine acute phase proteins in healthy human plasma, saliva and urine

(2012) Alamgir Khan   Journal of Proteomics

Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission?

(2011) Johann Steiner et al.   Journal of Neuroinflammation

An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

(2010) F. J. Quintana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The challenge of multiple sclerosis: How do we cure a chronic heterogeneous disease?

(2009) Howard L. Weiner   ANNALS OF NEUROLOGY

Immunomodulatory effects of Vitamin D in multiple sclerosis

(2009) J. Correale et al.   BRAIN

Interferon-  and Tumor Necrosis Factor-  Mediate the Upregulation of Indoleamine 2,3-Dioxygenase and the Induction of Depressive-Like Behavior in Mice in Response to Bacillus Calmette-Guerin

(2009) J. C. O'Connor et al.   JOURNAL OF NEUROSCIENCE

CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-α: relationship to CNS immune responses and depression

(2009) C L Raison et al.   MOLECULAR PSYCHIATRY

Quantitative profiling of biomarkers related to B-vitamin status, tryptophan metabolism and inflammation in human plasma by liquid chromatography/tandem mass spectrometry

(2009) Øivind Midttun et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Multiple Sclerosis: An Immune or Neurodegenerative Disorder?

(2008) Bruce D. Trapp et al.   Annual Review of Neuroscience