Measles Contributes to Rheumatoid Arthritis: Evidence from Pathway and Network Analyses of Genome-Wide Association Studies

Association of Variants inIL2RAWith Progression of Joint Destruction in Rheumatoid Arthritis

(2013) R. Knevel et al.   ARTHRITIS AND RHEUMATISM

Effects of the Live Attenuated Measles-Mumps-Rubella Booster Vaccination on Disease Activity in Patients With Juvenile Idiopathic Arthritis

(2013) Marloes W. Heijstek et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

JAK and STAT Signaling Molecules in Immunoregulation and Immune-Mediated Disease

(2012) John J. O'Shea et al.   IMMUNITY

T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and man

(2012) Shimon Sakaguchi et al.   IMMUNOLOGY AND CELL BIOLOGY

Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population

(2012) Yukinori Okada et al.   NATURE GENETICS

GeneCodis3: a non-redundant and modular enrichment analysis tool for functional genomics

(2012) D. Tabas-Madrid et al.   NUCLEIC ACIDS RESEARCH

STRING v9.1: protein-protein interaction networks, with increased coverage and integration

(2012) Andrea Franceschini et al.   NUCLEIC ACIDS RESEARCH

Expression of the autoimmunity associated TNFAIP3 is increased in rheumatoid arthritis but does not differ according to genotype at 6q23

(2012) J. R. Maxwell et al.   RHEUMATOLOGY

Differences in persistence of measles, mumps, rubella, diphtheria and tetanus antibodies between children with rheumatic disease and healthy controls: a retrospective cross-sectional study

(2011) Marloes W Heijstek et al.   ANNALS OF THE RHEUMATIC DISEASES

Genome-wide association study of rheumatoid arthritis in Koreans: Population-specific loci as well as overlap with European susceptibility loci

(2011) Jan Freudenberg et al.   ARTHRITIS AND RHEUMATISM

The JAK inhibitor tofacitinib regulates synovitis through inhibition of interferon-γ and interleukin-17 production by human CD4+ T cells

(2011) Keisuke Maeshima et al.   ARTHRITIS AND RHEUMATISM

T cell receptor (TCR) signal strength controls arthritis severity in proteoglycan-specific TCR transgenic mice

(2011) K. Olasz et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Genetics of rheumatoid arthritis: time for a change!

(2011) René de Vries   CURRENT OPINION IN RHEUMATOLOGY

Pathway-driven gene stability selection of two rheumatoid arthritis GWAS identifies and validates new susceptibility genes in receptor mediated signalling pathways

(2011) Hariklia Eleftherohorinou et al.   HUMAN MOLECULAR GENETICS

Tyk2 deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice

(2011) M. Ishizaki et al.   INTERNATIONAL IMMUNOLOGY

Pathway-based analysis of GWAS datasets: effective but caution required

(2011) Peilin Jia et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

(2011) Mourad Matmati et al.   NATURE GENETICS

A New Methodology to Associate SNPs with Human Diseases According to Their Pathway Related Context

(2011) Burcu Bakir-Gungor et al.   PLoS One

Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data

(2011) Joanne H Wang et al.   Genome Medicine

Genome-Wide Meta-Analysis Identifies Regions on 7p21 (AHR) and 15q24 (CYP1A2) As Determinants of Habitual Caffeine Consumption

(2011) Marilyn C. Cornelis et al.   PLoS Genetics

Meta-Analysis of Genome-Wide Association Studies in Celiac Disease and Rheumatoid Arthritis Identifies Fourteen Non-HLA Shared Loci

(2011) Alexandra Zhernakova et al.   PLoS Genetics

A Versatile Gene-Based Test for Genome-wide Association Studies

(2010) Jimmy Z. Liu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Identification of the oxidative stress-related gene MSRA as a rheumatoid arthritis susceptibility locus by genome-wide pathway analysis

(2010) Jose-Ezequiel Martín et al.   ARTHRITIS AND RHEUMATISM

Sustained T cell Rap1 signaling is protective in the collagen-induced arthritis model of rheumatoid arthritis

(2010) Joana R. F. Abreu et al.   ARTHRITIS AND RHEUMATISM

Selective functional inhibition of JAK-3 is sufficient for efficacy in collagen-induced arthritis in mice

(2010) Tsung H. Lin et al.   ARTHRITIS AND RHEUMATISM

Genome-wide gene and pathway analysis

(2010) Li Luo et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

(2010) Eli A Stahl et al.   NATURE GENETICS

The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored

(2010) D. Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

A genetic perspective on coeliac disease

(2010) Gosia Trynka et al.   TRENDS IN MOLECULAR MEDICINE

Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance

(2010) Jade E Hollis-Moffatt et al.   ARTHRITIS RESEARCH & THERAPY

Diverse Genome-wide Association Studies Associate the IL12/IL23 Pathway with Crohn Disease

(2009) Kai Wang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

No evidence for association of the KLF12 gene with rheumatoid arthritis in a large UK cohort

(2009) S. Eyre et al.   ANNALS OF THE RHEUMATIC DISEASES

ThePRL-1149 G/T polymorphism and rheumatoid arthritis susceptibility

(2009) Yvonne C. Lee et al.   ARTHRITIS AND RHEUMATISM

Confirmation ofSTAT4,IL2/IL21, andCTLA4polymorphisms in rheumatoid arthritis

(2009) Nina A. Daha et al.   ARTHRITIS AND RHEUMATISM

Using genome-wide pathway analysis to unravel the etiology of complex diseases

(2009) Clara C. Elbers et al.   GENETIC EPIDEMIOLOGY

Pathway and network-based analysis of genome-wide association studies in multiple sclerosis

(2009) S. E. Baranzini et al.   HUMAN MOLECULAR GENETICS

Association of Measles Virus with Rheumatoid Arthritis

(2009) B. J. ROSENAU et al.   JOURNAL OF RHEUMATOLOGY

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

(2009) Soumya Raychaudhuri et al.   NATURE GENETICS

REL, encoding a member of the NF-κB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis

(2009) Peter K Gregersen et al.   NATURE GENETICS

Targeting innate immunity protein kinase signalling in inflammation

(2009) Matthias Gaestel et al.   NATURE REVIEWS DRUG DISCOVERY

GeneCodis: interpreting gene lists through enrichment analysis and integration of diverse biological information

(2009) R. Nogales-Cadenas et al.   NUCLEIC ACIDS RESEARCH

Pathway Analysis of GWAS Provides New Insights into Genetic Susceptibility to 3 Inflammatory Diseases

(2009) Hariklia Eleftherohorinou et al.   PLoS One

Synergistic benefit in inflammatory arthritis by targeting I B kinase   and interferon  

(2008) M Corr et al.   ANNALS OF THE RHEUMATIC DISEASES

Genome-wide association study of rheumatoid arthritis in the Spanish population:KLF12as a risk locus for rheumatoid arthritis susceptibility

(2008) Antonio Julià et al.   ARTHRITIS AND RHEUMATISM

Evidence that cytokines play a role in rheumatoid arthritis

(2008) Fionula M. Brennan et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population

(2008) Akari Suzuki et al.   NATURE GENETICS

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

(2008) Soumya Raychaudhuri et al.   NATURE GENETICS