Regulation of SIRT3 on mitochondrial functions and oxidative stress in Parkinson’s disease
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Title
Regulation of SIRT3 on mitochondrial functions and oxidative stress in Parkinson’s disease
Authors
Keywords
Parkinson’s disease, SIRT3, Mitochondria, Reactive oxygen species, Mitochondrial respiratory chain
Journal
BIOMEDICINE & PHARMACOTHERAPY
Volume 132, Issue -, Pages 110928
Publisher
Elsevier BV
Online
2020-10-29
DOI
10.1016/j.biopha.2020.110928
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Note: Only part of the references are listed.- Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway
- (2020) Jae-Hyeon Park et al. Molecular Neurodegeneration
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- (2020) Yuzhe He et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Damage in Mitochondrial DNA Associated with Parkinson's Disease
- (2020) Rebeca Martín-Jiménez et al. DNA AND CELL BIOLOGY
- Cytochrome c phosphorylation: Control of mitochondrial electron transport chain flux and apoptosis
- (2020) Hasini A. Kalpage et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- PGC-1α, Inflammation, and Oxidative Stress: An Integrative View in Metabolism
- (2020) Sergio Rius-Pérez et al. Oxidative Medicine and Cellular Longevity
- Changes in mitochondrial function in patients with neuromyelitis optica; correlations with motor and cognitive disabilities
- (2020) Forough Foolad et al. PLoS One
- SIRT3 and GCN5L regulation of NADP+- and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2
- (2020) Katarína Smolková et al. Scientific Reports
- Bibliometrics and Visualization of the Mechanisms of Parkinson's Diseases based on Animal Models
- (2020) Yan-Qiu Wang et al. Endocrine Metabolic & Immune Disorders-Drug Targets
- Beyond the Warburg Effect: N-Myc Contributes to Metabolic Reprogramming in Cancer Cells
- (2020) Go J. Yoshida Frontiers in Oncology
- Possible Adverse Effects of High-Dose Nicotinamide: Mechanisms and Safety Assessment
- (2020) Eun Seong Hwang et al. Biomolecules
- An Update on Mitochondrial Reactive Oxygen Species Production
- (2020) Ryan J. Mailloux Antioxidants
- Interplay between NADH oxidation by complex I, glutathione redox state and sirtuin-3, and its role in the development of insulin resistance
- (2020) Christian Cortés-Rojo et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The new role of F1Fo ATP synthase in mitochondria-mediated neurodegeneration and neuroprotection
- (2020) Nelli Mnatsakanyan et al. EXPERIMENTAL NEUROLOGY
- Mitochondria, OxPhos, and neurodegeneration: cells are not just running out of gas
- (2019) Estela Area-Gomez et al. JOURNAL OF CLINICAL INVESTIGATION
- Sirtuin 3 silencing impairs mitochondrial biogenesis and metabolism in colon cancer cells
- (2019) Margalida Torrens-Mas et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Alpha-synuclein structure and Parkinson’s disease – lessons and emerging principles
- (2019) Richard M. Meade et al. Molecular Neurodegeneration
- Bioactive phenolic compounds, metabolism and properties: a review on valuable chemical compounds in Scots pine and Norway spruce
- (2019) Sari Metsämuuronen et al. PHYTOCHEMISTRY REVIEWS
- Parkinson’s disease protein DJ-1 regulates ATP synthase protein components to increase neuronal process outgrowth
- (2019) Rongmin Chen et al. Cell Death & Disease
- Cerebral mitochondrial electron transport chain dysfunction in multiple system atrophy and Parkinson’s disease
- (2019) Sandrine C. Foti et al. Scientific Reports
- Exogenous H2S reduces the acetylation levels of mitochondrial respiratory enzymes via regulating the NAD+-SIRT3 pathway in cardiac tissues of db/db mice
- (2019) Yu Sun et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Genetic, epigenetic and biochemical regulation of succinate dehydrogenase function
- (2019) Behrooz Moosavi et al. BIOLOGICAL CHEMISTRY
- Parkinson Disease Epidemiology, Pathology, Genetics, and Pathophysiology
- (2019) David K. Simon et al. CLINICS IN GERIATRIC MEDICINE
- Icariin protects rotenone-induced neurotoxicity through induction of SIRT3
- (2019) Ru Zeng et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures
