Beyond the Warburg Effect: N-Myc Contributes to Metabolic Reprogramming in Cancer Cells
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Title
Beyond the Warburg Effect: N-Myc Contributes to Metabolic Reprogramming in Cancer Cells
Authors
Keywords
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Journal
Frontiers in Oncology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-05-28
DOI
10.3389/fonc.2020.00791
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Note: Only part of the references are listed.- Lipid desaturation-associated endoplasmic reticulum stress regulates MYCN gene expression in hepatocellular carcinoma cells
- (2020) Xian-Yang Qin et al. Cell Death & Disease
- Serine–glycine-one-carbon metabolism: vulnerabilities in MYCN-amplified neuroblastoma
- (2020) Erhu Zhao et al. Oncogenesis
- Small molecule inhibitor of c-Myc 10058-F4 inhibits proliferation and induces apoptosis in acute leukemia cells, irrespective of PTEN status
- (2019) Davood Bashash et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Metabolic reprogramming by MYCN confers dependence on the serine-glycine-one-carbon biosynthetic pathway
- (2019) Yingfeng Xia et al. CANCER RESEARCH
- Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies
- (2019) Go J. Yoshida et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- SCD1 regulates the AMPK/SIRT1 pathway and histone acetylation through changes in adenine nucleotide metabolism in skeletal muscle
- (2019) Anna Dziewulska et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Glutaminolysis‐related genes determine sensitivity to xCT‐targeted therapy in head and neck squamous cell carcinoma
- (2019) Shogo Okazaki et al. CANCER SCIENCE
- Glycine decarboxylase is a transcriptional target of MYCN required for neuroblastoma cell proliferation and tumorigenicity
- (2019) Ahmet Alptekin et al. ONCOGENE
- Prevention of hepatocellular carcinoma by targeting MYCN-positive liver cancer stem cells with acyclic retinoid
- (2018) Xian-Yang Qin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- How to eliminate MYCN-positive hepatic cancer stem cells to prevent the recurrence?
- (2018) Go J. Yoshida PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Expanding World of N-MYC–Driven Tumors
- (2018) David S. Rickman et al. Cancer Discovery
- Cancer stem cells of hepatocellular carcinoma
- (2018) Kewei Wang et al. Oncotarget
- The Role for Myc in Coordinating Glycolysis, Oxidative Phosphorylation, Glutaminolysis, and Fatty Acid Metabolism in Normal and Neoplastic Tissues
- (2018) Eric S. Goetzman et al. Frontiers in Endocrinology
- Emerging roles of Myc in stem cell biology and novel tumor therapies
- (2018) Go J. Yoshida JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism
- (2017) Weinan Du et al. Nature Communications
- An Overview of Lipid Droplets in Cancer and Cancer Stem Cells
- (2017) L. Tirinato et al. Stem Cells International
- Glutamine Transport and Mitochondrial Metabolism in Cancer Cell Growth
- (2017) Mariafrancesca Scalise et al. Frontiers in Oncology
- N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer
- (2016) Etienne Dardenne et al. CANCER CELL
- N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells
- (2016) John K. Lee et al. CANCER CELL
- Metabolome Analyses Uncovered a Novel Inhibitory Effect of Acyclic Retinoid on Aberrant Lipogenesis in a Mouse Diethylnitrosamine-Induced Hepatic Tumorigenesis Model
- (2016) X.-Y. Qin et al. Cancer Prevention Research
- Mitochondria and Cancer
- (2016) Sejal Vyas et al. CELL
- The Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress
- (2016) W. Rozpedek et al. CURRENT MOLECULAR MEDICINE
- The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic stem cells
- (2016) Bryan King et al. NATURE IMMUNOLOGY
- Liver cancer stem cell markers: Progression and therapeutic implications
- (2016) Jing-Hui Sun et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Deregulated Myc Requires MondoA/Mlx for Metabolic Reprogramming and Tumorigenesis
- (2015) Patrick A. Carroll et al. CANCER CELL
