Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine

Is a Diabetes Mellitus-Linked Amino Acid Signature Associated With  -Blocker-Induced Impaired Fasting Glucose?

(2014) R. M. Cooper-DeHoff et al.   Circulation-Cardiovascular Genetics

Integration of Pharmacometabolomic and Pharmacogenomic Approaches Reveals Novel Insights Into Antiplatelet Therapy

(2013) J P Lewis et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Purine Pathway Implicated in Mechanism of Resistance to Aspirin Therapy: Pharmacometabolomics-Informed Pharmacogenomics

(2013) L M Yerges-Armstrong et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Cometabolism of Microbes and Host: Implications for Drug Metabolism and Drug-Induced Toxicity

(2013) H Li et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pharmacometabolomics: Implications for Clinical Pharmacology and Systems Pharmacology

(2013) R Kaddurah-Daouk et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pharmacometabolomics of Statin Response

(2013) R M Krauss et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pharmacometabolomics Reveals Racial Differences in Response to Atenolol Treatment

(2013) William R. Wikoff et al.   PLoS One

Pharmacometabolomics of Response to Sertraline and to Placebo in Major Depressive Disorder – Possible Role for Methoxyindole Pathway

(2013) Hongjie Zhu et al.   PLoS One

Pharmacometabolomic Signature of Ataxia SCA1 Mouse Model and Lithium Effects

(2013) Bertrand Perroud et al.   PLoS One

Lipidomics Reveals Early Metabolic Changes in Subjects with Schizophrenia: Effects of Atypical Antipsychotics

(2013) Joseph McEvoy et al.   PLoS One

Pharmacometabolomic mapping of early biochemical changes induced by sertraline and placebo

(2013) R Kaddurah-Daouk et al.   Translational Psychiatry

Metabolomics: the apogee of the omics trilogy

(2012) Gary J. Patti et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Merging pharmacometabolomics with pharmacogenomics using ‘1000 Genomes’ single-nucleotide polymorphism imputation

(2012) Ryan Abo et al.   Pharmacogenetics and Genomics

Associations between Purine Metabolites and Clinical Symptoms in Schizophrenia

(2012) Jeffrey K. Yao et al.   PLoS One

Metabolomics Reveals Amino Acids Contribute to Variation in Response to Simvastatin Treatment

(2012) Miles Trupp et al.   PLoS One

Enteric Microbiome Metabolites Correlate with Response to Simvastatin Treatment

(2011) Rima Kaddurah-Daouk et al.   PLoS One

Pretreatment metabotype as a predictor of response to sertraline or placebo in depressed outpatients: a proof of concept

(2011) R Kaddurah-Daouk et al.   Translational Psychiatry

Glycine and a Glycine Dehydrogenase (GLDC) SNP as Citalopram/Escitalopram Response Biomarkers in Depression: Pharmacometabolomics-Informed Pharmacogenomics

(2010) Y Ji et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Stable isotope-resolved metabolomic analysis of lithium effects on glial-neuronal metabolism and interactions

(2010) Teresa W.-M. Fan et al.   Metabolomics

Lipidomic analysis of variation in response to simvastatin in the Cholesterol and Pharmacogenetics Study

(2010) Rima Kaddurah-Daouk et al.   Metabolomics