rs1990622 variant associates with Alzheimer’s disease and regulates TMEM106B expression in human brain tissues
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
rs1990622 variant associates with Alzheimer’s disease and regulates TMEM106B expression in human brain tissues
Authors
Keywords
-
Journal
BMC Medicine
Volume 19, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-01-19
DOI
10.1186/s12916-020-01883-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- rs4147929 variant minor allele increases ABCA7 gene expression and ABCA7 shows increased gene expression in Alzheimer’s disease patients compared with controls
- (2020) Guiyou Liu et al. ACTA NEUROPATHOLOGICA
- Eliciting priors and relaxing the single causal variant assumption in colocalisation analyses
- (2020) Chris Wallace PLoS Genetics
- Loss of TMEM106B leads to myelination deficits: implications for frontotemporal dementia treatment strategies
- (2020) Xiaolai Zhou et al. BRAIN
- Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology
- (2020) Hyun-Sik Yang et al. NEURON
- The impact of sex on gene expression across human tissues
- (2020) Meritxell Oliva et al. SCIENCE
- Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions
- (2020) Solveig K. Sieberts et al. Scientific Data
- Genetic variant rs17185536 regulates SIM1 gene expression in human brain hypothalamus
- (2019) Guiyou Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
- (2019) Brian W. Kunkle et al. NATURE GENETICS
- TMEM106B Effect on cognition in Parkinson disease and frontotemporal dementia
- (2019) Thomas F. Tropea et al. ANNALS OF NEUROLOGY
- Population Difference and Disease Status Affect the Association Between Genetic Variants and Gene Expression
- (2019) Guiyou Liu et al. GASTROENTEROLOGY
- The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion
- (2019) Zeran Li et al. ACTA NEUROPATHOLOGICA
- Rs2293871 regulates HTRA1 expression and affects cerebral small vessel stroke and Alzheimer's disease
- (2019) Guiyou Liu et al. BRAIN
- Exploring lithium’s transcriptional mechanisms of action in bipolar disorder: a multi-step study
- (2019) Ibrahim A. Akkouh et al. NEUROPSYCHOPHARMACOLOGY
- Genetic variants regulate NR1H3 expression and contribute to multiple sclerosis risk
- (2018) Yan Zhang et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- TMEM106B haplotypes have distinct gene expression patterns in aged brain
- (2018) Yingxue Ren et al. Molecular Neurodegeneration
- Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer’s disease
- (2018) Jaeyoon Chung et al. Alzheimers Research & Therapy
- GWAS on family history of Alzheimer’s disease
- (2018) Riccardo E. Marioni et al. Translational Psychiatry
- Alzheimer’s Disease Risk Variant rs2373115 Regulates GAB2 and NARS2 Expression in Human Brain Tissues
- (2018) Guiyou Liu et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Identification of expression quantitative trait loci associated with schizophrenia and affective disorders in normal brain tissue
- (2018) Oneil G. Bhalala et al. PLoS Genetics
- New insights into the role of TREM2 in Alzheimer’s disease
- (2018) Maud Gratuze et al. Molecular Neurodegeneration
- Disease status affects the association between rs4813620 and the expression of Alzheimer’s disease susceptibility geneTRIB3
- (2018) Guiyou Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SORL1 Variants Show Different Association with Early-Onset and Late-Onset Alzheimer’s Disease Risk
- (2017) Guiyou Liu et al. JOURNAL OF ALZHEIMERS DISEASE
- GAB2 rs2373115 variant contributes to Alzheimer's disease risk specifically in European population
- (2017) Yang Hu et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Association analysis of polymorphisms in VMAT2 and TMEM106B genes for Parkinson's disease, amyotrophic lateral sclerosis and multiple system atrophy
- (2017) Tao Hu et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Genetic effects on gene expression across human tissues
- (2017) François Aguet et al. NATURE
- An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome
- (2017) Bernard Ng et al. NATURE NEUROSCIENCE
- Gene-based association study of genes linked to hippocampal sclerosis of aging neuropathology: GRN , TMEM106B , ABCC9 , and KCNMB2
- (2017) Yuriko Katsumata et al. NEUROBIOLOGY OF AGING
- Rs4878104 contributes to Alzheimer’s disease risk and regulates DAPK1 gene expression
- (2017) Yang Hu et al. NEUROLOGICAL SCIENCES
- Autoimmune disease variants regulateGSDMBgene expression in human immune cells and whole blood
- (2017) Yang Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetic variant rs763361 regulates multiple sclerosisCD226gene expression
- (2017) Guiyou Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data
- (2017) Charles C. White et al. PLOS MEDICINE
- Differential Aging Analysis in Human Cerebral Cortex Identifies Variants in TMEM106B and GRN that Regulate Aging Phenotypes
- (2017) Herve Rhinn et al. Cell Systems
- Parkinson's disease-associated genetic variation is linked to quantitative expression of inflammatory genes
- (2017) Steven Pierce et al. PLoS One
- What we know about TMEM106B in neurodegeneration
- (2016) Alexandra M. Nicholson et al. ACTA NEUROPATHOLOGICA
- Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression
- (2016) Frank Soldner et al. NATURE
- Reply to Liu et al.: Translation of rat congenic data to humans on a conserved MHC-III haplotype associated with rheumatoid arthritis
- (2016) Anthony C. Y. Yau et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cis-eQTLs regulate reducedLST1gene andNCR3gene expression and contribute to increased autoimmune disease risk: Table 1.
- (2016) Guiyou Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Comprehensive promoter level expression quantitative trait loci analysis of the human frontal lobe
- (2016) Cornelis Blauwendraat et al. Genome Medicine
- Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease
- (2016) James E. Peters et al. PLoS Genetics
- Alzheimer’s Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci
- (2016) Celeste M. Karch et al. PLoS One
- A novel Alzheimer disease locus located near the gene encoding tau protein
- (2015) G Jun et al. MOLECULAR PSYCHIATRY
- The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
- (2015) et al. SCIENCE
- Analyzing large-scale samples confirms the association between rs16892766 polymorphism and colorectal cancer susceptibility
- (2015) Mingzhi Liao et al. Scientific Reports
- Identifying the Association Between Alzheimer’s Disease and Parkinson’s Disease Using Genome-Wide Association Studies and Protein-Protein Interaction Network
- (2014) Guiyou Liu et al. MOLECULAR NEUROBIOLOGY
- Genetic variability in the regulation of gene expression in ten regions of the human brain
- (2014) Adaikalavan Ramasamy et al. NATURE NEUROSCIENCE
- TMEM106B expression is reduced in Alzheimer’s disease brains
- (2014) Jun-ichi Satoh et al. Alzheimers Research & Therapy
- Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
- (2014) Claudia Giambartolomei et al. PLoS Genetics
- Measles Contributes to Rheumatoid Arthritis: Evidence from Pathway and Network Analyses of Genome-Wide Association Studies
- (2013) Guiyou Liu et al. PLoS One
- Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants
- (2012) Fanggeng Zou et al. PLoS Genetics
- Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy
- (2011) Günter U Höglinger et al. NATURE GENETICS
- Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions
- (2010) Vivianna M Van Deerlin et al. NATURE GENETICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More