Commensal microbes and p53 in cancer progression

Genomic basis for RNA alterations in cancer

(2020) Claudia Calabrese et al.   NATURE

Gut Bacteria Composition Drives Primary Resistance to Cancer Immunotherapy in Renal Cell Carcinoma Patients

(2020) Lisa Derosa et al.   EUROPEAN UROLOGY

Addition of Primary Metastatic Site on Bone, Brain, and Liver to IMDC Criteria in Patients With Metastatic Renal Cell Carcinoma: A Validation Study

(2020) Francesco Massari et al.   Clinical Genitourinary Cancer

The role of gut microbiota in cancer treatment: friend or foe?

(2020) Wing Yin Cheng et al.   GUT

The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic

(2020) Eliran Kadosh et al.   NATURE

Targeting p53 for the treatment of cancer

(2020) Michael J. Duffy et al.   SEMINARS IN CANCER BIOLOGY

A user guide for the online exploration and visualization of PCAWG data

(2020) Mary J. Goldman et al.   Nature Communications

Gastric cancer

(2020) Elizabeth C Smyth et al.   LANCET

The Gut Microbiome Associates with Immune Checkpoint Inhibition Outcomes in Patients with Advanced Non–Small Cell Lung Cancer

(2020) Taiki Hakozaki et al.   Cancer Immunology Research

Enhancing folic acid metabolism suppresses defects associated with loss of Drosophila mitofusin

(2019) Juan Garrido-Maraver et al.   Cell Death & Disease

Enrichment of oral microbiota in early cystic precursors to invasive pancreatic cancer

(2019) Rogier Aäron Gaiser et al.   GUT

Genome and pan-genome analysis to classify emerging bacteria

(2019) Aurélia Caputo et al.   Biology Direct

Integrative analysis based on survival associated co-expression gene modules for predicting Neuroblastoma patients’ survival time

(2019) Yatong Han et al.   Biology Direct

From tumors to species: a SCANDAL hypothesis

(2019) A. Y. Panchin et al.   Biology Direct

Robust pathway-based multi-omics data integration using directed random walks for survival prediction in multiple cancer studies

(2019) So Yeon Kim et al.   Biology Direct

Identification of city specific important bacterial signature for the MetaSUB CAMDA challenge microbiome data

(2019) Alejandro R. Walker et al.   Biology Direct

Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism

(2019) Vayu Maini Rekdal et al.   SCIENCE

The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs

(2019) Anthony T. Virtue et al.   Science Translational Medicine

Integration of molecular features with clinical information for predicting outcomes for neuroblastoma patients

(2019) Yatong Han et al.   Biology Direct

Application of machine learning techniques for creating urban microbial fingerprints

(2019) Feargal Joseph Ryan   Biology Direct

Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes

(2019) Erick Riquelme et al.   CELL

Peptostreptococcus anaerobius promotes colorectal carcinogenesis and modulates tumour immunity

(2019) Xiaohang Long et al.   Nature Microbiology

Environmental metagenome classification for constructing a microbiome fingerprint

(2019) Jolanta Kawulok et al.   Biology Direct

Fingerprinting cities: differentiating subway microbiome functionality

(2019) Chengsheng Zhu et al.   Biology Direct

A novel framework for horizontal and vertical data integration in cancer studies with application to survival time prediction models

(2019) Iliyan Mihaylov et al.   Biology Direct

Inactivation of Mdm2 restores apoptosis proficiency of cooperativity mutant p53 in vivo

(2019) Boris Klimovich et al.   CELL CYCLE

Biomarkers for prostate cancer: prostate-specific antigen and beyond

(2019) Michael J. Duffy   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Do Mutations Turn p53 into an Oncogene?

(2019) Consuelo Pitolli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response

(2019) Mireia Uribe-Herranz et al.   JOURNAL OF CLINICAL INVESTIGATION

p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms

(2019) Consuelo Pitolli et al.   Cancers

Unraveling bacterial fingerprints of city subways from microbiome 16S gene profiles

(2018) Alejandro R. Walker et al.   Biology Direct

Predicting survival times for neuroblastoma patients using RNA-seq expression profiles

(2018) Tyler Grimes et al.   Biology Direct

Multi-omics integration for neuroblastoma clinical endpoint prediction

(2018) Margherita Francescatto et al.   Biology Direct

Profiling microbial strains in urban environments using metagenomic sequencing data

(2018) Moreno Zolfo et al.   Biology Direct

Targeting HAUSP in both p53 wildtype and p53-mutant tumors

(2018) Omid Tavana et al.   CELL CYCLE

ZNF281 inhibits neuronal differentiation and is a prognostic marker for neuroblastoma

(2018) Marco Pieraccioli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut microbiome–mediated bile acid metabolism regulates liver cancer via NKT cells

(2018) Chi Ma et al.   SCIENCE

Increased Abundance of Clostridium and Fusobacterium in Gastric Microbiota of Patients with Gastric Cancer in Taiwan

