Burden of influenza B virus infection and considerations for clinical management

Global update on the susceptibilities of human influenza viruses to neuraminidase inhibitors and the cap-dependent endonuclease inhibitor baloxavir, 2017–2018

(2020) Emi Takashita et al.   ANTIVIRAL RESEARCH

Favipiravir and Zanamivir Cleared Infection with Influenza B in a Severely Immunocompromised Child

(2020) Casper K Lumby et al.   CLINICAL INFECTIOUS DISEASES

Early Administration of Oseltamivir Within 48 Hours After Onset of Flulike Symptoms Can Reduce the Risk of Influenza B Virus-Associated Pneumonia in Hospitalized Pediatric Patients with Influenza B Virus Infection

(2020) Zhichu Dai et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

A phase 2 randomized, double-blind, placebo-controlled trial of MHAA4549A, a monoclonal antibody, plus oseltamivir in patients hospitalized with severe influenza A infection

(2020) Jeremy J Lim et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Safety and effectiveness of baloxavir marboxil for the treatment of influenza in Japanese clinical practice: A postmarketing surveillance of more than 3000 patients

(2020) Masami Nakazawa et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Baloxavir Marboxil 2% Granules in Japanese Children With Influenza

(2020) Takato Yokoyama et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Early treatment with baloxavir marboxil in high-risk adolescent and adult outpatients with uncomplicated influenza (CAPSTONE-2): a randomised, placebo-controlled, phase 3 trial

(2020) Michael G Ison et al.   LANCET INFECTIOUS DISEASES

Baloxavir Marboxil for Prophylaxis against Influenza in Household Contacts

(2020) Hideyuki Ikematsu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Baloxavir Marboxil Single-dose Treatment in Influenza-infected Children

(2020) Jeffrey Baker et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Cross-lineage protection by human antibodies binding the influenza B hemagglutinin

(2019) Yi Liu et al.   Nature Communications

Safety and efficacy of monoclonal antibody VIS410 in adults with uncomplicated influenza A infection: Results from a randomized, double-blind, phase-2, placebo-controlled study

(2019) Ellie Hershberger et al.   EBioMedicine

Influenza virus polymerase inhibitors in clinical development

(2019) Frederick G. Hayden et al.   CURRENT OPINION IN INFECTIOUS DISEASES

In vitro neuraminidase inhibitory concentration (IC50) of four neuraminidase inhibitors in the Japanese 2017–18 season: Comparison with the 2010–11 to 2016–17 seasons

(2019) Hideyuki Ikematsu et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Emerging Influenza D Virus Threat: What We Know so Far!

(2019) Kumari Asha et al.   Journal of Clinical Medicine

Comparative global epidemiology of influenza, respiratory syncytial and parainfluenza viruses, 2010–2015

(2019) Tommy T Lam et al.   JOURNAL OF INFECTION

Antivirals targeting the polymerase complex of influenza viruses

(2019) Edin J. Mifsud et al.   ANTIVIRAL RESEARCH

Baloxavir marboxil in Japanese pediatric patients with influenza: safety and clinical and virologic outcomes

(2019) Nobuo Hirotsu et al.   CLINICAL INFECTIOUS DISEASES

Viral Kinetics and Resistance Development in Children Treated with Neuraminidase Inhibitors: The Influenza Resistance Information Study (IRIS)

(2019) Rueshandra Roosenhoff et al.   CLINICAL INFECTIOUS DISEASES

The epidemiological signature of influenza B virus and its B/Victoria and B/Yamagata lineages in the 21st century

(2019) Saverio Caini et al.   PLoS One

Anti-influenza hyperimmune intravenous immunoglobulin for adults with influenza A or B infection (FLU-IVIG): a double-blind, randomised, placebo-controlled trial

(2019) Richard T Davey et al.   Lancet Respiratory Medicine

New antibody-based prevention and treatment options for influenza

(2019) Koen Sedeyn et al.   ANTIVIRAL RESEARCH

Co-circulation of the two influenza B lineages during 13 consecutive influenza surveillance seasons in Italy, 2004–2017

