Article
Chemistry, Applied
Dongling Qiao, Jieyi Lu, Zhining Chen, Xizhong Liu, Mengying Li, Binjia Zhang
Summary: This study revealed the effects of zein incorporation on the characteristics of agar/konjac glucomannan matrix, including the reduction in viscosity, sol-gel transition point, and storage modulus, as well as the enhancement of agar aggregation and zein crystalline structure, leading to improved film performance.
FOOD HYDROCOLLOIDS
(2023)
Article
Chemistry, Applied
Shikai Zhang, Ziyang He, Fangzhou Xu, Yue Cheng, Geoffrey I. N. Waterhouse, Dongxiao Sun-Waterhouse, Peng Wu
Summary: The addition of ZPEO in KGM films can modify their properties, leading to high-performance composite films with enhanced tensile strength, water contact angle, and antibacterial properties, as well as the ability to slowly release essential oils.
FOOD HYDROCOLLOIDS
(2022)
Article
Chemistry, Applied
Meng Wang, Yun-Cheng Li, Fan-Bing Meng, Qiao Wang, Zheng-Wu Wang, Da-Yu Liu
Summary: In this study, honeysuckle leaf extract was added to the CMKH composite film. The addition of honeysuckle leaf extract slightly decreased the water vapor barrier properties of the film, but completely blocked UV transmission. The film with honeysuckle leaf extract showed higher elongation at break and exhibited strong antioxidant and antimicrobial activities.
Article
Chemistry, Applied
Rui Lai, Yawei Liu, Jie Liu
Summary: The study found that adding zein or conducting freeze-thaw treatment can improve the storage modulus of KGM composite gels, but excessive zein content may cause partial phase separation. By determining the target characteristics ratio of the final product, composite gels can be better prepared.
FOOD HYDROCOLLOIDS
(2021)
Article
Agriculture, Multidisciplinary
Kexin Meng, Haiyan Gao, Jie Zeng, Jingxiang Zhao, Yueqi Qin, Guanglei Li, Tongchao Su
Summary: The study found that a certain amount of KGM could enhance the thermal stability and anti-aging ability of wheat flour, improve the viscoelastic behavior, and decrease the hardness and gumminess of dough. Mixing flour and dough with KGM addition of 10 or 15 g kg(-1) flour resulted in good quality products.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Food Science & Technology
Kao Wu, Xin Li, Xu Yan, Yi Wan, Likun Miao, Man Xiao, Fatang Jiang, Sheng Chen
Summary: The addition of curdlan to KGM/EC films can significantly improve moisture barrier properties and mechanical properties, with the optimal addition amount being 20% of the total weight. Curdlan mainly acts as a filling component in the films, and too low or too high addition amounts can lead to decreased performance.
Article
Agriculture, Multidisciplinary
Yiyuan Zou, Chao Yuan, Bo Cui, Haojie Sha, Pengfei Liu, Lu Lu, Zhengzong Wu
Summary: The study showed that the inclusion of beta-CD in HCS/KGM composite films led to tighter structure, increased thickness and transparency, improved mechanical properties, reduced moisture content, and significantly enhanced water vapor permeability. The enhanced association between biopolymers in the presence of beta-CD will advance the development of a degradable active composite packaging film.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Nutrition & Dietetics
Teng Song, Hui Liu, Abdul Razak Monto, Tong Shi, Li Yuan, Ruichang Gao
Summary: In this study, zein colloidal particles were fabricated using L-lysine and konjac glucomannan to enhance the storage stability of Pickering emulsions. The addition of L-lysine and konjac glucomannan resulted in smaller particle size and improved stability of the emulsions.
FRONTIERS IN NUTRITION
(2022)
Article
Chemistry, Applied
Rui Lai, Jie Liu, Yawei Liu
Summary: This study investigated the influence of pH and incubation temperature on the morphology and properties of konjac glucomannan (KGM)-zein composites. The results showed that pH and incubation temperature affected the solution concentration, gel formation ability, microstructure, mechanical properties, and crystallinity of the composites.