- (2019) Yasir S. Elhassan et al. Cell Reports
- SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer
- (2019) Chenxia He et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sirt3-dependent deacetylation of COX-1 counteracts oxidative stress–induced cell apoptosis
- (2019) Long-Fang Tu et al. FASEB JOURNAL
- NAD + Intermediates: The Biology and Therapeutic Potential of NMN and NR
- (2018) Jun Yoshino et al. Cell Metabolism
- Mitochondrial Dysfunction in Parkinson’s Disease: New Mechanistic Insights and Therapeutic Perspectives
- (2018) Jin-Sung Park et al. Current Neurology and Neuroscience Reports
- Role of mitochondrial ROS in the brain: from physiology to neurodegeneration
- (2018) Plamena R. Angelova et al. FEBS LETTERS
- Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3
- (2018) Sha-Sha Xing et al. MECHANISMS OF AGEING AND DEVELOPMENT
- miR-494-3p modulates the progression of in vitro and in vivo Parkinson’s disease models by targeting SIRT3
- (2018) Lijiao Geng et al. NEUROSCIENCE LETTERS
- Protective and therapeutic activity of honokiol in reversing motor deficits and neuronal degeneration in the mouse model of Parkinson’s disease
- (2018) Hwei-Hsien Chen et al. Pharmacological Reports
- SIRT3 activator Honokiol attenuates β-Amyloid by modulating amyloidogenic pathway
- (2018) Sindhu Ramesh et al. PLoS One
- The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC and Fly Models of Parkinson’s Disease
- (2018) David C. Schöndorf et al. Cell Reports
- Icariin Reduces Dopaminergic Neuronal Loss and Microglia-Mediated Inflammation in Vivo and in Vitro
- (2018) Guo-Qing Wang et al. Frontiers in Molecular Neuroscience
- Therapeutic effects of honokiol on motor impairment in hemiparkinsonian mice are associated with reversing neurodegeneration and targeting PPARγ regulation
- (2018) Hwei-Hsien Chen et al. BIOMEDICINE & PHARMACOTHERAPY
- The Role of SIRT3 in the Brain Under Physiological and Pathological Conditions
- (2018) Elena Sidorova-Darmos et al. Frontiers in Cellular Neuroscience
- Acetylation of Mitochondrial Proteins in the Heart: The Role of SIRT3
- (2018) Rebecca M. Parodi-Rullán et al. Frontiers in Physiology
- Cellular and Molecular Aspects of Parkinson Treatment: Future Therapeutic Perspectives
- (2018) Khosro Jamebozorgi et al. MOLECULAR NEUROBIOLOGY
- SIRT3 deficiency-induced mitochondrial dysfunction and inflammasome formation in the brain
- (2018) Alpna Tyagi et al. Scientific Reports
- Functional and therapeutic potential of mitochondrial SIRT3 deacetylase in disease conditions
- (2018) Abhinav Kanwal Expert Review of Clinical Pharmacology
- In vivo ROS production and use of oxidative stress-derived biomarkers to detect the onset of diseases such as Alzheimer’s disease, Parkinson’s disease, and diabetes
- (2017) Aya Umeno et al. FREE RADICAL RESEARCH
- Sirt3 protects dopaminergic neurons from mitochondrial oxidative stress
- (2017) Han Shi et al. HUMAN MOLECULAR GENETICS
- Mitochondrial SIRT3 and neurodegenerative brain disorders
- (2017) Anamika et al. JOURNAL OF CHEMICAL NEUROANATOMY
- NAD and the aging process: Role in life, death and everything in between
- (2017) Claudia C.S. Chini et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant α-synuclein rat model of parkinsonism
- (2017) Jacqueline A. Gleave et al. NEUROBIOLOGY OF DISEASE
- SIRT3 Enhances Mesenchymal Stem Cell Longevity and Differentiation
- (2017) Ryan A. Denu Oxidative Medicine and Cellular Longevity
- Neuroprotective properties of icariin in MPTP-induced mouse model of Parkinson's disease: Involvement of PI3K/Akt and MEK/ERK signaling pathways
- (2017) Wen-Fang Chen et al. PHYTOMEDICINE
- Genetic Forms of Parkinson's Disease
- (2017) Christine Kim et al. SEMINARS IN NEUROLOGY
- Mitochondrial Complex II: At the Crossroads
- (2017) Ayenachew Bezawork-Geleta et al. TRENDS IN BIOCHEMICAL SCIENCES
- Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice
- (2017) Vinodkumar B. Pillai et al. Oncotarget
- Neuropathological Staging of Brain Pathology in Sporadic Parkinson’s disease: Separating the Wheat from the Chaff
- (2017) Heiko Braak et al. Journal of Parkinsons Disease
- Studies on the regulatory mechanism of isocitrate dehydrogenase 2 using acetylation mimics