(2019) Simona Puzelli et al.   BMC INFECTIOUS DISEASES

Pharmacokinetics and Pharmacodynamics of Conventional-Dose vs Triple-Dose Oseltamivir in Severely Immunocompromised Children With Influenza

(2019) Francisco Bautista et al.   Open Forum Infectious Diseases

Divergent evolutionary trajectories of influenza B viruses underlie their contemporaneous epidemic activity

(2019) Ramandeep K. Virk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Literature review of the epidemiology of influenza B disease in 15 countries in the Asia-Pacific region

(2018) Lance Jennings et al.   Influenza and Other Respiratory Viruses

Clinical characteristics and severity of influenza infections by virus type, subtype, and lineage: A systematic literature review

(2018) Saverio Caini et al.   Influenza and Other Respiratory Viruses

Clinical effectiveness of four neuraminidase inhibitors (oseltamivir, zanamivir, laninamivir, and peramivir) for children with influenza A and B in the 2014–2015 to 2016–2017 influenza seasons in Japan

(2018) Nobuhisa Ishiguro et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Influenza-Associated Pediatric Deaths in the United States, 2010–2016

(2018) Mei Shang et al.   PEDIATRICS

Influenza

(2018) Florian Krammer et al.   Nature Reviews Disease Primers

Molecular characterization of a nosocomial outbreak of influenza B virus in an acute care hospital setting

(2018) M. Sansone et al.   JOURNAL OF HOSPITAL INFECTION

Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents

(2018) Frederick G. Hayden et al.   NEW ENGLAND JOURNAL OF MEDICINE

Influenza A/H3N2 virus infection in immunocompromised ferrets and emergence of antiviral resistance

(2018) Rueshandra Roosenhoff et al.   PLoS One

In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit

(2018) Takeshi Noshi et al.   ANTIVIRAL RESEARCH

Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenzaa

(2018) Timothy M Uyeki et al.   CLINICAL INFECTIOUS DISEASES

1645. Exploring Clinical and Antiviral Efficacy of Baloxavir Marboxil in a Phase 3, Randomized, Double-Blind, Placebo- and Active-Controlled Study of Otherwise Healthy Adults/Adolescents in Seasonal Influenza: Impact on Regional Participants, Treatment Time and Influenza Type B Virus Infection (CAPSTONE-1 Study)

(2018) Keiko Kawaguchi et al.   Open Forum Infectious Diseases

Outbreaks of influenza B infection and pneumococcal pneumonia at a mental health facility in Japan

(2017) Yoshitaka Yamazaki et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Structures of human-infectingThogotovirusfusogens support a common ancestor with insect baculovirus

(2017) Ruchao Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide evolutionary dynamics of influenza B viruses on a global scale

(2017) Pinky Langat et al.   PLoS Pathogens

The Next Wave of Influenza Drugs

(2017) Megan L. Shaw   ACS Infectious Diseases

Knowns and unknowns of influenza B viruses

(2016) Marios Koutsakos et al.   Future Microbiology

Influenza Neuraminidase Inhibitors: Synthetic Approaches, Derivatives and Biological Activity

(2016) Pedro Laborda et al.   MOLECULES

Hospitalization for Influenza A Versus B

(2016) D. Tran et al.   PEDIATRICS

A comprehensive review of the epidemiology and disease burden of Influenza B in 9 European countries

(2016) Monica Tafalla et al.   Human Vaccines & Immunotherapeutics

Influenza B viruses: not to be discounted

(2015) Carolien E van de Sandt et al.   Future Microbiology

Characterisation of nosocomial and community-acquired influenza in a large university hospital during two consecutive influenza seasons

(2015) Daniela Huzly et al.   JOURNAL OF CLINICAL VIROLOGY

Outcomes and Susceptibility to Neuraminidase Inhibitors in Individuals Infected With Different Influenza B Lineages: The Influenza Resistance Information Study

(2015) Erhard van der Vries et al.   JOURNAL OF INFECTIOUS DISEASES

The contrasting phylodynamics of human influenza B viruses

(2015) Dhanasekaran Vijaykrishna et al.   eLife

Preclinical Activity of VX-787, a First-in-Class, Orally Bioavailable Inhibitor of the Influenza Virus Polymerase PB2 Subunit