FOOD HYDROCOLLOIDS
(2023)
Article
Food Science & Technology
Yaqiong Pei, Yanqiu Zhang, Hui Ding, Bin Li, Jun Yang
Summary: The aim of this study was to investigate the physical stability and rheological properties of an oil-in-water emulsion stabilized by a mixture of konjac glucomannan (KGM) and whey protein (WP). Results showed that increasing the concentrations of KGM and WP led to a decrease in droplet size and the formation of a gel-like structure with inverted and resistive flow and stackability. The emulsions exhibited shear thinning behavior and viscoelasticity, with the storage modulus greater than the loss modulus. The findings suggested that the KGM-WP mixture could be used as a substitute for egg yolk in cholesterol-free mayonnaise-like emulsions.
Article
Chemistry, Applied
Wanli Zhang, Jong-Whan Rhim
Summary: Konjac glucomannan (KGM), a safe and edible polysaccharide substance, can be converted into active food packaging films. However, the pure KGM-based film lacks mechanical properties and gas barrier properties due to its strong hydrophilicity, so strategies are needed to improve its performance.
FOOD HYDROCOLLOIDS
(2022)
Article
Chemistry, Applied
Peng Lu, Jinying Guo, Jiawei Fan, Ping Wang, Xiang Yan
Summary: The effects of dual sequential modification using konjac glucomannan and ultrasound treatments on the hydration, rheology and structural characteristics of frozen dough were investigated. The results showed that these treatments improved the textural properties of frozen dough but had a negative impact on its viscoelasticity. Furthermore, they increased the content of free sulfhydryl group and disulfide bond, as well as improved the freeze tolerance of dough. The network structure of treated dough was more ordered and integral compared to the control.
Article
Polymer Science
Jiahui Xiao, Yueyang Ji, Zixin Gao, Yunfeng Dai, Xiufang Li, Yanfei Feng, Renchuan You
Summary: This study developed natural silk fibroin nanofibers (SNF) scaffolds with extracellular matrix-mimicking architecture and tunable properties by using the natural polysaccharide konjac glucomannan (KGM) as a physical adhesive. The introduction of a small amount of KGM can confer the SNF scaffolds good structural stability in an aqueous environment, but does not significantly sacrifice the nanofibrous morphology and porosity of the scaffolds.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Wei Liang, Jiayu Zheng, Ahmed S. M. Saleh, Wenqing Zhao, Xinyue Liu, Chunyan Su, Mengting Yan, Xiangzhen Ge, Huishan Shen, Gulnazym Ospankulova, Kakimova Zhainagul Kh, Wenhao Li
Summary: The exploration and synthesis of degradable plastics can help address environmental pollution caused by petroleum-based plastics. In this study, a KGM/zein/PVA ternary blend plastic was successfully prepared, and the addition of KGM and zein improved its compatibility and disrupted the molecular and crystalline structure of PVA. The blended plastic with the right proportion of KGM to zein exhibited the best mechanical properties and showed improved degradability compared to pure PVA plastic.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Tao Zhang, Shengjun Chen, Xiaoqi Xu, Xinbo Zhuang, Yinji Chen, Yong Xue, Changhu Xue, Ning Jiang
Summary: This study investigates the internal phase behaviours of proteins and polysaccharides in surimi gel systems and establishes a relationship between dynamic rheology and phase behaviours. The study finds that rheological values of blended systems are linked to phase behaviours. This conjecture is further verified through microscopy and fractal dimension analysis.