- (2017) Yuqun Xu et al. Scientific Reports
- Function of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative disease
- (2016) Aneesa Ansari et al. AGING CELL
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- (2016) Xiaonan Wang et al. BRAIN RESEARCH
- Preserved recovery of cardiac function following ischemia–reperfusion in mice lacking SIRT3
- (2016) Christoph Koentges et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice
- (2016) Kathryn F. Mills et al. Cell Metabolism
- Resveratrol attenuates oxidative stress in mitochondrial Complex I deficiency: Involvement of SIRT3
- (2016) Lise Mathieu et al. FREE RADICAL BIOLOGY AND MEDICINE
- SIRT3 Acts as a Neuroprotective Agent in Rotenone-Induced Parkinson Cell Model
- (2016) Jing-Yi Zhang et al. NEUROCHEMICAL RESEARCH
- NAD+ as the Link Between Oxidative Stress, Inflammation, Caloric Restriction, Exercise, DNA Repair, Longevity, and Health Span
- (2016) Borut Poljsak et al. REJUVENATION RESEARCH
- Activation of SIRT3 attenuates triptolide-induced toxicity through closing mitochondrial permeability transition pore in cardiomyocytes
- (2016) Yanqin Yang et al. TOXICOLOGY IN VITRO
- Mechanisms and Dynamics of Protein Acetylation in Mitochondria
- (2016) Josue Baeza et al. TRENDS IN BIOCHEMICAL SCIENCES
- Environmental Exposures and Parkinson’s Disease
- (2016) Sirisha Nandipati et al. International Journal of Environmental Research and Public Health
- Nicotinamide N-methyltransferase increases complex I activity in SH-SY5Y cells via sirtuin 3
- (2015) Karolina Y. Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Lysine Acetylation Activates Mitochondrial Aconitase in the Heart
- (2015) Jolyn Fernandes et al. BIOCHEMISTRY
- The role of mitochondrial dysfunction in age-related diseases
- (2015) Rebecca K. Lane et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Design, synthesis and structure–activity relationship studies of novel sirtuin 2 (SIRT2) inhibitors with a benzamide skeleton
- (2015) Taki Sakai et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer’s disease-relevant murine model
- (2015) Aaron N Long et al. BMC Neurology
- SIRT3 Deacetylates Ceramide Synthases
- (2015) Sergei A. Novgorodov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SIRT3 Attenuates MPTP-Induced Nigrostriatal Degeneration Via Enhancing Mitochondrial Antioxidant Capacity
- (2015) Lei Liu et al. NEUROCHEMICAL RESEARCH
- Protective Mechanisms of Flavonoids in Parkinson’s Disease
- (2015) Kasthuri Bai Magalingam et al. Oxidative Medicine and Cellular Longevity
- In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences
- (2015) Xiao-Hong Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NAD+ in aging, metabolism, and neurodegeneration
- (2015) E. Verdin SCIENCE
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- (2015) Vinodkumar B. Pillai et al. Nature Communications
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- (2015) Ryan J. Mailloux Redox Biology
- SIRT3 deficiency exacerbates ischemia-reperfusion injury: implication for aged hearts
- (2014) George A. Porter et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells
- (2014) Ozkan Ozden et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
- (2014) Dmitry B. Zorov et al. PHYSIOLOGICAL REVIEWS
- Nicotinamide mononucleotide improves energy activity and survival rate in an in vitro model of Parkinson’s disease
- (2014) LEI LU et al. Experimental and Therapeutic Medicine
- Differential expression of sirtuin family members in the developing, adult, and aged rat brain
- (2014) Elena Sidorova-Darmos et al. Frontiers in Aging Neuroscience
- Modulation of human longevity by SIRT3 single nucleotide polymorphisms in the prospective study “Treviso Longeva (TRELONG)”
- (2013) Diego Albani et al. AGE
- The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling
- (2013) Laurent Mouchiroud et al. CELL
- Nicotinamide riboside, a trace nutrient in foods, is a Vitamin B3 with effects on energy metabolism and neuroprotection
- (2013) Yuling Chi et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage
- (2013) Anne H.H. Tseng et al. FREE RADICAL BIOLOGY AND MEDICINE
- SIRT3: As Simple As It Seems?
