Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

Integrative eQTL-Based Analyses Reveal the Biology of Breast Cancer Risk Loci

(2013) Qiyuan Li et al.   CELL

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

(2013) Bin Zhang et al.   CELL

Expression Quantitative Trait Loci Analysis Identifies Associations Between Genotype and Gene Expression in Human Intestine

(2013) Boyko Kabakchiev et al.   GASTROENTEROLOGY

A cross-platform analysis of 14,177 expression quantitative trait loci derived from lymphoblastoid cell lines

(2013) L. Liang et al.   GENOME RESEARCH

Levels of Cholesterol in Small LDL Particles Predict Atherosclerosis Progression and Incident CHD in the HDL-Atherosclerosis Treatment Study (HATS)

(2013) Paul T. Williams et al.   PLoS One

Identification of Single Nucleotide Polymorphisms Regulating Peripheral Blood mRNA Expression with Genome-Wide Significance: An eQTL Study in the Japanese Population

(2013) Daimei Sasayama et al.   PLoS One

Genetic Determinants of Statin-Induced Low-Density Lipoprotein Cholesterol Reduction

(2012) Daniel I. Chasman et al.   Circulation-Cardiovascular Genetics

The Clinical Pharmacogenomics Implementation Consortium: CPIC Guideline for SLCO1B1 and Simvastatin-Induced Myopathy

(2012) R A Wilke et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study

(2012) Jemma C. Hopewell et al.   EUROPEAN HEART JOURNAL

Impact of common regulatory single-nucleotide variants on gene expression profiles in whole blood

(2012) Divya Mehta et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes

(2012) Darren A. Cusanovich et al.   HUMAN MOLECULAR GENETICS

Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism

(2012) Alanna Strong et al.   JOURNAL OF CLINICAL INVESTIGATION

Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a)

(2012) Harshal A. Deshmukh et al.   JOURNAL OF LIPID RESEARCH

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles

(2012) Benjamin P Fairfax et al.   NATURE GENETICS

Mapping cis- and trans-regulatory effects across multiple tissues in twins

(2012) Elin Grundberg et al.   NATURE GENETICS

Pharmacogenetics of statins: achievements, whole-genome analyses and future perspectives

(2012) Iris Postmus et al.   PHARMACOGENOMICS

Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection

(2012) L. B. Barreiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lung eQTLs to Help Reveal the Molecular Underpinnings of Asthma

(2012) Ke Hao et al.   PLoS Genetics

Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants

(2012) Fanggeng Zou et al.   PLoS Genetics

Effects of the PPAR-δ agonist MBX-8025 on atherogenic dyslipidemia

(2011) Yun-Jung Choi et al.   ATHEROSCLEROSIS

Co-regulatory expression quantitative trait loci mapping: method and application to endometrial cancer

(2011) Kenneth S Kompass et al.   BMC Medical Genomics

Genetic variants, plasma lipoprotein(a) levels, and risk of cardiovascular morbidity and mortality among two prospective cohorts of type 2 diabetes

(2011) Qibin Qi et al.   EUROPEAN HEART JOURNAL

A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort

(2011) D. M. Greenawalt et al.   GENOME RESEARCH

Temporal dynamics and genetic control of transcription in the human prefrontal cortex

(2011) Carlo Colantuoni et al.   NATURE

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Organic Anion Transporting Polypeptide 1B1: a Genetically Polymorphic Transporter of Major Importance for Hepatic Drug Uptake

(2011) M. Niemi et al.   PHARMACOLOGICAL REVIEWS

MicroRNA Expression in Abdominal and Gluteal Adipose Tissue Is Associated with mRNA Expression Levels and Partly Genetically Driven

(2011) Mattias Rantalainen et al.   PLoS One

Population differences in microRNA expression and biological implications

(2011) R. Stephanie Huang et al.   RNA Biology

Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue

(2011) Federico Innocenti et al.   PLoS Genetics

Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA

(2011) Rudolf S. N. Fehrmann et al.   PLoS Genetics

Gene Expression in Skin and Lymphoblastoid Cells: Refined Statistical Method Reveals Extensive Overlap in cis-eQTL Signals

(2010) Jun Ding et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Common Nonsynonymous Substitutions in SLCO1B1 Predispose to Statin Intolerance in Routinely Treated Individuals With Type 2 Diabetes: A Go-DARTS Study

(2010) L A Donnelly et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes

(2010) Amy Murphy et al.   HUMAN MOLECULAR GENETICS

Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials

(2010)   LANCET

Unknown

(2010) Gie Ken-Dror et al.   MOLECULAR MEDICINE

Whole-genome association mapping of gene expression in the human prefrontal cortex

(2010) C Liu et al.   MOLECULAR PSYCHIATRY

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

(2010) Kiran Musunuru et al.   NATURE

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

The NIH Roadmap Epigenomics Mapping Consortium

(2010) Bradley E Bernstein et al.   NATURE BIOTECHNOLOGY

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Association of Lipid-Lowering Response to Statins in Combined Study Populations

(2010) Mathew J. Barber et al.   PLoS One

Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility

(2010) Tanja Zeller et al.   PLoS One

Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain

(2010) J. Raphael Gibbs et al.   PLoS Genetics

Genetic Control of Human Brain Transcript Expression in Alzheimer Disease

(2009) Jennifer A. Webster et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Complex nature of SNP genotype effects on gene expression in primary human leucocytes

(2009) Graham A Heap et al.   BMC Medical Genomics

Comprehensive Whole-Genome and Candidate Gene Analysis for Response to Statin Therapy in the Treating to New Targets (TNT) Cohort

(2009) John F. Thompson et al.   Circulation-Cardiovascular Genetics

Comprehensive Analysis of Genomic Variation in the LPA Locus and Its Relationship to Plasma Lipoprotein(a) in South Asians, Chinese, and European Caucasians

(2009) Matthew B. Lanktree et al.   Circulation-Cardiovascular Genetics

Population genomics in a disease targeted primary cell model

(2009) E. Grundberg et al.   GENOME RESEARCH

Geographical genomics of human leukocyte gene expression variation in southern Morocco

(2009) Youssef Idaghdour et al.   NATURE GENETICS

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Common Regulatory Variation Impacts Gene Expression in a Cell Type-Dependent Manner

(2009) A. S. Dimas et al.   SCIENCE

Genetics of gene expression and its effect on disease

(2008) Valur Emilsson et al.   NATURE

Genome-wide analysis of transcript isoform variation in humans

(2008) Tony Kwan et al.   NATURE GENETICS

SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

Mapping the Genetic Architecture of Gene Expression in Human Liver

(2008) Eric E Schadt et al.   PLOS BIOLOGY

Distinct Roles for Arp2/3 Regulators in Actin Assembly and Endocytosis

(2007) Brian J Galletta et al.   PLOS BIOLOGY