- Therapeutic strategies targeting cancer stem cells
- (2015) Go J. Yoshida et al. CANCER SCIENCE
- Metabolic reprogramming: the emerging concept and associated therapeutic strategies
- (2015) Go J. Yoshida JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance
- (2015) Dohoon Kim et al. NATURE
- ATF4 and N-Myc coordinate glutamine metabolism inMYCN-amplified neuroblastoma cells through ASCT2 activation
- (2014) Ping Ren et al. JOURNAL OF PATHOLOGY
- MondoA senses adenine nucleotides: transcriptional induction of thioredoxin-interacting protein
- (2013) Kyoung-Sim Han et al. BIOCHEMICAL JOURNAL
- Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target
- (2013) Luika A. Timmerman et al. CANCER CELL
- Proteomic and Lipidomic Signatures of Lipid Metabolism in NASH-Associated Hepatocellular Carcinoma
- (2013) K. Muir et al. CANCER RESEARCH
- Cellular Fatty Acid Metabolism and Cancer
- (2013) Erin Currie et al. Cell Metabolism
- New Strategies in Neuroblastoma: Therapeutic Targeting of MYCN and ALK
- (2013) G. Barone et al. CLINICAL CANCER RESEARCH
- The Effect of Acyclic Retinoid on the Metabolomic Profiles of Hepatocytes and Hepatocellular Carcinoma Cells
- (2013) Xian-Yang Qin et al. PLoS One
- MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells
- (2013) H. Zirath et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Control of Vertebrate Development by MYC
- (2013) P. J. Hurlin Cold Spring Harbor Perspectives in Medicine
- Coordination of Nutrient Availability and Utilization by MAX- and MLX-Centered Transcription Networks
- (2013) J. M. O'Shea et al. Cold Spring Harbor Perspectives in Medicine
- ATF4 Regulates MYC-Mediated Neuroblastoma Cell Death upon Glutamine Deprivation
- (2012) Guoliang Qing et al. CANCER CELL
- Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis
- (2012) Wen Cai Zhang et al. CELL
- Molecular Pathways: Tumor Cells Co-opt the Brain-Specific Metabolism Gene CPT1C to Promote Survival
- (2012) P. T. Reilly et al. CLINICAL CANCER RESEARCH
- CCT244747 Is a Novel Potent and Selective CHK1 Inhibitor with Oral Efficacy Alone and in Combination with Genotoxic Anticancer Drugs
- (2012) M. I. Walton et al. CLINICAL CANCER RESEARCH
- HIF2α Acts as an mTORC1 Activator through the Amino Acid Carrier SLC7A5
- (2012) Ainara Elorza et al. MOLECULAR CELL
- CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth
- (2011) Takatsugu Ishimoto et al. CANCER CELL
- Inhibition of stearoyl-CoA desaturase1 activates AMPK and exhibits beneficial lipid metabolic effects in vitro
- (2011) Eunha Kim et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- miR-126 inhibits proliferation of small cell lung cancer cells by targeting SLC7A5
- (2011) Edit Miko et al. FEBS LETTERS
- Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress
- (2011) K. Zaugg et al. GENES & DEVELOPMENT
- ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug Efflux
- (2011) Michelle J. Henderson et al. JNCI-Journal of the National Cancer Institute
- The MRE11 complex: starting from the ends
- (2011) Travis H. Stracker et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma
- (2011) K. A. Cole et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the “reverse Warburg effect”: A transcriptional informatics analysis with validation
- (2010) Stephanos Pavlides et al. CELL CYCLE
- Glutamine addiction: a new therapeutic target in cancer
- (2010) David R. Wise et al. TRENDS IN BIOCHEMICAL SCIENCES
- Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy
- (2009) Paul Nicklin et al. CELL
- Glutamine-dependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity
- (2009) M. R. Kaadige et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Malonyl-CoA, a Key Signaling Molecule in Mammalian Cells
- (2008) David Saggerson Annual Review of Nutrition
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features
- (2008) Taro Yamashita et al. GASTROENTEROLOGY
- Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
- (2008) D. R. Wise et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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