ESRRA (estrogen related receptor alpha) is a critical regulator of intestinal homeostasis through activation of autophagic flux via gut microbiota

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Bacteroides vulgatus and Bacteroides dorei Reduce Gut Microbial Lipopolysaccharide Production and Inhibit Atherosclerosis

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The Crohn’s Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy

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Microbial-Based Therapies in the Treatment of Inflammatory Bowel Disease – An Overview of Human Studies

(2019) Paulo José Basso et al.   Frontiers in Pharmacology

Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition

(2019) Tomomi Toubai et al.   Nature Microbiology

The gut mycobiota: insights into analysis, environmental interactions and role in gastrointestinal diseases

(2019) Mathias L. Richard et al.   Nature Reviews Gastroenterology & Hepatology

The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion

(2019) Yu Xia et al.   Autophagy

Emerging views of mitophagy in immunity and autoimmune diseases

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Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5−/− mice

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ERRα as a Bridge Between Transcription and Function: Role in Liver Metabolism and Disease

(2019) Hui Xia et al.   Frontiers in Endocrinology

IL-33 and IL-18 in Inflammatory Bowel Disease Etiology and Microbial Interactions

(2019) Michelle A. Williams et al.   Frontiers in Immunology

A specific gene-microbe interaction drives the development of Crohn’s disease–like colitis in mice

(2019) R. Caruso et al.   Science Immunology

Alteration of Gut Microbiota in Inflammatory Bowel Disease (IBD): Cause or Consequence? IBD Treatment Targeting the Gut Microbiome

(2019) Israr Khan et al.   Pathogens

BRG1 attenuates colonic inflammation and tumorigenesis through autophagy-dependent oxidative stress sequestration

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Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD

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REDD1/Autophagy Pathway Is Associated with Neutrophil-Driven IL-1β Inflammatory Response in Active Ulcerative Colitis

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Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota

(2018) Ce Tang et al.   NATURE IMMUNOLOGY

Activation of GABAA Receptors in Colon Epithelium Exacerbates Acute Colitis

(2018) Xuelian Ma et al.   Frontiers in Immunology

Attenuation of Rheumatoid Inflammation by Sodium Butyrate Through Reciprocal Targeting of HDAC2 in Osteoclasts and HDAC8 in T Cells

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Interleukin 1α-Deficient Mice Have an Altered Gut Microbiota Leading to Protection from Dextran Sodium Sulfate-Induced Colitis

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Bacteroides thetaiotaomicron Ameliorates Colon Inflammation in Preclinical Models of Crohn’s Disease

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Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis

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Cholesterol as an Endogenous ERRα Agonist: A New Perspective to Cancer Treatment

(2018) Ivan Casaburi et al.   Frontiers in Endocrinology

Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response

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GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections

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Can We Design a Nogo Receptor-Dependent Cellular Therapy to Target MS?

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Bayesian analysis of genome-wide inflammatory bowel disease data sets reveals new risk loci

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Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor−κB, and Up-regulating Expression of MicroRNA-21

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Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor–neutralizing therapy in patients with inflammatory bowel disease

(2017) Nathaniel R West et al.   NATURE MEDICINE

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(2017) Tomoya Iida et al.   WORLD JOURNAL OF GASTROENTEROLOGY

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Transcription factor TFEB cell-autonomously modulates susceptibility to intestinal epithelial cell injury in vivo

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Distinct Microbial Communities Trigger Colitis Development upon Intestinal Barrier Damage via Innate or Adaptive Immune Cells

(2017) Urmi Roy et al.   Cell Reports

Shaping of Intestinal Microbiota in Nlrp6- and Rag2-Deficient Mice Depends on Community Structure

(2017) Eric J.C. Gálvez et al.   Cell Reports

ERRα negatively regulates type I interferon induction by inhibiting TBK1-IRF3 interaction

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Cross sectional evaluation of the gut-microbiome metabolome axis in an Italian cohort of IBD patients

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Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis

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MIR144* inhibits antimicrobial responses against Mycobacterium tuberculosis in human monocytes and macrophages by targeting the autophagy protein DRAM2

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Diverse Intestinal Bacteria Contain Putative Zwitterionic Capsular Polysaccharides with Anti-inflammatory Properties

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The Genomic Context and Corecruitment of SP1 Affect ERRα Coactivation by PGC-1α in Muscle Cells

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Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease

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Constitutive activities of estrogen-related receptors: Transcriptional regulation of metabolism by the ERR pathways in health and disease

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HGF-activated colonic fibroblasts mediates carcinogenesis of colonic epithelial cancer cells via PKC-cMET-ERK1/2-COX-2 signaling

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Orphan Nuclear Receptor ERRα Controls Macrophage Metabolic Signaling and A20 Expression to Negatively Regulate TLR-Induced Inflammation

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(2014) Aleksandar D. Kostic et al.   GASTROENTEROLOGY

Stat3

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(2014) Luigia De Fazio   WORLD JOURNAL OF GASTROENTEROLOGY

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(2013) Györgyi Műzes   WORLD JOURNAL OF GASTROENTEROLOGY

Transient inflammatory-like state and microbial dysbiosis are pivotal in establishment of mucosal homeostasis during colonisation of germ-free mice

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Transcriptional analysis of the intestinal mucosa of patients with ulcerative colitis in remission reveals lasting epithelial cell alterations

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Phylotype-level 16S rRNA analysis reveals new bacterial indicators of health state in acute murine colitis

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Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota

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Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways

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Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

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(2009) Salvatore Modica et al.   GASTROENTEROLOGY

Transcriptional Control of Energy Homeostasis by the Estrogen-Related Receptors

(2008) Vincent Giguère   ENDOCRINE REVIEWS