FOOD HYDROCOLLOIDS
(2023)
Article
Biochemistry & Molecular Biology
Kao Wu, Yi Wan, Xin Li, Hong Qian, Man Xiao, Xuewen Ni, Fatang Jiang, Sheng Chen
Summary: This study analyzed the impact of heating and drying temperatures on the properties of curdlan and KGM/curdlan blend films, revealing that the addition of KGM improved the film-forming properties of curdlan. High heating temperature enhanced molecular interaction in the films, while drying temperature had different effects on different films.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Kao Wu, Ying Fang, Huaxin Wu, Yi Wan, Hong Qian, Fatang Jiang, Sheng Chen
Summary: The pore size distribution of konjac glucomannan (KGM)-based aerogels plays a key role in air filtration efficiency and resistance. Increasing the total solid concentration leads to smaller pore size and decreased porosity in the aerogels. By preparing aerogel stacks with different pore size distributions, filtration efficiency can be improved while reducing air resistance.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Polymer Science
Ying Kuang, Lijun Chen, Junjun Zhai, Si Zhao, Qinjian Xiao, Kao Wu, Dongling Qiao, Fatang Jiang
Summary: Bio-based aerogels, specifically konjac glucomannan (KGM) based aerogels, were prepared as thermal insulation materials with the addition of wheat straw to reduce pore size and improve flame retardancy. The KGM-based aerogels showed low densities, low thermal conductivities, and high potential for use in heat insulation applications.
Article
Food Science & Technology
Fei Xiang, Yuting Xia, Yan Wang, Yixin Wang, Kao Wu, Xuewen Ni
Summary: This study investigated the effect of incorporating different nanoparticles on KGM-based films, with KGM/zein nanoparticle blend film showing the best properties for cherry tomatoes preservation.
FOOD PACKAGING AND SHELF LIFE
(2021)
Article
Food Science & Technology
Man Xiao, Ling Luo, Bin Tang, Jiaming Qin, Kao Wu, Fatang Jiang
Summary: This study developed a new emulsified film incorporating virgin coconut oil (VCO) into a base of konjac glucomannan (KGM)/agar/gum Arabic (GA), and investigated its effects on physical, structural, and water barrier properties. The addition of VCO had significant effects on the mechanical and water barrier properties of the film. Packed cucumber with the emulsified film showed improved storage quality compared to unpackaged cucumber.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Kao Wu, Xin Li, Xu Yan, Yi Wan, Likun Miao, Man Xiao, Fatang Jiang, Sheng Chen
Summary: The addition of curdlan to KGM/EC films can significantly improve moisture barrier properties and mechanical properties, with the optimal addition amount being 20% of the total weight. Curdlan mainly acts as a filling component in the films, and too low or too high addition amounts can lead to decreased performance.
Article
Agricultural Engineering
Kao Wu, Huaxin Wu, Ru Wang, Xu Yan, Weiwei Sun, Yi Liu, Ying Kuang, Fatang Jiang, Sheng Chen
Summary: The study focused on developing eco-friendly thermal insulation material made of recyclable wastes, specifically polysaccharide-based aerogels with enhanced thermal insulation properties using konjac glucomannan, starch, and office waste paper cellulose fiber. Results showed that increasing the addition of WPCF improved the stability and mechanical properties of aerogels, with optimal thermal conductivity achieved at 0.5 wt% addition of WPCF. Further additions of WPCF led to an increase in thermal conductivity due to enhanced heat conduction and convection.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Food Science & Technology
Man Xiao, Bin Tang, Jiaming Qin, Kao Wu, Fatang Jiang
Summary: The effects of virgin coconut oil (VCO) contents on the properties of corn starch/sodium alginate/gum Arabic composite emulsions and films were investigated. The study found that increased VCO content weakened the emulsion stability and reduced the water vapor permeability and water adsorption of the films.
FOOD PACKAGING AND SHELF LIFE
(2022)
Article
Agricultural Engineering
Kai Chen, Guojuan Xu, Runmiao Tian, Jun Jiang, Ying Kuang, Kao Wu, Fatang Jiang
Summary: The pore size distribution and pore number significantly influenced the air filtration performance of polysaccharide-based aerogels. Konjac glucomannan (KGM)/curdlan (KC) aerogels were prepared by vacuum freeze-drying, and their microstructure, molecular interaction, mechanical property, thermal stability, and air filtration performance were investigated. Results showed that KGM and curdlan had good compatibility and formed a complete aerogel structure. The addition of curdlan decreased the pore size and increased the pore number, resulting in improved filtration efficiency. KC0.9 was considered the optimal material for air filtration based on both filtration efficiency and air resistance.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Biochemistry & Molecular Biology
Kai Chen, Runmiao Tian, Guojuan Xu, Kao Wu, Yi Liu, Fatang Jiang
Summary: In this study, composite coatings (KC) were fabricated using konjac glucomannan (KGM) and curdlan. The rheological properties of the coating solutions were investigated, and the coatings were characterized by various methods. Results showed that the addition of curdlan improved the properties of KGM coatings. The KGM-curdlan composites exhibited good compatibility and uniformity, and the K3C2 coating showed the best performance. The application of K3C2 coating effectively reduced weight loss, decay, and delays in the deterioration of cherry tomatoes.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Kao Wu, Xu Yan, Dandan Zhu, Yuxuan Tao, Yang Zeng, Xin Li, Weiwei Sun, Hong Qian, Fatang Jiang, Sheng Chen
Summary: A hydrophilic konjac glucomannan (KGM)/ hydrophobic ethyl cellulose (EC) film was prepared in an ethanol/water environment. The study found that higher ethanol usage enhanced the stability of the film-forming solution but did not improve the film properties. The ethanol content and evaporation affected the molecular interaction during film formation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Kao Wu, Ru Wang, Zijian Ye, Yuxuan Tao, Huaxin Wu, Weiwei Sun, Junjie Cheng, Ying Kuang, Fatang Jiang, Sheng Chen
Summary: The thermal insulation performance of polysaccharide-based biodegradable aerogels can be improved by combining dual-layer/triple-layer aerogels with lower thermal conductivity. In this study, the triple-layer method was found to be more effective in reducing thermal conductivity by reducing airflow. Thinner outer aerogel layers were preferred, and the thermal conductivity was significantly reduced. The triple-layer aerogel method also improved thermal insulation stability, hardness, and resistance to relative humidity.
JOURNAL OF POROUS MATERIALS
(2023)
Article
Chemistry, Physical
Ying Kuang, Qinjian Xiao, Yichen Yang, Menglong Liu, Xiaosa Wang, Pengpeng Deng, Kao Wu, Yi Liu, Bo Peng, Fatang Jiang, Cao Li
Summary: In this study, alkali-treated zein (AZ) and sodium alginate (SA) were combined to prepare AZ/SA composite particles (ZS) for stabilizing Pickering emulsions. The particle size of ZS decreased significantly after alkali treatment, and ZS with different ratios all had sizes smaller than 80 nm. The 3:1 ratio of AZ/SA showed the best stability for Pickering emulsions at a high oil phase fraction of 75%.
Article
Chemistry, Applied
Ying Kuang, Si Zhao, Puming Liu, Menglong Liu, Kao Wu, Yi Liu, Pengpeng Deng, Cao Li, Fatang Jiang
Summary: This study covalently combined dialdehyde konjac glucomannan (DAK) with casein (CAS) via mild covalent cross-linking, and found that the obtained product, CAS-DAK, could effectively stabilize oil-in-water emulsion and improve the emulsifying property and stability of casein.
FOOD HYDROCOLLOIDS
(2023)
Article
Thermodynamics
Hong Qian, Kao Wu, Yuhang Cheng, Chong Li, Juan Wang, Fatang Jiang
Summary: A novel method was proposed to measure the temperature of the filter material and aroma, with high measurement accuracy and the ability to quickly and accurately obtain the temperature distribution. It was found that the aroma temperature produced by non-combustion heating was significantly higher than that produced by non-flaming combustion. Different aroma delivery intervals also had significant effects on the aroma. This study showed that this novel method could contribute to quality evaluation of filter sticks for aromatherapy products.
INTERNATIONAL JOURNAL OF LOW-CARBON TECHNOLOGIES
(2023)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)