(2018) Yung-Yu Hsieh et al.   Scientific Reports

Insights into the role of gut microbiota in obesity: pathogenesis, mechanisms, and therapeutic perspectives

(2018) Lijuan Sun et al.   Protein & Cell

P53 enhances apoptosis induced by doxorubicin only under conditions of severe DNA damage

(2018) Ru-Wei Lin et al.   CELL CYCLE

p53 accumulation following cytokinesis failure in the absence of caspase-2

(2018) Yoon Lim et al.   CELL DEATH AND DIFFERENTIATION

MDM2 controls gene expression independently of p53 in both normal and cancer cells

(2018) Giuseppe Arena et al.   CELL DEATH AND DIFFERENTIATION

Darwinian selection of host and bacteria supports emergence of Lamarckian-like adaptation of the system as a whole

(2018) Dino Osmanovic et al.   Biology Direct

Assessment of urban microbiome assemblies with the help of targeted in silico gold standards

(2018) Samuel M. Gerner et al.   Biology Direct

Mutant p53 as a guardian of the cancer cell

(2018) Fiamma Mantovani et al.   CELL DEATH AND DIFFERENTIATION

p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression

(2018) Ivano Amelio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peptostreptococcus anaerobius Induces Intracellular Cholesterol Biosynthesis in Colon Cells to Induce Proliferation and Causes Dysplasia in Mice

(2017) Ho Tsoi et al.   GASTROENTEROLOGY

Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine

(2017) Leore T. Geller et al.   SCIENCE

SynTarget: an online tool to test the synergetic effect of genes on survival outcome in cancer

(2016) I Amelio et al.   CELL DEATH AND DIFFERENTIATION

Human Microbiome Fusobacterium Nucleatum in Esophageal Cancer Tissue Is Associated with Prognosis

(2016) Kensuke Yamamura et al.   CLINICAL CANCER RESEARCH

Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects

(2016) Romain Daillère et al.   IMMUNITY

p53 in the DNA-Damage-Repair Process

(2016) Ashley B. Williams et al.   Cold Spring Harbor Perspectives in Medicine

Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack

(2015) Chamutal Gur et al.   IMMUNITY

Microbiota organization—a key to understanding CRC development

(2015) Georgina L. Hold et al.   Nature Reviews Gastroenterology & Hepatology

Cancer and the microbiota

(2015) W. S. Garrett   SCIENCE

The p53 family and the hypoxia-inducible factors (HIFs): determinants of cancer progression

(2015) Ivano Amelio et al.   TRENDS IN BIOCHEMICAL SCIENCES

TAp73 promotes anabolism

(2015) Ivano Amelio et al.   Oncotarget

p63 transcriptionally regulates the expression of matrix metallopeptidase 13

(2015) Ivana Celardo et al.   Oncotarget

Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling

(2014) Susann Weissmueller et al.   CELL

MicroRNAs and p63 in epithelial stemness

(2014) E Candi et al.   CELL DEATH AND DIFFERENTIATION

How theTP53Family ProteinsTP63andTP73Contribute to Tumorigenesis: Regulators and Effectors

(2014) Eleonora Candi et al.   HUMAN MUTATION

TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation

(2014) Ivano Amelio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

(2013) Mara Roxana Rubinstein et al.   Cell Host & Microbe

Caspase-1 is a novel target of p63 in tumor suppression

(2013) I Celardo et al.   Cell Death & Disease

R-Spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea

(2013) Olivier Papapietro et al.   Nature Communications

Skn-1a/Oct-11 and ΔNp63α exert antagonizing effects on human keratin expression

(2010) Anna Maria Lena et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fusobacterium nucleatum Outer Membrane Proteins Fap2 and RadD Induce Cell Death in Human Lymphocytes

(2010) C. W. Kaplan et al.   INFECTION AND IMMUNITY

Elevated Expression of the Tyrosine Phosphatase SHP-1 Defines a Subset of High-Grade Breast Tumors

(2010) Luigi Insabato et al.   ONCOLOGY

Mutant p53 Drives Invasion by Promoting Integrin Recycling

(2009) Patricia A.J. Muller et al.   CELL

A Mutant-p53/Smad Complex Opposes p63 to Empower TGFβ-Induced Metastasis

(2009) Maddalena Adorno et al.   CELL

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

(2009) Shaoguang Wu et al.   NATURE MEDICINE

TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity

(2009) Richard Tomasini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

OC1.08.6 NEWLY DIAGNOSED CANCER IN A COHORT OF CROHN'S DISEASE PATIENTS TREATED WITH INFLIXIMAB: A 3 YEARS LONGER FOLLOW UP FROM A MULTICENTER MATCHED-PAIR STUDY

(2008) L. Biancone et al.   DIGESTIVE AND LIVER DISEASE

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

(2008) R. Tomasini et al.   GENES & DEVELOPMENT

The genetics of the p53 pathway, apoptosis and cancer therapy

(2008) Alexei Vazquez et al.   NATURE REVIEWS DRUG DISCOVERY

Transcriptional control of human p53-regulated genes

(2008) Todd Riley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY