TMEM106B Effect on cognition in Parkinson disease and frontotemporal dementia

Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated

(2018) John L Robinson et al.   BRAIN

Progression of Alzheimer’s Disease: A Longitudinal Study in Norwegian Memory Clinics

(2018) Rannveig Sakshaug Eldholm et al.   JOURNAL OF ALZHEIMERS DISEASE

Progression in the LRRK2-Associated Parkinson Disease Population

(2018) Rachel Saunders-Pullman et al.   JAMA Neurology

Global scales for cognitive screening in Parkinson's disease: Critique and recommendations

(2017) Matej Skorvanek et al.   MOVEMENT DISORDERS

Differential Aging Analysis in Human Cerebral Cortex Identifies Variants in TMEM106B and GRN that Regulate Aging Phenotypes

(2017) Herve Rhinn et al.   Cell Systems

Baseline genetic associations in the Parkinson's Progression Markers Initiative (PPMI)

(2015) Mike A. Nalls et al.   MOVEMENT DISORDERS

The TMEM106B locus and TDP-43 pathology in older persons without FTLD

(2015) L. Yu et al.   NEUROLOGY

Hippocampal sclerosis in Lewy body disease is a TDP-43 proteinopathy similar to FTLD-TDP Type A

(2014) Naoya Aoki et al.   ACTA NEUROPATHOLOGICA

Differential clinicopathologic and genetic features of late-onset amnestic dementias

(2014) Melissa E. Murray et al.   ACTA NEUROPATHOLOGICA

TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions

(2014) Michael D. Gallagher et al.   ACTA NEUROPATHOLOGICA

A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank

(2013) Jon B. Toledo et al.   Alzheimers & Dementia

Comparative survey of the topographical distribution of signature molecular lesions in major neurodegenerative diseases

(2013) Steven E. Arnold et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Strikingly Different Clinicopathological Phenotypes Determined by Progranulin-Mutation Dosage

(2012) Katherine R. Smith et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function

(2012) Owen A. Brady et al.   HUMAN MOLECULAR GENETICS

TMEM106B, the Risk Gene for Frontotemporal Dementia, Is Regulated by the microRNA-132/212 Cluster and Affects Progranulin Pathways

(2012) A. S. Chen-Plotkin et al.   JOURNAL OF NEUROSCIENCE

TMEM106B risk variant is implicated in the pathologic presentation of Alzheimer disease

(2012) N. J. Rutherford et al.   NEUROLOGY

The Parkinson Progression Marker Initiative (PPMI)

(2011) Kenneth Marek et al.   PROGRESS IN NEUROBIOLOGY

Risk genotypes at TMEM106B are associated with cognitive impairment in amyotrophic lateral sclerosis

(2010) Ryan Vass et al.   ACTA NEUROPATHOLOGICA

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

(2010) Vivianna M Van Deerlin et al.   NATURE GENETICS

TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers

(2010) N. Finch et al.   NEUROLOGY

The Sydney multicenter study of Parkinson's disease: The inevitability of dementia at 20 years

(2008) Mariese A. Hely et al.   MOVEMENT DISORDERS