(2014) Randal A. Byrn et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparing Clinical Characteristics Between Hospitalized Adults With Laboratory-Confirmed Influenza A and B Virus Infection

(2014) S. Su et al.   CLINICAL INFECTIOUS DISEASES

Case series of rash associated with influenza B in school children

(2014) Danuta M. Skowronski et al.   Influenza and Other Respiratory Viruses

The Burden of Influenza B: A Structured Literature Review

(2013) W. Paul Glezen et al.   AMERICAN JOURNAL OF PUBLIC HEALTH

Favipiravir (T-705), a novel viral RNA polymerase inhibitor

(2013) Yousuke Furuta et al.   ANTIVIRAL RESEARCH

Neuraminidase inhibitors for influenza B virus infection: Efficacy and resistance

(2013) Andrew J. Burnham et al.   ANTIVIRAL RESEARCH

Comparing influenza vaccine efficacy against mismatched and matched strains: a systematic review and meta-analysis

(2013) Andrea C Tricco et al.   BMC Medicine

A Prospective Intervention Study on Higher-Dose Oseltamivir Treatment in Adults Hospitalized With Influenza A and B Infections

(2013) N. Lee et al.   CLINICAL INFECTIOUS DISEASES

Comparison of the clinical effectiveness of zanamivir and laninamivir octanoate for children with influenza A(H3N2) and B in the 2011-2012 season

(2013) Naoko Koseki et al.   Influenza and Other Respiratory Viruses

In vitro neuraminidase inhibitory activity of four neuraminidase inhibitors against influenza virus isolates in the 2011–2012 season in Japan

(2013) Hideyuki Ikematsu et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Surveillance and Vaccine Effectiveness of an Influenza Epidemic Predominated by Vaccine-Mismatched Influenza B/Yamagata-Lineage Viruses in Taiwan, 2011−12 Season

(2013) Yi-Chun Lo et al.   PLoS One

Influenza B Lineage Circulation and Hospitalization Rates in a Subtropical City, Hong Kong, 2000–2010

(2012) Paul K. S. Chan et al.   CLINICAL INFECTIOUS DISEASES

The Coming Era of Quadrivalent Human Influenza Vaccines

(2012) Ian G. Barr et al.   DRUGS

Unexpected severity of cases of influenza B infection in patients that required hospitalization during the first postpandemic wave

(2012) A. Gutiérrez-Pizarraya et al.   JOURNAL OF INFECTION

Myocardial Injury and Bacterial Pneumonia Contribute to the Pathogenesis of Fatal Influenza B Virus Infection

(2012) Christopher D. Paddock et al.   JOURNAL OF INFECTIOUS DISEASES

Seasonal influenza vaccine efficacy and its determinants in children and non-elderly adults: A systematic review with meta-analyses of controlled trials

(2012) Carlos A. DiazGranados et al.   VACCINE

Antiviral resistance during the 2009 influenza A H1N1 pandemic: public health, laboratory, and clinical perspectives

(2011) Aeron C Hurt et al.   LANCET INFECTIOUS DISEASES

A Large Outbreak of Influenza B-associated Benign Acute Childhood Myositis in Germany, 2007/2008

(2011) Sabine Mall et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Early Oseltamivir Treatment of Influenza in Children 1–3 Years of Age: A Randomized Controlled Trial

(2010) Santtu Heinonen et al.   CLINICAL INFECTIOUS DISEASES

Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses

(2010) Aaron J. Oakley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Detection of antiviral resistance and genetic lineage markers in influenza B virus neuraminidase using pyrosequencing

(2009) Tiffany G. Sheu et al.   ANTIVIRAL RESEARCH

The use of oseltamivir during an influenza B outbreak in a chronic care hospital

(2009) Holly Seale et al.   Influenza and Other Respiratory Viruses

Comparison of the Clinical Effectiveness of Oseltamivir and Zanamivir against Influenza Virus Infection in Children

(2008) Norio Sugaya et al.   CLINICAL INFECTIOUS DISEASES

Effectiveness of Oseltamivir Treatment among Children with Influenza A or B Virus Infections during Four Successive Winters in Niigata City, Japan

(2008) Maki Sato et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE