Drug response in association with pharmacogenomics and pharmacomicrobiomics: towards a better personalized medicine

Variants of GRM7 as risk factor and response to antipsychotic therapy in schizophrenia

(2020) Wei Liang et al.   Translational Psychiatry

PredCID: prediction of driver frameshift indels in human cancer

(2020) Zhenyu Yue et al.   BRIEFINGS IN BIOINFORMATICS

Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease

(2019) Sebastiaan P. van Kessel et al.   Nature Communications

The diversity of gut microbiome is associated with favorable responses to anti-PD-1 immunotherapy in Chinese non-small cell lung cancer patients

(2019) Yueping Jin et al.   Journal of Thoracic Oncology

Dissecting genetic factors affecting phenylephrine infusion rates during anesthesia: a genome-wide association study employing EHR data

(2019) Yanfei Zhang et al.   BMC Medicine

A GENETIC VARIANT IN THE BCL2 GENE ASSOCIATES WITH ADALIMUMAB RESPONSE IN HIDRADENITIS SUPPURATIVA CLINICAL TRIALS AND REGULATES EXPRESSION OF BCL2

(2019) Mohan Liu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Prevotella copri is associated with carboplatin-induced gut toxicity

(2019) Chaoheng Yu et al.   Cell Death & Disease

Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points—Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC)

(2018) Thomas O. Bergmeijer et al.   AMERICAN HEART JOURNAL

Human gut microbiome: hopes, threats and promises

(2018) Patrice D Cani   GUT

Microbiota–drug interactions: Impact on metabolism and efficacy of therapeutics

(2018) Ellen M. Wilkinson et al.   MATURITAS

Germline genome-wide association studies in women receiving neoadjuvant chemotherapy with or without bevacizumab

(2018) James N. Ingle et al.   Pharmacogenetics and Genomics

Replicability and Prediction: Lessons and Challenges from GWAS

(2018) Urko M. Marigorta et al.   TRENDS IN GENETICS

The role of the gut microbiome in systemic inflammatory disease

(2018) Jose C Clemente et al.   BMJ-British Medical Journal

Pharmacomicrobiomics: a novel route towards personalized medicine?

(2018) Marwah Doestzada et al.   Protein & Cell

The role of the gut microbiome in systemic inflammatory disease

(2018) Jose C Clemente et al.   BMJ-British Medical Journal

Pathway-Based Analysis of Genome-Wide Association Data Identified SNPs in HMMR as Biomarker for Chemotherapy- Induced Neutropenia in Breast Cancer Patients

(2018) Behzad Bidadi et al.   Frontiers in Pharmacology

Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study

(2018) Daniel B Hawcutt et al.   Lancet Respiratory Medicine

A genome-wide association and admixture mapping study of bronchodilator drug response in African Americans with asthma

(2018) Melissa L. Spear et al.   PHARMACOGENOMICS JOURNAL

Biodegradability of fluoxetine, mefenamic acid, and metoprolol using different microbial consortiums

(2017) Yolanda Flores Velázquez et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

The Female Genital Tract Microbiome Is Associated With Vaginal Antiretroviral Drug Concentrations in Human Immunodeficiency Virus–Infected Women on Antiretroviral Therapy

(2017) Renee Donahue Carlson et al.   JOURNAL OF INFECTIOUS DISEASES

Gut microbiota is critical for the induction of chemotherapy-induced pain

(2017) Shiqian Shen et al.   NATURE NEUROSCIENCE

Gut microbiota modulation of chemotherapy efficacy and toxicity

(2017) James L. Alexander et al.   Nature Reviews Gastroenterology & Hepatology

Genome-wide association study of cardiotoxicity in the NCCTG N9831 (Alliance) adjuvant trastuzumab trial

(2017) Daniel J. Serie et al.   Pharmacogenetics and Genomics

Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response

(2017) Joshua D. Backman et al.   Pharmacogenetics and Genomics

Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population

(2017) Pär Hallberg et al.   PHARMACOGENOMICS

Genome-wide association study identifies the common variants in CYP3A4 and CYP3A5 responsible for variation in tacrolimus trough concentration in Caucasian kidney transplant recipients