- (2013) David B. Lombard et al. GERONTOLOGY
- Neuroprotective Effects of Nicotinamide N -Methyltransferase and its Metabolite 1-Methylnicotinamide
- (2013) Zeinab H. Milani et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models
- (2013) Bing Gong et al. NEUROBIOLOGY OF AGING
- Dysregulation of glucose metabolism is an early event in sporadic Parkinson's disease
- (2013) Laura Dunn et al. NEUROBIOLOGY OF AGING
- Neuroprotective Function of DJ-1 in Parkinson’s Disease
- (2013) Hiroyoshi Ariga et al. Oxidative Medicine and Cellular Longevity
- SIRT3 Reverses Aging-Associated Degeneration
- (2013) Katharine Brown et al. Cell Reports
- Regulation of mitochondrial FoF1ATPase activity by Sirt3-catalyzed deacetylation and its deficiency in human cells harboring 4977bp deletion of mitochondrial DNA
- (2012) Yu-Ting Wu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- SIRT3 regulation of mitochondrial oxidative stress
- (2012) Alexandra S. Bause et al. EXPERIMENTAL GERONTOLOGY
- SIRT3 interacts with the daf-16 homolog FOXO3a in the Mitochondria, as well as increases FOXO3a Dependent Gene expression
- (2012) Kristi Muldoon Jacobs et al. International Journal of Biological Sciences
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- (2012) Wei Yu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome
- (2012) Alexander S. Hebert et al. MOLECULAR CELL
- Distinct Effects of Rotenone, 1-methyl-4-phenylpyridinium and 6-hydroxydopamine on Cellular Bioenergetics and Cell Death
- (2012) Samantha Giordano et al. PLoS One
- Toxic effects of nicotinamide methylation on mouse brain striatum neuronal cells and its relation to manganese
- (2012) Yayoi Mori et al. Environmental Health and Preventive Medicine
- Mitochondrial Dysfunction in Genetic Animal Models of Parkinson's Disease
- (2011) Alzbeta Trancikova et al. ANTIOXIDANTS & REDOX SIGNALING
- Toxin Models of Mitochondrial Dysfunction in Parkinson's Disease
- (2011) Terina N. Martinez et al. ANTIOXIDANTS & REDOX SIGNALING
- Neuroprotective Effect of Kaempferol against a 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Mouse Model of Parkinson's Disease
- (2011) Shen Li et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS
- (2011) Yaohui Chen et al. EMBO REPORTS
- Increased superoxide accumulation in pyruvate dehydrogenase complex deficient fibroblasts
- (2011) Lyudmyla G. Glushakova et al. MOLECULAR GENETICS AND METABOLISM
- Succinate Dehydrogenase Is a Direct Target of Sirtuin 3 Deacetylase Activity
- (2011) Lydia W. S. Finley et al. PLoS One
- Mammalian Sirtuins: Biological Insights and Disease Relevance
- (2010) Marcia C. Haigis et al. Annual Review of Pathology-Mechanisms of Disease
- SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress
- (2010) Hyun-Seok Kim et al. CANCER CELL
- Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction
- (2010) Shinichi Someya et al. CELL
- Icariin attenuates lipopolysaccharide-induced microglial activation and resultant death of neurons by inhibiting TAK1/IKK/NF-κB and JNK/p38 MAPK pathways
- (2010) Ke-Wu Zeng et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Metabolomic Analysis of Livers and Serum from High-Fat Diet Induced Obese Mice
- (2010) Hyun-Jin Kim et al. JOURNAL OF PROTEOME RESEARCH
- Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress
- (2010) Randa Tao et al. MOLECULAR CELL
- Neuroprotection of kaempferol by autophagy in models of rotenone-mediated acute toxicity: possible implications for Parkinson's disease
- (2010) Giuseppe Filomeni et al. NEUROBIOLOGY OF AGING
- Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis
- (2010) Xingxing Kong et al. PLoS One
- Bovine cytochromecoxidase structures enable O2reduction with minimization of reactive oxygens and provide a proton-pumping gate
- (2010) Kazumasa Muramoto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of Succinate Dehydrogenase Activity by SIRT3 in Mammalian Mitochondria
- (2009) Huseyin Cimen et al. BIOCHEMISTRY
- Assimilation of Endogenous Nicotinamide Riboside Is Essential for Calorie Restriction-mediated Life Span Extension inSaccharomyces cerevisiae
- (2009) Shu-Ping Lu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
- (2009) C. Choudhary et al. SCIENCE
- Where in the cell is SIRT3? – functional localization of an NAD+-dependent protein deacetylase
- (2008) William C. Hallows et al. BIOCHEMICAL JOURNAL
- Neuroprotective effect of resveratrol on 6-OHDA-induced Parkinson's disease in rats
- (2008) Feng Jin et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Mitochondrial biogenesis and healthy aging
- (2008) Guillermo López-Lluch et al. EXPERIMENTAL GERONTOLOGY
- A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
- (2008) B.-H. Ahn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Resveratrol, a red wine polyphenol, protects dopaminergic neurons in MPTP-treated mice
- (2008) Julie Blanchet et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
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