Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response
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Title
Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response
Authors
Keywords
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Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-12-28
DOI
10.1038/s41467-018-07841-3
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Note: Only part of the references are listed.- DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome
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- Cell-centred meta-analysis reveals baseline predictors of anti-TNFα non-response in biopsy and blood of patients with IBD
- (2018) Renaud Gaujoux et al. GUT
- Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course
- (2018) Melanie Schirmer et al. Cell Host & Microbe
- Roles for Intestinal Bacteria, Viruses, and Fungi in Pathogenesis of Inflammatory Bowel Diseases and Therapeutic Approaches
- (2017) R. Balfour Sartor et al. GASTROENTEROLOGY
- Lessons Learned From Trials Targeting Cytokine Pathways in Patients With Inflammatory Bowel Diseases
- (2017) Clara Abraham et al. GASTROENTEROLOGY
- Understanding and Preventing the Global Increase of Inflammatory Bowel Disease
- (2017) Gilaad G. Kaplan et al. GASTROENTEROLOGY
- Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study
- (2017) Subra Kugathasan et al. LANCET
- Clonal evolution of colorectal cancer in IBD
- (2017) Chang-Ho R. Choi et al. Nature Reviews Gastroenterology & Hepatology
- Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages
- (2017) W. K. Eddie Ip et al. SCIENCE
- Mixture models reveal multiple positional bias types in RNA-Seq data and lead to accurate transcript concentration estimates
- (2017) Andreas Tuerk et al. PLoS Computational Biology
- Effect of vedolizumab (anti-α4β7-integrin) therapy on histological healing and mucosal gene expression in patients with UC
- (2016) Ingrid Arijs et al. GUT
- Peroxisome Proliferator-activated Receptor-γ Coactivator 1-α (PGC1α) Protects against Experimental Murine Colitis
- (2016) Kellie E. Cunningham et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Metabolic flexibility of mitochondrial respiratory chain disorders predicted by computer modelling
- (2016) Łukasz P Zieliński et al. MITOCHONDRION
- Near-optimal probabilistic RNA-seq quantification
- (2016) Nicolas L Bray et al. NATURE BIOTECHNOLOGY
- Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease
- (2016) Walid Mottawea et al. Nature Communications
- Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function
- (2015) Caleb J. Kelly et al. Cell Host & Microbe
- Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
- (2015) Eva M. Palsson-McDermott et al. Cell Metabolism
- Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease
- (2015) Wiebe Vanhove et al. INFLAMMATORY BOWEL DISEASES
- A role for 12/15-lipoxygenase-derived proresolving mediators in postoperative ileus: protectin DX-regulated neutrophil extravasation
- (2015) Kathy Stein et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature
- (2014) Yael Haberman et al. JOURNAL OF CLINICAL INVESTIGATION
- Transcriptome Profiling of Human Ulcerative Colitis Mucosa Reveals Altered Expression of Pathways Enriched in Genetic Susceptibility Loci
- (2014) Christopher J. Cardinale et al. PLoS One
- Mitochondria and Tumor Progression in Ulcerative Colitis
- (2013) Cigdem Himmetoglu Ussakli et al. JNCI-Journal of the National Cancer Institute
- Functional Comparison between Genes Dysregulated in Ulcerative Colitis and Colorectal Carcinoma
- (2013) Wenyuan Zhao et al. PLoS One
- Burden of Gastrointestinal Disease in the United States: 2012 Update
- (2012) Anne F. Peery et al. GASTROENTEROLOGY
- Transcriptional analysis of the intestinal mucosa of patients with ulcerative colitis in remission reveals lasting epithelial cell alterations
- (2012) Núria Planell et al. GUT
- Mitochondrial electron transport chain complex dysfunction in the colonic mucosa in ulcerative colitis
- (2012) Srikanth Santhanam et al. INFLAMMATORY BOWEL DISEASES
- A travel guide to Cytoscape plugins
- (2012) Rintaro Saito et al. NATURE METHODS
- An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea
- (2011) Daniel McDonald et al. ISME Journal
- The expression of REG 1A and REG 1B is increased during acute amebic colitis
- (2011) Kristine M. Peterson et al. PARASITOLOGY INTERNATIONAL
- Eosinophils promote resolution of acute peritonitis by producing proresolving mediators in mice
- (2010) Tomohiro Yamada et al. FASEB JOURNAL
- Severe Pediatric Ulcerative Colitis: A Prospective Multicenter Study of Outcomes and Predictors of Response
- (2010) Dan Turner et al. GASTROENTEROLOGY
- Clinical variables as prognostic tools in pediatric-onset ulcerative colitis: A retrospective cohort study
- (2010) Jill C. Moore et al. INFLAMMATORY BOWEL DISEASES
- Resolution of Inflammation in Murine Autoimmune Arthritis Is Disrupted by Cyclooxygenase-2 Inhibition and Restored by Prostaglandin E2-Mediated Lipoxin A4 Production
- (2010) M. M. Y. Chan et al. JOURNAL OF IMMUNOLOGY
- Mitochondrial respiratory chain in the colonic mucosal of patients with ulcerative colitis
- (2010) Karla G. Sifroni et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- ToppCluster: a multiple gene list feature analyzer for comparative enrichment clustering and network-based dissection of biological systems
- (2010) V. Kaimal et al. NUCLEIC ACIDS RESEARCH
- Influence of Phenotype at Diagnosis and of Other Potential Prognostic Factors on the Course of Inflammatory Bowel Disease
- (2009) M J L Romberg-Camps et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
- (2009) Gabriela Bindea et al. BIOINFORMATICS
- ToppGene Suite for gene list enrichment analysis and candidate gene prioritization
- (2009) J. Chen et al. NUCLEIC ACIDS RESEARCH
- Mucosal Gene Expression of Antimicrobial Peptides in Inflammatory Bowel Disease Before and After First Infliximab Treatment
- (2009) Ingrid Arijs et al. PLoS One
- Clonality, Founder Mutations, and Field Cancerization in Human Ulcerative Colitis–Associated Neoplasia
- (2008) Simon J. Leedham et al. GASTROENTEROLOGY
- Activation of an IL-6:STAT3-dependent transcriptome in pediatric-onset inflammatory bowel disease
- (2007) Rebecca Carey et al. INFLAMMATORY BOWEL DISEASES
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