(2017) W S Oetting et al.   PHARMACOGENOMICS JOURNAL

Genome-wide association studies of placebo and duloxetine response in major depressive disorder

(2017) M Maciukiewicz et al.   PHARMACOGENOMICS JOURNAL

Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women

(2017) Nichole R. Klatt et al.   SCIENCE

Gut microbiome interactions with drug metabolism, efficacy, and toxicity

(2017) Ian D. Wilson et al.   Translational Research

Introducing the Microbiome into Precision Medicine

(2017) Thomas M. Kuntz et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Genetic variation in human drug-related genes

(2017) Charlotta Pauline Irmgard Schärfe et al.   Genome Medicine

A two-part mixed-effects model for analyzing longitudinal microbiome compositional data

(2016) Eric Z. Chen et al.   BIOINFORMATICS

Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans

(2016) Ron Sender et al.   CELL

Effects of orally administered antibiotics on the bioavailability of amlodipine

(2016) Hye Hyun Yoo et al.   JOURNAL OF HYPERTENSION

TrimethylamineN-Oxide and Cardiovascular Events in Hemodialysis Patients

(2016) Tariq Shafi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The metabolic role of the gut microbiota in health and rheumatic disease: mechanisms and interventions

(2016) Shahla Abdollahi-Roodsaz et al.   Nature Reviews Rheumatology

Response to interferon-beta treatment in multiple sclerosis patients: a genome-wide association study

(2016) S Mahurkar et al.   PHARMACOGENOMICS JOURNAL

The GRM7 gene, early response to risperidone and schizophrenia: a genome-wide association study and a confirmatory pharmacogenetic analysis

(2016) E Sacchetti et al.   PHARMACOGENOMICS JOURNAL

Pharmacogenomics of Drug Metabolizing Enzymes and Transporters: Relevance to Precision Medicine

(2016) Shabbir Ahmed et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Computational approaches in target identification and drug discovery

(2016) Theodora Katsila et al.   Computational and Structural Biotechnology Journal

Advances in computational approaches for prioritizing driver mutations and significantly mutated genes in cancer genomes

(2015) Feixiong Cheng et al.   BRIEFINGS IN BIOINFORMATICS

Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine

(2015) R Kaddurah-Daouk et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

InheritedNUDT15Variant Is a Genetic Determinant of Mercaptopurine Intolerance in Children With Acute Lymphoblastic Leukemia

(2015) Jun J. Yang et al.   JOURNAL OF CLINICAL ONCOLOGY

Metabolism of Rutin and Poncirin by Human Intestinal Microbiota and Cloning of Their Metabolizing ��-L-Rhamnosidase from Bifidobacterium dentium

(2015) Seo-Hyeon Bang et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder

(2015) J Song et al.   MOLECULAR PSYCHIATRY

A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer

(2015) Folefac Aminkeng et al.   NATURE GENETICS

Genome-wide association study of virologic response with efavirenz-containing or abacavir-containing regimens in AIDS clinical trials group protocols

(2015) David S. Lehmann et al.   Pharmacogenetics and Genomics

Genome-wide association study on antipsychotic-induced weight gain in the CATIE sample

(2015) E J Brandl et al.   PHARMACOGENOMICS JOURNAL

A genome-wide association study identifies a new locus associated with the response to anti-TNF therapy in rheumatoid arthritis

(2015) A Julià et al.   PHARMACOGENOMICS JOURNAL

Genome-wide association study of leukotriene modifier response in asthma

(2015) A Dahlin et al.   PHARMACOGENOMICS JOURNAL

A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough

(2015) J D Mosley et al.   PHARMACOGENOMICS JOURNAL

A Multivariate Genome-Wide Association Analysis of 10 LDL Subfractions, and Their Response to Statin Treatment, in 1868 Caucasians

(2015) Heejung Shim et al.   PLoS One

Genetic determinants of antithyroid drug-induced agranulocytosis by human leukocyte antigen genotyping and genome-wide association study

(2015) Pei-Lung Chen et al.   Nature Communications

Transforming berberine into its intestine-absorbable form by the gut microbiota

(2015) Ru Feng et al.   Scientific Reports

A genome-wide association study of antidepressant response in Koreans

(2015) W Myung et al.   Translational Psychiatry

Mycoplasma hyorhinis -encoded cytidine deaminase efficiently inactivates cytosine-based anticancer drugs

(2015) Johan Vande Voorde et al.   FEBS Open Bio

Genome-Wide Association Studies in Africans and African Americans: Expanding the Framework of the Genomics of Human Traits and Disease

(2015) Emmanuel Peprah et al.   Public Health Genomics

Discovery and Characterization of Gut Microbiota Decarboxylases that Can Produce the Neurotransmitter Tryptamine

(2014) Brianna B. Williams et al.   Cell Host & Microbe

Microbial view of central nervous system autoimmunity

(2014) Kerstin Berer et al.   FEBS LETTERS

Effects of Intestinal Microbiota on the Bioavailability of Geniposide in Rats

(2014) Ming Ji Jin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Encapsulation and Micronization Effectively Improve Orange Beverage Flavanone Bioavailability in Humans

(2014) María Tomás-Navarro et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Pharmacomicrobiomics: The Impact of Human Microbiome Variations on Systems Pharmacology and Personalized Therapeutics

(2014) Marwa ElRakaiby et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Genome-wide analysis of methotrexate pharmacogenomics in rheumatoid arthritis shows multiple novel risk variants and leads for TYMS regulation

(2014) Sabyasachi Senapati et al.   Pharmacogenetics and Genomics

Genome-wide association study identifies CAMKID variants involved in blood pressure response to losartan: the SOPHIA study

(2014) Francesca Frau et al.   PHARMACOGENOMICS

Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases

(2014) J Cobb et al.   PHARMACOGENOMICS JOURNAL

Novel Gut-Based Pharmacology of Metformin in Patients with Type 2 Diabetes Mellitus

(2014) Antonella Napolitano et al.   PLoS One

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

(2014) Iris Postmus et al.   Nature Communications

Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan

(2013) Siew-Kee Low et al.   CANCER SCIENCE

The human microbiome is a source of therapeutic drug targets

(2013) Bret D Wallace et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A genome-wide association study of bronchodilator response in Latinos implicates rare variants

(2013) Katherine A. Drake et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Genetic and chemical characterization of ibuprofen degradation by Sphingomonas Ibu-2

(2013) R. W. Murdoch et al.   MICROBIOLOGY-SGM

Medicines from microbiota

(2013) Bernat Olle   NATURE BIOTECHNOLOGY

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Pharmacogenomics in Alzheimer's disease: a genome-wide association study of response to cholinesterase inhibitors

(2013) Filippo Martinelli-Boneschi et al.   NEUROBIOLOGY OF AGING

Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations

(2013) José Antonio Cornejo-García et al.   PHARMACOGENOMICS

Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans

(2013) J L Del-Aguila et al.   PHARMACOGENOMICS JOURNAL

Gut Pharmacomicrobiomics: the tip of an iceberg of complex interactions between drugs and gut-associated microbes

(2013) Rama Saad et al.   Gut Pathogens

Antipsychotics and the gut microbiome: olanzapine-induced metabolic dysfunction is attenuated by antibiotic administration in the rat

(2013) K J Davey et al.   Translational Psychiatry

Genome-wide Association Identifies theTGene as a Novel Asthma Pharmacogenetic Locus

(2012) Kelan G. Tantisira et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Targeting the Human Genome–Microbiome Axis for Drug Discovery: Inspirations from Global Systems Biology and Traditional Chinese Medicine

(2012) Liping Zhao et al.   JOURNAL OF PROTEOME RESEARCH

Genomewide Pharmacogenetics of Bisphosphonate-Induced Osteonecrosis of the Jaw: The Role of RBMS3

(2012) P. Nicoletti et al.   ONCOLOGIST

A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy

(2012) Kazuma Kiyotani et al.   Pharmacogenetics and Genomics

Genome-wide association study of patient-rated and clinician-rated global impression of severity during antipsychotic treatment

(2012) Shaunna L. Clark et al.   Pharmacogenetics and Genomics

A genome-wide association study for irinotecan-related severe toxicities in patients with advanced non-small-cell lung cancer

(2012) J-Y Han et al.   PHARMACOGENOMICS JOURNAL

Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: genome-wide associations and functional genomics

(2012) Y Ji et al.   PHARMACOGENOMICS JOURNAL

The mystery of missing heritability: Genetic interactions create phantom heritability

(2012) O. Zuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters

(2012) Kieran J. Davey et al.   PSYCHOPHARMACOLOGY

Relating human genetic variation to variation in drug responses

(2012) Ashraf G. Madian et al.   TRENDS IN GENETICS

The Effect of Low-Pressure Carbonation on the Heat Inactivation ofEscherichia coli

(2011) Wannaporn KLANGPETCH et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Population diversity and the performance of warfarin dosing algorithms

(2011) Guilherme Suarez-Kurtz   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients

(2011) R. Stephanie Huang et al.   CLINICAL CANCER RESEARCH

Genome-wide Association Study Identifies Variations in 6p21.3 Associated With Nevirapine-Induced Rash

(2011) Soranun Chantarangsu et al.   CLINICAL INFECTIOUS DISEASES

Investigations of Hydrazine Cleavage of Eltrombopag in Humans

(2011) Y. Deng et al.   DRUG METABOLISM AND DISPOSITION

Dietary selenium affects host selenoproteome expression by influencing the gut microbiota

(2011) Marina V. Kasaikina et al.   FASEB JOURNAL

Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles

(2011) M. Isabel Lucena et al.   GASTROENTEROLOGY

Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C

(2011) Yasuhito Tanaka et al.   HUMAN MOLECULAR GENETICS

A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese

(2011) Kazuma Kiyotani et al.   HUMAN MOLECULAR GENETICS

Six-Week Consumption of a Wild Blueberry Powder Drink Increases Bifidobacteria in the Human Gut

(2011) Stefano Vendrame et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Bacteroides uniformis Is a Putative Bacterial Species Associated with the Degradation of the Isoflavone Genistein in Human Feces

(2011) Mathieu Renouf et al.   JOURNAL OF NUTRITION

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

The microbiome and rheumatoid arthritis

(2011) Jose U. Scher et al.   Nature Reviews Rheumatology

HLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans

(2011) Mark McCormack et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genomewide Association betweenGLCCI1and Response to Glucocorticoid Therapy in Asthma

(2011) Kelan G. Tantisira et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genome-wide association study of epirubicin-induced leukopenia in Japanese patients

(2011) Yuvaraj Srinivasan et al.   Pharmacogenetics and Genomics

Genomics of ADME gene expression: mapping expression quantitative trait loci relevant for absorption, distribution, metabolism and excretion of drugs in human liver

(2011) A Schröder et al.   PHARMACOGENOMICS JOURNAL

A whole-genome association study of major determinants for allopurinol-related Stevens–Johnson syndrome and toxic epidermal necrolysis in Japanese patients

(2011) M Tohkin et al.   PHARMACOGENOMICS JOURNAL

Role of Intestinal Bacteria in Gliadin-Induced Changes in Intestinal Mucosa: Study in Germ-Free Rats

(2011) Jana Cinova et al.   PLoS One

Metabolism of cyadox by the intestinal mucosa microsomes and gut flora of swine, and identification of metabolites by high-performance liquid chromatography combined with ion trap/time-of-flight mass spectrometry

(2011) Ning Xu et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Gut microbiome-host interactions in health and disease

(2011) James M Kinross et al.   Genome Medicine

Warfarin maintenance dose in older patients: Higher average dose and wider dose frequency distribution in patients of African ancestry than those of European ancestry

(2010) Candice L. Garwood et al.   BLOOD CELLS MOLECULES AND DISEASES

Arsenic Metabolism by Human Gut Microbiota upon in Vitro Digestion of Contaminated Soils

(2010) Tom Van de Wiele et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

ITPA Polymorphism Affects Ribavirin-Induced Anemia and Outcomes of Therapy—A Genome-Wide Study of Japanese HCV Virus Patients

(2010) Hidenori Ochi et al.   GASTROENTEROLOGY

Global patterns of genetic diversity and signals of natural selection for human ADME genes

(2010) Jing Li et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population

(2010) Takeshi Ozeki et al.   HUMAN MOLECULAR GENETICS

Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells

(2010) Hsin-Jung Wu et al.   IMMUNITY

Genome-Wide Associations and Functional Genomic Studies of Musculoskeletal Adverse Events in Women Receiving Aromatase Inhibitors

(2010) James N. Ingle et al.   JOURNAL OF CLINICAL ONCOLOGY

Genetic Variation in Metabolizing Enzyme and Transporter Genes: Comprehensive Assessment in 3 Major East Asian Subpopulations With Comparison to Caucasians and Africans

(2010) Michael Man et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Genome-Wide Association Study on Overall Survival of Advanced Non-small Cell Lung Cancer Patients Treated with Carboplatin and Paclitaxel

(2010) Yasunori Sato et al.   Journal of Thoracic Oncology

ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C

(2010) Jacques Fellay et al.   NATURE

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury

(2010) Jonathan B Singer et al.   NATURE GENETICS

Genome-wide association studies in pharmacogenomics

(2010) Alison A. Motsinger-Reif et al.   Pharmacogenetics and Genomics

Genome-wide association study of antipsychotic-induced QTc interval prolongation

(2010) K Åberg et al.   PHARMACOGENOMICS JOURNAL

A genome-wide association study identifies new loci for ACE activity: potential implications for response to ACE inhibitor

(2010) C-M Chung et al.   PHARMACOGENOMICS JOURNAL

Genome-Wide and Follow-Up Studies Identify CEP68 Gene Variants Associated with Risk of Aspirin-Intolerant Asthma

(2010) Jeong-Hyun Kim et al.   PLoS One

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Role of pharmacogenomics in drug discovery and development

(2009) C Adithan et al.   INDIAN JOURNAL OF PHARMACOLOGY

Association of Cytochrome P450 2C19 Genotype With the Antiplatelet Effect and Clinical Efficacy of Clopidogrel Therapy

(2009) Alan R. Shuldiner   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Germline Genetic Variation in an Organic Anion Transporter Polypeptide Associated With Methotrexate Pharmacokinetics and Clinical Effects

(2009) Lisa R. Treviño et al.   JOURNAL OF CLINICAL ONCOLOGY

A pharmacogenetic study of CD4 recovery in response to HIV antiretroviral therapy in two South African population groups

(2009) John Parathyras et al.   JOURNAL OF HUMAN GENETICS

Anti-inflammatory properties of a pomegranate extract and its metabolite urolithin-A in a colitis rat model and the effect of colon inflammation on phenolic metabolism☆

(2009) Mar Larrosa et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

(2009) Dongliang Ge et al.   NATURE

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy

(2009) Vijayaprakash Suppiah et al.   NATURE GENETICS

Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

(2009) Yasuhito Tanaka et al.   NATURE GENETICS

Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism

(2009) T. A. Clayton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Genetic Structure and History of Africans and African Americans

(2009) S. A. Tishkoff et al.   SCIENCE

Genome-wide association studies in pharmacogenomics: untapped potential for translation

(2009) Idris Guessous et al.   Genome Medicine

A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose

(2009) Fumihiko Takeuchi et al.   PLoS Genetics

African Genetic Diversity: Implications for Human Demographic History, Modern Human Origins, and Complex Disease Mapping

(2008) Michael C. Campbell et al.   Annual Review of Genomics and Human Genetics

The Role of Ethnicity in Variability in Response to Drugs: Focus on Clinical Pharmacology Studies

(2008) SU Yasuda et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Effectiveness of antiretroviral therapy among HIV-infected children in sub-Saharan Africa

(2008) Catherine G Sutcliffe et al.   LANCET INFECTIOUS DISEASES

Pharmacogenetics in drug discovery and development: a translational perspective

(2008) Allen D. Roses   NATURE REVIEWS DRUG DISCOVERY

Gut microbiota: a potential new territory for drug targeting

(2008) Wei Jia et al.   NATURE REVIEWS DRUG DISCOVERY